scholarly journals Prediction of Length of Hospital Stay and Immediate Outcome of Children Suffering From Bronchiolitis on the Bases of Associated Risk Factors

2021 ◽  
Vol 7 (2) ◽  
pp. 67-71
Author(s):  
Bithi Debnath ◽  
Sajani Islam ◽  
Nazmul Haque
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Hospital Stay ◽  
Previous History ◽  
Length Of Hospital Stay ◽  
Wood Burning ◽  
History Of ◽  
Male Sex ◽  
Associated Risk Factors ◽  
Length Of Hospitalization

Background: Bronchiolitis is the most common reason for hospitalization among children younger than 2 years. Objective: The aim of the study was to assess the possibility that the associated risk factors in children suffering from bronchiolitis could predict the length of hospital stay and also to observe the immediate outcome. Methodology: This prospective study was conducted in a district hospital of Bangladesh in a period of two years from January 2011 to December 2012. Patients aged 2 years or less fulfilling inclusion criteria for bronchiolitis and required admission were enrolled in this study. Patients having comorbidities and who were discharged before fulfilling the study criteria for discharge were excluded from the study. Treatment was given according to National Guidelines for the Management of Bronchiolitis. All demographic, clinical and laboratory data were recorded in a prefixed questionnaire and analyzed. Results: Among 100 patients, 60% cases were hospitalized for 4 days or more. Mean duration of hospital stay was 4.37±1.93 days. Patients of male sex (67%), younger than 6 months of age (71%), preterm birth (21%), weight-for-age was either ≥2SD (60%) or ≤3SD (23%) were hospitalized for longer duration. Length of hospitalization was also increased in patients with family history of asthma (37%), smoking (75%), using wood-burning stoves for cooking (89%) and no previous history of respiratory distress (81%). Exclusively breastfed infants (41%) stayed hospital for shorter duration than those who fed partially (53%) or not at all (6%). All patients were improved in this case series (100%). Conclusion: Bronchiolitis patients having male sex, age less than 6 months, preterm born, partially breast fed , family history of asthma, exposure to smoking and wood-burning stoves were deduced to be significant risk factors for prolongation of length of hospitalization. Further research is needed to determine how these risk factors contribute to the development of the disease and prolong the length of hospital stay. Bangladesh Journal of Infectious Diseases 2020;7(2):67-71

scholarly journals Study on Associated Risk Factors of Hypertension at Sipaghat of Sindhupalchowk District, Nepal

2017 ◽  
Vol 1 ◽  
pp. 73-82
Author(s):  
Naresh Manandhar
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Alcohol Consumption ◽  
Lifestyle Modification ◽  
Percent Level ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
History Of ◽  
Family History Of Hypertension ◽  
Associated Risk Factors

Background: Hypertension is a progressive cardiovascular syndrome arising from complex and interrelated etiologies. Males have slightly higher prevalence than female in most of countries of Southeast-Asian region.Objective: The objective of study is to find out prevalence and the risk factors of hypertension at Sipaghat, Sindhulchowk, Nepal.Materials and Methods: A cross-sectional study was conducted at Sipaghat of Sindhupalchowk district in May 2016 and 260 persons were selected randomly. Results: The prevalence of hypertension was higher in male (25.4%) than female (17.4%). Mean age of study population was 42.08 years with standard deviation, 15.95 years. Variables namely age group, smoking, alcohol consumption and family history of hypertension were found to be significant at 5 percent level of significance. Alcohol consumption and smokers have more than two times higher chance of getting hypertension compared to alcohol non-consumer and nonsmoker with 95% confidence intervals were 1.08-4.80 and 1.21-6.10, respectively. Persons with family history of hypertension have 3.8 times more chance of getting hypertension compared to no family history of hypertension with 1.89-7.61 of 95% confidence interval.Conclusion: Lifestyle modification reduces blood pressure which prevents or delays the incidence of hypertension. Hypertension can be controlled and prevented by modifying the lifestyle. People should be advised to avoid modifiable risk factors of hypertension like smoking, consumption of alcohol and physical inactivity through health education programs.Nepalese Journal of Statistics, 2017, Vol. 1, 73-82

scholarly journals Isolated night cough in children: how does it differ from wheeze?

2020 ◽  
Vol 6 (4) ◽  
pp. 00217-2020
Author(s):  
Maja Jurca ◽  
Myrofora Goutaki ◽  
Philipp Latzin ◽  
Erol A. Gaillard ◽  
Ben D. Spycher ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Variant Form ◽  
Older Children ◽  
Cough Variant Asthma ◽  
Asymptomatic Children ◽  
Increased Risk ◽  
History Of ◽  
Male Sex ◽  
Similar Risk

It has been postulated that some children with recurrent cough but no wheeze have a mild form of asthma (cough variant asthma), with similar risk factors and an increased risk of future wheeze.This longitudinal study compared risk factors for isolated night cough and for wheeze in the Leicester Respiratory Cohort in children aged 1, 4, 6 and 9 years and compared prognosis of children with isolated night cough, children with wheeze and asymptomatic children.We included 4101 children aged 1 year, 2854 aged 4 years, 2369 aged 6 years and 1688 aged 9 years. The prevalence of isolated night cough was 10% at age 1 year and 18% in older children. Prevalence of wheeze decreased from 35% at 1 year to 13% at 9 years. Although several risk factors were similar for cough and wheeze, day care, reflux and family history of bronchitis were more strongly associated with cough, and male sex and family history of asthma with wheeze. Over one-third of preschool children with cough continued to cough at school age, but their risk of developing wheeze was similar to that of children who were asymptomatic at earlier surveys. Wheeze tracked more strongly throughout childhood than cough.In conclusion, our study showed that only some risk factors for cough and wheeze were shared but many were not, and there was little evidence for an increased risk of future wheeze in children with isolated night cough. This provides little support for the hypothesis that recurrent cough without wheeze may indicate a variant form of asthma.

scholarly journals Contagious Bovine Pleuropneumonia: Sero-prevalence and associated risk factors in Gudeya Bila and Boneya Boshe Districts of East Wollega Zone, Oromia, Ethiopia

2020 ◽  
Vol 24 (1) ◽  
Author(s):  
Tolesa Neggasa ◽  
Feyissa Begna ◽  
Moti Wakgari ◽  
Sisay Shibashi ◽  
Eshetu Gezahegn ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Condition Score ◽  
Previous History ◽  
Individual Animal ◽  
Contagious Bovine Pleuropneumonia ◽  
African Countries ◽  
Herd Level ◽  
Mycoplasma Mycoides ◽  
History Of ◽  
Associated Risk Factors

Contagious bovine pleuropneumonia (CBPP) remains a huge threat to cattle production in sub Saharan African countries in general and in Ethiopia in  particular. A cross sectional study was conducted between November, 2017 and June, 2018 to estimate the seroprevalence and associated risk factors of CBPP in the Gudeya Bila and Boneya Boshe districts of East Wollega Zone, Oromia Regional State. The study was conducted on 384 cattle with no history of vaccination against CBPP, using systematic random sampling technique. Blood samples were collected from the jugular vein of each animal and tested by competitive ELISA. Information on risk factors influencing the occurrence of CBPP was collected using questionnaire survey. Data obtained from both serological and questionnaire surveys were analyzed by using SPSS software version 20. Logistic regression was used to analyze the association of exposure variables with anti-mycoplasma mycoides subspecies small colony antibodies. The results indicated that, the overall seroprevalence of CBPP at individual animal-level and herd-level was 8.6% and 26.3%, respectively. There was a statistically significant association in the sero-prevalence of Mycoplasma mycoides subsp. mycoides SC (MMmsSC) antibody (P< 0.05) with the poor body condition score, origin of animals (purchasing from outside of herd) and previous history of CBPP disease at individual animal and large herd size at herd level. This study showed that the overall prevalence of CBPP in study area was high. This warrants the implementation of appropriate preventive and control practice. Keywords: Boneya Boshe, Bovine, CBPP, c-ELISA, Ethiopia, Gudeya Bila, Sero-prevalence

scholarly journals Prevalence of Psoriasis Vulgaris and Its Associated Risk Factors in Pakistan

2021 ◽  
pp. 390-395
Author(s):  
Syeda Ujala Sohail ◽  
Nasima Iqbal ◽  
Ashok Kumar ◽  
Sarwath Fatimee ◽  
Ayesha Khan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Standard Deviation ◽  
Family History ◽  
Psoriasis Vulgaris ◽  
Age Of Onset ◽  
Strong Association ◽  
Positive Family History ◽  
P Value ◽  
History Of ◽  
Associated Risk Factors

Aim: To find out the prevalence of psoriasis vulgaris and its associated risk factors. Study Design: Descriptive cross-sectional. Place and Duration of Study: Study was conducted at Rawalpindi Leprosy Hospital during January 2019 to December 2019. Methodology: The diagnosed cases of Psoriasis Vulgaris (PsV) were included in the study. All the patients were investigated on the basis of an in depth Performa. The Performa include all the relevant clinical and family history of the patient along with the personal details. Data was analyzed by using Statistical Package for the Social Sciences (SPSS) version 20. All the numerical variables were presented as mean with standard deviation while categorical data as frequency and percentages. The association of risk factors with the Psoriasis was calculated by using the Chi-square test. p-value less than 0.05 was considered as significant. Results: Mean age with standard deviation of patients was 34.7±14. Most of the diagnosed patients were male and below 40 years of age, only 4.2% cases were having positive family history of Psoriasis and found significant correlation. The frequency of onset of symptoms in adolescent was more as compared to childhood i.e. 95.3% and 4.7% respectively. Majority of psoriasis cases (65.3%) were from non-smoker group and having strong association with smoking. The frequency of arthritis among psoriasis patients was 23.7% and majority of the patients, who developed arthritis were those having age <40 year and were suffering from psoriasis since 5-10 years. Conclusion: Current study concluded that Psoriasis vulgar is having higher prevalence rate among male and below 40 years of age group. The results also suggested a strong association of severity of psoriasis with certain risk factors including family history, age of onset of symptoms, smoking and arthritis.

scholarly journals Isolated night cough in children: how does it differ from wheeze?

2019 ◽  
Author(s):  
Maja Jurca ◽  
Myrofora Goutaki ◽  
Philipp Latzin ◽  
Erol A. Gaillard ◽  
Ben D. Spycher ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
School Age ◽  
Older Children ◽  
Mild Form ◽  
Cough Variant Asthma ◽  
Asymptomatic Children ◽  
Increased Risk ◽  
History Of ◽  
Male Sex

AbstractBackgroundChildren with night cough but no wheeze might have a mild form of asthma (cough variant asthma), sharing risk factors with children who wheeze, and possibly developing wheeze later.MethodsWe compared risk factors of children with isolated night cough and children with wheeze in the Leicester Respiratory Cohort study at ages 1, 4, 6, and 9 years. We also compared prognoses of children with isolated night cough, children with wheeze, and asymptomatic children.ResultsAmong 4,101 children at age 1 year, 2,854 at 4, 2,369 at 6, and 1,688 at 9 years, the prevalence of isolated night cough was 10% at age 1 and 18% in older children, while prevalence of wheeze decreased from 35% at 1 year to 13% at age 9. Although many risk factors were the same for cough and wheeze, day care, reflux, and family history of bronchitis were more strongly associated with cough, and male sex and family history of asthma with wheeze. Over one-third of pre-schoolers with cough continued to cough at school age, but their risk of developing wheeze was similar to that of children asymptomatic at earlier surveys. Wheeze tracked more strongly throughout childhood than cough.ConclusionsSome risk factors for cough and wheeze were shared and some were not; there was little evidence that children with isolated night cough have an increased risk of future wheeze. This suggests that only a fraction of children with isolated night cough might have a variant of asthma, if at all.

scholarly journals Risk Factors Associated with Gestational Diabetes among Pregnant Women in Owerri Municipal Council, Southeastern Nigeria

2013 ◽  
Vol 5 (1) ◽  
pp. 39-46 ◽  
Author(s):  
JC Nwaokoro ◽  
CO Emerole ◽  
SNO Ibe ◽  
AN Amadi ◽  
INS Dozie
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Gestational Diabetes ◽  
Pregnant Women ◽  
Significant Relationship ◽  
Previous History ◽  
Southeastern Nigeria ◽  
Family History Of Diabetes ◽  
Factors Associated ◽  
History Of

Background Gestational diabetes is emerging as a serious public health problem in Nigeria where the largest number of people with diabetes in Africa occurs. Current studies in Nigeria give an overall prevalence of gestational diabetes as 13.4% among pregnant women with unidentified risk factors. Aims and Objectives This study aimed at investigating the risk factors associated with gestational diabetes. Materials and Methods A cross-section analytical study design was adopted for this research and comprising a total of 100 pregnant women receiving ante-natal health care service at the Federal Medical Center, Owerri. A structured questionnaire including a set of detailed pre-determined questions was administered on the subjects. Data collected were analyzed statistically, using chi-square and T test. Results The results obtained suggest that there is a significant relationship (p<0.05) between previous macrosomic baby, parity, previous history of caesarean section, family history of diabetes and occurrence of gestational diabetes, respectively. However, there is no significant relationship (p>0.05) between history of miscarriages and stillbirth, socioeconomic status and occurrence of gestational diabetes. A family history of diabetes is independently and significantly associated with the development of gestational diabetes itself even after adjusting for other risk factors. Conclusion This study will be a working tool to guide obstetricians and midwives in counseling and advising women of their risk of developing GDM. DOI: http://dx.doi.org/10.3126/ajms.v5i1.8302 Asian Journal of Medical Science Vol.5(1) 2014 pp.39-46  

scholarly journals Efficacy of prednisolone for children with acute bronchiolitis having family history of atopy: A randomized placebo-controlled trial

2015 ◽  
Vol 6 (1) ◽  
pp. 9-11
Author(s):  
Md Abid Hossain Mollah ◽  
Khondokar Jahirul Hasan ◽  
M Ekhlasur Rahman ◽  
Shegufta Rahman
Keyword(s):  
Placebo Group ◽  
Family History ◽  
Hospital Stay ◽  
Oxygen Therapy ◽  
Controlled Trial ◽  
Length Of Hospital Stay ◽  
Oral Prednisolone ◽  
Acute Bronchiolitis ◽  
Medical College ◽  
History Of

Objective : To determine the efficacy of oral prednisolone among children with acute bronchiolitis who have associated family history of atopy.Materials and Methods : This randomized double blind placebo controlled trial was carried out in Dhaka Medical College Hospital during July’08 to June’10. A total of sixty patients (1-24 months) of acute bronchiolitis who had family history of atopy (e.g. allergic rhinitis, allergic conjunctivitis, asthma, eczema) were enrolled. After enrollment, allocation of either prednisolone or placebo to the study subjects were done randomly by lottery method and the researcher remained blind about the allocation. Finally 30 cases received prednisoloneorally at a dose of 2mg/kg/day 8 hourly for 3 consecutive days and 30 cases received placebo (made of flour). In addition, both the groups got same supportive measures. During intervention, study subjects were monitored by Modified Respiratory Distress Assessment Instrument (MRDAI) score twice daily for consecutive 3 days. Duration of oxygen therapy as well as length of hospital stay was also determined. Data were analyzed using appropriate statistical tests and a p value of <0.05 was considered significant.Results : The respiratory rate, accessory muscle use and auscultatory finding scores were significantly declined in Prednisolone group than the placebo group (p<.05). However, cyanosis score though declined in both groups, the difference was not significant (p>.05). Mean duration of oxygen therapy needed in Prednisolone group was significantly lesser than the placebo group (13.7 vs 24.1 hours; P<.01). Similarly, the length of hospital stay was shorter in prednisolone group than in placebo group (3.3 vs 4.6days; p<.01).Conclusions : Three days of oral prednisolone therapy along with supportive measures was found to be significantly useful among children with acute bronchiolitis having family history of atopy in terms of clinical recovery, oxygen requirement and duration of hospital stayNorthern International Medical College Journal Vol.6(1) 2014: 9-11

scholarly journals Sero-Prevalence and Associated Risk Factors of Bovine Brucellosis in Sendafa, Oromia Special Zone Surrounding Addis Ababa, Ethiopia

2020 ◽  
Author(s):  
Hadji Bifo ◽  
Getachew Gugsa ◽  
Tsegabirhan Kifleyohannes ◽  
Engidaw Abebe ◽  
Meselu Ahmed
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Previous History ◽  
Animal Origin ◽  
Bacterial Disease ◽  
Potential Hazard ◽  
Bovine Brucellosis ◽  
History Of ◽  
Associated Risk Factors ◽  
Special Zone

AbstractBovine brucellosis is an infectious bacterial disease caused by members of genus Brucella, affecting both animals and humans, and resulting in a serious economic loss in animal production sector and deterioration of public health. This cross-sectional study was conducted from November 2014 to April 2015 to determine the sero-prevalence and associated risk factors of bovine brucellosis in Sendafa, Oromia special Zone, Ethiopia. A total of 503 blood samples were collected using simple random sampling technique from dairy cattle of above 6 months of age with no history of previous vaccination against brucellosis. All sera samples were demonstrated using both Rose Bengal Plate Test for screening and Compliment Fixation Test for confirmation. Accordingly, the overall sero-prevalence of bovine brucellosis in this area was 0.40%. The result showed that the sero-prevalence of bovine brucellosis in the study area was not statistically significant with all proposed risk factors. Thus, the study revealed the absence of significant statistical variation in the sero-prevalence of bovine brucellosis in different age, sex groups, breeding method and history of previous abortions (P>0.05). No reactors were observed in male animals. Sero-prevalence of 0.40% was observed in animals without previous history of abortion. Moreover, information was gathered on individual animal and farm-level risk factors and other farm characteristics using a questionnaire. The awareness among the society was poor, so the positive animals can be a potential hazard to animals and humans in the study area. Therefore, public education should be done in order to improve the awareness of people on bovine brucellosis and its public health impact with due consideration on the safely consumption of food of animal origin.

scholarly journals Risk factors of asthma in the Asian population: a systematic review and meta-analysis

2021 ◽  
Vol 40 (1) ◽  
Author(s):  
Yang Yie Sio ◽  
Fook Tim Chew
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Family History ◽  
Meta Analysis ◽  
Random Effect ◽  
Asian Population ◽  
Related Risk ◽  
The Family ◽  
History Of ◽  
Associated Risk Factors

Abstract Background and objective An increasing trend of asthma prevalence was observed in Asia; however, contributions of environmental and host-related risk factors to the development of this disease remain uncertain. This study aimed to perform a systematic review and meta-analysis for asthma-associated risk factors reported in Asia. Methods We systematically searched three public databases (Web of Science, PubMed, and Scopus) in Feb 2021. We only included articles that reported environmental and host-related risk factors associated with asthma in the Asian population. Random-effect meta-analyses were conducted for frequently reported asthma-associated risk factors to provide an overall risk estimate of asthma development. Results Of 4030 records obtained from public databases, 289 articles were selected for review. The most frequently reported asthma-associated risk factor was the family history of allergy-related conditions. The random-effect asthma risk estimates (pooled odds ratio, OR) were 4.66 (95% confidence interval (CI): 3.73–5.82) for the family history of asthma, 3.50 (95% CI: 2.62–4.67) for the family history of atopy, 3.57 (95% CI: 3.03–4.22) for the family history of any allergic diseases, 1.96 (95% CI: 1.47–2.61) for the family history of allergic rhinitis, and 2.75 (95% CI: 1.12–6.76) for the family history of atopic dermatitis. For housing-related factors, including the presence of mold, mold spots, mold odor, cockroach, water damage, and incense burning, the random-effect pooled OR ranged from 1.43 to 1.73. Other risk factors with significant pooled OR for asthma development included male gender (1.30, 95% CI: 1.23–1.38), cigarette smoke exposure (1.44, 95% CI: 1.30–1.60), cigarette smoking (1.66, 95% CI: 1.44–1.90), body mass index (BMI)–related parameters (pooled OR ranged from 1.06 to 2.02), various types of air pollution (NO2, PM10, and O3; pooled OR ranged from 1.03 to 1.22), and pre- and perinatal factors (low birth weight, preterm birth, and cesarean section; pooled OR ranged from 1.14 to 1.32). Conclusions The family history of asthma was the most frequently reported risk factor for asthma development in Asia with the highest risk estimate for asthma development. This suggests a major role of the genetic component in asthma pathogenesis. Further study on asthma genetics is required to improve the current understanding of asthma etiology.

scholarly journals Risk factors for early wheezing in preterm infants: a retrospective cohort study

2020 ◽  
Author(s):  
Xun Chen ◽  
Minjing Yang ◽  
Shengzhu Huang ◽  
Xiaolian Qin ◽  
Zhijian Pan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Family History ◽  
Preterm Infants ◽  
Full Term ◽  
Term Infants ◽  
History Of ◽  
Group A ◽  
Male Sex ◽  
Group B

Abstract Background: The factors that cause recurrent wheezing in children are complex, and premature delivery may be one of these factors. Little is known about early wheezing in preterm infants.Methods: Data were sourced from 1616 children born between 2007 and 2013 from 8 hospitals in Guangxi, China. All children were followed up by telephone or questionnaire through the sixth year of life. Children were grouped by gestational age (GA): Group A, GA ≤ 32 weeks; Group B, 32 weeks < GA < 37 weeks; and Group C, 37 weeks ≤ GA < 42 weeks.Results: The incidences and risk factors for early wheezing in preterm infants were analysed. The incidences of early wheezing were as follows: Group A > Group B > Group C. The incidence of persistent early wheezing in Group A or Group B was significantly higher than that in Group C, respectively. SGA (95% CI: 1.097 to 7.519) was a risk factor for early wheezing in group A. Male sex (95% CI: 1.595 to 4.501) and family history of allergies (95% CI: 1.207 to 3.352) were risk factors for early wheezing in group B.Conclusions: 1. New-borns with younger GAs had a higher risk of early wheezing. 2. The incidence of persistent early wheezing for preterm infants (GA ≤ 32 weeks and 32 weeks < GA < 37 weeks) was higher than that for full-term infants (37 weeks ≤ GA < 42 weeks). 3. SGA was a risk factor for early wheezing in preterm infants with a GA ≤ 32 weeks. 4. Male sex, personal history of allergies and family history of allergies were all possible factors affecting early wheezing in preterm infants with a GA > 32 weeks but < 37 weeks and full-term infants. Among them, male sex and family history of allergies were risk factors for early wheezing. 5. Mode of delivery, passive smoking, breastfeeding and invasive mechanical ventilation were not possible risk factors for early wheezing in infants of different GAs.

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