scholarly journals PECULIARITIES OF ONYCHOMYCOSIS COURSE AND TREATMENT AT PRESENT

2021 ◽  
Vol 21 (3) ◽  
pp. 274-279
Author(s):  
K.G. Suprun
Keyword(s):  
Scientific Literature ◽  
Clinical Manifestations ◽  
Significant Risk ◽  
Pathological Process ◽  
Current Data ◽  
Epidemiological Features ◽  
Age Related ◽  
Combined Use ◽  
Age Factor ◽  
The Relationship

The article provides an overview of current data from the scientific literature on the epidemiological features of onychomycosis at present, including changes in the spectrum of pathogens, the nature of the course and clinical manifestations of fungal nail lesions. Current data on the characteristic manifestation of onychomycosis point out the importance of age factor: age-related changes in old population are associated with involutional processes in the skin and its appendages, decreased growth rate of nails, angiopathy, etc. This review demonstrated the relationship between chronic dermatoses and onychomycosis. In chronic dermatoses, including psoriasis, eczema, etc., there are fungal lesions of the nail plates, which cause not only the progression of trophic disorders, increased dryness of the skin and violation of its integrity, but also sensitization of the patient. Onychomycosis complicates the course of chronic dermatoses. In the absence of onychomycosis treatment there is a significant risk of complete destruction of the nail plates with further involvement of the adjacent skin in the pathological process and infection spreading. Three components of effective therapy are identified: accurate diagnosis, correctly selected therapy and compliance. This article also provides the brief description of existing treatment methods of onychomycosis ranging from monotherapy with systemic antifungals to the combined use of systemic and topical antifungals, as well as the use of non-medicinal methods, and in particular methods of ultraphonophoresis, electrophoresis and photodynamics.

scholarly journals Subcortical dementia

2002 ◽  
Vol 180 (2) ◽  
pp. 148-151 ◽  
Author(s):  
Mark A. Turner ◽  
Nicholas F. Moran ◽  
Michael D. Kopelman
Keyword(s):  
Alzheimer’S Disease ◽  
Scientific Literature ◽  
Clinical Manifestations ◽  
Executive Dysfunction ◽  
Memory Deficits ◽  
Subcortical Dementia ◽  
Assessment And Treatment ◽  
Cast Doubt ◽  
Motor Difficulties ◽  
The Relationship

BackgroundDrawing a distinction between cortical and subcortical dementias seems both useful and justified. Recent research has, however, cast doubt on the clinical, neuropsychological, neuroimaging and neuroanatomical basis of the distinction.AimsTo arrive at a reasoned conclusion about the relationship between the two types of dementia and the validity of distinguishing between them.MethodThe historical and recent clinical and scientific literature on subcortical dementia was reviewed.ResultsThe traditional claim that subcortical dementia has distinct clinical manifestations, neuroimaging findings and a neuropathological profile is not altogether borne out by the literature. Some studies show that frontal executive dysfunction and the profile of memory deficits are not significantly different from those seen in Alzheimer's disease. Neuropathological findings also overlap.ConclusionsThe category of subcortical dementia may be clinically useful in highlighting the likelihood that an individual with dementia is more likely to suffer from bradyphrenia and motor difficulties. As neuroscience advances a preoccupation with the distinction may hinder the assessment and treatment of individual cases.

scholarly journals SIGNS OF DISEASES OF THE GASTROINTESTINAL TRACT IN THE ORAL CAVITY OF CHILDREN

2021 ◽  
pp. 112-117
Author(s):  
A.I. Maksymenko
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Clinical Manifestations ◽  
Gastrointestinal Diseases ◽  
Pathological Process ◽  
Combined Lesions ◽  
Dental Diseases ◽  
Group B ◽  
Relationship Of ◽  
The Relationship

The question of combined lesions of the oral cavity and internal organs occupy a prominent place among the problems of dentistry nowadays. They allow to reflect the genesis of many diseases that manifest themselves in the oral cavity. Aim of the study was to analyze information on the relationship of diseases of oral cavity and various diseases of gastrointestinal tract. Anatomical and physiological proximity, common innervation and humoral regulation leads to the involvement of organs of oral cavity in the pathological process. Catarrhal gingivitis, stomatitis are often caused by deficiency of vitamins of group B. Above-mentioned deficiency is caused, according to many scientists, by the diseases of gastrointestinal tract. And such diseases of the oral cavity as chronic recurrent stomatitis, lichen planus, chronic recurrent herpetic stomatitis, chronic periodontitis depends on the pathology of the digestive tract. Conclusions. Thus, anatomical and physiological characteristics of children, who suffers from chronic gastrointestinal diseases, make us study the clinical manifestations of dental diseases in these patients. Prospects for further research. Further study of the dental status of children with diseases of the gastrointestinal tract is very valuable.

INFLUENCE OF MATERNAL CHORIOAMNIONITIS ON NEWBORNS MORBIDITY

2021 ◽  
Vol 100 (1) ◽  
pp. 75-83
Author(s):  
E.A. Shevareva ◽  
◽  
D.O. Ivanov ◽  
O.V. Nevmerzhitskaia ◽  
L.A. Fedorova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Scientific Literature ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Neonatal Morbidity ◽  
Current Data ◽  
Present Review ◽  
Intraamniotic Infection

In recent decades, the problem of chorioamnionitis (CA) (or intra-amniotic infection) takes a leading place in modern obstetrics and perinatology. It is known that CA is one of the main risk factors for preterm birth and increases neonatal morbidity. Intraamniotic infection is a polyetiology condition. It is characterised by the variety of clinical manifestations absence of clearly association between the infection`s clinical signs in mother and infants injury. In present review we defined current data about chorioamnionitis, based on the last evidence of international scientific literature.

CLINICAL AND ETIOLOGICAL FEATURES OF THE PHARYNX ACUTE INFLAMMATION COURSE IN CHILDREN OF DIFFERENT AGE GROUPS

2021 ◽  
Vol 100 (1) ◽  
pp. 130-135
Author(s):  
E.Yu. Radtsig ◽  
◽  
M.M. Evsikova ◽  
Yu.V. Lugovaya ◽  
◽  
...  
Keyword(s):  
Primary School ◽  
Bacterial Flora ◽  
Age Groups ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Culture Method ◽  
Herpes Viruses ◽  
Cervical Lymph Nodes ◽  
Age Related ◽  
The Relationship

The issue of pharynx acute inflammatory pathology is still relevant. Despite the large number of scientific papers and clinical recommendations on this topic, the management of patients with acute tonsillopharyngitis (ATP) is not always rational. Objective of the research: to clarify the relationship between clinical manifestations and etiology of ATP in different age groups in routine outpatient pediatric practice. Materials and methods: 111 children with ATP aged from 1 to 17 years were examined. Patients underwent a routine otorhinolaryngological examination, an express test for group A streptococcus (GAS) detection and a comprehensive microbiological study (in samples from the oropharynx, the bacterial flora was determined by the culture method, respiratory and herpes viruses were detected by the polymerase chain reaction method). Results: in children aged 1 to 7 years, the prevalence of viral-bacterial flora in the ATP etiology was revealed, in patients from 7 years of age and older, the bacterial flora begins to play a major role in the inflammation development. The overall incidence of GAS in the study was 6,3%; it was detected only among children aged 3 to 12 years, herpes viruses were often detected in the same periods of childhood. The study did not reveal any pathognomonic clinical signs only for GAS+ATP, as well as for other pathogens (except a reliable connection between the detection of rhino, adeno and coronavirus in patients with ATP and rhinorrhea). The study revealed age-related features of the ATP course: an increase in the cervical lymph nodes was significantly more often observed at the age of 3 to 12 years, and tonsil stones at primary school age. Conclusion: the study did not reveal the relationship between features of the ATP clinical course and the etiology (including GAS); some age-related features in the preschool and primary school periods were noted.

Gottron’s carcinoid papillomatosis of skin (features of clinical course, diagnosis and treatment, own clinical observation)

2021 ◽  
pp. 15-20
Author(s):  
T.О. Lytynska ◽  
O.V. Demchenko
Keyword(s):  
Clinical Observation ◽  
Clinical Course ◽  
Correct Diagnosis ◽  
Clinical Manifestations ◽  
Pathological Process ◽  
Current Data ◽  
Diagnosis And Treatment ◽  
Rational Approach ◽  
Significant Regression ◽  
Long Course

Objective — to study the features of the clinical course, diagnosis and rational approach to the treatment of Gottron’s carcinoid papillomatosis of skin.Materials and methods. The article presents current data on the clinical course, pathomorphological criteria, diagnosis and treatment of Gottron’s carcinoid papillomatosis of skin. The authors’ own clinical observation is given.Results and discussion. Gottron’s carcinoid papillomatosis of skin is dermatosis that is quite rare in medical practice. The disease is characterized by a long course with a permanent progression of the pathological process. In the vast majority of patients, this pathology develops against the background of other chronic dermatoses such as psoriasis, eczema, lichen planus, pemphigus. In addition, these patients are diagnosed with concomitant multiorgan somatic pathology, which causes not only severe course and recurrence of this dermatosis, but also requires a comprehensive approach to the treatment of these patients, taking into account the identified somatic pathology.Conclusions. Gottron’s carcinoid papillomatosis of the skin is characterized by a long course against the background of permanent progression of the pathological process.Treatment of patients with Gottron’s carcinoid papillomatosis should be comprehensive and individualized, taking into account the severity of dermatosis and concomitant pathology, which is predominantly multiorgan in nature and in some cases causes severe dermatosis and resistance to traditional therapy. This clinical case indicates a significant regression of clinical manifestations of dermatosis in patients with long­term disease, provided the correct diagnosis and adequate therapy.

Operationalization of a frailty index in patients with multiple sclerosis: A cross-sectional investigation

2021 ◽  
pp. 135245852098754
Author(s):  
Daniele Belvisi ◽  
Marco Canevelli ◽  
Viola Baione ◽  
Maria Chiara Buscarinu ◽  
Giulia Pellicciari ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Frailty Index ◽  
Clinical Manifestations ◽  
Analysis Model ◽  
Cross Sectional ◽  
Age Related ◽  
Clinical Complexity ◽  
Multidimensional Health ◽  
The Relationship ◽  
Multiple Health

Background: Frailty is an age-related status of increased vulnerability to stressors caused by the accumulation of multiple health deficits. This construct may allow to capture the clinical complexity of patients with multiple sclerosis (MS). Objective: To investigate the relationship between frailty and the clinical manifestations of MS. Methods: Patients with MS were consecutively enrolled at five tertiary dedicated services. Disability and fatigue were assessed. The phenotypes of MS were also identified. Frailty was measured using a frailty index (FI), computed by cumulatively considering 42 age-related multidimensional health deficits. Results: Overall, 745 MS patients (mean age = 48.2 years, standard deviation = 11.7 years; women 68%) were considered. The median FI value was 0.12 (interquartile range = 0.05–0.19) and the 99th percentile was 0.40. FI scores were associated with MS disease duration, disability, fatigue, as well as with the number of previous disease-modifying treatments and current symptomatic therapies. A logistic regression analysis model showed that FI score was independently associated with the secondary progressive phenotype. Conclusion: Frailty is significantly associated with major characteristics of MS. The findings of the present cross-sectional investigation should be explored in future longitudinal studies.

Cognitive Factors Mediate the Relation Between Age and Flight Path Maintenance in General Aviation

2016 ◽  
Vol 6 (2) ◽  
pp. 81-90 ◽  
Author(s):  
Kathleen Van Benthem ◽  
Chris M. Herdman
Keyword(s):  
Cognitive Functioning ◽  
Flight Path ◽  
General Aviation ◽  
Cognitive Factors ◽  
Pilot Performance ◽  
Pilot Error ◽  
Age Related ◽  
And Performance ◽  
Relationship Of ◽  
The Relationship

Abstract. Identifying pilot attributes associated with risk is important, especially in general aviation where pilot error is implicated in most accidents. This research examined the relationship of pilot age, expertise, and cognitive functioning to deviations from an ideal circuit trajectory. In all, 54 pilots, of varying age, flew a Cessna 172 simulator. Cognitive measures were obtained using the CogScreen-AE ( Kay, 1995 ). Older age and lower levels of expertise and cognitive functioning were associated with significantly greater flight path deviations. The relationship between age and performance was fully mediated by a cluster of cognitive factors: speed and working memory, visual attention, and cognitive flexibility. These findings add to the literature showing that age-related changes in cognition may impact pilot performance.

Modern methods of treating rosacea

2019 ◽  
Vol 1 (7) ◽  
pp. 65-71
Author(s):  
O. A. Egorova ◽  
K. A. Novikov
Keyword(s):  
Clinical Manifestations ◽  
Treatment Method ◽  
Current Data ◽  
Trigger Factors ◽  
Laser Technology ◽  
Individual Approach ◽  
Modern Methods ◽  
Methods Of Treatment ◽  
Choice Of Therapy

Presented current data on the etiology of rosacea, the main aspects of pathogenesis, clinical forms of the disease. Reflects trigger factors leading to rosacea, as well as complicating its course. Modern methods of treatment are described, including the use of new safe preparations of ivermectin and brimonidine, providing a good, lasting effect of clinical manifestations of rosacea. The role of laser technology, actively occupying a leading place in the choice of physiotherapeutic treatment method, is noted. The need for an individual approach in the choice of therapy for each patient with rosacea is emphasized.

ISLAM DAN PANCASILA DALAM PEMIKIRAN MOHAMMAD NATSIR

2019 ◽  
Vol 3 (1) ◽  
pp. 82
Author(s):  
Mhd Alfahjri Sukri
Keyword(s):  
Political Parties ◽  
Qualitative Method ◽  
Political Socialization ◽  
Scientific Literature ◽  
Research Data ◽  
The Political ◽  
Direct Influence ◽  
Childhood Environment ◽  
Political Conditions ◽  
The Relationship

This research was conducted to see how Mohammad Natsir thought about the relationship between Islam and Pancasila. This study also explains the causes of Natsir's change of mind which initially supported Pancasila as part of Islam and later turned into an opponent of Pancasila in Konstituante on 11 November to 6 December 1957. The methodology used was a qualitative method by describing the results of the analysis carried out. The research data is obtained through a review of documents and scientific literature. The results of the study show that Mohammad Natsir's change of mind regarding the relationship between Islam and Pancasila was influenced by Mohammad Natsir's political socialization which began from Natsir's view of Islam influenced by the childhood environment (conditional and socio-cultural) in Minangkabau; direct influence from national figures such as Ahmad Hassan, H. Agus Salim, Sheikh Ahmad Syurkati and H. O Tjokroaminoto; the indirect influence of international figures throughout reading book such as Hassan Al-Banna, Amir Syakib Arselan, Rashid Ridha and Muhammad Abduh; the influence of Natsir's organization and political parties, namely Jong Islamieten Bond (JIB), Islamic Unity (Persis), and Masyumi political parties; and the influence of the political conditions at that time which made Natsir's views change, which initially accepted Pancasila and then became an opponent of the Pancasila. This research shown there are two patterns of Natsir's relationship with Pancasila, namely (1) Natsir accepted Pancasila and, (2) Natsir opposed Pancasila.

О НЕКОТОРЫХ ИСТОРИЧЕСКИХ АСПЕКТАХ СТАНОВЛЕНИЯ ВОСПИТАТЕЛЬНОЙ РАБОТЫ С ОСУЖДЕННЫМИ В МЕСТАХ ЛИШЕНИЯ СВОБОДЫ

2020 ◽  
Author(s):  
Vasiliy Dvortsov ◽  
Alexander Efimenko
Keyword(s):  
General Education ◽  
Scientific Literature ◽  
Criminal Code ◽  
The Self ◽  
Self Assessment ◽  
Educational Work ◽  
Legal Norms ◽  
Education Profession ◽  
Comprehensive Programs ◽  
The Relationship

В статье предпринята попытка теоретического анализа и изучения научной литературы по организации и становлению воспитательной работы с осужденными в местах лишения свободы, продемонстрирована взаимосвязь между политико-воспитательной работой, ресоциализацией и исправлением осужденных в пенитенциарных учреждениях. Проведенное исследование позволяет предполагать, что воспитательная работа является основополагающим средством исправления различных категорий осужденных (регламентировано ст. 9 УИК РФ). На этой основе критерием исправления будет становиться устойчивое правопослушное поведение человека. В связи с этим возникает необходимость использования психолого-педагогической программы по перестройке и самооценке осужденных, позволяющей формировать их готовность к самореализации, когда осознание совершенных преступлений становится внутренне неприемлемым. Авторами отмечается, что, самоисправление человека зависит от ряда направлений воспитательной работы: нравственного, правового, физического воспитания, получения основного общего образования, получения профессии. Очевидно, что для закрепления положительного результата процесс ресоциализации в пенитенциарных учреждениях должен проводиться сотрудниками всех отделов и служб на основе комплексных программ, разработанных с учетом специфики и возраста осужденных.The article attempts a theoretical analysis and study of scientific literature on the organization and formation of educational work with convicts in prisons, demonstrates the relationship between «political and educational work», re-socialization and correction of convicts in prisons. The study suggests that educational work is a fundamental means of correcting various categories of convicts (regulated by article 9 of the criminal code). Based on this criterion fixes will become sustainable human behavior, demonstrating a conscious rejection of the violation of legal norms with the aim of securing sustainable patterns of law-abiding behavior. There is a need to use the psychological and pedagogical Program for restructuring and self-assessment of convicts, which allows to form on this basis their readiness for self-realization, when the awareness of the crimes committed becomes internally unacceptable. In this regard, the self-correction of a person depends on a number of areas, namely, moral, legal, physical education, basic General education, profession, forming the basis of educational work. It is obvious that in order to consolidate a positive result in penitentiary institutions, the activities of all departments and services should be carried out a process of re-socialization on the basis of comprehensive Programs developed taking into account the specifics and different ages of convicts.

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