scholarly journals THE EFFECT OF MELON SEEDS FLOUR (Cucumis Melo L.) TOWARD TOTAL CHOLESTEROL LEVEL IN WHITE MALE WISTAR STRAIN RATS (Rattus Norvegicus)

2018 ◽  
Vol 12 (2) ◽  
pp. 151
Author(s):  
Maruni Wiwin Diarti ◽  
Erlin Yustin Tatontos ◽  
Yunan Jiwintarum ◽  
Anggun Sari Mianti
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Cucumis Melo ◽  
Total Cholesterol Level ◽  
White Male ◽  
The Body ◽  
Male Rats ◽  
Wistar Strain ◽  
Melon Seeds ◽  
Cucumis Melo L

Abstract: Cholesterol is an important element in the body, but in high quantities, it can cause atherosclerosis that will eventually possess an impact on coronary heart disease. One of the foods that can reduce cholesterol is a food contains flavonoids which is found in melon seeds (Cucumis melo l.). It contains high fiber that can reduce either of excessive insulin or blood fat levels. The objective study was to determine the effect of Melon seeds flour Toward Total Cholesterol Level in White Male Wistar Strain Rats. This research was carried out with pre-expriment research design, used One group pretest-postest with 5 male wistar strain rats. Data collected in the form of data examination results of total cholesterol level before and after introducing Melon seeds flour. The mean result of total cholesterol test in white male rats before giving Melon seeds flour was 261 mg / dL, whereas the result of total cholesterol test after giving Melon seeds flour was 190.2 mg/dL. Cholesterol levels decreased by 70.8 mg/dl. In short, presenting Melon seeds flour (Cucumis melo l.) for 14 days can decrease total cholesterol level in white male wistar rats. Keywords: Melon Seeds, wistar strain, total cholesterol.

scholarly journals The Comparison of Total Cholesterol Level in DMPA and Combination Injection Contraception Users

2020 ◽  
Vol 6 (2) ◽  
pp. 117
Author(s):  
Rara Yumna Elfrida ◽  
Gadis Meinar Sari ◽  
Sri Ratna Dwiningsih ◽  
Pudji Lestari
Keyword(s):  
Side Effects ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Sampling Technique ◽  
The Body ◽  
Bivariate Analysis ◽  
Cross Sectional ◽  
Cholesterol Levels ◽  
Hormonal Content

Introduction: Hormonal injection contraception is the most widely used method of contraception in Indonesia. In long-term use, one of the side effects of injection contraception is changes in lipid metabolism in the body caused by the accumulation of hormones in the body. Two types of injectional contraception are widely used in Indonesia, namely combined injection and DMPA injection; different hormonal content has various side effects on the lipid profile. This study aimed to compare the total cholesterol level between acceptors of DMPA injection and combined injection.Methods: This study used an observational analytic method with a cross-sectional approach. The sample size is 60 respondents, including 30 DMPA injection acceptors and 30 combination injection acceptors. The sampling method uses a purposive sampling technique The independent variable in this study was the total cholesterol level of the acceptor, and the dependent variable was the acceptor of DMPA injection and the combination injection acceptor. Analysis of research data used the Independent T-test with α=0.05.Results: The results of the bivariate analysis found significant differences in total cholesterol levels in the DMPA injection contraception acceptor and combination injection with p= 0.037. It was found that overall cholesterol levels of DMPA injection acceptors were higher.Conclusion: There is a difference in total cholesterol levels in the DMPA injection contraception acceptor with a combination injection contraception acceptor.

scholarly journals PENGARUH PEMBERIAN EKSTRAK PEPAYA TERHADAP KADAR KOLESTEROL TOTAL, LDL DAN HDL DARAH TIKUS PUTIH JANTAN HIPERKOLESTEROLEMIA

2012 ◽  
Vol 36 (1) ◽  
pp. 29 ◽  
Author(s):  
Endrinaldi Endrinaldi ◽  
Asterina Asterina
Keyword(s):  
Total Cholesterol ◽  
Bile Acids ◽  
White Male ◽  
Serum Levels ◽  
The Body ◽  
Water Soluble ◽  
Male Rats ◽  
Intestinal Lumen ◽  
Control Group ◽  
Soluble Fiber

AbstrakPepaya mengandung pektin yang merupakan serat larut air. Pektin berkemampuan mengikat asam empedu dan dieliminasi keluar tubuh melalui feses. Penurunan jumlah asam empedu di lumen usus menyebabkan hepar menggunakan kolesterol dalam darah untuk membentuk asam empedu. Hal tersebut mengakibatkan penurunan jumlah kolesterol.Tujuan studi ini adalah untuk melihat pengaruh pemberian ekstrak pepaya mengkal terhadap kadar kolesterol total, HDL dan LDL tikus putih. Desain penelitian ini adalah eksperimental menggunakan 20 ekor tikus putih jantan yang dibagi menjadi empat kelompok, yaitu kelompok kontrol, dan kelompok perlakuan dengan pemberian ekstrak pepaya dengan dosis 0,5 ml, 1 ml dan 1,5 ml per 200g/BB melalui oral selama 15 hari.Hasil penelitian menunjukkan terjadinya penurunan rerata kadar kolesterol total, LDL, dan peningkatan kadar HDL serum tikus setelah pemberian ekstrak pepaya selama 15 hari secara bermakna (p<0,05). Tetapi tidak terjadi perbedaan yang bermakna (p>0,05) antara kelompok yang diberi ekstrak pepaya dengan dosis 0,5 ml, 1 ml, dan 1,5 ml.Kesimpulan yang dapat diambil dari studi ini ialah bahwa ekstrak pepaya dapat menurunkan kadar kolesterol total, LDL, dan peningkatan kadar HDL pada serum tikus putih jantanKata kunci : pektin, kolesterol, asam empedu, serat, tikus.AbstractPapaya contain pectin which is a water-soluble fiber. Pectin has the ablity to bind bile acids and eliminated out of the body through the feces. Decrease in the amount of bile acids in intestinal lumen causing liver uses cholesterol to synthesize bile acids blood.The purpose of this study was to see the effect of papaya extract on total cholesterol, HDL and LDL of male rats. This is an experimental research design using 20 white male rats were divided into four groups : control group and group treated with papaya extract a dose of 0,5 ml, 1 ml per 200 gr/body weight orally for 15 days.Results showed a decrease in everage total cholesterol, LDL and increased serum levels of rats after administration of papaya extract after 15 days wereARTIKEL PENELITIAN30significantly (p<0,05). But no significantly difference occused (p>0,05) between groups were fed papaya extractat a dose of 0,5 ml, 1 ml and 1,5 ml.Conclusions from the study are that papaya extract can lower total cholesterol, LDL and levels increased in the serum of male ratsKey word : pectin, cholesterol, bile acid, fiber, rats.

scholarly journals Efektivitas Nasi Beras, Merah (Oryza Nivara) Terhadap Kadar Kolesterol Total Penderita Diperkolesterolemia

Jurnal GIZIDO ◽  
2019 ◽  
Vol 11 (01) ◽  
pp. 1-7
Author(s):  
Nonce Nova Legi ◽  
Mirna Kawulusan ◽  
Marstevi Olivia Gedoan
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Brown Rice ◽  
The Body ◽  
Water Soluble ◽  
Soluble Fiber ◽  
Oryza Nivara ◽  
Cholesterol Levels ◽  
Before And After

Hypercholesterolemia is an increase in total cholesterol levels in the blood beyond the normal limits. Excess cholesterol levels in the blood will have an impact on degenerative diseases. Brown rice (oryza nivara) is a rice rich in vitamins, minerals and contain water soluble fiber that can help bind cholesterol, then throw it out of the body. Regular consumption of brown rice is very beneficial for health that can reduce levels of LDL. The aim of this research is to know the effectiveness of brown rice rice to total cholesterol level in hypercholesterolemia patient in Vilage Sea Pineleng District of Minahasa Regency. The type of this research is Quasi Eksperimen with One Group of Pretest and Posttest Design. The sample in this study is the entire population of hypercholesterolemia patients recorded in Posbindu Village Sea Pineleng District Minahasa regency that meets the inclusion criteria. Rice brown rice is given for 8 consecutive days every morning, day and night. Total cholesterol levels were measured before and after administration of brown rice. Data analysis using Paired t-test. The results showed that the total cholesterol level before the study was the highest of 360 mg / dl, the lowest was 216 mg / dl, and after the highest total cholesterol was 298 mg / dl, the lowest was 164 mg / dl. The result of statistical test shows that p = 0,019 (p <0,05), which means that there is difference of total cholesterol before and after giving of rice of red rice to hypercholesterolemia patient in Vilage Sea Pineleng Sub-district of Minahasa Regency.

ANTIDIABETIC ACTIVITY OF METHANOLIC EXTRACT OF CUCUMIS DIPSACEUS EHRENB. (FRUIT) IN STREPTOZOTOCIN- INDUCED DIABETIC RATS

INDIAN DRUGS ◽  
2019 ◽  
Vol 56 (12) ◽  
pp. 53-61
Author(s):  
Gagandeep Kaur ◽  
◽  
D. Srivastav ◽  
Suman Lata
Keyword(s):  
Blood Glucose ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Methanolic Extract ◽  
Total Cholesterol Level ◽  
Serum Insulin ◽  
Glycosylated Hemoglobin ◽  
Diabetic Rats ◽  
The Body ◽  
Antidiabetic Activity

The present study was designed to investigate the hypoglycemic and antidiabetic properties of Cucumis dipsaceus fruit which is widely used in the Indian traditional medicine for the treatment of diabetes.Aim of present study, to investigate the antidiabetic action of the methanolic extract of C. dipsaceus fruits in Streptozotocin induced-diabetic rats. The antidiabetic activity of methanolic extract of fruit C. dipsaceus was evaluated by using normal and streptozotocin induced-diabetic rats. The acute effect of methanolic extract was evaluated by administering 500 mg/kg p.o. to normoglycemic rats. In the chronic model, the methanolic extract was administered to normal and STZ-induced-diabetic rats at dose of 250 mg/kg and 500 mg/kg p.o. per day for 21 days. Blood glucose levels and body weights were observed at specific intervals and different biochemical parameters were also monitored. Methanolic extract (500mg/kg) produced a significant reduction in blood glucose level in STZ- induced diabetic rats. The statistical data indicated a significant increase in the body weight and serum insulin level and decrease in the glycosylated hemoglobin levels. Total cholesterol level decreased while an increase in HDL and LDL cholesterol level was observed when treated with the extract. Thus the methanolic fruit extract of C. dipsaceus exhibited significant anti-hyperglycemic activities and beneficial effects in reducing the elevated total cholesterol level of STZ-induced-diabetic rats.

scholarly journals Prevention of Increasing Total Cholesterol Level Using Cowpea Yoghurt

2020 ◽  
Vol 3 (1) ◽  
pp. 38
Author(s):  
Maulana Rahmat Hidayatullah
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Lipoprotein Metabolism ◽  
Male Rats ◽  
Control Group ◽  
Control Group Design ◽  
Metabolism Disorder ◽  
Significant Difference ◽  
Coa Reductase

Atherosclerosis is lipoprotein metabolism disorder which is marked by an increase of total cholesterol level in blood serum. Cowpea contains a lot of isoflavones that can inhibit the activity of the enzyme HMG-CoA reductase in the cholesterologenesis process. The aim of this study is to find out cowpea yogurt which can prevent the increasing total cholesterol level. This study used an experimental study with a post-test only control group design in 30 male rats. It was divided into 5 groups: Results showed that the total cholesterol level among the fifth group was a significant difference (Kruskal-Wallis, p = 0,000). The conclusion of this study is cowpea yogurt can prevent the increasing total cholesterol levels of Wistar rats induced by a high-fat diet.

scholarly journals Effectiveness of Ficus Elastica Roxb. Ex Hornem Leaf Extract in Reducing Total Cholesterol Level in High Fat Induced Diet Wistar Male Rats

2020 ◽  
Author(s):  
Muhamad Seto Sudirman ◽  
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Ethanol Extract ◽  
Study Groups ◽  
Male Rats ◽  
Plant Metabolites ◽  
Quasi Experimental ◽  
Mean Differences ◽  
Biology Laboratory

ABSTRACT Background: Kebo rubber leaves (ficus elastica roxb) contain flavonoids, polyphenols, and tannins. Flavonoids in the leaves of ficus elastica roxb such as catechins, isoflavones are polyphenolic antioxidants from plant metabolites. The leaves of ficus elastica roxb are trusted and proven empirically in the community to reduce cholesterol levels in the blood. Mice choose animals because they are considered to have physiological similarities with humans. This study aimed to determine the effect of ethanol extract of ficus elastica roxb leaves on reducing total cholesterol level in male Swiss Webster mice. Subjects and Method: This was a quasi-experimental study conducted at Biology Laboratory of the Faculty of Agriculture, Fisheries and Biology, University of Bangka Belitung from April to June, 2017. A sample of 25 male Swiss Webster mice was selected at random and allocated into groups. The dependent variable was total cholesterol. The independent variable was the extract of ficus elastica rox. The data were tested by One-Way ANOVA. Result: There were statistically significant mean differences among the study groups (p= 0.002), indicating the effect of ethanol extract of Ficus Elastica Roxb leaves on reducing total cholesterol level in male Swiss Webster mice at various doses. Conclusion: There are statistically significant mean differences among the study groups, indicating the effect of ethanol extract of Ficus Elastica Roxb leaves on reducing total cholesterol level in male Swiss Webster mice at various doses. Keyword: Ethanol extract of Ficus Elastica Roxb leaves, total cholesterol, mice Correspondence: Muhamad Seto Sudirman. School of Health Polytechnic, Pangkalpinang. Email: [email protected] DOI: https://doi.org/10.26911/the7thicph.05.10

The Study of the Body Structure and Total Cholesterol Level Dependence on the Type of Evolutive Constitution of Second Adulthood Men

2014 ◽  
pp. 95-99
Author(s):  
Olga Filatova ◽  
Alexandra Ledinа ◽  
Elena Vorobyovа ◽  
Anna Kazyzaeva ◽  
Galina Sokolova ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
The Body ◽  
Body Structure

Pengaruh Pemberian Terapi Oksigen Hiperbarik Terhadap Kadar Kolesterol Total Pada Tikus Putih (Rattus novergicus) Jantan Galur Wistar Yang Di Induksi Diet Tinggi Lemak

2018 ◽  
Vol 16 (1) ◽  
pp. 1 ◽  
Author(s):  
AZRUL HILDAN SAFRIZAL
Keyword(s):  
Cardiovascular Disease ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
High Fat Diet ◽  
Oxygen Therapy ◽  
Total Cholesterol Level ◽  
High Fat ◽  
Cholesterol Levels

<p>The pattern and lifestyle of today's society with the presence of an interner facility makes people spend more time sitting out than on exercise and increased consumption of high-fat foods may increase the risk of cardiovascular disease. An effective therapy is needed in preventing the occurrence of cardiovascular disease. Hyperbaric oxygen now starts to develop for the treatment of several diseases, which in turn can increase the gene forming antioxidant enzymes and ROS. To determine effect of hyperbaric oxygen therapy on total cholesterol levels of wistar white rats (Rattusnovergicus) induced bye high fat. The study was carried out in an expeative post test only group control of three groups. One group is given standard feed. All groups induced high-fat diet and standard feed. Of the two groups induced, one group was given hyperbaric oxygen therapy with a dose of 3 x 30 minutes for six days on day 7 at a blood test to determine total cholesterol levels<strong>. </strong>One way Anova parametric statistic test showed that p = 0.007 &lt; α proved hypothesis that hyperbaric oxygen therapy giving effect to total cholesterol level of white mice of jantangalurist rings induced by high fat diet. Total cholesterol was significantly different between K (-) and K (+) and between K (-) and P. It was found that hyperbaric oxygen therapy had an effect on total cholesterol level dose of 3x30 minutes for six days.</p>

Tracking of Serum Cholesterol Levels in a Multiracial Sample of Preschool Children

PEDIATRICS ◽  
1992 ◽  
Vol 90 (1) ◽  
pp. 80-86 ◽  
Author(s):  
David S. Freedman ◽  
Tim Byers ◽  
Karen Sell ◽  
Sarah Kuester ◽  
Eva Newe1l ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Initial Level ◽  
Total Cholesterol Level ◽  
Relative Weight ◽  
Cholesterol Levels ◽  
Final Measurement ◽  
Subsequent Measurement ◽  
Initial Measurement

The relation of an initial measurement of serum total cholesterol to subsequent levels over a (mean) 13-month interval was examined in a multiracial (white, Hispanic, American Indian, and black) sample of 1680 one- to four-year-olds. Although the relation of the initial level to the final measurement (r = .54) did not vary by race, sex, relative weight, or changes in relative weight, the association increased with age at the time of the initial measurement (eg, r .64 among 4-year-olds). Based on the initial and final total cholesterol determinations, the within-person standard deviation was 21 mg/dL and the coefficient of variation was 13%. Although the final total cholesterol level was within 5 mg/dL of the initial level for 18% of the children, the two determinations differed by ≥25 mg/dL for about 35% of the children and by ≥50 mg/dL for about 8%. Of the 149 children who had an initial cholesterol level ≥200 mg/dL, 34% (about five times the expected number) had a follow-up level that was similarly elevated whereas 25% had a subsequent measurement below 170 mg/dL. The results indicate that although an initial cholesterol level in early life is moderately predictive of subsequent levels, it may be difficult to interpret a single total cholesterol determination because of substantial within-person variability.

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