Immune thrombocytopenia in a newborn – a clinical case in pediatrics

Annotation. The aim of the study was to analyze with the help of literature data the features of the clinical course of immune thrombocytopenia, to monitor the mechanisms of reactions, as well as to reproduce them on their own observation. Features of clinical course and differential diagnosis of immune thrombocytopenia are described. It is established that the main manifestation of this pathology is hemorrhagic syndrome, accompanied by skin hemorrhages, bleeding, possible hepatosplenomegaly, jaundice. Detection of antiplatelet antibodies is used to confirm the diagnosis.

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Clinical case in outpatient practice: acute tonsillitis against background of COVID-19

Medical alphabet ◽

10.33667/2078-5631-2021-11-34-39 ◽

2021 ◽

Vol 1 (11) ◽

pp. 34-39

Author(s):

N. V. Orlova ◽

V. V. Lomaychikov

Keyword(s):

Differential Diagnosis ◽

Antibacterial Therapy ◽

Clinical Case ◽

Clinical Symptoms ◽

Clinical Course ◽

Review Of The Literature ◽

Acute Tonsillitis ◽

The Past ◽

Severe Intoxication ◽

Outpatient Practice

Over the past period of the COVID‑19 pandemic, experience has been gained on the ways of spreading the infection, new approaches to treatment have been formed, and preparations for vaccine prevention have been created. Information about COVID‑19 is updated with new data on the features of the clinical course, including rare manifestations of the disease. The clinical symptoms of CAVID‑19 are characterized by a significant variety and are due to the tropism of the SARS‑CoV‑2 virus to various tissues. The article describes a clinical case of COVID‑19. With severe intoxication syndrome, the patient was found to have concomitant acute tonsillitis. The article provides a review of the literature on the clinical symptoms of COVIND‑19 and the mechanisms of their development. The differential diagnosis of viral and bacterial tonsillitis is considered. Efficacy of antibacterial therapy of tonsillitis with cefixime. The clinical case is illustrated with photos.

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HELLP SYNDROME: FEATURES OF THE CURRENT

Medical Journal ◽

10.51922/1818-426x.2021.3.131 ◽

2021 ◽

pp. 131-135

Author(s):

L.F. Mozheiko ◽

◽

К.L. Sushch ◽

Е.V. Fedotova ◽

S.М. Stasevich ◽

...

Keyword(s):

Health Care ◽

Differential Diagnosis ◽

Hellp Syndrome ◽

Clinical Case ◽

Clinical Laboratory ◽

Clinical Course ◽

Pregnancy Complication ◽

Early Postpartum Period ◽

Early Postpartum ◽

Pathogenetic Therapy

The article describes a clinical case of HELLP-syndrome in the early postpartum period. The relevance of the presented case determines by the complexity of differential diagnosis and the high risk of complications. HELLP-syndrome establishes on the basis of the results of clinical, laboratory and instrumental studies after surgical delivery in an emergency. The article describes the features of the clinical course, the results of laboratory and instrumental studies against the background of therapy in the conditions of the resuscitation-anesthesiology and observation departments of the health care institution "Minsk City Clinical Hospital № 1". The importance of timely diagnosis of the presented pregnancy complication with early pathogenetic therapy, rapid and careful delivery of such women is noted.

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Clinical case: Complicated differential diagnosis between postsurgical and functional hypoparathyroidism.

Endocrine Abstracts ◽

10.1530/endoabs.70.ep74 ◽

2020 ◽

Author(s):

Elena Kovaleva ◽

Anna Eremkina ◽

Julia Krupinova ◽

Natalia Mokrysheva

Keyword(s):

Differential Diagnosis ◽

Clinical Case

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Acute Disseminated Encephalomyelitis (ADEM): A Demyelinating Disease with Specific Morphological Features

International Journal of Surgical Pathology ◽

10.1177/1066896921993562 ◽

2021 ◽

pp. 106689692199356

Author(s):

Fleur Cordier ◽

Lars Velthof ◽

David Creytens ◽

Jo Van Dorpe

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Differential Diagnosis ◽

Clinical Case ◽

Demyelinating Disease ◽

Acute Disseminated Encephalomyelitis ◽

Demyelinating Diseases ◽

Demyelinating Disorder ◽

Immune Mediated ◽

The Central Nervous System

Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated inflammatory and demyelinating disorder of the central nervous system. Its characteristic perivenular demyelination and inflammation aid in the differential diagnosis with other inflammatory demyelinating diseases. Here, we present a clinical case of ADEM, summarize its histological hallmarks, and discuss pitfalls concerning the most important neuropathological differential diagnoses.

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Lipschütz Ulcer: An Unusual Diagnosis that Should Not be Neglected

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0041-1729147 ◽

2021 ◽

Vol 43 (05) ◽

pp. 414-416

Author(s):

Daniela Alexandra Gonçalves Pereira ◽

Eliana Patrícia Pereira Teixeira ◽

Ana Cláudia Martins Lopes ◽

Ricardo José Pina Sarmento ◽

Ana Paula Calado Lopes

Keyword(s):

Emergency Department ◽

Differential Diagnosis ◽

Clinical Course ◽

Malignant Tumors ◽

Sudden Onset ◽

Drug Reactions ◽

Genital Ulceration ◽

Sexually Transmitted ◽

Inflammatory Processes ◽

Genital Ulcers

AbstractThe diagnosis of genital ulcers remains a challenge in clinical practice. Lipschütz ulcer is a non-sexually transmitted rare and, probably, underdiagnosed condition, characterized by the sudden onset of vulvar edema along with painful necrotic ulcerations. Despite its unknown incidence, this seems to be an uncommon entity, with sparse cases reported in the literature. We report the case of an 11-year-old girl who presented at the emergency department with vulvar ulcers. She denied any sexual intercourse. The investigation excluded sexually transmitted infections, so, knowledge of different etiologies of non-venereal ulcers became essential. The differential diagnoses are extensive and include inflammatory processes, drug reactions, trauma, and malignant tumors. Lipschütz ulcer is a diagnosis of exclusion. With the presentation of this case report, the authors aim to describe the etiology, clinical course, and outcomes of this rare disease, to allow differential diagnosis of genital ulceration.

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Congenital optic disc coloboma

Russian ophthalmology of children ◽

10.25276/2307-6658-2021-1-33-39 ◽

2021 ◽

pp. 33-39

Author(s):

A.O. Nazarenko ◽

◽

E.E. Sidorenko ◽

D.V. Miguel ◽

A.S. Smartsev ◽

...

Keyword(s):

Differential Diagnosis ◽

Optic Nerve ◽

Clinical Picture ◽

Clinical Case ◽

Charge Syndrome ◽

Diagnostic Methods ◽

Newly Diagnosed ◽

Optic Nerve Atrophy ◽

Optic Disc Coloboma ◽

Optic Nerve Coloboma

A clinical case of observation of a 3-year-old child with a newly diagnosed optic nerve coloboma and multiple malformations is considered. The clinical picture and diagnostic methods necessary for the diagnosis are reflected. On the example of this child, the differential diagnosis with Charge syndrome is considered. Key words: coloboma, optic nerve coloboma, partial optic nerve atrophy, astigmatism, Charge syndrome.

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Clinical case of recurrent vomiting in a child: diagnostic search from functional gastrointestinal disorders to piloid astrocytoma

Practical medicine ◽

10.32000/2072-1757-2021-1-78-81 ◽

2021 ◽

Vol 19 (1) ◽

pp. 78-81

Author(s):

E. N. Voronina ◽

◽

D. V. Pechkurov ◽

A. A. Tyazheva ◽

E. V. Kozarez ◽

...

Keyword(s):

Differential Diagnosis ◽

Nutritional Status ◽

Clinical Case ◽

Anxiety Symptom ◽

Functional Gastrointestinal Disorders ◽

Integrated Approach ◽

Gastrointestinal Disorders ◽

Wide Range ◽

High Prevalence ◽

Recurrent Vomiting

The urgency of the problem of recurrent vomiting in children is due not only to the high prevalence of this syndrome, but also to a wide range of reasons for its development. The article presents a clinical case of observation of a child with recurrent vomiting syndrome. It shows the dynamics of the disease, the importance of identifying such «anxiety symptom» as the nutritional status violation. In this case, the cause of vomiting of central genesis was not immediately taken into account, although differential diagnosis presupposes an integrated approach, and doctors' oncological alertness should be constantly preserved even in pediatrics.

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Bilateral Charcot hip Arthropathy Due to Tabes Dorsalis: A Case Report

Journal of Orthopaedics Trauma and Rehabilitation ◽

10.1016/j.jotr.2017.08.003 ◽

2018 ◽

Vol 25 (1) ◽

pp. 21-23

Author(s):

Ip Hoi Yeung ◽

Yeung Yip Kan ◽

Luk Kristine Shik ◽

Lam Polly Wy ◽

Wong Kwok Ho

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Clinical Course ◽

High Index ◽

Tabes Dorsalis ◽

High Index Of Suspicion

This article illustrates the clinical course of a patient diagnosed to have bilateral Charcot hip arthropathy secondary to tabes dorsalis from delayed untreated syphilitic infection. This differential diagnosis of rapid bilateral hip destruction was a near-extinct entity, and a high index of suspicion is needed to prevent untoward sequelae.

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