scholarly journals URINARY SYSTEM PATHOLOGY IN CHILDREN POPULATION OF KHARKIV REGION: MORBIDITY AND SOME RISK FACTORS

2015 ◽  
pp. 21-26
Author(s):  
G. R. Muratov ◽  
T. F. Kolibaeva ◽  
I. V. Sorokina ◽  
M. S. Myroshnychenko
Keyword(s):  
Risk Factors ◽  
Clinical Diagnosis ◽  
Body Length ◽  
Gestational Age ◽  
Congenital Malformations ◽  
Medical Science ◽  
Urinary System ◽  
System A ◽  
The Village ◽  
All Diseases

Urinary system pathology in children now is one of the most important problems of medical science. The aim of this study – to analyze the morbidity and reveal the risk factors for development of urinary system diseases in children of Kharkiv region. Materials and methods. The material of the study was the information (gender, age, weight and body length at birth, gestational age, clinical diagnosis), obtained during hospitalization of 663 patients aged from 3 months to 17 years in the nephrological center of Kharkiv regional children clinical hospital during the period from 2012 to 2013 years. Results. The authors found that in children population of Kharkiv region among all diseases of urinary system a significant number of cases occur in congenital malformations, dismetabolic nephropathy, urolithiasis. Conclusions. Regional risk factors for development of urinary system pathology in children are female and living in the village. Decreased weight and body length at birth are risk factors for development in children urinary system congenital malformations.

scholarly journals Сhronic kidney disease in children: principles of ambulatory management

2021 ◽  
Vol 24 (2) ◽  
pp. 122-129
Author(s):  
Albina A. Vyalkova ◽  
Svetlana A. Chesnokova ◽  
Oksana O. Ustinova ◽  
Larisa A. Gaikova
Keyword(s):  
Risk Factors ◽  
Kidney Disease ◽  
Early Diagnosis ◽  
Congenital Malformations ◽  
Urinary System ◽  
Renal Lesions ◽  
Primary Health ◽  
Uremic Syndrome ◽  
Renal Infection ◽  
Hereditary Nephropathies

Introduction. The term «chronic kidney disease» (CKD) is used to define the outcomes of various forms of chronic progressive kidney disease, characterized by kidney damage, or a decrease in their function for three months or more, regardless of the nosological diagnosis. The aim of the work was to determine the frequency, structure, and clinical and paraclinical features of CKD in children to substantiate the principles of its management in primary health care. Results. In CKD patients, tubulointerstitial renal lesions were established to prevail (80%). Associated with congenital malformations of the urinary system, reflux uropathy, and urolithiasis in 98% of cases tubulointerstitial renal lesions are complicated by renal infection. In 8.9% of children, CKD was formed as an outcome of glomerulopathies; in 6.7% of children - with congenital and hereditary nephropathies; in 4.4% of children an outcome of a hemolytic uremic syndrome. The observed children dominated by I-II (74.3%), less often III and IV (25.7%) stages of CKD. The revealed clinical and paraclinical features of CKD in children are presented. The modern principles of early diagnosis of CKD in children and the identification of risk factors for the progression of nephropathy have been substantiated. For the diagnosis of CKD in childhood there has been created a. n algorithm, including at the outpatient stage. Authors suggested a set of measures for the prevention of nephropathy. Conclusion. For early diagnosis of CKD in childhood there was developed an algorithm based on the analysis of a complex of clinical and paraclinical, structural and functional parameters of the kidneys in combination with the parameters of endothelial function and cytokine status.

scholarly journals “Clinical masks” of congenital malformations of urinary system in children of early age

2021 ◽  
Vol 5 (3) ◽  
pp. 244-251
Author(s):  
Nataliia S. Lukyanenko ◽  
Danara M. Imanmadiyeva ◽  
Vilena T. Dolinnaya ◽  
Anastasiya Spaska
Keyword(s):  
Early Childhood ◽  
Young Children ◽  
Clinical Diagnosis ◽  
Acute Pyelonephritis ◽  
Congenital Malformations ◽  
Social Effects ◽  
Hospital Treatment ◽  
Early Age ◽  
Urinary System ◽  
Childhood Morbidity

Nowadays there is an increase in nephropathy in young children, which is associated not only with environmental impacts, but also with an increase in the incidence of congenital and hereditary caused forms of diseases, an increase in the incidence of mothers, and an improvement in diagnosis. In order to analyze the frequency of congenital malformations of the urinary system in young children under the “clinical masks” of various somatic pathologies, 864 cards of inpatients that were treated in the Early Childhood Department of the Regional Children's Clinical Hospital “OKHMATDYT” during 2013 were analyzed. The authors came to the conclusion that congenital malformations of the urinary system in young children are a frequent pathology, diagnosed in 44.6% of children admitted to the To the Department of the early age for acute pyelonephritis to get 10.3% of all children who were admitted to hospital treatment. The introduction of a two-stage algorithm for the diagnosis of congenital malformations of the urinary system allows us to recognize their various “clinical masks” and timely establish a clinical diagnosis of anomalies. This approach makes it possible to conduct adequate therapy and reduce high rates of childhood morbidity and disability, and has significant medical and social effects.

Left Ventricular Hypertrophy

2014 ◽  
Vol 19 (2) ◽  
pp. 11-15
Author(s):  
Steven L. Demeter
Keyword(s):  
Risk Factors ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Mass Index ◽  
Medical Science ◽  
Careful Analysis ◽  
Left Ventricular ◽  
Hypertensive Disease ◽  
Accurate Analysis ◽  
Clear Explanation

Abstract The fourth, fifth, and sixth editions of the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides) use left ventricular hypertrophy (LVH) as a variable to determine impairment caused by hypertensive disease. The issue of LVH, as assessed echocardiographically, is a prime example of medical science being at odds with legal jurisprudence. Some legislatures have allowed any cause of LVH in a hypertensive individual to be an allowed manifestation of hypertensive changes. This situation has arisen because a physician can never say that no component of LVH was not caused by the hypertension, even in an individual with a cardiomyopathy or valvular disorder. This article recommends that evaluators consider three points: if the cause of the LVH is hypertension, is the examinee at maximum medical improvement; is the LVH caused by hypertension or another factor; and, if apportionment is allowed, then a careful analysis of the risk factors for other disorders associated with LVH is necessary. The left ventricular mass index should be present in the echocardiogram report and can guide the interpretation of the alleged LVH; if not present, it should be requested because it facilitates a more accurate analysis. Further, if the cause of the LVH is more likely independent of the hypertension, then careful reasoning and an explanation should be included in the impairment report. If hypertension is only a partial cause, a reasoned analysis and clear explanation of the apportionment are required.

Acute kidney injury in preterm neonates with ≤30 weeks of gestational age and its risk factors

2019 ◽  
Vol 71 (5) ◽  
Author(s):  
Rita Ladeiras ◽  
Filipa Flor-De-Lima ◽  
Henrique Soares ◽  
Bárbara Oliveira ◽  
Hercília Guimarães
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Gestational Age ◽  
Kidney Injury ◽  
Preterm Neonates

RISK FACTORS FOR SMALL FOR GESTATIONAL AGE INFANTS: A STUDY BASED ON THE ARKHANGELSK COUNTY BIRTH REGISTRY

2020 ◽  
Vol 99 (1) ◽  
pp. 32-39
Author(s):  
A.A. Usynina ◽  
◽  
G.N. Chumakova ◽  
V.A. Postoev ◽  
J.O. Odland ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Birth Registry

Prevention of Preterm Birth

2018 ◽  
Vol 11 (2) ◽  
pp. 95-104
Author(s):  
Ivan D. Ivanov ◽  
Stefan A. Buzalov ◽  
Nadezhda H. Hinkova
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
High Risk ◽  
Medical Science ◽  
Secondary Prophylaxis ◽  
High Risk Group ◽  
Screening Methods ◽  
Perinatal Complications ◽  
Social Significance ◽  
Neonatal Deaths

Summary Preterm birth (PTB) is a worldwide problem with great social significance because it is a leading cause of perinatal complications and perinatal mortality. PTB is responsible for more than a half of neonatal deaths. The rate of preterm delivery varies between 5-18% worldwide and has not decreased in recent years, regardless of the development of medical science. One of the leading causes for that is the failure to identify the high-risk group in prenatal care. PTB is a heterogeneous syndrome in which many different factors interfere at different levels of the pathogenesis of the initiation of delivery, finally resulting in delivery before 37 weeks of gestation (wg). The various specificities of risk factors and the unclear mechanism of initiation of labour make it difficult to elaborate standard, unified and effective screening to diagnose pregnant women at high-risk for PTB correctly. Furthermore, they make primary and secondary prophylaxis less effective and render diagnostic and therapeutic measures ineffective and inappropriate. Reliable and accessible screening methods are necessary for antenatal care, and risk factors for PTB should be studied and clarified in search of useful tools to solve issues of risk pregnancies to decrease PTB rates and associated complications.

NATRIURETIC PEPTIDES LEVEL AND THE STATUS OF THE RENIN – ANGIOTENSIN-ALDOSTERONE SYSTEM IN CHRONIC KIDNEY DISEASE IN PATIENTS WITH CONGENITAL MALFORMATIONS OF THE URINARY SYSTEM

2018 ◽  
Vol 22 (5) ◽  
pp. 45-50
Author(s):  
A. M. Mambetova ◽  
A. M. Inarokova ◽  
N. N. Shabalova ◽  
D. V. Bizheva ◽  
A. T. Mahiyeva
Keyword(s):  
Congenital Malformations ◽  
Control Group ◽  
Healthy Children ◽  
Urinary System ◽  
Renin Angiotensin Aldosterone System ◽  
Natriuretic Hormone ◽  
Renin Angiotensin ◽  
Group I ◽  
The Status ◽  
Sick Children

THE AIM. To determine the concentration of natriuretic peptide in the blood serum in children with congenital malformations of the urinary system (CM US) and to compare with the activity of renin-angiotensin-aldosterone system (RAAS).MATERIALS AND METHODS.119 patients with CM US aged 3 to 18 years were examined. A control group of 10 clinically healthy children. 3 groups were assigned: group I – 55 children with  congenital vesicoureteral reflux, and group II – 34 children with  congenital hydronephrosis and ureterohydronephrosis, III group – 30 children with other forms of dysembryogenesis of the US. Following indicators were identified by ELISA in the blood: renin, aldosterone,  N – terminal propeptide natriuretic hormone (NT-рroВNР). RESULTS.NT-рroВNР, renin and aldosterone hyperproduction were diagnosed in 59,6%, 69,7%, 54.6 % of sick children relatively. Concentrations were higher in all variants of  malformations in comparison with the control group. Significant  differences were revealed in obstructive species, where arterial  hypertension (AH) was diagnosed more often. Patients with AH  recorded significantly higher concentrations of NT-proВNР and renin.CONCLUSION.The key point in pathological processes developmentand progression in the cardiovascular system and kidneys is the  activation of RAAS. The system of natriuretic factors is important in maintaining the compensated state of patients due to the blockade of RAAS.

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