scholarly journals Socio-demographic and Clinical Profile of Children with Asthma attending Chest Clinic at B. P. Koirala Institute of Health Sciences, Nepal

2021 ◽  
Vol 6 (2) ◽  
pp. 1426-1431
Author(s):  
Satish Yadav

Introduction: Asthma in children is one of the most common chronic diseases and little information available on factors associated with this disease in our part of the world. Objective:  The present study is an attempt to find out the socio-demographic and clinical profile of children with asthma. Methodology: This was a retrospective analysis of data of asthmatic children below 14 years attending pediatric chest clinic from July 2014 till March 2016. Results:  Of the 200 children, there were 142 (71%) males. The median age of presentation was 3 years and 139 (69.5%) from the age group 1-5years One third had poorly controlled asthma. Comorbidity was present in 59(29.5%) and allergic rhinitis (7%) was the most common. 90.5% had onset of wheezing before 5 years of age. Family history of asthma and/or atopy and smoking was present in 24% and 31%, respectively. 22% had exposure to pet animals. Upper respiratory tract infection (URTI) (37%) was the most common trigger for exacerbation. Cough (99%) and fast breathing (98%) were the most common symptoms. Conclusion: The majorities were males of young age with rhinitis as most common co-morbidity and many of them had a history of parental smoking at home. One third of them had poorly controlled asthma which shows the need for proper management of asthma including its comorbidity in younger children and changing certain habits like parental smoking at home.

2019 ◽  
Vol 6 (4) ◽  
pp. 1089
Author(s):  
Arundhati Diwan ◽  
Supriya Barsode ◽  
Chandrakant Chavan ◽  
Rohit Jakhotia ◽  
Krishnapriya Vadlapatla

Background: Pulmonary embolism is a common and potentially life threatening condition. Most patients who succumb to pulmonary embolism do so within the first few hours of the event. The aim of the study was to observe the clinical profile, management and outcome in patients of pulmonary embolism.Methods: A prospective observational study was conducted in the Department of Medicine in a Tertiary care hospital in Western Maharashtra for a period of two years. 55 patients with confirmed diagnosis on CTPA (Computed tomography pulmonary angiography) were included in our study. A detailed history, examination and investigations like D dimer were done in all cases.Results: Mean age of the study cases was 44.98 years with 40% of the cases between 31-50 years of age. Overall male predominance was seen (83.6%). Most common associated co-morbidity was diabetes (32.7%). The commonest risk factor seen in the present study was history of smoking (29.1%). Dyspnoea was the most common presenting complaint (72.7%). Commonest presenting sign was tachycardia (43.6%). In present study, mortality rate among cases of pulmonary embolism was observed as 3.6%..Conclusions: Mean age of the study cases was 44.98 years with 40% of the cases between 31-50 years of age. Overall male predominance was seen (83.6%). Most common associated co-morbidity was diabetes (32.7%). The commonest risk factor seen in the present study was history of smoking (29.1%). Dyspnoea was the most common presenting complaint (72.7%). Commonest presenting sign was tachycardia (43.6%). In present study, mortality rate among cases of pulmonary embolism was observed as 3.6%.


2021 ◽  
pp. 167-170
Author(s):  
Sunita Das ◽  
Deshish Kumar Panda ◽  
Kedarnath Das ◽  
Saiprasanna Behera

This hospital based observational cross sectional study having a sample size of 100 was undertaken at S.C.B. Medical College and S.V.P.P.G.I.P.,Cuttack,with an objective to study the clinical profile and risk factors for wheezing in infancy from November 2018 to November 2020. Wheezing is accountable for a high demand of medical consultations and emergency care services with relatively high rates of hospitalization.In this study, several risk factors were identified for wheezing in less than one year of age which had little resemblance to similar studies made in various other age groups.However,maternal smoking as a risk factor could not be found in our study due to social cultural lifestyle in the study population. Factors like caesarean section, history of birth asphyxia, NICU admissions and living in kuccha house were not found to impose risk for wheezing in infancy in the study in contrary to similar such studies in other age groups.The present study revealed, that among all other etiology, the viral respiratory tract infections including bronchiolitis was the most common cause of wheezing in infancy (64%) followed by WALRI (wheeze associated lower respiratory tract infection). In conclusion, if an infant with wheezing has risk factors like male sex, preterm, more than six months age, family history of atopy or repeated upper respiratory tract illness or overcrowding in family, anticipating the severity recurrence should be suspected. These infants should be monitored closely for signs of clinical deterioration. Proper health education,ante natal and neonatal care,promoting of breast feeding and creating awareness to the public regarding modifiable risk factors like separation of family members having upper respiratory illness from young infants will reduce the severity of wheezing and will help prevent their recurrence to much extent.


1970 ◽  
Vol 5 (2) ◽  
pp. 75-79
Author(s):  
Jesmin Ara Begum ◽  
Mohammad Imnul Islam ◽  
Abdul Matin

Background: Asthma is one of the important chronic disorder in childhood, the incidence of paediatric asthma is increasing in many countries. Atopy is highly associated with childhood asthma. Spirometric measurements of lung function are playing a key role in the diagnosis and management of asthma in children. Objective: To observe the lung function status in asthmatic children aged 6-15 years of both sexes. Method: The present observational study was carried out in the Department of Physiology, Ibrahim Medical College, Dhaka between January 2010 and June 2010. For this, 30 asthmatic children were selected from Out Patient Department of Paediatric, Dhaka Medical College as a case and 30 apparently healthy children were taken as control. Subjects with history of pneumonia, congenital heart disease were excluded from the study. Spirometry was conducted on all patients by using Spirolab a new generation spirometer according to American Thoracic Society standards FEV1, FVC, FEV1/FVC% were measured. Measurement of PEFR was also done at the same time by using a new Mini-Wright Peak Flow Meter. Serum Ig-E level was measured by ELISA method and circulating eosinophil count was also measured by observing in peripheral blood flim. Data were analyzed by using SPSS. Statistical analysis was performed by unpaired student t test. Results: The mean percentages of predicted values FEV1, FVC, FEV1/FVC%, PEFR were significantly lower in asthmatic children compared to those of apparently healthy children(P<0.001). Statistically significant differences of mean circulating eosinophil count and Ig E level( P<0.001) were observed between the groups. Again significant number of parents of the subject had history of allergic rhinitis. Conclusion: The outcome of this study shows lung function status were lower in asthmatic children. DOI: 10.3329/jbsp.v5i2.6781J Bangladesh Soc Physiol. 2010 December; 5(2): 75-79


2021 ◽  
pp. 004947552110196
Author(s):  
Serife Torun ◽  
Irem Karaman

Leprosy is an ancient ailment, also known as Hansen’s disease. It primarily involves the superficial peripheral nerves, skin, upper respiratory tract mucosa, eyes, bones and testicles, but not the lungs. Although leprosy patients are not included in the study area of pulmonology, here we present an undiagnosed leprosy patient with a history of smoking, who was referred owing to upper respiratory tract symptoms and bilateral pleural effusions. From this undiagnosed case, we would like to draw specific attention of pulmonologists, since a patient with leprosy can present in this way due to hypoalbuminemia resulting from a systemic inflammatory state, which may then progress to sepsis. Collaboration of different specialists may be required to clinch extra-neurological and extra-cutaneous features of leprosy.


2018 ◽  
Vol 18 (2) ◽  
pp. 161 ◽  
Author(s):  
Mohammad Al-Motlaq ◽  
Nihaya Al-Sheyab

Objectives: This study aimed to examine non-asthmatic children’s acceptance of and attitudes towards their asthmatic peers in Jordan. Methods: This descriptive cross-sectional study was conducted between September 2015 and January 2016 among 1,812 non-asthmatic children aged 9–13 years old at 10 schools in Zarqa, Jordan. Arabic versions of the Peers Attitude Towards Children with Asthma scale and the Asthma Knowledge Test for Children were used to assess attitudes towards children with asthma and asthma-related knowledge, respectively. Results: A total of 1,586 children participated in the study (response rate: 87.5%). Of these, 158 (10%) and 399 (25.2%) children reported a family history of asthma or knew at least one person with asthma, respectively. Although 50.3% stated that they would sit next to such children in the classroom, only 34.9% reported that they would be friends with an asthmatic child. However, 73.1% of the non-asthmatic children believed that asthmatic children were not pretending to be ill and 61.4% believed that such children were not ill due to their own carelessness. Female non-asthmatic children (P <0.001), those with a family history of asthma (P = 0.004) and those who knew other individuals with asthma (P <0.001) had significantly more positive attitudestowards and acceptance of their asthmatic peers. In addition, age was significantly related to attitude scores (P <0.001). However, there was no correlation between asthma-related knowledge and the children’s attitudes towards peers with asthma (P = 0.611). Conclusion: Previous interactions with asthmatic family members or peers were found to significantly influence non-asthmatic children’s attitudes towards their asthmatic peers.Keywords: Asthma; Children; Attitudes; Knowledge; Jordan.


1999 ◽  
Vol 45 (4) ◽  
pp. 505-509 ◽  
Author(s):  
Christiane Oddoze ◽  
Jean Christophe Dubus ◽  
Monique Badier ◽  
Xavier Thirion ◽  
Anne Marie Pauli ◽  
...  

Abstract Background: Studies of the effects of tobacco smoke often rely on reported exposure to cigarette smoke, a measure that is subject to bias. We describe here the relationship between parental smoking exposure as assessed by urinary cotinine excretion and lung function in children with asthma. Methods: We studied 90 children 4–14 years of age, who reported a confirmed diagnosis or symptoms of asthma. In each child, we assessed baseline pulmonary function (spirometry) and bronchial responsiveness to carbachol stimulation. Urinary cotinine was measured by HPLC with ultraviolet detection. Results: Urinary cotinine concentrations in the children were significantly correlated (P &lt;0.001) with the number of cigarettes the parents, especially the mothers, smoked. Bronchial responsiveness to carbachol (but not spirometry test results) was correlated (P &lt;0.03) with urinary cotinine in the children. Conclusion: Passive smoke exposure increases the bronchial responsiveness to carbachol in asthmatic children.


2004 ◽  
Vol 43 (06) ◽  
pp. 217-220 ◽  
Author(s):  
J. Dressler ◽  
F. Grünwald ◽  
B. Leisner ◽  
E. Moser ◽  
Chr. Reiners ◽  
...  

SummaryThe version 3 of the guideline for radioiodine therapy for benign thyroid diseases presents first of all a revision of the version 2. The chapter indication for radioiodine therapy, surgical treatment or antithyroid drugs bases on an interdisciplinary consensus. The manifold criteria for decision making consider the entity of thyroid disease (autonomy, Graves’ disease, goitre, goitre recurrence), the thyroid volume, suspicion of malignancy, cystic nodules, risk of surgery and co-morbidity, history of subtotal thyroidectomy, persistent or recurrent thyrotoxicosis caused by Graves’ disease including known risk factors for relapse, compression of the trachea caused by goitre, requirement of direct therapeutic effect as well as the patient’s preference. Because often some of these criteria are relevant, the guideline offers the necessary flexibility for individual decisions. Further topics are patients’ preparation, counseling, dosage concepts, procedural details, results, side effects and follow-up care. The prophylactic use of glucocorticoids during radioiodine therapy in patients without preexisting ophthalmopathy as well as dosage and duration of glucocorticoid medication in patients with preexisting ophthalmopathy need to be clarified in further studies. The pragmatic recommendations for the combined use of radioiodine and glucocorticoids remained unchanged in the 3rd version.


The Lake Rudolf Rift Valley Expedition was designed to carry out many different lines of investigation in the Lake Rudolf Basin. One of the chief of these was a study of the geological history of that part of the East African Rift Valley. The expedition was assisted financially by The Royal Society, The Geological Society of London, The Royal Geographical Society, The Percy Sladen Trustees and the Geographical and Geological Sections of the British Association. A general description of the activities of the Expedition was given in a paper read before the Royal Geographical Society (Fuchs 1935). Owing to the tragic loss of two members of the expedition, Dr W. S. Dyson and Mr W. R. H. Martin, two fruitless months were spent searching for them. Consequently a great amount of the work planned for the east side of the lake had to be abandoned. Nevertheless, the considerable distance travelled within the 50,000 sq. miles of the Rudolf Basin has enabled me to make out the chief events of its geological history. I am very much indebted to all those who assisted us in the field and at home, in particular to the Kenya Government, the Officers of the King’s African Rifles, and Mr H. L. Sikes of the Public Works Department; I would also like to thank Mr A. M. Champion, Provincial Commissioner of Turkana, who wholeheartedly assisted us in every way possible both in the field and at home, for he has placed at my disposal his own excellent topographical maps and his extensive observations on the geology of the area. I am also deeply indebted to Professor O. T. Jones, Mr Henry Woods and Mr W. Campbell Smith for their criticisms. Mr Campbell Smith has also given me provisional identifications of the rocks.


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