scholarly journals An overview of Mycotoxin contamination of animal feeds

Author(s):  
MZ Hassan ◽  
MM Rahman ◽  
MZ Ali ◽  
MA Yousuf ◽  
S Akther ◽  
...  

Mycotoxins contamination of animal feeds remains a great concern for animal feed safety, public health and economic significance. It may occur in various foods and feeds stuffs from agricultural commodities to finished foods and feeds of animal. Hot, humid weather and late harvesting of grains favored the mold and fungal growth in cereal crops. There are around 400 types of mycotoxins in which aflatoxin, deoxyinalenol (vomitoxin), fumonisin, zearalenone and ochratoxins are important for animal and human foods. However, presence of mold or fungi in the grains does not mean that mycotoxins are present in feeds or foods. The acceptable level of aflatoxins, deoxyinalenol (vomitoxin), fumonisin, zearalenone and ochratoxins are in livestock feeds are 20 ppb, 10 ppm, 5 ppm and 3-10 ppm and 3-20 (μg/kg) respectively. Mycotoxins can be found in contaminated cereal grains, straw and silage. The most detrimental effects of mycotoxins are hepatic, digestive, immunological, reproductive disorders, teratogenicity, nephrotoxicity, edema and carcinogenicity etc. of animal and human being. Adsorbents and activated charcoal in animal feeds bind the toxic substances. There are some regulations but not in all countries aimed to prevent and control mycotoxins in industrial processed foods and animal feeds but not in locally processed ones. A number of strategies in some countries for preventing mycotoxins have been mobilized but the awareness for implementation is very weak. Mass media can play an important role to build awareness to mycotoxin. Bangladesh J. of Livestock Res. 21-25: 1-9, 2018

Author(s):  
Regiane R. Santos ◽  

Feed safety remains an issue for both the health of livestock and as a prerequisite for food safety. Risk assessment plays a role in identifying and determining potential risks of contaminants. When contaminants limits are defined, risk management systems can be designed for prevention and control. Finally, risk communication covers the technical information shared between governments, academia, the different players involved in feed production, and the public. This chapter focuses on management systems used to prevent and control contaminants in animal feed. A brief introduction to feed contaminants and new feed ingredients is given, followed by a description of the main risk management systems applied in Europe and the US.


1976 ◽  
Vol 59 (1) ◽  
pp. 56-59 ◽  
Author(s):  
Ugo R Cieri

Abstract The animal feed sample is extracted with ethanol or acetone and the extract is evaporated to dryness. Another portion of the same sample, spiked at the 3 ppm level with 8 sulfonamides, is similarly extracted and the extract is evaporated to dryness. The residue from each solution is dispersed with 5 ml 0.1N NaOH and, following the addition of 1 ml 1N HCl and mixing, the solution is filtered. The filtrate is mixed with Celite, transferred to a column, and eluted with ammoniacal ether. Aliquots of the concentrated sample and control eluates are spotted on a neutral Adsorbosil-1 thin layer chromatographic (TLC) plate. Following development in chloroform-methanol (95+5) and drying, the plate is sprayed with an alcoholic solution of p-dimethylaminobenzaldehyde until the control chromatogram shows 6 yellow spots which are, from top to bottom; sulfadimethoxine (SO), the combined sulfamerazine (SM)-sulfamethazine (SH)-sulfaquinoxoline (SQ) spot, sulfadiazine (SD), sulfapyridine (SP), sulfathiazole (SZ), and sulfaguanidine (SG). A spot on the sample chromatogram can be identified if the Rf is identical to one of the 5 sulfonamides not overlapping with another compound. If the Rf of the sample spot is approximately the same as that of the combined SM-SH-SQ spot, more definite identification can be obtained by using basic Adsorbosil-1 TLC plates, with chloroform-methanol (92+8) as the developing solvent.


2015 ◽  
Vol 8 (5) ◽  
pp. 603-617 ◽  
Author(s):  
V. Dell’Orto ◽  
G. Baldi ◽  
F. Cheli

Silage has a substantial role in ruminant nutrition. Silages as a source of mycotoxigenic fungi and mycotoxins merit attention. Fungal growth and mycotoxin production before and during storage are a well-known phenomenon, resulting in reduced nutritional value and a possible risk factor for animal health. Mycotoxin co-contamination seems to be unavoidable under current agricultural and silage-making practices. Multi-mycotoxin contamination in silages is of particular concern due to the potential additive or synergistic effects on animals. In regard to managing the challenge of mycotoxins in silages, there are many factors with pre- and post-harvest origins to take into account. Pre-harvest events are predominantly dictated by environmental factors, whereas post-harvest events can be largely controlled by the farmer. An effective mycotoxin management and control programme should be integrated and personalised to each farm at an integrative level throughout the silage production chain. Growing crops in the field, silage making practices, and the feed out phase must be considered. Economical and straightforward silage testing is critical to reach a quick and sufficiently accurate diagnosis of silage quality, which allows for ‘in field decision-making’ with regard to the rapid diagnosis of the quality of given forage for its safe use as animal feed. Regular sampling and testing of silage allow picking up any variations in mycotoxin contamination. The use of rapid methods in the field represents future challenges. Moreover, a proper nutritional intervention needs to be considered to manage mycotoxin-contaminated silages. At farm level, animals are more often exposed to moderate amounts of several mycotoxins rather than to high levels of a single mycotoxin, resulting more frequently in non-specific digestive and health status impairment. Effective dietary strategies to promote rumen health, coupled with the administration of effective and broad-spectrum mycotoxin detoxifiers, are essential to minimise the negative impact of mycotoxins.


2020 ◽  
pp. 66-72
Author(s):  
Irina A. Piterskikh ◽  
Svetlana V. Vikhrova ◽  
Nina G. Kovaleva ◽  
Tatyana O. Barynskaya

Certified reference materials (CRM) composed of propyl (11383-2019) and isopropyl (11384-2019) alcohols solutions were created for validation of measurement procedures and control of measurement errors of measurement results of mass concentrations of toxic substances (alcohol) in biological objects (urine, blood) and water. Two ways of establishing the value of the certified characteristic – mass consentration of propanol-1 or propanol-2 have been studied. The results obtained by the preparation procedure and comparison with the standard are the same within the margin of error.


1992 ◽  
Vol 25 (3) ◽  
pp. 13-21
Author(s):  
R. L. Williamson

The American approach to environmental regulation is characterized by fragmentation of responsibilities, primary reliance on command and control regulations, extraordinary complexity, a preference for identifiable standards, and heavy resort to litigation. This system has provided important benefits, including significant reduction of environmental contamination, substantial use of science in decision-making, broad participatory rights, and the stimulation of new treatment technologies. However, these gains have been achieved at excessive cost. Too much reliance is placed on command and control methods and especially on technology-based standards. There is too much resort to litigation, and inadequate input from science. Participatory rights are being undermined, and there is a poor allocation of decision-making among the federal agencies and the states. Over-regulation sometimes leads to under-regulation, and insufficient attention is given to the impact on small entities. The responsibility for these difficulties rests with everyone, including the federal agencies, the Congress, the general public and the courts. Changes in the regulatory system are needed. We should abandon the use of technology-based standards to control toxic substances under the Clean Water Act in favor of strong health- and environmentally based standards, coupled with taxes on toxic substances in wastewater.


1979 ◽  
Vol 59 (2) ◽  
pp. 333-337
Author(s):  
T. F. SHARBY

Antibiotics have been used in animal feeds for almost 30 yr to improve growth, enhance feed efficiency, and control disease in birds and animals. In 1974 antibiotics used in animal feeds in Canada totalled 13.31 million dollars while those used in veterinary medicine totalled 28.8 million dollars. Antibiotics, sulfonamides and antibacterials used in human application that same year equalled 77.4 million dollars. Concerns regarding potential health hazards to humans with continued low-level antibiotic supplementation of animal feeds have resulted in a number of countries implementing or proposing more rigid legislation covering antibiotic use in animal agriculture. Possible consequences of such legislation being introduced in Canada are discussed.


2005 ◽  
Vol 34 (4) ◽  
pp. 243-248
Author(s):  
L. Pinotti ◽  
V.M. Moretti ◽  
A. Baldi ◽  
F. Bellagamba ◽  
A. Campagnoli ◽  
...  

The protracted outbreak of mad-cow disease, repeated episodes of dioxin and mycotoxin contamination, and the issue of labelling genetically modified foods have severely shaken public confidence in the food supply industry, increasing consumer concerns about the origins of the raw materials used in both animal feed and food products. The need to develop improved techniques to characterize feed and food components has consequently become more urgent, and DNA-based technologies promise to be able to meet these needs. DNA methods can establish the origin of species in meat- and fish-based products and feed ingredients, and are the most reliable analytical approaches for authenticating processed foodstuffs. The identification of ingredients in processed feed and food is mandatory not only to ensure correct labelling and assessment of value, but also to avoid health risks related to the presence of toxic contaminants or pathogenic agents.


Toxins ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 92
Author(s):  
Dipendra Kumar Mahato ◽  
Sheetal Devi ◽  
Shikha Pandhi ◽  
Bharti Sharma ◽  
Kamlesh Kumar Maurya ◽  
...  

Mycotoxins represent an assorted range of secondary fungal metabolites that extensively occur in numerous food and feed ingredients at any stage during pre- and post-harvest conditions. Zearalenone (ZEN), a mycotoxin categorized as a xenoestrogen poses structural similarity with natural estrogens that enables its binding to the estrogen receptors leading to hormonal misbalance and numerous reproductive diseases. ZEN is mainly found in crops belonging to temperate regions, primarily in maize and other cereal crops that form an important part of various food and feed. Because of the significant adverse effects of ZEN on both human and animal, there is an alarming need for effective detection, mitigation, and management strategies to assure food and feed safety and security. The present review tends to provide an updated overview of the different sources, occurrence and biosynthetic mechanisms of ZEN in various food and feed. It also provides insight to its harmful effects on human health and agriculture along with its effective detection, management, and control strategies.


2014 ◽  
Vol 43 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Cíntia Lima Gouveia ◽  
Isabelle Cristine Melo Freire ◽  
Maria Luísa de Alencar e Silva Leite ◽  
Rebeca Dantas Alves Figueiredo ◽  
Leopoldina de Fátima Dantas de Almeida ◽  
...  

Introduction: The effectiveness of antimicrobial solutions employed in dental prosthesis decontamination is still uncertain. Aim: To evaluate the antifungal activity of cleaners used in the decontamination of dental prostheses on the growth of Candida albicans. Material and method: The evaluated products were: Corega Tabs(r) (S1), Sodium Hypochlorite 1% (S2), Sodium Bicarbonate 1% (S3), Hydrogen Peroxide 1% (S4), Chlorhexidine Digluconate 0.12% - Periogard (r) (S5), Mouthrinse based on essential oils - Listerine(r) (S6), essential oil from Rosmarinus officinalis (rosemary) at concentrations of 1% (S7) and 2% (S8). The antifungal activity of the products was evaluated by agar diffusion technique and the determination of microbial death curve of samples of C. albicans (ATCC 90028) in concentration 1.5 × 106 CFU/mL. The tests were performed in triplicate and statistical analysis was made by ANOVA Two-Way and Tukey tests, with the confidence level of 95%. Result: The average of the zones of inhibition growth, in millimeters, obtained for the products were: 0.0 (S1), 44.7 (S2), 0.0 (S3), 21.6 (S4), 10.0 (S5), 6.1 (S6), 0.0 (S7) and 2.4 (S8). Considering the determination of microbial death curve, all products showed a statistical difference (p<0.01) from control (0.85% sodium chloride) and S3 groups. Fungal growth less than 2×104 CFU/mL and an accentuation of the microbial death curve were observed after 30 minutes, with exception for S3 and control groups. Conclusion: The studied compounds, with the exception of Sodium Bicarbonate, have antifungal effect against C. albicans, which contribute for dental prostheses hygiene.


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