scholarly journals Use of low-cost chemotherapeutic and medicinal plants against Thai silver barb (Barbonymus gonionotus)

2013 ◽  
Vol 10 (2) ◽  
pp. 385-390 ◽  
Author(s):  
MBR Chowdhury ◽  
T Rahman
Keyword(s):  
Medicinal Plants ◽  
Field Condition ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Low Cost ◽  
Fungal Disease ◽  
Bacterial Disease ◽  
Therapeutic Effects ◽  
Black Cumin ◽  
Highly Efficient

Studies were conducted to select and apply the effective low-cost chemotherapeutic and medicinal plants against diseased fish under laboratory and field condition. Thai silver barbs (Barbonymus gonionotus) weighing 20-25 gm were experimentally infected with a virulent bacterial pathogen (Aeromonas hydrophila) and a fungal pathogen (Aphanomyces invadans). Based on the previous studies, four chemotherapeutics, viz., salt + lime, alum, doxycycline and oxytetracycline were selected and applied to observe the therapeutic effects under laboratory and field condition. In the case of medicinal plants, leaves/ bulb / seeds/ rhizome of neem (Azadirachta indica), akand (Calotropis gigantea), garlic (Allium sativum), turmeric (Curcuma longa), shoti (Curcuma zedoaria), Indian sorrel (Oxalis corniculata), guava (Psidum guajava) and kalijira (Nigella sativa) were screened out and applied to the infected fish in laboratory and field condition to determine their efficacies. The antibiotics, both oxytetracycline and doxycycline were found to be very efficient followed by salt + lime and alum. For fungal infection, alum was excellent followed by salt + lime both under laboratory and field condition. Even in the pond trial, alum and salt + lime successfully checked the occurrence of epizootic ulcerative syndrome (EUS) and similar diseases. In the case of medicinal plants, neem and akand together reduced the occurrence bacterial and fungal disease. Garlic was very efficient to check bacterial infection but weak against fungal disease. Turmeric and arrowroot were found to be highly effective against fungal disease but moderately effective against bacterial disease. Field trial revealed that Indian sorrel and guava were highly efficient against bacterial disease but poorly efficient against fungal disease. On the other hand, arrowroot and black cumin were highly efficient against fungal disease but moderately efficient against bacterial disease. The results would be useful to the all concerned for proper health management of cultured fishes.DOI: http://dx.doi.org/10.3329/jbau.v10i2.14932 J. Bangladesh Agril. Univ. 10(2): 385-390, 2012

Antiviral and Immunity-modulating Natural Herbs in the Prevention of COVID-19

2021 ◽  
pp. 81-94
Author(s):  
Sonali S Gadge
Keyword(s):  
Immune System ◽  
Medicinal Plants ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Antiviral Drug ◽  
Herbal Medicines ◽  
Echinacea Purpurea ◽  
Black Pepper ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum

The COVID-19 has spread all over the world and there is no single drug or medicine for the prevention and the treatment of this deadly disease. One can get prevention from this disease by boosting the immune system. Persons with weak immune system e.g. children, elder patients or patients with preexisting diseases affect rapidly due to coronavirus. This novel coronavirus attacks mainly on the person immunity. For the centuries the herbal medicinal plants have many beneficial effects against deadly viruses. Herbal medicines provide a rich resource for new antiviral drug development. These natural agents interact with the life cycle of virus such as virus entry, replication, assembly and release. In this review, the importance, immunomodulator, antiviral and pharmacological activities of some medicinal plants, namely, Allium Sativum, Zingiber Officinalis, Cinnamomum zeylanicum, Curcuma longa, Ocimum sanctum, Glycyrrhiza glabra, Ginseng, Black pepper, Emblica officinalis, Withania somnifera, Tinospora cordifolia, Echinacea purpurea, Azadirachta indica, Piper betel, Eugenia caryophyllata, Cinchona calisaya, Nigella sativa, Cuminum cyminum are highlighted. These medicinal plants have many phytoconstituents like alkaloids, glycosides, terpenoids, flavonoids, lactones, polysaccharides, volatile oils, tannins, resins, etc which are helpful for boosting immunity and will help in the prevention and in the management of COVID-19. Several types of research attempted to use herbal medicines against COVID-19.

scholarly journals Anti-glycation activity of curcumin

2019 ◽  
Vol 73 ◽  
pp. 182-188
Author(s):  
Sabina Galiniak ◽  
Marek Biesiadecki ◽  
Bożena Czubat ◽  
Dorota Bartusik-Aebisher
Keyword(s):  
Curcuma Longa ◽  
Low Cost ◽  
Aldehyde Group ◽  
Secretory Cells ◽  
Therapeutic Effects ◽  
Active Inhibitor ◽  
Beneficial Effects ◽  
Wide Range

Curcumin, a compound belonging to the group of polyphenols with a characteristic yellow-orange color, is the most active ingredient of the long-leaved Curcuma longa L. and the ingredient of seasoning mixes, including curry spices. Due to its antioxidant, anti-inflammatory and anti-cancer properties, it has a wide range of therapeutic effects and has been studied for many years. Curcumin has enormous potential in preventing many diseases due to the widely described benefits of its use, it is non-toxic and additionally. Therapy with curcumin is low cost. Currently, many studies focus on the anti-glycation activity of curcumin, which could be used as an active inhibitor of glycation, i.e. a non-enzymatic process of combining a keto or aldehyde group of sugar with a free amino group of a protein. Finally, heterogeneous end products of advanced glycation are formed in the multistage and complicated glycation reaction. Formation of glycation products is intensified with age, as well as in various disease states, including diabetes or neurodegenerative diseases. Many literature data describe the role of curcumin in the prevention and treatment of diabetes. It is known that polyphenol has beneficial effects on hyperglycemia, insulin resistance and regeneration of secretory cells of pancreatic islets. It seems that addition of curcumin, the main ingredient of curry spice, to food could help people prevent the development of lifestyle diseases, including diabetes and its complications. The article presents the current state of knowledge on the curcumin anti-glycation properties in vitro as well as in vivo.

scholarly journals Therapeutic Effects of Nigella Sativa Linn (Black Cumin) on Candida albicans Vaginitis

2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Farzaneh Adiban Fard ◽  
Shahnaz Tork Zahrani ◽  
Alireza Akbarzadeh Bagheban ◽  
Faraz Mojab
Keyword(s):  
Candida Albicans ◽  
Nigella Sativa ◽  
Therapeutic Effects ◽  
Black Cumin

scholarly journals PHARMACEUTICAL SIGNIFICANCE OF NIGELLA SATIVA L., A WONDER HERB

2021 ◽  
Vol 3 (4) ◽  
pp. 04-13
Author(s):  
Irfat Ara ◽  
Mudasir Maqbool ◽  
Ginenus Fekadu ◽  
Tawseef Ahmad Hajam ◽  
Mohmad Amin Dar
Keyword(s):  
Chronic Headache ◽  
Nigella Sativa ◽  
Therapeutic Effects ◽  
Hepatic Toxicity ◽  
Gangetic Plains ◽  
Traditional System ◽  
Black Cumin ◽  
Traditional Remedies ◽  
Gastrointestinal Problems ◽  
Annual Herb

Nigella sativa L. (Family: Ranunculaceae; commonly known as black cumin) is an annual herb. N. sativa is cultivated and distributed all over India, especially in Punjab, Himachal Pradesh, Gangetic plains, Bihar, Bengal, Assam and Maharashtra. Among the traditional remedies, prescriptions of Nigella sativa for the treatment of various diseases are well-known since the prehistoric era. Therapeutic effects of Nigella sativa are thought to be due to nigellone and thymoquinone contents. The reported pharmacological properties include protection against disease and chemical-induced renal and hepatic toxicity, anti-inflammatory, analgesic, antipyretic, anti-microbial and antineoplastic activities. The oil decreases blood pressure, cholesterol, triglycerides, and glucose and increases respiration, hemoglobin and packed cell volume. In the traditional system of medicine, black cumin seeds are effective against cough, bronchitis, asthma, chronic headache, migraine, dizziness, chest congestion, dysmenorrheal, obesity, diabetes, paralysis, hemiplegia, back pain, infection, inflammation, rheumatism, hypertension and gastrointestinal problems such as dyspepsia, flatulence, dysentery, and diarrhea. In this review, we will elaborate about this wonder herb having miraculous effects.

scholarly journals Insights into the Protective Effects of Thymoquinone against Toxicities Induced by Chemotherapeutic Agents

Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 226
Author(s):  
Juveriya Farooq ◽  
Rokeya Sultana ◽  
Tahreen Taj ◽  
Syed Mohammed Basheeruddin Asdaq ◽  
Abdulkhaliq J. Alsalman ◽  
...  
Keyword(s):  
Nigella Sativa ◽  
Low Cost ◽  
Middle Eastern ◽  
Antioxidant Properties ◽  
Volatile Oil ◽  
Chemotherapeutic Agents ◽  
Herbal Remedies ◽  
Protective Effects ◽  
Drug Induced ◽  
Black Cumin

The drugs used to treat cancer not only kill fast-growing cancer cells, but also kill or slow the growth of healthy cells, causing systemic toxicities that lead to altered functioning of normal cells. Most chemotherapeutic agents have serious toxicities associated with their use, necessitating extreme caution and attention. There is a growing interest in herbal remedies because of their pharmacological activities, minimal side effects, and low cost. Thymoquinone, a major component of the volatile oil of Nigella sativa Linn, also known as black cumin or black seeds, is commonly used in Middle Eastern countries as a condiment. It is also utilized for medicinal purposes and possesses antidiabetic, anti-cancer, anti-inflammatory, hepatoprotective, anti-microbial, immunomodulatory, and antioxidant properties. This review attempts to compile the published literature demonstrating thymoquinone’s protective effect against chemotherapeutic drug-induced toxicities.

scholarly journals A SIMPLIFIED LITERATURE-BASED REVIEW: PHYTOCHEMISTRY, PHARMACOLOGY, SAFETY PROFILE, NUTRITIONAL VALUE AND TRADITIONAL THERAPEUTIC EFFECTS OF NIGELLA SATIVA L. IN UNANI SYSTEM OF MEDICINE

2021 ◽  
Vol 14 (2) ◽  
Author(s):  
Shaheen Akhlaq ◽  
Shabnam Anjum Ara ◽  
Mohammad Fazil ◽  
Usama Akram ◽  
Bilal Ahmad ◽  
...  
Keyword(s):  
Safety Profile ◽  
Nigella Sativa ◽  
Chemical Compositions ◽  
Therapeutic Effects ◽  
Gulf Region ◽  
Black Cumin ◽  
Black Cumin Seed ◽  
Cumin Seed

Background: Nigella sativa L. or black cumin, belong to the family Ranunculaceae, has long been used traditionally, for food purposes and in traditional Unani medicines and is a native of the Arabian Gulf region, East Asia, Africa and Europe. It is a rich medicinal plant in bioactive compounds. Aim of the study: The aim of this review is to develop an overview of black cumin seed in the context of the status traditional Unani medicine ideology with the incorporation of ethno pharmacological uses, chemical compositions, pharmacological activities, safety profile with evidence-based approach. Materials and Methods: Information on Nigella sativa L. was obtained from published materials, including medicinal plants monographs, ancient and modern recorded classical texts, Unani pharmacopoeias and electronic databases such as Pub Med, Web of Science, Science Direct and Google Scholar. Results: Black cumin seed has been used in Unani traditional medical systems throughout history. The presence of thymoquinone is mainly responsible for its most of the medicinal properties. Moreover, the presence of vitamins, myristic acid, proteins, fats, fiber, amino acids and some trace metals are also reported in the seeds particularly used as a nutraceutical. Numerous in vivo and in vitro studies on pharmacological effects of Nigella sativa L. viz. antioxidant, anticancer, immuno-modulatory, antimicrobial, neuroprotective, cardio protective, gastro protective, anti-hypertensive, nephroprotective, hepatoprotective and anti-diabetic properties demonstrated positive effect against diabetes, hypertension, hypercholesterolemia, bronchitis, asthma, rheumatism, back pain, cancer, gastrointestinal disorders, and eczema etc. Conclusion: Contemporary researches on Nigella sativa L. support the views of Unani physicians for its use as a food and medicinal herb. Black cumin-based potential therapeutic agents need to be applied for a variety of diseases and the formulation of accepted functional foods with the aim to promote optimum health and lessen the risk of chronic diseases.

Effect of the Phytochemical Agents Against the SARS-CoV and Selected Some of them for Application to COVID-19: A Mini-Review

2020 ◽  
Vol 21 ◽  
Author(s):  
Muhammad Idrees ◽  
Shamshad Khan ◽  
Nazakat Hussain Memon ◽  
Zhiyong Zhang
Keyword(s):  
Medicinal Plants ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Basic Knowledge ◽  
Effective Control ◽  
Diverse Range ◽  
Strong Base ◽  
Vaccine Treatment ◽  
Medicinal Plant Extracts ◽  
Future Drug

Background: The aim of the present review is to provide basic knowledge about the treatment of Coronavirus via medicinal plants. Coronavirus (COVID-19, SARS-CoV, and MERS-CoV) as a viral pneumonia causative agent, infects thousands of people in China and worldwide. There is currently no specific medicine or vaccine available and it is considered a threat to develop effective novel drug or anti-coronavirus vaccine treatment. However, natural compounds to treat coronaviruses are the most alternative and complementary therapies due to their diverse range of biological and therapeutic properties. Methods: We performed an open-ended, English restricted search of Scopus database, Web of Science, and Pubmed for all available literature from Jan-March, 2020, using terms related to phytochemical compounds, medicinal plants and coronavirus. Results: The view on anti-coronavirus (anti-CoV) activity in the plant derived phytochemicals and medicinal plants give the strong base to develop a novel treatment of corona virus activity. Various phytochemicals and medicinal plant extracts have been revised and considered to be the potential anti-CoV agents for effective control and future drug development. We discuss some important plants (Scutellaria baicalensis, Psorothamnus arborescens, Glycyrrhiza radix, Glycyrrhiza uralensis , Lycoris radiate, Phyllanthus emblica, Camellia sinensis, Hyptis atrorubens Poit, Fraxinus sieboldiana, Erigeron breviscapus, Citri Reticulatae Pericarpium, Amaranthus tricolor, Phaseolus vulgaris, Rheum palmatum, Curcuma longa and Myrica cerifera) emerged to have broad spectrum antiviral activity. Conclusion: Nigella sativa has potent anti-SARS-CoV activity and it might be useful souce for developing novel antiviral therapies for coronaviruses.

scholarly journals A Review of Herbal Therapy in Multiple Sclerosis

2018 ◽  
Vol 8 (4) ◽  
pp. 575-590 ◽  
Author(s):  
Sina Mojaverrostami ◽  
Maryam Nazm Bojnordi ◽  
Maryam Ghasemi-Kasman ◽  
Mohammad Ali Ebrahimzadeh ◽  
Hatef Ghasemi Hamidabadi
Keyword(s):  
Multiple Sclerosis ◽  
Cannabis Sativa ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
New Drugs ◽  
Crocus Sativus ◽  
Therapeutic Effects ◽  
Oenothera Biennis ◽  
Multiple Sclerosis Disease ◽  
Promising Therapeutic Approach

Multiple sclerosis is a complex autoimmune disorder which characterized by demyelination and axonal loss in the central nervous system (CNS). Several evidences indicate that some new drugs and stem cell therapy have opened a new horizon for multiple sclerosis treatment, but current therapies are partially effective or not safe in the long term. Recently, herbal therapies represent a promising therapeutic approach for multiple sclerosis disease. Here, we consider the potential benefits of some herbal compounds on different aspects of multiple sclerosis disease. The medicinal plants and their derivatives; Ginkgo biloba, Zingiber officinale, Curcuma longa, Hypericum perforatum, Valeriana officinalis, Vaccinium macrocarpon, Nigella sativa,Piper methysticum, Crocus sativus, Panax ginseng, Boswellia papyrifera, Vitis vinifera, Gastrodia elata, Camellia sinensis, Oenothera biennis, MS14 and Cannabis sativa have been informed to have several therapeutic effects in MS patients.

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