Associations Between Sleep Quality, Household Income and Medication Adherence in Adolescents With Asthma

Adolescents with asthma are at-risk for poor sleep quality. Little research has examined the relationship between sleep quality and inhaled corticosteroids (ICS) adherence. Individuals from lower-income backgrounds experience disparities that may alsocontribute to sleep quality. This study sought to 1) examine associations between household income and sleep quality and 2) analyze the relationship between sleep quality and ICS adherence among adolescents with asthma.Forty-one adolescents with persistent asthma (Mage = 14.83, SD = 1.28) completed the Adolescent Sleep Wake Scale (ASWS) to measure sleep quality across five subscales. Caregivers provided their estimated household income per year and completed a free response question measuring ICS adherence. Spearman’s rank-order correlations were used to examine associations between sleep quality,household income and ICS adherence. Sleep quality and household income were not significantly related (r = .262, p = .098). Sleep quality was not associated with ICS adherence (r = -.028, p = .867). Sleep quality was not significantly related to household income or ICS adherence in adolescents with asthma. Limitations include limited power given a small sample size and less reliable measures of household income and adherence therefore, future directions should focus on using more precise measures. Additional research with larger sample sizes may help better understand potential relationships between sleep quality, ICS adherence, and household income within youth with asthma.

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0046 Diffusion Tensor Imaging Evidence of Hypothalamic Injury in Traumatic Brain Injury Warfighters with Sleep Dysfunction

SLEEP ◽

10.1093/sleep/zsaa056.045 ◽

2020 ◽

Vol 43 (Supplement_1) ◽

pp. A19-A19

Author(s):

K Werner ◽

B Gerstenslager ◽

P Yeh ◽

R Srikanchana ◽

K Kenney ◽

...

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Sleep Quality ◽

Linear Models ◽

Diffusion Tensor ◽

Small Sample Size ◽

Small Sample ◽

Poor Sleep ◽

Sleep Dysfunction ◽

California Institute Of Technology

Abstract Introduction While sleep disorders occur in 40–70% of chronic traumatic brain injury (TBI) patients, the pathophysiology remains unknown. Increasingly, DTI has been used to evaluate gray matter structures, but no prior studies have evaluated hypothalamic regions in TBI. We hypothesized that TBI patients with poor sleep quality by questionnaire and/or polysomnography (PSG) may have structural injury to hypothalamic sleep circuitry and that this may be detectable by diffusion magnetic resonance imaging (dMRI). We examined diffusion tensor parameters in warfighters using dMRI within the hypothalamus of poor sleepers and compared them to good sleepers. Methods A retrospective review of 92 warfighters with blast TBI and loss of consciousness included demographics, structural MRI, dMRI, PSG and Pittsburgh Sleep Quality Index (PSQI) questionnaire. Acquisition of diffusion-weighted and structural data was performed with three Tesla MRI. Using the California Institute of Technology probabilistic high-resolution in vivo atlas as a prior, the hypothalamic nuclei were segmented by applying diffeomorphic registration of T1- and T2-weighted structural images and mapped to dMRI space. Results TBI patients within the lowest quartile of hypothalamic fractional anisotropy (FA) measures demonstrated decreased total sleep time (320 +/- 52 minutes vs. 382 +/- 19, p=0.006) on PSG and had more sleep complaints on PSQI (p=0.029) compared to those with the highest quartile of FA measures. There was no difference in BMI, age or AHI among the quartiles. Radial, mean and axial diffusivity quartiles did not carry significant differences in TST or PSQI. Linear models did not show significant correlation between any imaging parameter and sleep quality measures. Conclusion Our results reveal microstructural differences in the hypothalami of military TBI patients that may be related to clinical sleep dysfunction. Biomarkers of sleep circuitry damage may further our understanding of sleep dysfunction after TBI. Lack of correlations in linear models may be a reflection of the small sample size or a complex interaction, and removal of outliers did not change our results. Larger longitudinal studies may help clarify the association between hypothalamic and brainstem circuitry structure after TBI and sleep dysfunction. Support This work was supported by a grant 130132 from USAMRMC.

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Relationship between Leader Behaviours and Subordinates’ Work Performance

International Journal of Research in Business and Social Science (2147-4478) ◽

10.20525/ijrbs.v8i1.180 ◽

2019 ◽

Vol 8 (1) ◽

pp. 50-63

Author(s):

Neria Magombo-Bwanali

Keyword(s):

Work Performance ◽

Rank Order ◽

Small Sample Size ◽

Small Sample ◽

Tax Administration ◽

Team Leaders ◽

Frequency Distributions ◽

Leadership Behaviour ◽

Public Organisations ◽

The Relationship

The paper assesses the relationship between leader behaviours and subordinates’ work performance in the context of tax administration. Data were collected in Malawi using two validated questionnaires administered online for subordinates and team leaders at a field office of a tax administration. Frequency distributions were used to identify dominant primary leader behaviours and the Spearman’s rank-order correlation analysis was used to assess the relationship between leader behaviours and subordinates’ work performance. Participative path-goal leadership behaviour is the most common primary leadership behaviour that team leaders in tax administration employ. Secondly, supportive and achievement oriented leader behaviours have a significant relationship with subordinates’ work performance in tax administration. The study concluded that achievement oriented path-goal leadership behaviour could be effective for public organisations involved in law enforcement. It is recommended that leaders should conduct a self-assessment of their leadership; adopt the relations-oriented leadership behaviours and incorporate coaching during performance evaluation exercise; and that organisations should equip leaders with leadership and management skills through training.The study is limited by the small sample-size, therefore, future studies could repeat the assessment with a larger sample and determine the mathematical equations for predicting the effect of each leadership behaviour on subordinates’ work performance.

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THE RELATIONSHIP BETWEEN SMART PHONE USAGE AND SLEEP DISTURBANCES AND PSYCHOLOGICAL DISSTRESS AMONG STUDENTS

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2017.4.19 ◽

2017 ◽

pp. 125-130

Author(s):

Minh Tam Nguyen ◽

Phuc Thanh Nhan Nguyen ◽

Thi Thuy Hang Nguyen

Keyword(s):

High School ◽

High School Students ◽

University Students ◽

Sleep Quality ◽

Sleep Disturbances ◽

Public Health Problem ◽

Smartphone Addiction ◽

Poor Sleep ◽

School Students ◽

The Relationship

The increasing use of smartphone among young people is creating negative effects and is an important public health problem in many countries. Smartphone abuse and addiction may cause physical and psychological disorders among users. However, the awarenes on this issue has been inadequate due to lacking of evidence. Objectives: To describe the current situation of smartphone using among students at highschools and universities in Hue city and to examine the relationship between smartphone using and sleep disturbances and psychological disstress among participants. Methods: A cross-sectional study with a randomly selected sample of 1,150 students at highschools and universities in Hue city. SAS-SV scale was used to evaluate phone addiction status, K10 scale was used for psychological distress assessment and PSQI scale was used to examine the sleep quality. Results: The proportion of students at highschools and universities having smartphones was 78.0%. The rate of smartphone addiction among high school students was 49.1% and that among university students was 43.7%. There was 57.3% of high school students had poor sleep quality, and that of university students was 51.6%. There was a statistically significant association between smartphone addiction and sleep disturbances and psychological disstress among participants (p <0.05). Conclusion: The prevalence of smartphone addiction among students at highschools and universities is alarming and is related to sleep disturbances and psychological disstress among participants. There is a strong call to develop intervention to help students to aware and manage the use of smartphone effectively.

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POS1465-HPR THE RELATIONSHIP BETWEEN SEDENTARY BEHAVIOR AND SLEEP IN RHEUMATOID ARTHRITIS: A CROSS-SECTIONAL STUDY

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2021-eular.641 ◽

2021 ◽

Vol 80 (Suppl 1) ◽

pp. 1017.2-1018

Author(s):

N. Kelly ◽

E. Hawkins ◽

H. O’leary ◽

K. Quinn ◽

G. Murphy ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Physical Activity ◽

Sleep Quality ◽

Sedentary Behavior ◽

Disease Duration ◽

Cross Sectional Study ◽

P Value ◽

Poor Sleep ◽

Cross Sectional ◽

The Relationship

Background:Rheumatoid arthritis (RA) is a chronic, autoimmune inflammatory condition that affects 0.5% of the adult population worldwide (1). Sedentary behavior (SB) is any waking behavior characterized by an energy expenditure of ≤1.5 METs (metabolic equivalent) and a sitting or reclining posture, e.g. computer use (2) and has a negative impact on health in the RA population (3). Sleep is an important health behavior, but sleep quality is an issue for people living with RA (4, 5). Poor sleep quality is associated with low levels of physical activity in RA (4) however the association between SB and sleep in people who have RA has not been examined previously.Objectives:The aim of this study was to investigate the relationship between SB and sleep in people who have RA.Methods:A cross-sectional study was conducted. Patients were recruited from rheumatology clinics in a large acute public hospital serving a mix of urban and rural populations. Inclusion criteria were diagnosis of RA by a rheumatologist according to the American College of Rheumatology criteria age ≥ 18 and ≤ 80 years; ability to mobilize independently or aided by a stick; and to understand written and spoken English. Demographic data on age, gender, disease duration and medication were recorded. Pain and fatigue were measured by the Visual Analogue Scale (VAS), anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS), and sleep quality was assessed using the Pittsburgh Sleep Quality Index. SB was measured using the ActivPAL4™ activity monitor, over a 7-day wear period. Descriptive statistics were calculated to describe participant characteristics. Relationships between clinical characteristics and SB were examined using Pearson’s correlation coefficients and regression analyses.Results:N=76 participants enrolled in the study with valid data provided by N=72 participants. Mean age of participants was 61.5years (SD10.6) and the majority 63% (n = 47) were female. Participant mean disease duration was 17.8years (SD10.9). Mean SB time was 533.7 (SD100.1) minutes (8.9 hours per day/59.9% of waking hours). Mean sleep quality score was 7.2 (SD5.0) (Table 1). Correlation analysis and regression analysis found no significant correlation between sleep quality and SB variables. Regression analysis demonstrated positive statistical associations for SB time and body mass index (p-value=0.03846, R2 = 0.05143), SB time and pain VAS (p-value=0.009261, R2 = 0.07987), SB time and HADS (p-value = 0.009721, R2 = 0.08097) and SB time and HADSD (p-value = 0.01932, R2 = 0.0643).Conclusion:We found high levels of sedentary behavior and poor sleep quality in people who have RA, however no statistically significant relationship was found in this study. Future research should further explore the complex associations between sedentary behavior and sleep quality in people who have RA.References:[1]Carmona L, et al. Rheumatoid arthritis. Best Pract Res Clin Rheumatol 2010;24:733–745.[2]Anon. Letter to the editor: standardized use of the terms “sedentary” and “sedentary behaviours”. Appl Physiol Nutr Metab = Physiol Appl Nutr Metab 2012;37:540–542.[3]Fenton, S.A.M. et al. Sedentary behaviour is associated with increased long-term cardiovascular risk in patients with rheumatoid arthritis independently of moderate-to-vigorous physical activity. BMC Musculoskelet Disord 18, 131 (2017).[4]McKenna S, et al. Sleep and physical activity: a cross-sectional objective profile of people with rheumatoid arthritis. Rheumatol Int. 2018 May;38(5):845-853.[5]Grabovac, I., et al. 2018. Sleep quality in patients with rheumatoid arthritis and associations with pain, disability, disease duration, and activity. Journal of clinical medicine, 7(10)336.Table 1.Sleep quality in people who have RASleep variableBed Time N(%) before 10pm13(18%) 10pm-12pm43 (60%) after 12pm16 (22%)Hours Sleep mean(SD)6.56 (1.54)Fall Asleep minutes mean(SD)33.3(27.7)Night Waking N(%)45(63%)Self-Rate Sleep mean(SD)2.74 (0.90)Hours Sleep mean(SD)6.56 (1.54)Disclosure of Interests:None declared

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Improving new product development performance by risk management

Journal of Business and Industrial Marketing ◽

10.1108/jbim-04-2013-0090 ◽

2016 ◽

Vol 31 (3) ◽

pp. 418-425 ◽

Cited By ~ 10

Author(s):

Mehran Salavati ◽

Milad Tuyserkani ◽

Seyyede Anahita Mousavi ◽

Nafiseh Falahi ◽

Farshid Abdi

Keyword(s):

Risk Management ◽

Product Development ◽

New Product Development ◽

Small Sample Size ◽

New Product ◽

Small Sample ◽

Content Type ◽

Total Performance ◽

The Relationship ◽

Npd Performance

Purpose The principal aim of this study is to investigate the relationship between technological, marketing, organizational and commercialization risk management on new product development (NPD) performance. Design/methodology/approach Based on questionnaire, the data were collected from a sample of general automotive industry in Iran. Based on theoretical considerations, a model was proposed and descriptive statistic and hierarchical regression were used to measure the relationship between risk management factors and NPD performance. Findings Data analysis revealed that if organization can amplify their knowledge and information about risk and main factors that affect NPD process, not only can they do their work better but can also increase their ability to predict future happenings that affect performance. Research limitations/implications First, due to the relatively small sample size, caution should be exercised when interpreting the results. Second, the data were collected from automotive producer in Iran, which may restrict to some extent generalizability of the findings. Practical implications The results suggest that managers should consider more attention to risk management. If managers spread the risk management in all aspects of the NPD project, total performance will be increased and it can develop the probability of NPD success. Also organizations should perform great market research due to best commercialization. Originality/value Past researches have presented complete information about NPD process. But identifying and considering the effect of the risk management parameters that are connected to the NPD process were the main thrusts to perform the study. In this paper, based on past research about risk management of NPD, the extra aspect of process that can improve total performance of NPD has been examined.

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Abstract 3725: Simvastatin but Not Pravastatin Affects Sleep: Findings from the UCSD Statin Study

Circulation ◽

10.1161/circ.116.suppl_16.ii_847 ◽

2007 ◽

Vol 116 (suppl_16) ◽

Author(s):

Beatrice A Golomb ◽

Edwin K Kwon ◽

Michael H Criqui ◽

Joel E Dimsdale

Keyword(s):

Sleep Quality ◽

Rating Scale ◽

Sleep Problems ◽

Small Sample Size ◽

Case Reports ◽

Controlled Trial ◽

Small Sample ◽

T Test ◽

Secondary Outcome ◽

Regression Analyses

Background : Case reports have suggested possible effects of lipophilic statins on sleep in some subjects. Most randomized studies evaluating the effect of statins on sleep have had small sample size and short duration (≤ 6 weeks). Whether statins affect sleep on average, favorably or adversely, has been unclear. Goal : To assess the effects of lipophilic and hydrophilic statins on sleep. Subjects : 1016 adult men and women without diabetes or heart disease, with LDL-cholesterol 115–190mg/dL. Design : Randomized double blind placebo-controlled trial of simvastatin 20mg, pravastatin 40mg or placebo for 6 months. Sleep was a prespecified secondary outcome. It was assessed by both an adaptation of the Leeds sleep scale (a visual analog scale of sleep quality); and a rating scale of sleep problems. Both items were measured at baseline and on-treatment. Analysis : Baseline comparability of randomization groups including sleep measures was affirmed. T-test of mean on-treatment sleep scores across randomization groups was performed. This complemented regression analyses, adjusted for baseline values of the respective sleep assessment. Results : Groups were comparable at baseline on variables including both sleep measures. Simvastatin use was associated with significantly worse sleep quality, and significantly greater reported sleep problems than either pravastatin or placebo, by t-test and regression analyses. Pravastatin did not differ significantly from placebo on any sleep outcome. Conclusion : Findings were compatible with the hypothesis that statins may impair sleep in some subjects, and that this impairment may arise selectively with lipophilic statins. Table 1. Effects of Statins on Sleep: Regression Analysis

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CEOs’ accounting-based attributes and earnings management strategies under mandatory IFRS adoption

Journal of Applied Accounting Research ◽

10.1108/jaar-04-2017-0051 ◽

2018 ◽

Vol 19 (4) ◽

pp. 608-625 ◽

Cited By ~ 5

Author(s):

Amel Kouaib ◽

Anis Jarboui ◽

Khaireddine Mouakhar

Keyword(s):

Earnings Management ◽

Small Sample Size ◽

Small Sample ◽

Moderating Effect ◽

Audit Committees ◽

Content Type ◽

Ifrs Adoption ◽

Experience Education ◽

The Impact ◽

The Relationship

Purpose The purpose of this paper is to focus on the moderating effect of mandatory International Financial Reporting Standards (IFRS) adoption on the relationship between chief executive officer (CEO) experience/education and earnings management in European companies. Design/methodology/approach Data from a sample of 302 European firms listed on Stoxx Europe 600 index and 596 CEOs from 2000 to 2014 are used to test the moderation model using moderation regression analysis. Findings Evidence reveals that CEO’s accounting-based attributes are negatively associated with accruals-based earnings management and positively associated with real earnings management (REM). Further, mandatory IFRS adoption significantly moderates the impact of CEO’s accounting-based traits on earnings-management activities. Research limitations/implications A small number of European firms were studied and, given the long study period, many firms with missing data were eliminated. To avoid a small sample size, countries with few observations were included, which leads to an uneven distribution between observations per country. Practical implications Findings from this paper can help: European firms to consider demographic traits when recruiting or promoting executives; the IASB to improve enforcement mechanisms and make IFRS implementation mandatory; and audit committees to effectively monitor REM. Originality/value This study is unique in providing European evidence for the moderating effect of mandatory IFRS adoption on the relationship between CEOs’ accounting experience/education and earnings management activities. This paper is also relevant as it addresses the effectiveness and efficiency of accounting literates.

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Prediction of Diabetic Nephropathy from the Relationship between Fatigue, Sleep and Quality of Life

Applied Sciences ◽

10.3390/app10093282 ◽

2020 ◽

Vol 10 (9) ◽

pp. 3282

Author(s):

Angela Shin-Yu Lien ◽

Yi-Der Jiang ◽

Jia-Ling Tsai ◽

Jawl-Shan Hwang ◽

Wei-Chao Lin

Keyword(s):

Quality Of Life ◽

Feature Selection ◽

Diabetic Nephropathy ◽

Sleep Quality ◽

Support Vector ◽

Svm Classifier ◽

Poor Sleep ◽

Poor Sleep Quality ◽

The Relationship

Fatigue and poor sleep quality are the most common clinical complaints of people with diabetes mellitus (DM). These complaints are early signs of DM and are closely related to diabetic control and the presence of complications, which lead to a decline in the quality of life. Therefore, an accurate measurement of the relationship between fatigue, sleep status, and the complication of DM nephropathy could lead to a specific definition of fatigue and an appropriate medical treatment. This study recruited 307 people with Type 2 diabetes from two medical centers in Northern Taiwan through a questionnaire survey and a retrospective investigation of medical records. In an attempt to identify the related factors and accurately predict diabetic nephropathy, we applied hybrid research methods, integrated biostatistics, and feature selection methods in data mining and machine learning to compare and verify the results. Consequently, the results demonstrated that patients with diabetic nephropathy have a higher fatigue level and Charlson comorbidity index (CCI) score than without neuropathy, the presence of neuropathy leads to poor sleep quality, lower quality of life, and poor metabolism. Furthermore, by considering feature selection in selecting representative features or variables, we achieved consistence results with a support vector machine (SVM) classifier and merely ten representative factors and a prediction accuracy as high as 74% in predicting the presence of diabetic nephropathy.

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Relationship Between Sleep–Wake Disturbance and Risk of Malnutrition in Hospitalized Patients With Cirrhosis

Frontiers in Nutrition ◽

10.3389/fnut.2021.719176 ◽

2021 ◽

Vol 8 ◽

Author(s):

Yangyang Hui ◽

Xiaoyu Wang ◽

Zihan Yu ◽

Hongjuan Feng ◽

Chaoqun Li ◽

...

Keyword(s):

Sleep Quality ◽

Adverse Outcomes ◽

Nutritional Risk ◽

Poor Sleep ◽

Poor Sleep Quality ◽

Entire Cohort ◽

Related Quality ◽

Male Patients ◽

End Stage ◽

The Relationship

Both sleep–wake disturbance and malnutrition are common in cirrhosis and might be associated with similar adverse outcomes, such as impaired health-related quality of life, hepatic encephalopathy, and sarcopenia, but there is no study investigating the relationship between these two. We aimed to explore the relationship between sleep–wake disturbance [estimated by the Pittsburgh Sleep Quality Index (PSQI)] and malnutrition risk [estimated by the Royal Free Hospital-Nutritional Prioritizing Tool (RFH-NPT)]. About 150 patients with cirrhosis were prospectively recruited. The nutritional risk is classified as low (0 points), moderate (1 point), and high (2–7 points) according to the RFH-NPT score. A global PSQI >5 indicated poor sleepers. Furthermore, multivariate linear regression analyses were performed to determine the relationship between sleep–wake disturbance and malnutrition. The median PSQI was seven, and RFH-NPT was two in the entire cohort, with 60.67 and 56.67% rated as poor sleep quality and high malnutrition risk, respectively. Patients with cirrhosis with poor sleep quality had significantly higher RFH-NPT score (3 vs. 1, P = 0.007). Our multivariate analyses indicated that male patients (β = 0.279, P < 0.001), ascites (β = 0.210, P = 0.016), and PSQI (β = 0.262, P = 0.001) were independent predictors of malnutrition. In addition, the differences regarding PSQI score were more significant in male patients, as well as those >65 years or with Child-Turcotte-Pugh class A/B (CTP-A/B) or the median model for end-stage liver disease (MELD) <15. Taken together, the sleep–wake disturbance is strongly correlated with high malnutrition risk in patients with cirrhosis. Given sleep–wake disturbance is remediable, it is tempting to incorporate therapies to reverse poor sleep quality for improving nutritional status in patients with cirrhosis.

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The relationship between sleep hygiene and sleep quality among residents of an elderly care institution in DKI Jakarta

UI Proceedings on Health and Medicine ◽

10.7454/uiphm.v4i1.258 ◽

2020 ◽

Vol 4 (1) ◽

Author(s):

Mutia Annisa ◽

Dwi Nurviyandari Kusuma Wati

Keyword(s):

Sleep Quality ◽

Sleep Problems ◽

Elderly Care ◽

Sleep Hygiene ◽

Poor Sleep ◽

Poor Sleep Quality ◽

Cross Sectional ◽

Cross Sectional Design ◽

The Relationship ◽

Purposive Sample

Objective: Elderly are at risk of poor slepp quality and other health problems due to reduced sleep satisfaction. The objective of this study was to explore the association between sleep hygiene and sleep quality in elderly.Methods: This was a descriptive study with cross sectional design. The study was conducted in four elderly care institutions in Jakarta, Indonesia, involving a purposive sample of 103 elderly aged 60 to 111 years old. Data were collected using Sleep Hygiene Index (SHI) and Pittsburgh Sleep Quality Index (PSQI).Results: Over half of the residents had poor sleep hygiene (51.5%) and more than three quarter (81.6%) had poor sleep quality. The study revealed that there was a highly significant relationship between sleep hygiene and sleep quality (p = 0.001). The study also showed that those with poor sleep hygiene were 7.834 times more likely to have poor sleep quality.Conclusion: Nurses need to include interventions that may address residents’ sleep problems. They also need to promote sleep hygiene and improve residents’ sleep quality.Keywords: elderly, institution, sleep hygiene, sleep quality

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