scholarly journals Profile of Anaemia in HIV Positive Patients

2016 ◽  
Vol 12 (2) ◽  
pp. 70-73 ◽  
Author(s):  
Khem Raj Bhusal ◽  
Surya Devkota ◽  
Midhan Shrestha ◽  
Prem Khadga

Background & Objectives: This was a cross-sectional observational study designed to see the prevalence of anemia among HIV positive patients and its correlation with CD4 counts.Materials & Methods: Fifty five HIV/AIDS patients presented for the first time to Tribhuwan University Teaching Hospital [TUTH] were enrolled in the study. Patients' duration of HIV positivity, history regarding ART and duration, history of associated co morbid or opportunistic conditions were taken, CD4 counts, RFT, CBC test results were recorded. Patients' clinical and laboratory parameters were recorded. Anaemia was classified by WHO criteria for both men and women.Results: Out of 55 patients, 23 (42 %) had anemia, out of which 14 (60.87 %) had mild anemia (anemia but Hb not less than 9.5g/dl), four (17.39%) had moderate anemia (Hb 8 to 9.4 g/ dL) and two (8.7%) had severe anemia (Hb 6.5 to 7.9 g/dL) and three (13.04%) had very severe or life threatening anemia (Hb less than 6.5 g/dL). Corresponding odds ratio from stage CD4 counts<200 to CD4 counts >/= 200 for anemia was 4.55 times; which is statistically significant (p<0.0001). There was negative association between the prevalence of anemia and HIV stage (CD4 count).Conclusion: There was high prevalence of anemia and severity of immunodeficiency directly correlates with degree of anemia. Degree of anemia can be easily assessed even in rural clinical setting, hence degree of immunodeficiency can early be detected in all settings.JCMS Nepal. 2016;12(2):70-3

2018 ◽  
Vol 4 (2) ◽  
pp. 17-19
Author(s):  
Nabin Rayamajhi ◽  
Satyendra Kumar Mishra ◽  
Narayan Gautam ◽  
Nilesh Raj Doshi

INTRODUCTION: In South Asian Region, the prevalence of anemia among pregnant women has been estimated to be 75% which is highest in the world. Hence, this study was drafted to evaluate the prevalence of anemia in pregnant women in western part of NepalMATERIALS AND METHODS: It was a hospital based cross-sectional study. A total of 200 pregnant ladies aged 15-45 years giving consent for the study were included and their detailed medical history, clinical examination and lab investigations focusing on hematological parameters were documented. Data were entered in excel sheet and analysed by SPSS (17.0).RESULTS: The prevalence of anemia in pregnant women was 48% with increased prevalence as the pregnancy proceeds and reaching its highest during third trimester of pregnancy. Young adults with age ranging from 15-30 years had highest prevalence of anemia. Mild anemia (Hb: 9-10.9 g/dl) was the commonest entity.CONCLUSION: With this high prevalence, screening for anemia during pregnancy should be done. Moreover, exogenous supplementation of iron capsules or diet rich in iron can be advised to those anaemic pregnant women.Journal of Universal College of Medical Sciences (2016)Vol.04 No.02 Issue 14, page: 17-19 


Author(s):  
Ignace N. Yao ◽  
Jean Marc L. Dia ◽  
Michelle M. Menin ◽  
Mouhedeen A. Oyelade ◽  
Corneille T. Saki ◽  
...  

Background: Describe the epidemiological and diagnostic of spontaneous aspects of early miscarriage in the department of the Gynecology Obsteric of Treichville University Teaching Hospital of   Treichville in Abidjan.Methods: A cross-sectional study was performed from January 2016 to March 2017 on patients received for an early miscarriage (gestational age less than 14 weeks of amenorrhea).Results: We recorded 337 cases of miscarriage and it shows that miscarriage was frequently estimated at 58 percent. Our patients had a average age of 32.9 years, 60.4 percent of them with primary education and 48 percent are housewives. The patients were paucigestes in 46 percent and the majority of them were nulliparous (62 percent). 6 percent with history of high blood pressure; diabetes (3 percent) and 31 percent of patients were HIV positive. Patients had pelvic pain at the admission in (55 percent). A miscarriage appears before 10 weeks of amenorrhea (76.1 percent) of cases. Ultrasound showed ovular debris (47 percent) of patients and (55.4 percent) were chromosomal abnormalities on anatomy-pathological examination.Conclusions: Spontaneous abortions are common and pathological examination is essential for diagnosis.


Author(s):  
Azad K. L. ◽  
Dwivedi S. K.

Background: It has been estimated that 1.62 billion population of the world are suffering from anemia. Preschool children show a highest prevalence of 47.4%. Adult males show a lowest prevalence of 12.7% of anemia. Objective was to study the profile of patients with different degrees of anemia.Methods: Over a period of seven months, from January 2014 to July 2014, a cross sectional study was conducted at department of pathology, Lt. BRKM government medical college, Jagdalpur, Chhattisgarh, India. It was possible to study the 250 cases during the tenure of the study period for the present study.Results: It was found that only 3.2% of cases were not having anemia. Thus, the overall prevalence of anemia in the present study was found out to be 96.8%. 62.5% of males and 37.5% of females were having normal hemoglobin. It was found that with normal hemoglobin of more than 12 gm%, no case was having serum iron less than 10.6 µmol/l. All cases without anemia had normal serum iron. 30.3% of cases of anemia had normal serum iron levels. 75.6% of cases across all degrees of anemia were showing microcytosis. This was more in moderate anemia having hemoglobin of 6-9 gm% followed by 42.4% in cases having mild anemia of hemoglobin of 9-12 gm%. Only 13.5% with severe degree of anemia were showing the microcytosis. 24.4% of cases were showing the normocytosis whereas no case has shown the macrocytosis.Conclusions: Prevalence of anemia was more in females. Serum iron did not correspond with the degree of anemia. There is need to emphasize more on awareness about anemia and its prevention especially in mother and child age group.


2021 ◽  
Author(s):  
Belete Gelaw ◽  
Chalie Marew ◽  
Tigabu Dessie ◽  
Nigusie Selomon ◽  
Moges Wubneh ◽  
...  

Abstract Background: Malnutrition is very common in HIV infected individual due to decreased food intake, altering digestion, absorption and altering metabolism and by increasing energy need. Even though data from different settings are necessary to tackle it, evidences are limited especially in case of nutritional status of HIV-infected children. Hence, this study aims to assess the nutritional status and associated factors among children on antiretroviral therapy. Methods: An institutional-based cross-sectional study was conducted among 383 HIV-positive children in Southern Ethiopia. Data were collected using interviewer administered questionnaire and anthropometry measurement. Data were coded and entered into Epi-Data Version 3.1, and analyzed using SPSS Version 25. Bivariable and multivariable binary logistic regression models were used to identify factors associated with nutritional status and variables with p-values ˂0.05 in multivariable logistic regression were considered as statistically significant factors.Results: The prevalence of wasting among HIV positive children in Southern Ethiopia selected Hospitals was 36.3% (95% CI: 31.6, 41.0), while stunting on the same study population was 5.5% (95% CI: 3.4, 7.8). Rural residence (AOR = 4.1, CI: 2.0, 8.4), lack of maternal education (AOR =9.3, CI: 5.0, 17.3), low CD4 counts (<500) (AOR =4.9, CI: 2.3, 10.4), using unprotected water source (AOR = 3.2, CI: 1.8, 5.8), having non-biological mother (AOR =4.2, CI: 1.9, 9.2) and recurrent oral lesion (AOR =2.2, CI:1.2, 4.2) were significantly associated with wasting. Furthermore, history of hospital admission (AOR =4.9, CI: 1.6, 15.0), recurrent oral lesion (AOR =3.9, CI: 1.1, 14.1), low CD4 counts (< 500) (AOR =3.5, CI: 1.0-12.0), advanced WHO clinical stage III (AOR =4.0, CI: 1.1, 14.2) were statically associated with stunting. Conclusion: This study found that the prevalence of under-nutrition among HIV-positive children in Ethiopia was significantly high. Rural residence, lack of maternal education, low CD4 count, recurrent oral lesion, having none-biological caretakers and unprotected source of water were significantly associated with childhood wasting. On the other hand, history of hospital admission, recurrent oral lesion, advanced WHO clinical stage and low CD4 counts were significantly associated with stunting of HIV positive children. Therefore, timely identification and monitoring of nutritional problems should be necessary to enhance the effectiveness of ART treatment and to prevent further related complications.


2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Rian Diana ◽  
Ali Khomsan ◽  
Faisal Anwar ◽  
Dyan Fajar Christianti ◽  
Rendra Kusuma ◽  
...  

Dietary diversity and quantity are important for pregnant women, particularly anemic pregnant women. This study aimed to analyze the association between dietary quantity and diversity among anemic pregnant women. This cross-sectional study was conducted in 2017 at Madura Island, Indonesia, and involved 152 anemic pregnant women. Hemoglobin concentration was analyzed by the cyanmethemoglobin method. Dietary quantity was measured by the 2 × 24 h recall. Dietary diversity was determined by Minimum Dietary Diversity for Women of Reproductive Age (MDD-W). Spearman’s rank association was performed to analyze the association between dietary diversity and quantity. The median of hemoglobin concentration was 10.1 g/dL, and 57.2% pregnant women had mild anemia. Most of the pregnant women had low adequacy levels of energy and macro- and micronutrients (except for iron). More than half (57.9%) of anemic pregnant women had reached minimum dietary diversity. Family size (p=0.048) and gestational age (p=0.004) had negative associations with dietary diversity. Dietary diversity had positive associations with energy (p=0.029), protein (p=0.003), vitamin A (p=0.001), vitamin C (p=0.004), and zinc (p=0.015) adequacy levels. Dietary diversity had no significant association with calcium (p=0.078) and iron adequacy level (p=0.206). High prevalence of mild and moderate anemia was found among pregnant women in their third trimester. Anemic pregnant women already consumed food with minimum dietary diversity but did not meet dietary quantity. Increasing dietary quantity is a priority for anemic pregnant women.


2021 ◽  
Vol 12 (4) ◽  
pp. 833-838
Author(s):  
Aboli Patil ◽  
Rajanish Meti ◽  
Swapnil C R ◽  
Mahesh Parappagoudra ◽  
Parikshit Kumar

Anemia is one of the associated and underlying health conditions observed in large number of school going children of rural India. National Family Health Survey (NHFS) data published by Government of Indiaindicates increased prevalence ofanaemia in children of rural India. In the present study, children of government school of the Waghodia tehsil, Vadodara district Gujarat were surveyed. A cross sectional study was conducted to survey 500 children of either genderaccording to WHO gradation as normal range (12.6 ± 0.54 gm/dl); mild anemia (11.01 ± 0.58gm/dl) and moderate anemia(9.11 ± 0.3gm/dl).Observations indicated that, 20.6%, 74.8% and 4.6%children were in normal or above normal range, mild anemia and moderate anemia respectively. Overall79.4% of children have anemia.  It reveals the escalating magnitude of prevalence of IDA in rural Gujarat. Prevalence is more in 9-11 age group (56%). Gender wise distribution shows mild and moderate anemia in 305 (80.9%) and 14 (3.7%) respectively amongst 377 male children; whereas mild anemia and moderate anemia in 305 (80.9%) and 14 (3.7%) respectively amongst 123 female children. In nutshell, prevalence of anemia is prominent in children of age group in different rural parts of Gujarat. 


2020 ◽  
Vol 2 (4) ◽  
Author(s):  
Shweta R Singh ◽  
Bunsoth Mao ◽  
Konstantin Evdokimov ◽  
Pisey Tan ◽  
Phana Leab ◽  
...  

Abstract Background The rising incidence of infections caused by MDR organisms (MDROs) poses a significant public health threat. However, little has been reported regarding community MDRO carriage in low- and middle-income countries. Methods We conducted a cross-sectional study in Siem Reap, Cambodia comparing hospital-associated households, in which an index child (age: 2–14 years) had been hospitalized for at least 48 h in the preceding 2–4 weeks, with matched community households on the same street, in which no other child had a recent history of hospitalization. Participants were interviewed using a survey questionnaire and tested for carriage of MRSA, ESBL-producing Enterobacterales (ESBL-E) and carbapenemase-producing Enterobacterales (CPE) by culture followed by antibiotic susceptibility testing. We used logistic regression analysis to analyse associations between collected variables and MDRO carriage. Results Forty-two pairs of households including 376 participants with 376 nasal swabs and 290 stool specimens were included in final analysis. MRSA was isolated from 26 specimens (6.9%). ESBL-producing Escherichia coli was detected in 269 specimens (92.8%) whereas ESBL-producing Klebsiella pneumoniae was isolated from 128 specimens (44.1%), of which 123 (42.4%) were co-colonized with ESBL-producing E. coli. Six (2.1%) specimens tested positive for CPE (4 E. coli and 2 K. pneumoniae). The prevalence ratios for MRSA, ESBL-producing E. coli and ESBL-producing K. pneumoniae carriage did not differ significantly in hospital-associated households and hospitalized children compared with their counterparts. Conclusions The high prevalence of ESBL-E across both household types suggests that MDRO reservoirs are common in the community. Ongoing genomic analyses will help to understand the epidemiology and course of MDRO spread.


2021 ◽  
Author(s):  
Wei Tu ◽  
Yu-Ye Li ◽  
Yi-Qun Kuang ◽  
Rong-Hui Xie ◽  
Xing-Qi Dong ◽  
...  

Abstract Background Yunnan has the highest rates of HIV in the country. Other treatable sexually transmitted infections (STIs) are associated with accelerated HIV transmission and poor ART outcomes, but are only diagnosed by syndromic algorithms. Methods We recruited 406 HIV-positive participants for a cross-sectional study (204 ART-naive and 202 ART). Blood samples and first-voided urine samples were collected. Real-time polymerase chain reaction methods were used for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Mycoplasma genitalium (MG). Syphilis and HSV-2 tests were also performed. Results Among 406 participants, the overall prevalence of STI was 47.0% and 45.1% in ART-naive individuals and 49.0% in ART individuals, respectively. Testing frequency was 11.6% (11.8% vs 11.4%), 33.2% (29.4% vs 37.1%), 3.2% (3.4% vs 3.0%), 2.0% (3.4% vs 0.5%) and 4.7% (6.4% vs 3.0%) for active syphilis, HSV-2, chlamydia, gonorrhoeae and genitalium. Percentage of multiple infections in both groups was 10.8% (22/204) in ART-naive participants and 9.9% (20/202) in ART participants. Females, age between 18 to 35 years, ever injected drugs, homosexual or bisexual, HIV/HBV coinfection, and not receiving ART were identified as risk factors. Self-reported asymptom was not eliminating of having a laboratory-diagnosed STI. Conclusions STI prevalence was 47.0% (45.1% vs 49.0%), HSV-2, syphilis and MG were the most common STIs in HIV-infected individuals. We found high prevalence (6.4%) of Mycoplasma genitalium in ART-naive individuals. ART can reduce the diversity of STI-HIV coinfection but not the prevalence. HIV-positive individuals tend to neglect or maybe hide their genital tract discomfort, thus we suggest strengthening STI joint screening and treatment services among HIV-infected individuals whether they describe genital tract discomfort or not.


Author(s):  
Seema B. N.

Background: Anemia is the nutritional deficiency disorder and 56% of all women living in developing countries are anaemic according to World Health Organization. India has the highest prevalence of anaemia and 20% of total maternal deaths are due to anemia. To determine the prevalence of anemia and factors influencing its causation among pregnant women.           Methods: This is the study of 1769 pregnant women which was conducted in a rural population of Koppal district, Karnataka, India, from June 2016 to November 2016 i.e. a period of 6 months. This longitudinal prospective observational study was conducted in the district hospital of Koppal. Anemia was classified as per the Indian Council of Medical Research (ICMR) criteria. The diagnosis of anemia was undertaken by peripheral blood smear examination and standard hemoglobin estimation by shale’s method.Results: The average age of pregnant women was 23.5 years, ranging between 18 and 40 years. Most of the women belonged to below poverty line (BPL) families (84.6%) and Hindu religion (98%). Regarding education, 28.9% were illiterates. The mean haemoglobin level was found to be 8.95. Prevalence of anemia was 96.5% among the pregnant females in this region of rural Koppal. Out of these 22.47% had mild anemia, 56.30% had moderate anemia, 14.98% had severe anemia and 2.73% very severe anemia according to ICMR classification of anemia.Conclusions: High prevalence of anemia among pregnant women indicates anemia to be a major public health problem in the rural community and indicates strict implementation of National Nutrition Anemia prophylaxis programme. Factors such as socioeconomic status, education, birth interval, and gravida contribute to this high prevalence.


Author(s):  
Drpadmajauday Kumar ◽  
Varsha Kalyanpur

ABSTRACTObjectives: Estimating the hemoglobin (Hb) status in female medicos through prospective cross-sectional study and assessment of influencing ofcofactors were objectives.Methods: Women medicos who volunteered, consented and met selection criteria were enrolled. Hb level was estimated to diagnose anemia.Relationship with influencing factors was assessed statistically.Result: A total of 100 eligible students were enrolled. Mean age±standard deviation (SD) age of the participants’ was 20.9±3.1 years (17-25 years).Mean±SD Hb was 12.25±1.0189 g% (9.0-16.0 g%). 33 were anemic, and mild anemia (32%) was frequent. There was a history of worm infestation inthree students (3%), who were treated adequately. Nine were on iron supplements of which five were still anemic and were continuing the treatmentby the end of the study. 28 (84.84%) anemic students were not on any iron or hematinic treatment. There was no association between the anemiaand nature of diet, consumption of green leafy vegetables, consumption of coffee/tea after food, smoking/tobacco or alcohol consumption, mother’seducation, socioeconomic status, menstrual factors, and physical exercise. The prevalence of anemia was found to be higher in underweight andoverweight students in comparison to students with normal body mass index.Asymptomatic participants (n=78) outnumbered symptomatic ones(n=22), but without any statistical significance. Easy fatigability (14%), pallor (7%), breathlessness (6%), weakness (9%), and easy bruising (1%)were frequent complaints.Conclusion: Anemia is frequent among women medicos, often underdiagnosed, under-reported, many remaining asymptomatic. Negligence ofmedical students toward their anemic status despite the awareness of consequences of low Hb level is a serious cause of concern.Keywords: Awareness, Hemoglobin, Nutritional anemia, Women medical students.


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