scholarly journals Nutritional Status and Short Term Outcome of Hospitalized Patients with Stroke

2015 ◽  
Vol 14 (2) ◽  
pp. 61-64
Author(s):  
Md Moazzem Hossain Chowdhury ◽  
Sheikh Khairul Kabir ◽  
Muhammed Syedul Alam ◽  
AKM Humayon Kabir ◽  
Sujat Paul ◽  
...  

Nutrition and stroke is an interrelated problem now-a-days. They influence the pattern and outcome of the stroke. The purpose of this study is to see the different nutritional parameters with their interrelation with stroke and in-hospital outcome of admitted stroke patients. It is a hospital based descriptive cross sectional study conducted on purposively selected (non-probability) hospitalized patients who had been admitted into the neurology wards, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during a period of 6 months. Cases (n = 50) with CT scan of brain done were interviewed and examined and had measurements of height, weight, waist and hip circumference, waist-to-Hip Ratio (WHR) and Mid-Upper Arm Circumference (MUAC) calculated along with serum albumin level. Out of 50 patients of this study 36 (72%) were males and 14 (28%) were females; Male to female ratio was 2.6:1. It was found that 26 (52%) patients were 60 years and above, 1 (2%) in the age group of 20-30 years, 3 (6%) in the age group of 30-39 years, 4 (8%) in the age group of 40-49 years and 16 (32%) were in the age group of 50-59 years The mean hip circumference of the study people was 95 cm. WHR was calculated for each patient, the result of which shows that 33 (66%) patients had abnormal WHR while 17 (34%) patients had been found to possess normal WHR. Body Mass Index (BMI) was calculated for each patient, the result of which shows that 24 (48%) patients had abnormal BMI while 26 (52%) patients had been found to possess normal BMI. MUAC was calculated for each patient, the result of which shows that 22 (44%) patients had abnormal MUAC while 28 (56%) patients had been found to possess normal MUAC. Serum albumin level was measured for each patient, the result of which shows that 17 (34%) patients had low serum albumin (<3gm/l) while 33 (66%) patients had been found to possess normal serum albumin (>3gm/l). Regarding analysis of BMI and WHR with different types of stroke WHR was found significantly different regarding normal and abnormal records (p<0.05). Regarding BMI it was not significant (p>0.05). Among 50 patients with stroke 32 (64%) patients got either partial (44%) or clinical recovery (20%) from the disease, 12 (24%) patients showed no noticeable improvement and 6 (12%) patients expired. The results revealed that nutrition has some influence and association with stroke and in-hospital outcome of the stroke patient varies.Chatt Maa Shi Hosp Med Coll J; Vol.14 (2); Jul 2015; Page 61-64

2021 ◽  
Vol 8 (04) ◽  
pp. 204-207
Author(s):  
Shreyansh Talera ◽  
Saurabh Singhal ◽  
Nishant Wadhera ◽  
Mayank Arora ◽  
Ravi Pratap

BACKGROUND WHO has declared Coronavirus disease 2019 (Covid-19) as a pandemic. Covid-19 leads to sickness and death. Human serum albumin (HSA) is the most common circulating protein in the body having oncotic as well as non-oncotic properties. The role of albumin in death among Covid-19 subjects, especially in this part of the country has not been frequently reported. The aim of the study was to analyse the role of serum albumin level as prognostic marker for Covid-19 positive patients. METHODS The present study was conducted in the department of Medicine at Chhatrapati Shivaji Subharti Hospital, Subharti Medical College, Meerut, UP. The study comprised of 100 subjects who were Covid positive from May 2020 to July 2020. A detailed explanation was given to all the participating respondents regarding the study and their contribution to it. Covid-19 was diagnosed on the basis of the WHO interim guidelines. A questionnaire was prepared to collect the patients’ demographic profile. Patients date of admission and discharge was recorded along with the outcome i.e., whether patient expired or survived. Patients’ diagnosis was identified along with the comorbidity (if present). Laboratory investigations comprised of CBC and serum albumin detection. Data so collected was tabulated in an excel sheet, under the guidance of statistician. Collected data was analysed using Statistical Package for the Social Sciences (SPSS) software version 24 and the tests used were t test and Fisher’s exact test and the level of significance was set at p < 0.05. RESULTS The study comprised of 100 subjects, out of which 45 were males and 55 were females. The overall mean age of the study subjects was 37.52 years. In our study, mortality was 35.29 %, 9.33 % and 85.7 % of the subjects having Covid-19+ type 2 diabetes (T2DM), only Covid-19 and Covid-19+ hypertension respectively with statistically significant difference as p < 0.05. Albumin level was significantly lower in expired patients (2.99) as compared to survivors (3.85) as p < 0.05. Hospital stay was also higher in expired patients. CONCLUSIONS Covid-19 patients had low serum albumin levels and that might play a role in the survival of patient. KEYWORDS Covid-19, Mortality, Albumin


2019 ◽  
Vol 26 (03) ◽  
Author(s):  
Nadia Ijaz ◽  
Tazeen Nazar ◽  
Bilal Aziz

Objectives: To determine the correlation between serum albumin levels and the grades of esophageal varices in patients of liver cirrhosis due to hepatitis B and C. Study Design: Cross-sectional descriptive study. Place and Duration of Study: Unit I, Department of Medicine, Allied Hospital, Faisalabad from 29th June, 2014 to 28th December, 2014. Methodology: 95 patients of either sex between 20-70 years of age, with the diagnosis of liver cirrhosis due to hepatitis B and C were selected using non - probability consecutive sampling. The presence of esophageal varices was confirmed by endoscopy. Results: Out of a total of 95 patients, 59 (62.11%) were between the age group of 20-50 years while 36 (37.89%) were between 51-70 years of age. Mean+SD was calculated as 48.37+11.75 years. Gender distribution showed that 51 (53.68%) patients were males and 44 (46.32%) were females. Correlation between serum albumin level and the grade of esophageal varices in patients of liver cirrhosis due to hepatitis B & C showed that out of 26 cases with serum albumin level <2.8, 10 had Grade I and 16 had Grade II while out of 69 cases with ≥2.8 serum albumin level, 40 had grade I and 29 had grade II EV. r value was recorded to be -0.697 whereas p-value was calculated as 0.000. Conclusion: There is a significant negative correlation between serum albumin level and grade of esophageal varices in patients of liver cirrhosis due to hepatitis B and C.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Ngoc Nguyen Thi ◽  
Dien Tran Minh ◽  
Huong Nguyen Thu ◽  
Phuong Luong Thi ◽  
Nam Thai Thien ◽  
...  

Background: The current study intended to determine whether serum albumin level and urine protein/creatinine rate (uPCR) are appropriate predictors of severe lupus nephritis in childhood-onset SLE. Objectives: Following a cross-sectional single-center design, 85 LN children referred to the National Children Hospital, Ha Noi, Viet Nam, from 6/2019 to 6/2020 were recruited. Renal biopsy was performed for all participants. Methods: Following a cross-sectional single-center design, 85 LN children referred to the National Children Hospital, Ha Noi, Viet Nam, from 6/2019 to 6/2020 were recruited. Renal biopsy was performed for all participants. Results: The mean SLEDAI score of all patients was 14.69. The proportion of patients with high and very high SLEDAI was 61.2 and 17.6%, respectively. The mean concentration of serum albumin was 28.55 g/L, and the proportion of decreased albumin concentration was 55.3%. The median uPCR was 446.6 mg/mmol in which 76.5% of values were ≥ 200 mg/mmol. Pathological morphology of LN class from I to VI was observed in 0%, 17.6%, 37.6 %, 37.6%, 7.1%, and 0%, respectively. Serum albumin level and uPCR presented the predictive value for severe and active LN (class IV and V); (AUC: 0.725 P < 0.001 for both). Conclusions: Serum albumin and uPCR were appropriate predictors for severe and active LN in Vietnamese children.


Author(s):  
Fasni Halil ◽  
Hj. Darmawaty ER ◽  
Ruland DN Pakasi

To differentiate the ischemic and hemorrhagic stroke with the most accurate method can be carried out by Computerized Tomography(CT) scan. However, because the restrictor on access and cost, not all patients could gain the advantage of CT scan. Examination ofalbumin is a quick and easy test. The aim of this study was to evaluate the serum albumin level in patient suffering ischemic andhemorrhagic stroke. A cross sectional study of 60 ischemic and hemorrhagic stroke patients was performed at the Neurologic Departmentof Dr. Wahidin Sudirohusodo Hospital Makassar, from March up to August 2008. Albumin – levels was measured using the colorimetricBCG method, using the Cobas Integra 400 Autoanalyser. The data were than analyzed with SPSS 11.5 software and t test. Among the60 samples of the ischemic and hemorrhagic stroke were found mean values of serum albumin level is 3.38 ± 0.120 and hemorrhagicstroke is 3.51 ± 0.0938 with p value is 0.495. There were no significantly different between the serum albumin level of the ischemicand hemorrhagic stroke patients.


Author(s):  
AT. Lopa ◽  
B. Rusli ◽  
M. Arif ◽  
Hardjoeno Hardjoeno

Hepatitis is a inflammation process which may present in an acute or chronic phase. A decrease of serum albumin level may befound in liver disease. Ratio de Ritis in mild hepatitis is < 1 while in alcoholic hepatitis is >1. To analyze serum albumin level withratio de Ritis in hepatitis B patients. A cross sectional study was carried out comprising 46 subjects from October 2005 to August 2006measuring albumin level SGOT and SGPT levels using Lyasis autoanalyzer. Thirty eight males and eight females, the level of serumalbumin decreased with an average of albumin level 2.98 gr/dL (p<0.05). Twenty two subjects showed a ratio de Ritis ≤ 1 with theaverage albumin level 3.00 gr/dL and 24 subjects were included in group ratio de Ritis > 1 with average albumin level 2.96 gr/dL(p value = 0.658). There was a decrease of serum albumin level in hepatitis B patient but no significant difference between decrease ofserum albumin level with ratio of de Ritis ≤ 1 and ratio of de Ritis >1.


2018 ◽  
Vol 9 (1) ◽  
pp. 27-30
Author(s):  
K Kirtania ◽  
A Khatun ◽  
RA Chowdhury ◽  
M Rukunuzzaman

Albumin is a non-glycosylated plasma protein synthesized primarily in the liver. It is a protein involved in the transport of small molecules in the blood and plays a key role in restricting fluid leakage from the vasculature into the tissue. Elevated level of serum albumin is related to haemoconcentration and reduced level is associated with malnutrition and chronic inflammatory diseases representing a negative acute phase protein. This cross sectional study was done to determine the association between admission serum albumin levels and short-term outcome following acute stroke. Consecutive first-ever acute stroke patients were enrolled between January 2016 and December 2016 at DMCH. On admission serum albumin were measured. Patients were then followed up for 10 days and outcome measure at the end of the study were 10- day mortality. Relationship between serum albumin and stroke outcome was determined. A total of 100 stroke cases were thus included in the study comprising 66 males and 34 females. The mean age of patients was 69.2±12.2 years. Of total, 74% patients were of ischemic stroke and 26% were of hemorrhagic stroke. Among them 22 patients expired in the hospitalization period within 10 days and remaining 78 patients were discharged. The mean serum level of albumin was 2.90±0.57 g/dl in the expired group and 3.79±0.51 g/dl in the discharged group. It may be concluded that low admission serum albumin may be significantly associated with poor outcome.Bangladesh J Med Biochem 2016; 9(1): 27-30


PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0199153 ◽  
Author(s):  
Charat Thongprayoon ◽  
Wisit Cheungpasitporn ◽  
Michael A. Mao ◽  
Ankit Sakhuja ◽  
Kianoush Kashani

2019 ◽  
Vol 59 (1) ◽  
pp. 7-12
Author(s):  
Andar Laura Nainggolan ◽  
Sri Sudarwati ◽  
Dany Hilmanto

Background Nephrotic syndrome (NS) is the most common renal disease among children, and contributes to life-threatening complications such as thromboembolic disease. Platelets are considered to be important agents in thrombotic events among NS patients. The gold standard assessment for platelet aggregation is the use of adenosine diphosphate (ADP) agonist, however, it is expensive and not accessible in smaller health facilities. Thus, other thrombosis parameters are needed. Previous studies suggested that low albumin increased the risk of thrombosis in NS patients. Objective To assess for a possible correlation between albumin level and platelet count as well as platelet aggregation. Methods This cross-sectional study was conducted in children with nephrotic syndrome who were admitted to the Pediatric Nephrology Department in Dr. Hasan Sadikin General Hospital, Bandung, West Java, from November 2017 to March 2018. Subjects were selected by consecutive sampling. Serum albumin, platelet count, and platelet aggregation were measured. Statistical analysis was conducted by Spearman’s test. Results A total of 32 patients participated in the study, with mean age of 109 (SD 7.4) months. Most subjects were male (56%). Subjects’ mean serum albumin level was 2.06 (SD 1.23) g/dL; mean platelet count was 453,062.5 (SD 187,443.90)/mm3; and mean platelet aggregation values for ADP agonist concentrations of 10, 5, 2.5, and 1 mM were 86.8 (SD 8.63)%, 82.4 (SD 15.33)%, 66.6 (SD 24.90)%, 34.95 (SD 31.69)%, respectively. Partial correlation analysis revealed significant negative associations between albumin and platelet count as well as platelet aggregation assessed with 1 mM of ADP concentration (P<0.001), with Spearman correlation coefficients of -0.641 and -0.634, respectively. Conclusion Serum albumin level had a moderately negative correlation with platelet count and platelet aggregation value.


2019 ◽  
Vol 74 (6) ◽  
pp. 465-471 ◽  
Author(s):  
Arnaud Ancion ◽  
Sophie Allepaerts ◽  
Sébastien Robinet ◽  
Cecile Oury ◽  
Luc A. Pierard ◽  
...  

2020 ◽  
Vol 60 (2) ◽  
pp. 90-4
Author(s):  
Erni Nuraeni ◽  
Faiisal Faisal ◽  
Ahmedz Widiasta ◽  
Novina Novina

Background Nephrotic syndrome causes loss of medium-sized plasma proteins and binding proteins, resulting in thyroid hormone deficiency. Objective To assess for potential correlations between subclinical hypothyroidism in pediatric nephrotic syndrome with albumin, globulin, and proteinuria. Methods This cross-sectional study was conducted in the Department of Pediatrics, Hasan Sadikin General Hospital, Bandung, West Java. All types of nephrotic syndrome patients aged 1 month to < 18 years were included. Blood and urine specimens were collected from the patients for albumin, globulin, thyroid function (T3, fT4 and TSH), and proteinuria tests and analyzed with standard techniques. Results There were 26 subjects, 20 males and 6 females. Ten subjects developed subclinical hypothyroidism, with mean albumin and thyroid-stimulating hormone (TSH) levels of 0.92 g/dL and 6.9 mIU/L, respectively. There was a negative correlation between albumin level and subclinical hypothyroidism (rpb=-0.702; P<0.001) and a positive correlation between proteinuria and subclinical hypothyroidism (r=0.573; P=0.003). Univariate logistic regression analysis revealed that globulin had no impact on the presence of subclinical hypothyroidism, but albumin and proteinuria did have such an impact. The odds ratios of albumin and proteinuria with subclinical hypothyroidism were 27.00 (95%CI 1.69 to 17.7) and 19.80 (95%CI 1.94 to 201.63), respectively. Conclusion Subclinical hypothyroidism correlates with serum albumin level and proteinuria in nephrotic syndrome patients. Tha low serum albumin level has a high likelihood of subclinical hypothyroidism.  


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