scholarly journals Association of Serum Albumin Level in Predicting of Preeclampsia among Pregnant Women in Dhaka City of Bangladesh

2019 ◽  
Vol 6 (2) ◽  
pp. 83-86 ◽  
Author(s):  
Taslima Begum ◽  
Md Anwar Habib ◽  
Shipra Chaudhury ◽  
Hasina Akter ◽  
Tahmida Firdousi ◽  
...  

Background: Serum albumin level is very important during the pregnancy for the good outcome of delivery. Objective: The purpose of the present study was to see the association of serum albumin level in predicting of preeclampsia among the pregnant women. Methodology: This descriptive cohort study was conducted in the OPD of the Department of Obstetrics and Gynaecology at Rajshahi Medical College Hospital, Rajshahi, Bangladesh from January 2013 to December 2014 for a period of two (2) years. This study was carried on pregnant woman attending in outdoor department of Gynaecology, Rajshahi Medical College Hospital, Rajshahi, Bangladesh before 20 weeks of pregnancy who were healthy normotensive primigravidae with singleton pregnancy. Healthy normotensive primigravidae with singleton pregnancy were enrolled in this study before 20th weeks and were followed up after 28th weeks of pregnancy. The data of serum albumin in gm/dL before 20th weeks and after 28th weeks of pregnancy were collected. Result: A total number of 75 pregnant women were finally included in this study. PE was identified in 12(16%) women out of 75 patients on the basis of one or more following parameters. Mean serum albumin in 1st visit was 3.84±0.41 gm/dL. No association was found between development of preeclampsia and levels of serum albumin in early trimester of pregnancy (p=0.960). Conclusion: In conclusion serum albumin level is not a predictor of development of preeclampsia among the pregnant women in early stage. Journal of Current and Advance Medical Research 2019;6(2):83-86

2019 ◽  
Vol 16 (2) ◽  
pp. 54-59 ◽  
Author(s):  
Taslima Begum ◽  
Khr Md Shahjahan Ali ◽  
Shafeya Khanam ◽  
Md Anwar Habib ◽  
Shipra Chaudhury ◽  
...  

Background: The clinical profiles and urinary albumin are very important for the prediction of preeclampsia among the pregnant women. Objective: The purpose of the present study was to assess the clinical and demographic profiles as well as the urinary albumin for the prediction of preeclampsia among the pregnant women. Methodology: This cohort study was conducted in the OPD of the Department of Obstetrics and Gynaecology at Rajshahi Medical College Hospital, Rajshahi, Bangladesh from January 2013 to December 2014 for a period of two (2) years. This study was carried on pregnant woman attending in outdoor department of Gynaecology, Rajshahi Medical College Hospital, Rajshahi, Bangladesh before 20th weeks of pregnancy who were healthy normotensive primigravidae with singleton pregnancy. The details demographic profiles, edema were collected from the study population. Urinary albumin was estimated before 20th weeks and after 28th weeks of pregnancy. Result: In the present study, 75 women were included; all were before 20th weeks of pregnancy without any complication or any risk factor for developing PE. Among the study group incidence of PE was 16%. The population are 24(32.0%) low, 31(41.3%) middle and 20(26.7%) high in socio economic conditions. Education level of study population was 45% completed primary education level, illiterate (27%) and secondary education (28%). Edema was absent in 1st visit, in 2nd visit 6(+), 6(++) present who developed PE, 18(+) present who did not develop PE. Edema was absent in 1st visit and (+) 6(50.0%) and (++) in 6(50.0%) present who developed PE in 2nd visit. Urine albumin in 1st visit nil in 6(50.0%), trace in 3(25.0%) and (+) in 3(25.0%) who developed PE. Conclusion: In conclusion housewife living in urban area in middle income socioeconomic condition are the most commonly presented with preeclampsia and urinary albumin is the most commonly detected in the pregnant women presented with preeclampsia Journal of Science Foundation 2018;16(2):54-59


2020 ◽  
Vol 7 (1) ◽  
pp. 12-16
Author(s):  
Naheed Fatema ◽  
Zannatul Ferdosh ◽  
Sherajum Munira ◽  
KAM Mahbub Hasan ◽  
Nasim Iftekhar Mahmud ◽  
...  

Background: Management of ectopic pregnancy is very crucial issue for the survival of the patients. Objective: The purpose of the present study was to observe the surgical management and per-operative findings of women with ectopic pregnancy. Methodology: This cross-sectional study was carried out in the inpatient Department of Obstetrics and Gynaecology at Bangladesh Medical College Hospital, Dhaka, Bangladesh from January 2009 to December 2009 for a period of one (1) year. All clinically suspected cases of ectopic pregnancy within the reproductive age admitted in the department of Obstetrics and Gynaecology at the Bangladesh Medical College Hospital, Dhaka were included in the present study. In most of the cases, laparoscopy or laparotomy was done to confirm the diagnosis and manage the cases. Result: A total number of 48 cases of ectopic pregnancy women were recruited for this study. The highest number of ectopic pregnancy occurs in the ampulla of the fallopian tube which was 27(58.3%) cases. The right tube had been found to be affected more than the left which was 30(62.5%) cases and 18(37.5%) cases respectively. Most of the patients were presented with ruptured tubal pregnancy which was 30(62.5%) cases. Opposite tube was normal looking in 25(52.1%) cases. Unilateral salpingectomy and salpingectomy with contra lateral tubectomy were operated in 32(66.7%) cases and 10(20.8%) cases respectively. Conclusion: In conclusion most of the ectopic pregnancy is occurred in the site of ampulla of fallopian tube in right side which are mostly surgically managed by unilateral salpingectomy. Journal of Current and Advance Medical Research 2020;7(1): 12-16


2020 ◽  
Author(s):  
Kosuke Kaji ◽  
Kiwamu Okita ◽  
Kazuyuki Suzuki ◽  
Ikuya Sato ◽  
Masaki Fujisawa ◽  
...  

Abstract Background Because covert hepatic encephalopathy (CHE) has been shown to affect the prognosis of cirrhotic patients, early diagnosis of HE is a prerequisite for preservation of patients’ quality of life and for prophylaxis of overt HE. Currently, neuropsychological tests are used for the diagnosis of early-stage HE including CHE. However, it would be inefficient to apply them to all cirrhotic patients. Thus, some biomarkers correlated with the above diagnostic modalities are available for screening examination. The aim of this study was to identify a clinical parameter to predict impairment of cognitive function in cirrhotic patients with early-stage HE.Methods This exploratory data analysis was based on the data from 172 patients with cirrhotic or idiopathic portosystemic shunt (PSS) in phase II/III trials of rifaximin in Japan. Their data at baseline before treatment with rifaximin were utilized to analyze the relationship between cognitive dysfunction and different clinical parameters We Classification and regression trees (CART) were constructed to identify clinical profiles related to cognitive dysfunction, as indicated by the prolongation of time required for the number connection test (NCT-B).Results CART analysis detected age 65 years as the variable for the initial split, and serum albumin level was selected as the variable for the second split among patients aged ≤ 65 years. In 27 cirrhotic patients aged ≤ 65 years without PSS, receiver-operating characteristic curve analysis revealed that the optimal albumin level cutoff point was 3.05 g/dL, and the area under the curve was 0.80 for the prolongation of NCT-B time, which was higher than that of other HE-related parameters including the branched-chain amino acids-to-tyrosine ratio (0.46), the prothrombin time–international normalized ratio (PT-INR) (0.68), serum ammonia (0.61), and total bilirubin (0.69).Conclusions Lower serum albumin level as a clinical biomarker associated with impaired cognitive function is available as a screening examination for early-stage HE in cirrhotic patients aged ≤ 65 years without PSS before undergoing neuropsychological tests.


2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Tania Akbar ◽  
Kamrun Nessa ◽  
Sanjida khan ◽  
Mst Shahina Begum Shanta ◽  
Rahat Afza Chowdhury ◽  
...  

Author(s):  
Sofia Abubekhar Suhurban ◽  
Sujatha Thankappan Lekshmikutty ◽  
Mayadevi Brahmanandan ◽  
Sreekumary Radha

Background: Near misses are defined as pregnant women with severe-life threatening conditions who nearly die but, with good care or good luck survive. Because near miss situation occurs more frequently than maternal death, more comprehensive and statistically reliable analysis could be conducted to assess the quality of maternal care and to develop evidence-based management protocols. The objectives of this study were to evaluate the determinants of near miss maternal mortality in a tertiary referral Government medical college hospital in Trivandrum, Kerala.Methods: Case control study from a defined delivery population with three randomly selected pregnant women as controls for every case. Study was conducted at Department of Obstetrics and Gynecology, Medical College Hospital Trivandrum, Kerala, India. Study duration was one year. Study population were patients admitted in Obstetrics and Gynecology Department, fulfilling the WHO criteria of near miss.Results: Of the primary determinant factors of near miss in this study, preeclampsia contributed the main role, followed by hemorrhage and eclampsia. During the antenatal period, preeclampsia was the major determinant followed by eclampsia. Hemorrhage was the major determinant in intra op /intra natal cases and next was eclampsia. Postpartum hemorrhage, eclampsia and preeclampsia were the major determinants in post-partum /post op cases. Among the associated indicators assessed, low socioeconomic status, anaemia, high body mass index, referral status, placenta praevia and caesarean section were statistically significant.Conclusions: Detailed analysis of near miss cases helps in identifying risk factors. It helps in formulating preventive strategies, and helps us in tackling the delays in referral process.


2017 ◽  
Vol 11 (1) ◽  
pp. 25-28
Author(s):  
Farzana Akonjee Mishu ◽  
MA Muttalib

Background and objectives: Alteration of magnesium (Mg) and copper (Cu) concentrations in blood has been observed in normal pregnancy as well as in gestational diabetes mellitus (GDM). The present study was aimed to evaluate the serum Mg and Cu levels in Bangladeshi women with GDM in their second and third trimester of pregnancy.Methods: The study was conducted at Mymensingh Medical College Hospital from July 2013 to June 2014. Pregnant women, in their second and third trimester, attending the outpatient department of Obstetrics and Gynecology and the Department of Endocrinology of Mymensingh Medical College Hospital were enrolled by purposive sampling technique. GDM was diagnosed on the basis of oral glucose tolerance test (OGTT) as defined in WHO criteria 2013. Blood glucose was estimated by enzymatic GOD-PAP colorimetric method. The cut off value for fasting plasma glucose level was ?6.1 mmol/L or ?7.8 mmol/L 2 hours after glucose load. Serum Cu was estimated by 3, 5-DiBr-PAESA method and Mg by Xylidyl Blue-I Method as per manufacturer’s instruction.Results: A total of 172 pregnant women in their second and third trimester were enrolled. Out of 172 participants, 86 had GDM and 86 were normoglycemic (control). The mean age of GDM and control groups was 28.6±3.2 years and 27.3±3.1 years respectively. The BMI was 26.4±1.5 m/kg2 and 26.3±1.3 m/kg2. Serum Mg level was significantly low (p< 0.001) in 2nd and 3rd trimesters in GDM cases (1.39±0.26 mg/dl and 0.93±0.15 mg/dl) compared to control group (1.67±0.3 mg/dl and 1.67±0.31mg/dl). On the contrary, serum Cu levels in GDM cases were significantly (p<0.002) higher in both trimesters (224±333.8 ?g/dl and 243.91±6.89 ?g/dl) compared to those without GDM (220.1±7.6 ?g/dl and 234.9±4.6 ?g/dl). There was significant (p<0.001) increase of serum Cu levels in 3rd trimester compared to 2nd trimester in both GDM and non GDM cases.Conclusion: There was distinct alteration of serum Mg and Cu levels in GDM compared to normal pregnancy.IMC J Med Sci 2017; 11(1): 25-28


Author(s):  
Jeevankumar U. Yadav ◽  
Deepmala J. Yadav

Background: Globally there has been increased medicalization of pregnancy due to advances in technology. Ultrasonography examination during pregnancy has become an integral part of antenatal care throughout the world with advanced health care services.Methods: The cross-sectional study was conducted in pregnant women attending the ANC clinic of Obstetric department of D. Y. Patil Medical College Hospital, Kolhapur, Maharashtra, India for routine check up to know the awareness about ultrasonography among them. The study included 290 pregnant women. All were explained the purpose of study and assured confidentiality. Data has been collected from willing participants using pre-tested questionnaire in June-August 2015.Results: The study shows literacy was 87.6%, pregnancy above 20 years age 98.97% and most of them unskilled (83.4%), majority of middle social class (89%). Many (72.41%) pregnant women considered USG use to detect fetal anomalies while 27.93% considered for sex detection. Majority (93.1%) done USG in this pregnancy, of that more (43.45 %) in second trimester and mainly advised by doctors (91.03%). Nearly half of them (50.69%) considered its expensive procedure, 69.31% spent 200/- to 500/- rupees per USG, in spite 94.83% of them would recommend other pregnant women to undergo USG in pregnancy. 50.69%% of them opined it should be done twice in pregnancy. Almost 94.83% considered USG as safe and beneficial.Conclusions: Awareness regarding the uses of Ultrasonography during pregnancy and attitude towards it was found to be average. There is need to create more awareness in community about PCPNT act and its provisions. Also there is need of counselling about the safety, utility and frequency of USG during pregnancy to avoid misuse.


2011 ◽  
Vol 18 (01) ◽  
pp. 46-50
Author(s):  
QAMAR-UR- NISA ◽  
HABIB ULLAH ◽  
TANWEER AHMED SHAIKH ◽  
Miss Hemlata ◽  
Fatima Memon ◽  
...  

Objective: To audit indications and histopathological diagnosis of hysterectomies performed at Muhammad Medical College hospital, Mirpurkhas. Study Design: Retrospective study. Place and Duration of Study: Department of Obstetrics and Gynaecology and Department of Pathology, Muhammad Medical College Hospital, Mirpurkhas Sindh from January to December 2008. Methodology: Data regarding symptoms and indications of hysterectomies performed during this year were collected from files and patient records. Histopathological reports of those patients were collected from department of pathology. The results were analyzed by percentages. Results: A total of 145 hysterectomies were performed in 2008. Mean age of patients was 45years ranging from 35-60 years and parity ranges from 4 – 10. Most common presenting complaints were excessive menstrual blood loss in 97(67%) patients, followed by some thing coming out of vagina 28(19%). Most common pre-operative diagnosis of fibroid was made in 44 (33%) followed by uterovaginal prolapse in 28(19%) and dysfunctional uterine bleeding (DUB) in 18(12%) of patients. Regarding histopathological diagnosis chronic cervicitis was the most commonly diagnosed pathology in 45 (31%) followed by fibroid in 25(17%) cases. Conclusions: A yearly audit should be conducted in every institute to collect data and to analyze the pattern of indication and lesions found on histopathological examination. 


2016 ◽  
Vol 28 (2) ◽  
pp. 82-87
Author(s):  
Shahela Nazneen ◽  
Farhana Begum ◽  
Shakila Nargis

Objective: To find out the sociodemographic characteristics, complications of pregnant woman with premature rupture of membrane (PROM) and asses the outcome of it.Materials and Methods: This prospective study was carried out at the department of Obstetrics & gynaecology of Comilla Medical College Hospital (CoMCH) from January 2009 to December 2009. All pregnant women admitted with PROM during this period were taken as study population. After taking proper history they were categorized as term or preterm PROM on the basis of duration of gestation estimated from 1st day of last menstrual period (LMP), previous antenatal records, clinical examination & also previous ultrasonography (USG) reports. Out of sociodemographic characteristics age distribution and gravidity were noted. Diagnosis was done on the basis of examination and investigations. All the women with PROM were then followed up, management was given according to protocol and caesarean section was performed according to indication. Birth weight and Apgar score of newborns were noted after delivery.Results: There were 198 cases of PROM recorded among 3142 admitted obstetrical patients over one year period. The hospital incidence of PROM was found to be 6.3%. Among them, 57.6% patients were admitted at term and 42.4% patients came before 37 completed weeks of gestation. Most of the pregnant women were between 20-24 years of age (54%), 41% were primigravida (59%) were multigravida. About 48.5% women presented with different complications associated with PROM. Among which 15.7% patients had oligohydramnios, 8.5% patients presented with chorioamnionitis suggested by culture report of high vaginal swab. Urine for culture and sensitivity was also done. About five (5.2%) developed premature labour before 37th week of gestation. About 10% women developed obstetric complications (failed trial) associated with medical diseases. Seventy seven patients were delivered by caesarean section, 16.2% vaginally, 4.04% patients responded to conservative management and 2.5% patients were referred to tertiary centre for extreme prematurity with associated complicating factors. Most of the babies (38.4%) were born with birth weight between 2.1- 2.5kg and 10.3% babies were less than 1.5kg.Conclusion: Term PROM was more in comparison to PPROM and most of them were multigravida. Caesarean section rate was high. Most common complication of was subclinical urogenital infection (53%) next oligohydramnios (25%) & (13.5%) women presented with chorioamnionitis.Bangladesh J Obstet Gynaecol, 2013; Vol. 28(2) : 82-87


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