scholarly journals Factors Associated with Mortality in Patients with Gastric Cancer at a Reference Hospital

2019 ◽  
Vol 4 (3) ◽  
pp. 65-70
Author(s):  
Francisca Bruna Arruda Aragão ◽  
Gerusinete Rodrigues Bastos dos Santos ◽  
Gabrielle Vieira Da Silva Brasil ◽  
Bruno Carvalho Campelo ◽  
Ana Patrícia Fonseca Coelho Galvão ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Alcohol Consumption ◽  
Cancer Staging ◽  
Metropolitan Region ◽  
Mortality Factors ◽  
Factors Associated ◽  
Kaplan Meier ◽  
Reference Hospital ◽  
Epidemiological Profile

Background: Gastric cancer (GC) is the second cause of death by tumor in the world. In Brazil, the survival rate of patients with GC is only five years, due to the low rates of early diagnosis, with about 10 to 15% of the cases. Thus, this study aims to evaluate the factors associated with mortality in CG patients treated at a reference hospital. Method: The study was carried out based on the survey of 96 medical records of patients diagnosed with GC, whose analyzed data were: sex, age, educational level, occupation (socioeconomic level), and risk factors, such as smoking, alcohol consumption, family history of cancer, staging and type of treatment adopted, among other variables. Statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS-PC) and Kaplan-Meier for survival analysis. Absolute and relative frequencies were calculated for all variables. Results: The sample consisted mainly of male patients with stable union, brown-colored, who lived in the metropolitan region and presented low schooling. In addition, risk factors such as smoking and alcoholism presented a high prevalence in the sample. Regarding mortality, factors such as arterial hypertension (p = 0.1581), diabetes (p = 0.3212), and alcohol consumption (p = 0.6704) were not associated with increased mortality in this study.Conclusion: The clinical and epidemiological profile of patients with GC presented a low degree of tumor differentiation, with predominance of the mixed or unclassifiable subtype. In addition, the majority of the sample was composed of patients living in the metropolitan region and the main form of treatment adopted was surgical intervention in combination with chemotherapy.

scholarly journals Risk factors associated with the severity of COVID-19 in a region of the Brazilian Amazon

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Daniele Melo Sardinha ◽  
Rosane do Socorro Pompeu de Loiola ◽  
Ana Lúcia da Silva Ferreira ◽  
Carmem Aliandra Freire de Sá ◽  
Yan Corrêa Rodrigues ◽  
...  
Keyword(s):  
Risk Factors ◽  
Brazilian Amazon ◽  
The State ◽  
Metropolitan Region ◽  
Epidemiological Surveillance ◽  
Cross Sectional ◽  
Factors Associated ◽  
Risk Of Death ◽  
Increased Risk ◽  
Brazilian Amazon Region

AbstractThe Brazilian Northern region registered a high incidence of COVID-19 cases, particularly in the state of Pará. The present study investigated the risk factors associated with the severity of COVID-19 in a Brazilian Amazon region of 100,819 cases. An epidemiological, cross-sectional, analytical and demographic study, analyzing data on confirmed cases for COVID-19 available at the Brazilian Ministry of Health's surveillance platform, was conducted. Variables such as, municipalities of residence, age, gender, signs and symptoms, comorbidities were included and associated with COVID-19 cases and outcomes. The spatial distribution was performed using the ArcGIS program. A total of 100,819 cases were evaluated. Overall, patients had the mean age of 42.3 years, were female (51.2%) and with lethality reaching 4.79% of cases. Main symptoms included fever (66.5%), cough (61.9%) and sore throat (39.8%). Regarding comorbidities, most of the patients presented cardiovascular disease (5.1%) and diabetes (4.2%). Neurological disease increased risk of death by nearly 15 times, followed by obesity (5.16 times) and immunodeficiency (5.09 time). The municipalities with the highest incidence rate were Parauapebas, Canaã dos Carajás and Jacareacanga. Similarity between the Lower Amazon, Marajó and Southwest mesoregions of Pará state were observed concerning the highest morbidity rates. The obtained data demonstrated that the majority of cases occurred among young adults, females, with the classic influenza symptoms and chronic diseases. Finally, data suggest that the highest incidences were no longer in the metropolitan region of the state. The higher lethality rate than in Brazil may be associated with the greater impacts of the disease in this Amazonian population, or factors associated with fragile epidemiological surveillance in the notification of cases of cure.

scholarly journals Risk factors associated with the development of gastric cancer — case-control study

2018 ◽  
Vol 64 (7) ◽  
pp. 611-619 ◽  
Author(s):  
Marcus Fernando Kodama Pertille Ramos ◽  
Ulysses Ribeiro Júnior ◽  
Juliana Kodaira Yukari Viscondi ◽  
Bruno Zilberstein ◽  
Ivan Cecconello ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Cancer Case ◽  
Gastric Cancer Case ◽  
Factors Associated ◽  
Control Study ◽  
Development Of Gastric Cancer

scholarly journals Factors Associated with Violent Behavior among Adolescents in Northeastern Brazil

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Roberto Jerônimo dos Santos Silva ◽  
Nara Michelle Moura Soares ◽  
Antônio César Cabral de Oliveira
Keyword(s):  
Alcohol Consumption ◽  
Violent Behavior ◽  
Descriptive Statistics ◽  
Northeastern Brazil ◽  
Alcoholic Beverages ◽  
Metropolitan Region ◽  
Male And Female ◽  
Public Network ◽  
Factors Associated ◽  
Behavioral Variables

The aim of this study was to identify prevalence and factors associated with violent behavior among adolescents in Aracaju and Metropolitan region. The study included 2207 adolescents (16.03 ± 1.08 years old) enrolled in high schools of the State Public Network. Violent behavior was identified from question 14 of the YRBS-2007 questionnaire with responses categorized as “never” and “one or more times.” Higher prevalence in males in relation to risk factors for adoption of violent behavior was found: cigarette consumption (7.3%), alcohol consumption (39.1%), and marijuana use (3.4%). Data analysis used descriptive statistics and logistic regression with hierarchical model at two levels: (a) sociodemographic variables and (b) behavioral variables. For both sexes, association between violent behavior and cigarette smoking (OR = 3.77, CI 95% = 2.06–6.92 and OR = 1.99, CI 95% = 1.04 to 3.81, male and female, resp.) and alcohol consumption (OR = 3.38, CI 95% = 2.22 to 5.16 and OR = 1.83, CI 95% = 1.28 to 2.63, male and female, resp.) was verified. It was concluded that violent behavior is associated with the consumption of alcoholic beverages and cigarettes among adolescents.

scholarly journals Preoperative Anemia and Thrombocytosis Predict Adverse Prognosis in Non-Metastatic Renal Cell Carcinoma With Tumor Thrombus

2020 ◽  
Author(s):  
Lulin Ma ◽  
Xiao Ruotao ◽  
Xu Chuxiao ◽  
He Wei ◽  
Liu Lei ◽  
...  
Keyword(s):  
Risk Factors ◽  
Renal Cell Carcinoma ◽  
Prognostic Factors ◽  
Tumor Thrombus ◽  
Preoperative Anemia ◽  
Factors Associated ◽  
Node Metastasis ◽  
Kaplan Meier ◽  
Metastatic Rcc ◽  
Grade Iii

Abstract Objection: The aim of the study was to determine the prognostic value of preoperative blood parameters in patients with renal cell carcinoma (RCC) and tumor thrombus (TT) treated surgically.Method: we retrospectively analyzed 152 patients diagnosis with RCC and TT and treated surgically. Clinicopathologic data and blood parameter were obtained. Univariable and multivariable analysis using the Cox regression model were performed to determine risk factors that were associated with progression-free survival (PFS) and overall survival (OS). Kaplan-Meier curve and logistic regression were performed to analyze the risk factors.Results: Preoperative Hgb＜120g/L (HR=2.48, P=0.024) and lymph node metastasis (HR=3.98, P=0.032) were an independent prognostic factors associated with OS. Preoperative PLT≥300×109/L (HR=2.10, P=0.014) and lymph node metastasis (HR=3.42, P=0.021) were an independent prognostic factors associated with PFS. In Kaplan–Meier survival analysis, preoperative anemia had worse OS than without anemia (P=0.003) and thrombocytosis had worse PFS than without thrombocytosis (P=0.001). Preoperative anemia were associated with more symptomatic (P=0.009), surgical time≥6h (P=0.016), Blood loss≥1000ml (P=0.014), transfusion(P=0.012), higher thrombus level (III-IV) (P=0.004) and higher nuclear grade (III-IV) (P=0.002) while thrombocytosis were associated with more symptomatic (P=0.008) and higher nuclear grade (III-IV) (P=0.042)Conclusions: Preoperative anemia and thrombocytosis was associated with adverse prognosis in patients with non-metastatic RCC with TT. Both preoperative hemoglobin level and platelet count may be clinical useful for risk stratifying patients receiving operation for non-metastatic RCC with TT.

scholarly journals CLINICO-EPIDEMIOLOGICAL PROFILE AND RISK FACTORS ASSOCIATED WITH FAILURE OF CONSERVATIVE THERAPY IN PEDIATRIC EMPYEMA PATIENTS

2018 ◽  
Vol 05 (08) ◽  
pp. 545-548
Author(s):  
Vipul Gautam ◽  
Ajay Kumar ◽  
Balvinder Singh Arora ◽  
Shyam Sunder Mina ◽  
Kailash Chandra Aggarwal
Keyword(s):  
Risk Factors ◽  
Conservative Therapy ◽  
Factors Associated ◽  
Epidemiological Profile

scholarly journals Behavioural Risk Factors Associated With Prostate Cancer: The Prostate Cancer Transatlantic Consortium (CaPTC) Cohort Study

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 5s-5s
Author(s):  
C.A. Oladoyinbo ◽  
O.O. Akinbule ◽  
A.A. Sobo ◽  
O.O. Bolajoko ◽  
I.E. Bassey ◽  
...  
Keyword(s):  
Physical Activity ◽  
Prostate Cancer ◽  
Risk Factors ◽  
Alcohol Consumption ◽  
West African ◽  
Activity Level ◽  
Factors Associated ◽  
The Usa ◽  
History Of ◽  
The Mean

Background: Studies have linked genetic susceptibility to prostate cancer (CaP) to African heritage and familial disease. Also, lifestyle factors, general and central obesity have been identified as risk factors for CaP. Aim: To assess the behavioral risk factors associated with CaP among West-African men and US West African immigrants. Methods: The cross-sectional study was conducted among 480 respondents recruited from Nigeria, Cameroon and the United States. The CaPTC Familial Project study instrument was used to collect data on the background information of respondents, country specific residence information, physical activity level, smoking and alcohol consumption pattern, family and personal history of cancer and other types of cancers and knowledge of CaP. Anthropometric measurements were taken. Data were analyzed using SPSS version 20. Results: Majority (85.6%) were recruited from Nigeria, 5.5% from Cameroon and 8.9% from the USA and the mean age is 48.2±9.9. About three quarters (74.4%) have been married only once while 10.8% have been married for about 2-5 times. Few (3.3%) of the respondent's wives had cancer and 0.2% had cervical cancer. Less than 1% of respondent's daughters had cancer, 4.6% of their uncles had cancer. Among the respondent's full brothers and sisters, 0.4% had cancer and 1.5% of their birth mothers had cancer. Also a few (2.3%) of respondent's fathers had cancer and 11.9% of their paternal grandparents had one type of cancer. About 17.2% of respondents have been diagnosed of a prostate condition and 5.9% were diagnosed of CaP with 47.1% of those with CaP are from Nigeria, 49.6% from the USA and 3.3% from Cameroon. One-quarter (25.6%) have smoked at least once in their lifetime, 2.5% smoke daily and the mean age at which smoking commenced is 26.6±19.4. More than half (55.4%) had consumed alcohol at least once in their lifetime and the mean age at which alcohol consumption started is 9.9±11.9. Only 9.8% had adequate knowledge about CaP and 61.0% poor knowledge. About a quarter (25.5%) were obese with 3.3% being morbidly obese. One-third (32.3%) are involved in moderate physical activity and 17.9% in rigorous physical activity. No significant difference ( P = 0.492) was observed in the physical activity level from the different locations. However, a significant relationship was observed between alcohol consumption, smoking, body mass index and country of residence ( P = 0.001, 0.035 and 0.001 respectively). Cigarette smoking and alcohol consumption (frequency and quantity) was significantly higher among respondents from the USA. Obesity was also significantly higher among the respondents from Nigeria and the USA. Although not statistically significant, family history of cancer was more among respondents from Nigeria and the USA. Conclusion: Obesity, smoking, alcohol consumption seems to be a common practice among respondents from Nigeria and USA.

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