ROLE OF NUTRITION IN MAINTAINING NORMAL EYESIGHT-A REVIEW

The eye is particularly susceptible to oxidative stress as a result of its high oxygen consumption, high concentration of polyunsaturated fatty acids and cumulative exposure to high-energy visible light. This combination of factors leads to the generation of reactive oxygen species that can trigger oxidative damage to ocular tissues. There is evidence that the human consumer should avoid excessive supplementation with carotenoids. Poly-unsaturated fatty acids are linked to eye disease (as well as multiple other chronic diseases) in both positive and negative ways. Dietary poly-unsaturated fatty acids fall into two major groups, i.e., omega-6 (mainly linoleic acid and arachidonic acid) and omega-3 fatty acids, mainly alpha-linolenic acid, eicosapentaenoicacid (EPA) and docosahexaenoic acid (DHA). Vitamin A deficiency is rare in the United States, but it is common among the poor in developing countries. It's estimated that approximately 250,000 to 500,000 malnourished children worldwide become blind each year due to vitamin A deficiency that could have been prevented with a proper diet. A lack of vitamin A causes the cornea to become very dry, leading to clouding of the front of the eye, corneal ulcers and vision loss. Vitamin A deficiency also causes damage to the retina, which also contributes to blindness. Keywords: Vitamin A, DHA, Glaucoma, retinopathy

Download Full-text

250 Evaluation of Green Grass as a feed ingredient in beef finishing rations and impact on cattle performance, carcass characteristics, and fatty acid profiles in meat

Journal of Animal Science ◽

10.1093/jas/skaa054.240 ◽

2020 ◽

Vol 98 (Supplement_3) ◽

pp. 138-138

Author(s):

Mitchell M Norman ◽

Nicolas Bland ◽

Bradley M Boyd ◽

Brianna Conroy ◽

Chris Calkins ◽

...

Keyword(s):

Fatty Acids ◽

Fatty Acid ◽

Unsaturated Fatty Acids ◽

Carcass Characteristics ◽

Omega 3 Fatty Acids ◽

Fatty Acid Profiles ◽

Omega 3 ◽

Alpha Linolenic Acid ◽

Marbling Score ◽

Finishing Diets

Abstract A finishing study used 240 crossbred steers (initial BW=340 ±24 kg) to evaluate performance, carcass characteristics, and fatty acid profiles of beef from finishing steers. Four inclusions (0, 10, 20, 30 % DM basis) of Green Grass displaced dry rolled corn in the finishing diet. Green Grass is a blend of herbs and plants imported from Korea that are high in omega-3 fatty acids with 13.9 % fat,32.0 % CP, and 27.0 % Acid detergent fiber. The remaining diet consisted of 15 % WDGS, 20 % corn silage, and 6 % liquid supplement (DM basis). There were no differences in final BW, gain or carcass traits (P³0.14). Cattle were harvested over three slaughter days and were fed for 190, 199, or 203 days. Dry matter intake linearly increased (P = 0.04)as Green Grass inclusion increased in the diet. A linear response (P£0.01) to feeding Green Grass was observed for G:F, with steers fed Green Grass having lower feed efficiency than control cattle. The G:F of cattle fed Green Grass was 5.4, 3.4, and 6.8 % lower in G:F as inclusion increased suggesting Green Grass has 68.6 % the energy of corn it replaced. Steers fed 30 % Green Grass had a lower marbling score. Linear increases in alpha linolenic acid, trans-unsaturated fatty acids, and omega-3 fatty acids (P£0.01) were observed in steak samples from steers fed increasing inclusion of Green Grass. Including up to 30 % inclusion of Green Grass on a DM basis in finishing diets decreased G:F; however, it appeared to have no other effects on performance or carcass characteristics. Feeding Green Grass linearly improved omega-3 fatty acid concentration in beef.

Download Full-text

DEVELOPMENT OF AN EXPERIMENTAL MODEL OF AVITAMINOSIS F

Grain Products and Mixed Fodder’s ◽

10.15673/gpmf.v20i2.1764 ◽

2020 ◽

Vol 20 (2) ◽

pp. 38-40

Author(s):

A. Levitsky ◽

A. Lapinska ◽

I. Selivanskaya

Keyword(s):

Fatty Acids ◽

Experimental Model ◽

Unsaturated Fatty Acids ◽

Saturated Fatty Acids ◽

Coconut Oil ◽

The Body ◽

Regulatory Function ◽

Omega 3 ◽

White Rats ◽

Arachidonic Acids

The article analyzes the role of essential polyunsaturated fatty acids (PUFA), especially omega-3 series in humans and animals. The biosynthesis of essential PUFA in humans and animals is very limited, so they must be consumed with food (feed). Тhe ratio of omega-3 and omega-6 PUFA is very important. Biomembranes of animal cells contain about 30% PUFA with a ratio of ω-6/ ω-3 1-2. As this ratio increases, the physicochemical properties of biomembranes and the functional activity of their receptors change. The regulatory function of essential PUFA is that in the body under the action of oxygenase enzymes (cyclooxygenase, lipoxygenase) are formed extremely active hormone-like substances (eicosanoids and docosanoids), which affect a number of physiological processes: inflammation, immunity, metabolism. Moreover, ω-6 PUFA form eicosanoids, which have pro-inflammatory, immunosuppressive properties, and ω-3 PUFAs form eicosanoids and docosanoids, which have anti-inflammatory and immunostimulatory properties. Deficiency of essential PUFA, and especially ω-3 PUFA, leads to impaired development of the body and its state of health, which are manifestations of avitaminosis F. Prevention and treatment of avitaminosis F is carried out with drugs that contain PUFA. To create new, more effective vitamin F preparations, it is necessary to reproduce the model of vitamin F deficiency. An experimental model of vitamin F deficiency in white rats kept on a fat –free diet with the addition of coconut oil, which is almost completely free of unsaturated fatty acids, and saturated fatty acids make up almost 99 % of all fatty acids was developed. The total content of ω-6 PUFA (sum of linoleic and arachidonic acids), the content of ω-3 PUFA (α-linolenic, eicosapentaenoic and docosahexaenoic acids) in neutral lipids (triglycerides and cholesterol esters) defined. Тhe content of ω-6 PUFA under the influence of coconut oil decreased by 3.3 times, and the content of ω-3 PUFA - by 7.5 times. Тhe influence of coconut oil, the content of ω-6 PUFA decreased by 2.1 times, and the content of ω-3 PUFA - by 2.8 times. The most strongly reduces the content of ω-3 PUFA, namely eicosapentaenoic, coconut oil, starting from 5 %. Consumption of FFD with a content of 15 % coconut oil reduces the content of eicosapentaenoic acid to zero, ie we have an absolute deficiency of one of the most important essential PUFAs, which determined the presence of vitamin F deficiency.

Download Full-text

EFFECT OF GINGER, LEMURU FISH OIL SAPONIFICATION AND OLIVE OIL ON COMPOSITION FATTY ACID OF BEEF

Jurnal Agroindustri ◽

10.31186/j.agroind.4.1.31-39 ◽

2014 ◽

Vol 4 (1) ◽

pp. 31-39

Author(s):

Siwitri Kadarsih

Keyword(s):

Fatty Acids ◽

Fatty Acid ◽

Fish Oil ◽

Olive Oil ◽

Rice Bran ◽

Dry Matter ◽

Unsaturated Fatty Acids ◽

Saturated Fatty Acids ◽

Omega 3 ◽

Omega 6

The objective was to get beef that contain unsaturated fatty acids (especially omega 3 and 6), so as to improve intelligence, physical health for those who consume. The study design using CRD with 3 treatments, each treatment used 4 Bali cattle aged approximately 1.5 years. Observations were made 8 weeks. Pasta mixed with ginger provided konsentrat. P1 (control); P2 (6% saponification lemuru fish oil, olive oil 1%; rice bran: 37.30%; corn: 62.70%; KLK: 7%, ginger paste: 100 g); P3 (lemuru fish oil saponification 8%, 2% olive oil; rice bran; 37.30; corn: 62.70%; KLK: 7%, ginger paste: 200 g). Konsentrat given in the morning as much as 1% of the weight of the cattle based on dry matter, while the grass given a minimum of 10% of the weight of livestock observation variables include: fatty acid composition of meat. Data the analyzies qualitative. The results of the study showed that the composition of saturated fatty acids in meat decreased and an increase in unsaturated fatty acids, namely linoleic acid (omega 6) and linolenic acid (omega 3), and deikosapenta deikosaheksa acid.Keywords :

Download Full-text

Drug Therapy for Abdominal Aortic Aneurysms Utilizing Omega-3 Unsaturated Fatty Acids and Their Derivatives

Current Drug Targets ◽

10.2174/1389450118666171013101815 ◽

2018 ◽

Vol 19 (11) ◽

pp. 1309-1317 ◽

Cited By ~ 2

Author(s):

Daisuke Akagi ◽

Katsuyuki Hoshina ◽

Toshiaki Watanabe ◽

Micheal S. Conte

Keyword(s):

Fatty Acids ◽

Drug Therapy ◽

Unsaturated Fatty Acids ◽

Abdominal Aortic Aneurysms ◽

Aortic Aneurysms ◽

Omega 3 ◽

Abdominal Aortic

Download Full-text

Food-Based Dietary Guidelines for Seafood Do Not Translate into Increased Long-Chain Omega-3 Levels in the Diet for U.S. Consumers

Foods ◽

10.3390/foods10081816 ◽

2021 ◽

Vol 10 (8) ◽

pp. 1816

Author(s):

Michael F. Tlusty

Keyword(s):

United States ◽

Fatty Acids ◽

National Level ◽

The United States ◽

Dietary Guidelines ◽

Omega 3 Fatty Acids ◽

Omega 3 ◽

Complete Understanding ◽

The U.S ◽

Long Chain

Humans under-consume fish, especially species high in long-chain omega-3 fatty acids. Food-based dietary guidelines are one means for nations to encourage the consumption of healthy, nutritious food. Here, associations between dietary omega-3 consumption and food-based dietary guidelines, gross domestic product, the ranked price of fish, and the proportions of marine fish available at a national level were assessed. Minor associations were found between consumption and variables, except for food-based dietary guidelines, where calling out seafood in FBDGs did not associate with greater consumption. This relationship was explored for consumers in the United States, and it was observed that the predominant seafood they ate, shrimp, resulted in little benefit for dietary omega-3 consumption. Seafood is listed under the protein category in the U.S. Dietary Guidelines, and aggregating seafood under this category may limit a more complete understanding of its nutrient benefits beyond protein.

Download Full-text

Serum long chain omega-3 fatty acids and depression among adults in the United States: An analysis of NHANES 2011–2012

Journal of Affective Disorders Reports ◽

10.1016/j.jadr.2021.100089 ◽

2021 ◽

Vol 4 ◽

pp. 100089

Author(s):

Rachel A Murphy ◽

Prasad P. Devarshi ◽

Shauna Ekimura ◽

Keri Marshall ◽

Susan Hazels Mitmesser

Keyword(s):

United States ◽

Fatty Acids ◽

The United States ◽

Omega 3 Fatty Acids ◽

Omega 3 ◽

Long Chain

Download Full-text

The Fatty Acid Profile in Patients with Newly Diagnosed Diabetes: Why It Could Be Unsuspected

International Journal of Pediatrics ◽

10.1155/2017/6424186 ◽

2017 ◽

Vol 2017 ◽

pp. 1-5 ◽

Cited By ~ 3

Author(s):

C. Castro-Correia ◽

S. Sousa ◽

S. Norberto ◽

C. Matos ◽

V. F. Domingues ◽

...

Keyword(s):

Fatty Acids ◽

Fatty Acid ◽

Control Group ◽

Healthy Children ◽

Omega 3 ◽

Alpha Linolenic Acid ◽

Diabetes Group ◽

Diabetic Children ◽

Omega 6 ◽

Diagnosed Diabetes

Context. Several studies have shown a link between proinflammatory activity and the presence or deficit of some fatty acids. Inflammation is associated with several diseases including diabetes.Objective. To characterize and compare the fatty acids profiles in children with inaugural type 1 diabetes, diabetic children (at least 1 year after diagnosis), and healthy children.Design. Plasma fatty acids profiles in children with inaugural diabetes, children with noninaugural diabetes, and controls, all of whom were prepubescent with a BMI < 85th percentile, were evaluated.Results. Omega-3 fatty acid levels were higher in recently diagnosed subjects with diabetes than in controls. The ratio of omega-6/omega-3 fatty acids was higher in the control population. Omega-6 fatty acid levels were higher in the nonrecent diabetic subjects than in the children with recently diagnosed diabetes, and the levels were higher in the nonrecent diabetes group compared to the control group.Conclusion. Our findings showed higher levels of alpha-linolenic acid, EPA, and DHA, as well as mono- and polyunsaturated fatty acids, in diabetic children. These findings reinforce the importance of precocious nutritional attention and intervention in the treatment of diabetic children.

Download Full-text

Eicosapentaenoic Acid Is Associated with Decreased Incidence of Alzheimer’s Dementia in the Oldest Old

Nutrients ◽

10.3390/nu13020461 ◽

2021 ◽

Vol 13 (2) ◽

pp. 461

Author(s):

Debora Melo van Lent ◽

Sarah Egert ◽

Steffen Wolfsgruber ◽

Luca Kleineidam ◽

Leonie Weinhold ◽

...

Keyword(s):

Fatty Acids ◽

Eicosapentaenoic Acid ◽

Linolenic Acid ◽

Oldest Old ◽

Omega 3 ◽

Alpha Linolenic Acid ◽

Multicenter Cohort Study ◽

Cognitive Health ◽

Apoe Ε4 ◽

Serum Phospholipids

Background. Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) may have different effects on cognitive health due to their anti- or pro-inflammatory properties. Methods. We aimed to prospectively examine the relationships between n-3 and n-6 PUFA contents in serum phospholipids with incident all-cause dementia and Alzheimer’s disease dementia (AD). We included 1264 non-demented participants aged 84 ± 3 years from the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe) multicenter-cohort study. We investigated whether fatty acid concentrations in serum phospholipids, especially eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), alpha-linolenic acid (ALA), linoleic acid (LA), dihomo-γ-linolenic acid (DGLA), and arachidonic acid (AA), were associated with risk of incident all-cause dementia and AD. Results. During the follow-up window of seven years, 233 participants developed dementia. Higher concentrations of EPA were associated with a lower incidence of AD (hazard ratio (HR) 0.76 (95% CI 0.63; 0.93)). We also observed that higher concentrations of EPA were associated with a decreased risk for all-cause dementia (HR 0.76 (95% CI 0.61; 0.94)) and AD (HR 0.66 (95% CI 0.51; 0.85)) among apolipoprotein E ε4 (APOE ε4) non-carriers but not among APOE ε4 carriers. No other fatty acids were significantly associated with AD or dementia. Conclusions. Higher concentrations of EPA were associated with a lower risk of incident AD. This further supports a beneficial role of n-3 PUFAs for cognitive health in old age.

Download Full-text

Perilla frutescens: a potential ingredient for the enhancement of white bread as a source of Omega-3

Acta Scientiarum Technology ◽

10.4025/actascitechnol.v38i4.27436 ◽

2016 ◽

Vol 38 (4) ◽

pp. 399

Author(s):

Marcos Vieira da Silva ◽

Andréia Vieira da Silva ◽

Elton Guntendorfer Bonafé ◽

Nilson Evelázio de Souza ◽

Jesuí Vergílio Visentainer

Keyword(s):

Fatty Acids ◽

Daily Intake ◽

Perilla Frutescens ◽

White Bread ◽

Omega 3 Fatty Acids ◽

Adult Males ◽

Omega 3 ◽

Alpha Linolenic Acid ◽

Males And Females ◽

Sensorial Attributes

Perilla frutescens seeds are rich in Omega-3 fatty acids which are important for human health. Intake of fatty acids depends on their presence in popular foods such as white bread. Current study evaluates the replacement of wheat flour by whole perilla at 1, 3 and 5% in white bread processing and its impacts on chemical and sensorial attributes, underscoring Omega-3 amounts. The use of whole perilla increases the Omega-3 content in white bread, balances the ratio n-6/n-3, decreases the specific volume, and maintains the concentration of phenolic compounds and antioxidant activity. The formulation with 1% whole perilla has a better acceptability and supplies 5.63 and 8.19% of the American recommended daily intake of alpha-linolenic acid for adult males and females, respectively.

Download Full-text