PHENOLIC PROFILE AND ANTIOXIDANT ACTIVITY OF A SEMPERVIVUM RUTHENICUM KOCH ETHANOLIC EXTRACT

The genus of the Zygophyllaceae family includes evergreen shrub species. Background highlights the antioxidant and anti-tumor activity of Larrea divaricate and nordihydroguayaretic acid (NDGA) due to their potential as a dietary supplement and food preservative, but little is known about Larrea cuneifolia. The aim of this work was to determine the antioxidant characteristics of ethanolic extracts of L. cuneifolia leaves collected in the central valley of Catamarca (Argentina). Total polyphenols content (TP) was determined by Folin-Ciocâlteu and the phenolic profile by HPLC-PDA-QTOF. The antioxidant activity was measured by in vitro (FRAP, TEAC and DPPH) and cellular (HepG2 and Caco2 cells) assays. The phenolic compounds identified were mainly derivatives of NDGA and flavonols derivatives of quercetin, kaempferol, isorhamnetin and gossypetin. TP content and antioxidant activity exceeded the values reported for L. divaricata. With regard to cytotoxicity, an increase in this parameter could be observed with the increase in the concentration of polyphenols in both cell types. Furthermore, in cells exposed to H2O2, a significant decrease in reactive oxygen species (ROS) concentration was observed for HepG2 cells. This effect can be used to study compounds with bioactivity on tumor cells. L. cuneifolia is a species rich in phenolic compounds, with antioxidant properties, and is a potential source of bioactive compounds for the production of functional foods.

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Phenolic profile and antioxidant activity of buckwheat (Fagopyrum esculentum) herb and root extracts

Planta Medica ◽

10.1055/s-0032-1321348 ◽

2012 ◽

Vol 78 (11) ◽

Cited By ~ 1

Author(s):

D Orcic ◽

E Svirčev ◽

N Mimica-Dukic ◽

I Beara ◽

K Balog ◽

...

Keyword(s):

Antioxidant Activity ◽

Fagopyrum Esculentum ◽

Phenolic Profile ◽

Root Extracts

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The influence of chitin derivatives on the antioxidant activity and phenolic profile in Echinacea purpurea

Annales UMCS Pharmacia ◽

10.2478/v10080-008-0138-2 ◽

2008 ◽

Vol 21 (2) ◽

pp. 309-311

Author(s):

Maria Burdova ◽

Jozef Hudec ◽

Ivan Turianica ◽

Radka Kochanova ◽

Larysa Rostoka

Keyword(s):

Antioxidant Activity ◽

Echinacea Purpurea ◽

Phenolic Profile ◽

Chitin Derivatives

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UJI AKTIVITAS ANTIOKSIDAN FRAKSI N-HEKSAN DAUN AFRIKA (Vernonia amygdalina Del.) DENGAN METODE DPPH

Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan ◽

10.36387/jiis.v5i2.466 ◽

2020 ◽

Vol 5 (2) ◽

pp. 250-257

Author(s):

Nurul Fatimah ◽

◽

Reksi Sundu

Keyword(s):

Oxidative Stress ◽

Antioxidant Activity ◽

Free Radicals ◽

Ethanolic Extract ◽

Ethanol Extract ◽

Hexane Fraction ◽

Phytochemical Screening ◽

Vernonia Amygdalina ◽

Tropical Africa ◽

Ic50 Value

Free radicals and reactive species are widely believed to contribute to the development of several diseases by causing oxidative stress and eventually oxidative. Vernonia amygdalina (Astereacea) is a small shrub or tree between 1 and 5m high growing throughout tropical Africa. Plants are generally known as bitter leaves is well cultivated and is a general market for merchandise in several countries. The purpose of this study was to determine the antioxidant activity of hexane fraction from ethanol extract od Frican leaves (Vernonia amygdalina Del.). The method used in this study was the DPPH (1,1-Diphenil-2-Picrylhydrazyl) method. The result of phytochemical screening showed that ethanolic extract of African leaves contained a composition of secondary metabolites of alkaloids, flavonoids, tannins, steroids/triterpenoids and saponins. The antioxidant activity of the extract of n-hexane fraction was classified as very weak with an IC50 value of 317.98 ppm.

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Antioxidant activity and nitrite scavenging ability of each fractions from Phyllostachys bambusoides ethanolic extract

Oriental Pharmacy and Experimental Medicine ◽

10.3742/opem.2005.5.3.209 ◽

2005 ◽

Vol 5 (3) ◽

pp. 209-215

Keyword(s):

Antioxidant Activity ◽

Ethanolic Extract ◽

Phyllostachys Bambusoides

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Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2019-0136 ◽

2020 ◽

Vol 17 (3) ◽

Author(s):

Emmanuel Tiyo Ayikobua ◽

Josephine Kasolo ◽

Keneth Iceland Kasozi ◽

Ejike Daniel Eze ◽

Abass Safiriyu ◽

...

Keyword(s):

Antioxidant Activity ◽

Drosophila Melanogaster ◽

Side Effects ◽

Motor Activity ◽

Ethanolic Extract ◽

Synergistic Action ◽

Content Type ◽

Treatment Groups ◽

Ethanolic Extract Of Propolis ◽

Different Doses

AbstractBackgroundThe Phosphatase and tensin-induced putative kinase 1 (PINK1B9) mutant for Drosophila melanogaster is a key tool that has been used in assessing the pathology of Parkinsonism and its possible remedy. This research was targeted toward determining the effects of ethanolic extract of propolis, with levodopa therapy in the management of Parkinsonism.MethodThe PINK1B9 flies were divided into groups and fed with the different treatment doses of ethanoic extract of propolis. The treatment groups were subjected to 21 days of administration of propolis and the levodopa at different doses after which percentage climbing index, antioxidant activity and lifespan studies were done.ResultsPropolis alone improved motor activity, antioxidant and lifespan in Drosophila melanogaster than in PINK1 flies. Propolis in combination with levodopa significantly (P<0.05) improved physiological parameters at higher than lower concentrations in Parkinsonism Drosophila melanogaster demonstrating its importance in managing side effects associated with levodopa.ConclusionPropolis is a novel candidate as an alternative and integrative medicinal option to use in the management of Parkinsonism in both animals and humans at higher concentrations.

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Preliminary Characterisation of Wastes Generated from the Rapeseed and Sunflower Protein Isolation Process and Their Valorisation in Delaying Oil Oxidation

Food and Bioprocess Technology ◽

10.1007/s11947-021-02695-y ◽

2021 ◽

Author(s):

Miluska Cisneros-Yupanqui ◽

Vesela I. Chalova ◽

Hristo R. Kalaydzhiev ◽

Dasha Mihaylova ◽

Albert I. Krastanov ◽

...

Keyword(s):

Antioxidant Activity ◽

Protocatechuic Acid ◽

Activity Index ◽

Natural Antioxidants ◽

Total Phenolic ◽

Protein Isolation ◽

Phenolic Profile ◽

Oilseed Crops ◽

Sunflower Protein ◽

Main Representative

AbstractSince rapeseed and sunflower meals are two of the most representative oilseed crops in the world, this study was focused on ethanol-wash solutes (EWS) obtained as wastes from the protein isolation process of rapeseed and sunflower meals. These meals have been previously valorised; however, the use of the EWS is unexplored. The present study is aimed at the characterisation of their phenolic profile, and antioxidant capacity for preventing lipid oxidation in rapeseed, sunflower, and soybean oil, which has been used as a reference oil. The sunflower EWS exhibited more total phenolic compounds (TPC) and antioxidant activity (119.39 ± 1.13 mg GA/g and 193.97 ± 9.77 mg TE/g, respectively) than the rapeseed one (103.44 ± 5.94 mg GA/g and 89.51 ± 3.17 mg TE/g). The phenolic identification showed hydroxybenzoic and protocatechuic acid in the rapeseed EWS, and pyrogallol and caffeic acid in the sunflower EWS, as the main representative phenols. Both EWS at 15% increased significantly (p < 0.05) the oxidative stability of the oils in the Rancimat equipment with values of antioxidant activity index (AAI) from 1.01 to 1.20, depending on the type of oil employed. In conclusion, the rapeseed and sunflower EWS showed great potential, and they could be used as a source of natural antioxidants within the food industry, replacing the synthetic ones, and promoting the circular economy since they are agro-food wastes.

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