scholarly journals Construction of a Physical Factor Resource for Exposome Informatics Research

Author(s):  
Christopher Hawthorne ◽  
Niamh Quigley ◽  
Callum McClements ◽  
Guillermo H. Lopez-Campos

Exposome research is focused on all the exposures individuals experience during their lifetime and how it shapes their health and development of disease. The chemical and biological aspects of the exposome are readily available in data formats. In comparison there is a lack of data frameworks available for physical factors (e.g. noise, lighting, electromagnetic fields) and their biological relationships which would allow a greater understanding of the contribution of the physical environment on disease development and burden. We present the construction of a prototype that captures knowledge on physical factors and their interactions with genes and diseases derived from the biomedical literature to reflect the physical exposome.

FLORESTA ◽  
2019 ◽  
Vol 49 (4) ◽  
pp. 821
Author(s):  
Cristiane Roppa ◽  
Ricardo Valcarcel ◽  
Márcio Rocha Francelino ◽  
Vivivan Castilho Da Costa ◽  
Newton De Magalhães Neto

Intense and constant anthropic interventions transform extensive forest landscapes into mosaics of disturbed or degraded ecosystems. These ecosystems can restore themselves spontaneously, depending on the attributes offered by the physical environment and their capacity for resilience. This study’s objectives were the identification of plant formations in a conservation unit and the variables of the physical environment which favor the spontaneous restoration processes of the landscape. These variables were divided into classes using ArcGIS 10 and analyzed through the Principal Component Analysis. The concave curvature of the terrain was the physical factor which best contributed to the formation of a secondary forest in medium and advanced stages of succession, indicating that curvature is the determining factor for the spontaneous restoration of the landscape.


2018 ◽  
Vol 6 (2) ◽  
pp. 305-313 ◽  
Author(s):  
Tatiana Danilchuk ◽  
Tatiana Danilchuk ◽  
Vera Ganina ◽  
Vera Ganina

The paper deals with urgent issues of development of resource-saving methods of biotechnological processes intensification. The main purpose of the work is to show the efficiency of using extremely low doses of physical factors impact in food biotechnology. Acoustic and electric treatment was in various modes. Impact capacity did not exceed 10-4 W/kg. The duration of exposure ranged from 5 to 15 min. Barley grains enzymes and lactic acid microorganisms were subjected to treatment. Impact of vibration as a physical factor, its frequency is considered as a priority in controlling growth and biochemical processes in biological objects. Impact frequency in the range of 50–10000 Hz influences the activity of hydrolytic enzymes in bimodal way. It is presented in the article. The coincidence of the frequency ranges of the maximum activity of enzymes in the model reactions with the ones in the grain of barley under the treatment of alternating current and sound is noted. Improvement of all indexes of germinating barley and improvement of the quality of the finished malt were observed in these ranges. Low-intensity acoustic treatment at a frequency of 2000 Hz contributed to an increase in β-galactosidase activity of the CT-95 Str. thermophilus strain. Selected ST-95 Str. thermophilus strain was used in the starter composition for the experimental sample production of fermented melted milk. The fermentation process intensification was observed. The lactose content of this product is 30% less in comparison with the feedstock. The use of traditional starter without a selected strain can reduce the lactose content by an average of 7.5%. The results of biotechnological processes modification by means of the treatment of enzymes and extremely low doses of physical factors impact used in meat technologies are observed. Thus, the prospects of using low-intensity physical effects of vibration in the development of innovative food technologies are substantiated. It is also promising to use these technologies in making absolutely new food products with different qualities.


1953 ◽  
Vol 85 (8) ◽  
pp. 297-310 ◽  
Author(s):  
C. R. Sullivan ◽  
W. G. Wellington

The forest tent caterpillar, Malacosoma disstria Hbn., and the eastern and western tent caterpillars, M. americanum (Fab.) and M. pluviale (Dyar), are common pests of several species of deciduous trees in Canada. All are colonial during the larval stage, but M. disstria differs from the others in one respect: it does not construct a communal tent. This difference in habit merits special consideration in any comparative study of larval behaviour, particularly in one concerned with the effects of physical factors upon the insects, since a tent modifies the effects of the physical environment considerably. Recently, a series of such studies was carried out, and one part of the work consisted of laboratory and field observations on the light reactions of larvae. The results obtained have raised a number of new questions which unfortunately cannot be answered now, hecause two of the species have been difficult to obtain in quantity since 1950. Nevertheless, the findings are presented here without additional delay, since they are of general interest, and other workers may wish to use them.


2019 ◽  
Vol 8 (4) ◽  
pp. 5327-5330

MANETs is a network which has nodes. Communication is done without use of infrastructure. Quality based routing is developed which considers end to end qualitatiove data communication. A number of protocols were designed and suggested by researchers to achieve effective communication in MANETs. Considering number of quality factors as energy, trust, bandwidth etc a number of protocols are existing. But still there are number of factors those can consider to enhance the performance of the protocols used for the communication purpose. The existing schemes were effective enough but still as factors those were considering only the resources held by a node not the physical factors were present as node is to survive and communication in network. So further enhancements were possible by considering the physical parameters. Inspired from that in this paper a proposed scheme considering physical factor name as Distance is considered as the improvement to the traditional scheme. The distance factor is behaving as finding the physical presence of the node in the network also the distance factor will help to find the appropriate node for the next hop to communicate. A simulation is conducted in MATLAB software and performance factors as throughput and energy are analyzed, also an comparison with existing system is done and the results shows that the proposed scheme is effective enough to achieve QOS based routing with reduced energy consumption and high throughput.


2004 ◽  
Vol 26 (2) ◽  
pp. 178 ◽  
Author(s):  
Catherine Allan ◽  
R. D. B. Whalley

Microlaena stipoides is widespread in the higher rainfall areas of Australia. It is consistently reported in the literature as providing high quality forage, yet anecdotal evidence suggests a wide range of opinions about the value of M. stipoides among graziers who manage areas with abundant M. stipoides. This paper addresses three questions relating to this divergence of opinion. Are landholders responding to inherent variability within M. stipoides? Is M. stipoides responding to different site and management conditions, prompting landholders to value it preferentially where site or management suit? Or are the landholders' judgments of M. stipoides influenced less by the actual performance of the grass on their properties than by social factors? Data collected from ten properties in the Victorian Upper Murray included a morphological assessment of M. stipoides samples, quantitative site and pasture information and qualitative data from interviews with property managers. Ecotypic variation and responses to site and management variables were found, but there were no apparent relationships between these parameters and the value judgments made by the landholders. The only physical factor which appeared to have any influence on landholder opinion was the annual rainfall for their property, although this was not through direct impact on other site attributes. It seems that social rather than physical factors may need to be explored in order to understand the factors influencing landholder opinion of M. stipoides.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Dong-Pyo Han ◽  
Gyeong Won Lee ◽  
Sangjin Min ◽  
Dong-Soo Shin ◽  
Jong-In Shim ◽  
...  

Abstract This study aims to elucidate the carrier dynamics behind thermal droop in GaInN-based blue light-emitting diodes (LEDs) by separating multiple physical factors. To this end, first, we study the differential carrier lifetimes (DCLs) by measuring the impedance of a sample LED under given driving-current conditions over a very wide operating temperature range of 300 K–500 K. The measured DCLs are decoupled into radiative carrier lifetime (τR) and nonradiative carrier lifetime (τNR), via utilization of the experimental DCL data, and then very carefully investigated as a function of driving current over a wide range of operating temperatures. Next, to understand the measurement results of temperature-dependent τR and τNR characteristics, thermodynamic analysis is conducted, which enables to look deeply into the temperature-dependent behavior of the carriers. On the basis of the results, we reveal that thermal droop is originated by the complex dynamics of multiple closely interrelated physical factors instead of a single physical factor. In particular, we discuss the inherent cause of accelerated thermal droop with elevated temperature.


2019 ◽  
Vol 8 (4) ◽  
pp. 5-12
Author(s):  
B. S. Kasparov ◽  
T. Yu. Semiglazova ◽  
D. V. Kovlen ◽  
G. N. Ponomarenko ◽  
V. A. Klyuge ◽  
...  

During last 10 years the number of studies which devoted to using of medical physical factors in rehabilitation of patients with breast cancer has increased. Using any physical factor in rehabilitation should be proved by results of evidence-based studies.The article presents data of scientometric analysis of 748 studies from 1980 till 2018 which were devoted to using of medical physical factors in rehabilitation of 261643 patients with breast cancer. The most studied physical factors with authentically proven effect are physical exercises, water based physical exercises, compression therapy. Process of synthesis and analysis of study results should be done regularly.


2021 ◽  
Vol 6 (166) ◽  
pp. 169-174
Author(s):  
O. Panova

Analysis of national and international databases on the safety of physical factors. Non-regulatory working conditions of computer users are largely due to the lack of national sanitary norms and rules for the safe operation of computer equipment. Current international standards relate to the radiative properties of technical means and do not consider the conditions in the workplace. It is shown that general standards on maximum permissible levels of physical factors are unacceptable for their application in the field of user safety due to high maximum permissible levels of electromagnetic fields, infrasound, electrostatic fields, etc. In addition, there are significant differences in the various current regulations regarding limit levels and methods for determining the integrated electromagnetic load. When developing sanitary norms for the safety of users of computer equipment, the dependence of air quality on the aeroionic composition on the presence of surface electrophysical charges on polymer surfaces and models of technical means and means of air cooling should be taken into account. It is advisable to regulate the use of artificial air ionization devices. Given the relatively low levels of electromagnetic fields in the workplace of users, it is necessary to regulate the ways of controlling the levels of electromagnetic fields with acceptable errors. Given the impact of unstable operation of technical ways on the psychomatic state of users in the process of developing the relevant standard, it is necessary to take into account the stable operation of equipment by increasing the levels of electromagnetic compatibility of equipment.


2018 ◽  
Vol 3 (1) ◽  
pp. 176
Author(s):  
Risna Cintiani ◽  
Hady Siti Hadijah

There are many factors that can cause teachers to get job satisfaction where they work. One of them is environmental factor especially non environment physical factor that is environment of work place of employee in the form of harmonious work atmosphere between subordinate with superior (vertical relationship) and between fellow employees (horizontal relationship). This study aims to determine whether or not the influence of non-physical environmental factors on job satisfaction of teachers in a vocational school in Cimahi. This research use explanatory survey method. Data obtained through questionnaires distributed to 51 selected teachers as sample. The statistical tool used is simple linear regression. Result of research indicate that there is influence of non working physical environment to job satisfaction of teacher at SMK PGRI 3 Cimahi.ABSTRAKTerdapat banyak faktor yang dapat menyebabkan para guru mendapatkan kepuasan kerja di tempat mereka bekerja. Salah satunya adalah faktor lingkungan terutama faktor lingkungan non fisik yaitu keadaan lingkungan tempat kerja pegawai berupa suasana kerja yang harmonis antar bawahan dengan atasan (hubungan vertikal) serta antar sesama pegawai (hubungan horisontal). Penelitian  ini bertujuan untuk mengetahui ada tidaknya pengaruh faktor lingkungan non fisik terhadap kepuasan kerja guru pada sebuah SMK di Cimahi. Penelitian ini  menggunakan metode explanatory survey. Data yang diperoleh melalui angket  yang disebar kepada 51 guru terpilih sebaGai sampel. Alat statistik yang digunakan adalah regresi linier sederhana. Hasil penelitian menunjukkan bahwa terdapat pengaruh lingkungan kerja non fisik terhadap kepuasan kerja guru di SMK PGRI 3 Cimahi


Author(s):  
Abraham Octavio RODRÍGUEZ-DE LA FUENTE ◽  
Ricardo GOMEZ-FLORES ◽  
José Antonio HEREDIA-ROJAS ◽  
Edna Marbella GARCÍA-MUÑOZ ◽  
Javier VARGAS-VILLARREAL ◽  
...  

Background: There is an increasing interest in using physical factors such as magnetic fields as antimicrobial strategy, with variable results. The current study was aimed to evaluate the influence of extremely low-frequency electromagnetic fields (ELF-EMFs) on the axenically-cultured parasite protozoans Trichomonas vaginalis and Giardia lamblia growth. Methods: Bioassays were developed using T. vaginalis, GT-13 and G. lamblia IMSS-0989 strains cultured at 37 ºC in TYI-S-33 medium. The following treatment regimens and controls were considered: (a) cells exposed to ELF-EMFs, (b) untreated cells, (c) cells treated with Metronidazole, used as positive controls, and (d) cells co-exposed to ELF-EMFs and Metronidazole. When cultures reached the end of logarithmic phase, they were exposed to ELF-EMFs for 72 h, in a standardized magnetic field exposure facility. For determining cytotoxic effects, trophozoite density was blindly evaluated in a Neubauer chamber. Results: A significant decrease in trophozoite growth was observed for T. vaginalis, in magnetic field-treated cultures. On the other hand, cultures co-exposed to ELF-EMFs and Metronidazole showed no significant differences when compared with cultures treated with Metronidazole alone. On the contrary, an increased trophozoite density was observed in G. lamblia cultures after exposure to magnetic fields. An absence of a synergistic or antagonistic effect was observed. Conclusion: ELF-EMFs induced T. vaginalis and G. lamblia growth alterations, indicating a potential effect in cell cycle progression.


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