scholarly journals Comparison of Serum Lipid Profiles of Women with or Without Hormonal Contraceptives Users at a Tertiary Care Hospital in Dhaka City

2021 ◽  
Vol 18 (1) ◽  
pp. 19-24
Author(s):  
Kashifa Khatun ◽  
Naznin Rashid Shewly ◽  
Shimul Akter ◽  
Sultana Afroj ◽  
Nilofar Yasmin ◽  
...  
Keyword(s):  
Serum Lipid ◽  
Low Dose ◽  
Lipid Profiles ◽  
Hormonal Contraceptives ◽  
Control Group ◽  
Case Group ◽  
Care Hospital ◽  
Cholesterol Levels ◽  
Significant Difference ◽  
History Of

Background: Both oral and injectable hormonal contraceptives are the most popular type of birth control measures used in Bangladesh. Objective: The purpose for the present study was to see the effects of hormonal contraceptives on serum lipid profiles. Methodology: This was case-control study which was carried out in the Department of Obstetrics & Gynaecology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2004 to December 2005 for eighteen (18) months. Women of reproductive age group who had given the history of taking low-dose OCP containing 30 meg EE plus 150 meg LNG were included as case group and women who were presented without the history of hormonal contraceptives use were included as control group. Blood was collected from each woman in fasting state and serum was sent for estimation of serum lipids profiles like serum triglycerides, total cholesterol, LDL and HDL. Result: The study included 40 women (control) who were not using OCP and 40 women (case) who were using OCP for more than one year. Comparison of age between control (31.75±4.85 years) and case (30.43±5.44 years) groups showed no significant difference (p>0.05). No significant difference with raised cholesterol levels (207.50±3.54 and 254.71± 45.54 mg/dl) was reported. Comparison of normal (136.16±39.46 and 154.05±35.33 mg/dl) and raised (229.00±24.52 and 246.32±35.98 mg/dl) triglyceride levels between control and case groups did not statistically significant. Comparison of normal and raised HDL levels did not show statistically any significant difference in control (32.07±3.02 mg/dL) and case (32.48±1.76 mg/dL) groups. Mean (±SD) of normal and raised levels of LDL was significantly high in case group. Normal LDL level was 82.71±26.82 and 111.05±15.40 mg/dl and raised LDL level was 138.55±3.03 and 188.82±40.37 mg/dL. Conclusion: In conclusion use of low-dose OCP containing 30 meg EE plus 150 meg LNG significantly increases serum cholesterol, serum triglyceride and LDL-cholesterol levels but not HDL-cholesterol. Journal of Science Foundation, January 2020;18(1):19-24

scholarly journals Low detection rate of advanced neoplasia within 5 years after polypectomy of small serrated adenoma

2019 ◽  
Vol 95 (1122) ◽  
pp. 187-192 ◽  
Author(s):  
Duochen Jin ◽  
Hailong Cao ◽  
Bikash Kumar Shah ◽  
Danfeng Chen ◽  
Yujie Zhang ◽  
...  
Keyword(s):  
Control Group ◽  
Case Group ◽  
Surveillance Colonoscopy ◽  
Surveillance Period ◽  
Serrated Adenoma ◽  
Advanced Neoplasia ◽  
Significant Difference ◽  
Negative Findings ◽  
History Of ◽  
Low Prevalence

AimPatients with small serrated adenomas (SAs) (<10 mm) often undergo surveillance colonoscopy before the routine recommended time. We aimed to determine the appropriate surveillance intervals following polypectomy of small SAs for symptomatic patients.MethodWe retrospectively reviewed the data of 638 patients, including 122 cases and 516 controls. Subjects in the case group had small SAs at baseline colonoscopy, including sessile SA/polyps and traditional SAs, while subjects in the control group had negative findings. All patients underwent at least one surveillance colonoscopy during the following 5 years.ResultsThere was no significant difference in the incidence rate of advanced neoplasia between the two groups over a 5-year duration (3.6% vs 2.6%, p=0.455). Moreover, both groups also showed a low prevalence of SA formation over 1–5 years (3.6% vs 1.0%, p=0.145). Patients with baseline SA tended to undergo the first surveillance colonoscopy earlier than those without adenoma (≤1 year vs 1 to ≤3 years). Seventy-one (11.1%) of the total included subjects underwent inadequate initial colonoscopy, and 30 (42.3%) underwent early surveillance of adenoma formation within 1 year. Patients with a family history of colorectal cancer (OR 4.69, 95% CI 1.48 to 14.71, p=0.017) or inadequate baseline colonoscopy (OR 3.17, 95% CI 1.202 to 8.409, p=0.035) were at a higher risk of metachronous adenoma formation during the surveillance period.ConclusionPatients with small SAs at baseline gain little benefit from follow-up of colonoscopy within 5 years after complete polypectomy.

scholarly journals Comparison on cognitive performance among schoolchildren born prematurely according to the presence of intracranial hemorrhage in the neonatal period

2019 ◽  
Vol 19 (3) ◽  
pp. 513-520
Author(s):  
Marcia Salim de Martino ◽  
Leandro Lopes Fernandes Alves ◽  
Cristina Ortiz Sobrinho ◽  
Adauto Dutra Moraes Barbosa
Keyword(s):  
Cognitive Performance ◽  
Intracranial Hemorrhage ◽  
Neonatal Period ◽  
Tertiary Hospital ◽  
Control Group ◽  
Case Group ◽  
Cross Sectional ◽  
Neonatal Diagnosis ◽  
Significant Difference ◽  
History Of

Abstract Objectives: to compare the cognitive performance of schoolchildren born prematurely according to the presence of intracranial hemorrhage (ICH) during the neonatal period. Methods: a cross-sectional cohort study of schoolchildren between the ages of 6-8 years old, born prematurely with or without a history of neonatal ICH. Between January and December 2015, some children were followed up at the outpatient clinic of a tertiary hospital and underwent a cognitive evaluation by using the Wechsler Intelligence Scale for Children, Third Edition (WISC-III) and they were divided into two groups: those with no history of ICH (control group) and those with ICH (case group), confirmed by a transfontanelar ultrasound in the prenatal period. Results: 39 schoolchildren were included, 21 cases and 18 controls. There was no difference in gestational age or chronological age at evaluation between the groups. Also there was no significant difference in subtest scores between the groups. Conclusions: WISC-III evaluated the cognitive performance in children, born preterm, aged 6-8 years old, and had neonatal ICH did not differ from those of their peers without a history of ICH. These findings suggest that, in preterm infants, a neonatal diagnosis of ICH may not be associated with cognitive performance at school age and this should be investigated through a longitudinal study.

scholarly journals Association among Thyroid Dysfunction, Asthma, Allergic Rhinitis and Eczema in Children with Alopecia Areata

2017 ◽  
Vol 5 (3) ◽  
pp. 305-309 ◽  
Author(s):  
Javad Ghaffari ◽  
Ghasem Rahmatpour Rokni ◽  
Armaghan Kazeminejad ◽  
Hosein Abedi
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Alopecia Areata ◽  
Allergic Diseases ◽  
Control Group ◽  
Case Group ◽  
Control Groups ◽  
Significant Difference ◽  
History Of ◽  
And Control

BACKGROUND: Alopecia areata is a non-scarring hair loss, which typically starts quickly. Atopy is one of the possible predisposing risk factors for this condition.AIM: This study aimed to evaluate the prevalence of thyroid disease, atopic dermatitis and allergic diseases in children with alopecia areata and compare the results with healthy individuals.METHODS: This case-control study was conducted on 50 patients with alopecia areata, diagnosed by a dermatologist, and 150 healthy individuals as the control group. Participants filled the questionnaires, and necessary tests were performed.RESULTS: In this study, the mean age of the participants was 2.55 ± 14.26 and 3.19 ± 11.92 in the case and control groups, respectively. Prevalence of asthma was 22% in the case group and 12.5% in control group (P = 0.109). Also, allergic rhinitis and eczema were observed in 20% and 22% of the subjects of the case group, whereas they were reported to be 8% and 10% in the control group (PV = 0.03 and 0.175, respectively). Moreover, 28% and 8% of the participants in the case and control groups had a family history of atopy and allergic disorders, respectively (P = 0.046). A significant difference was observed between the two groups regarding gender, type of delivery and contact with animals.CONCLUSIONS: According to the results of this study, a significant association was observed between the prevalence of alopecia areata and atopic conditions, such as allergic rhinitis and history of atopic dermatitis.

scholarly journals Association of Cytomegalovirus (CMV) Infection with Guillain- Barré Syndrome (GBS) In Tertiary Care Hospital (BSMMU) of Bangladesh

2013 ◽  
Vol 29 (2) ◽  
pp. 88-97
Author(s):  
Nuruddin Mohammad Eusuf ◽  
Md Rezaul Karim Khan ◽  
Abu Nasir Rizvi ◽  
Sheikh Abdul Kader ◽  
Abu Jafor Md Salahuddin ◽  
...  
Keyword(s):  
Guillain Barre Syndrome ◽  
Control Group ◽  
Case Group ◽  
Care Hospital ◽  
Cmv Infection ◽  
Hepatic Diseases ◽  
Guillain Barré Syndrome ◽  
History Of ◽  
Guillain Barré ◽  
Inpatient Department

Background: Guillain-Barré syndrome (GBS) usually preceded by infections, in particular cytomegalovirus (CMV). It may occur by primary infection, reinfection or by reactivation of CMV. Objective: The aim of the present study was to evaluate the association of Guillain-Barré syndrome (GBS) with Cytomegalovirus (CMV) infection. Methodology: This case control study was carried out in the indoor and outpatient Department of Neurology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from 1st January 2010 to 31st December 2011 for the duration of two years. All patients with GBS, who attended in neurology OPD or inpatient department at BSMMU during the study period, fulfilling the inclusion and exclusion criterias were included in this study. Age & sex matched volunteers, patients attendants, patients other than GBS who were nondiabetic, had no renal or hepatic diseases or family history of polyneuropathy were included in control group. Results: A total number of 78 respondents of which 39 patients were taken as cases and rest 39 were taken as controls who appeared in neurology OPD or inpatient department at BSMMU during the study period, fulfilling the inclusion and exclusion criterias were included in this study. The mean age ± SD of case and control groups were 30.82 ± 12.56 and 31.00 ± 12.77 years respectively (p=0.950). In case group the history of respiratory tract infection was present in 46.2% cases and absent in control group (p=0.001). In case group the history of gastroenteritis was present in 28.2% cases and absent in control group (p=0.001). In case group the history of fever was present in 30.8% cases and absent in control group (p=0.001). Anti-CMV IgM antibody was positive in 5.1% cases. Four fold rise of IgG in case group was present in 10.3% cases and absent in control group (p=0.040). Confirmed CMV infected GBS cases were 15.4% and absent in control group (p=0.011). Conclusion: The findings of this study permit to conclude that there is a significant association of Guillain-Barré syndrome (GBS) with Cytomegalovirus (CMV) infection. Bangladesh Journal of Neuroscience 2013; Vol. 29 (2) : 88-97

scholarly journals Lipid profiles among Plasmodium falciparum infected, non malarial febrile patients and volunteers

2018 ◽  
Vol 5 (3) ◽  
pp. 556
Author(s):  
Bipin K. Kullu ◽  
Chakradhar Majhi ◽  
Butungeshwar Pradhan ◽  
Deepak K. Swain
Keyword(s):  
Plasmodium Falciparum ◽  
Healthy Volunteers ◽  
Total Cholesterol ◽  
Falciparum Malaria ◽  
Serum Lipid ◽  
Lipid Profiles ◽  
Control Group ◽  
Metabolic Derangement ◽  
Cholesterol Levels ◽  
Time Of Admission

Background: Acute falciparum Malaria infected patients show wide ranges of metabolic derangement including changes in serum lipid profiles. The exact mechanisms of this derangement in serum lipid profiles are still poorly understood. Objective was to study the lipid profiles among acute plasmodium falciparum infected patients.Methods: It was a Prospective observational comparative study. A total of 100 patients were consecutively taken in the study. Fifty Non- malaria febrile cases and 50 healthy volunteers were taken as control group. Baseline lipid profiles were estimated in all cases at the time of admission and at the end of one week. Data were collected and analyzed.Results: There were 100 diagnosed cases of falciparum malaria and 50 non malarial febrile and 50 healthy volunteers taken as control group. Complications was present in 50 and 50 were uncomplicated. Serum total cholesterol, HDL and LDL levels were significantly low in falciparum malaria patients, and serum TG and VLDL levels were higher than control. There were no significant changes in mean serum lipids profiles in survived and deaths cases.Conclusions: The derangement in lipid profiles in falciparum malaria was characteristic and specific for the disease. Characteristic changes were lower HDL, LDL and total cholesterol levels and higher TG and VLDL levels in comparison to control groups. Changes are more pronounced in complicated falciparum Malaria and persisting till the end of the week. These findings may be of diagnostic and prognostic value.

Cholesterol concentrations in violent and non-violent women suicide attempters

2003 ◽  
Vol 18 (1) ◽  
pp. 23-27 ◽  
Author(s):  
J. Vevera ◽  
I. Žukov ◽  
T. Morcinek ◽  
H. Papežová
Keyword(s):  
Suicide Attempts ◽  
Analysis Of Covariance ◽  
Cholesterol Concentration ◽  
Control Group ◽  
Impulsive Behavior ◽  
Suicide Attempters ◽  
Cholesterol Levels ◽  
Significant Difference ◽  
Lower Serum Cholesterol ◽  
History Of

AbstractThe aim of this study was to evaluate whether women with a history of violent suicide attempts have lower serum cholesterol concentrations than those who attempted suicide by non-violent methods. Our retrospective study used a case-control design to compare serum total cholesterol concentration, hematocrit, red blood cell count and body mass index (BMI) in women with a history of violent (n = 19) or non-violent (n = 51) suicide attempts and of non-suicidal controls (n = 70) matched by diagnosis and age. Analysis of covariance (ANCOVA) with age as the covariate was used to analyze differences in cholesterol levels in groups according to violence. Violence was found to be a significant factor (P = 0.016). Using the Scheffé test, a significant difference (P = 0.011) was revealed between the group of violent and non-violent suicide attempters and between the violent suicide attempters and the control group. Patients with a violent suicidal attempt have significantly lower cholesterol levels than patients with non-violent attempts and the control subjects. Our findings suggest that suicide attempts should not be considered a homogenous group. They are consistent with the theory that low levels of cholesterol are associated with increased tendency for impulsive behavior and aggression and contribute to a more violent pattern of suicidal behavior.

scholarly journals The usefulness of neutrophil to lymphocyte ratio in febrile seizure

2020 ◽  
Vol 7 (5) ◽  
pp. 985
Author(s):  
Pooja A. ◽  
Amitha Rao Aroor ◽  
Santosh T. Soans
Keyword(s):  
Febrile Seizure ◽  
Tertiary Care ◽  
Neutrophil To Lymphocyte Ratio ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Care Hospital ◽  
Retrospective Case ◽  
Lymphocyte Ratio ◽  
Significant Difference

Background: Febrile seizure is an event in infancy or childhood, usually occurring between 3 months and 5 years of age associated with fever but without evidence of intracranial infection. The aim of the study was to estimate the usefulness of neutrophil-to-lymphocyte ratio (NLR) in patients with simple and complex febrile seizures.Methods: Retrospective case control   study was done in a paediatric in patients admitted to tertiary care hospital.  Study period   was from January 2017 to December 2019. 200 children were analysed in the study. 100 out of 200 were under control group (febrile children without seizure). Remaining 100 were under case group (children with febrile seizure), 54 out of 100 children had   complex febrile seizure, 46 out of 100 had simple febrile seizure. NLR ratio was done in all children.Results: Total 200 children were analysed in this study.   High NLR ratio   was noted among the cases (87 out of 100) compared to control (30 out of 100) p value = <0.001. Among the cases CFS had high NLR ratio compared to SFS, however p value was not significant (0.072).Conclusions: Children with febrile seizure had high NLR ratio compared to those without seizures. However no significant difference was noted between those with simple febrile seizure and complex febrile seizure   However, larger trials are required   to assess whether higher NLR can be taken as an independent risk factor for febrile seizure.

scholarly journals Evaluation of the Relationship Between Childhood Asthma and Helicobacter pylori Sero-Prevalence

2019 ◽  
Author(s):  
Rasoul Nasiri ◽  
Pedram Ataee ◽  
Azad Abdi ◽  
Ghobad Moradi ◽  
Borhan Moradveisi ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Cigarette Smoke ◽  
Childhood Asthma ◽  
Control Group ◽  
Case Group ◽  
Significant Difference ◽  
History Of ◽  
H Pylori ◽  
And Control ◽  
The Relationship

In recent years, the prevalence of asthma and allergic rhinitis has increased in developed countries. Helicobacter pylori (H. pylori) infection can exacerbate asthma. The purpose of this study was to investigate the relationship between asthma and H. pylori seroprevalence in children. In this cross-sectional study, 100 children aged 5-15 years hospitalized in Besat hospital in Sanandaj were investigated from 2015 to 2016. Fifty children with asthma were considered as the case group and 50 non-asthmatic children as the control group. The questionnaires were completed, including demographic information, history of asthma, exposure to cigarette smoke, and family history of gastric and duodenal ulcers. Blood samples were collected from the children, and the serum level of specific antibodies (IgG) of H. pylori was measured. There were 42 and 31 boys in the case and control group, respectively. The mean age in the case group was 8.12±2.29 and in the control group was 8.9±2.52 years. In the case group, 48% were exposed to cigarette smoke and in the control group, 18%. There was a statistically significant difference between the groups in terms of gender and exposure to cigarette smoke (P=0.001 and P=0.013, respectively). There was no significant difference between the case and control groups in terms of H. pylori seroprevalence. (P=0.211). There was no significant association between asthma and H. pylori seroprevalence. (P=0.22). According to our study, there no correlation between childhood asthma and H. pylori seroprevalence. © 2019 Tehran University of Medical Sciences. All rights reserved. Acta Med Iran 2019;57(5):299-302.

HUBUNGAN TUNGAU DEBU RUMAH, PAPARAN ASAP ROKOK DAN RIWAYAT PENYAKIT KELUARGA TERHADAP KEJADIAN ASMA BRONKIAL PADA ANAK USIA 5 – 10 TAHUN DI WILAYAH KERJA PUSKESMAS LEMPAKE KOTA SAMARINDA TAHUN 2016

2018 ◽  
Vol 3 (1) ◽  
pp. 1
Author(s):  
Sri Evi New Yearsi Pangadongan ◽  
Agustina Rahyu ◽  
Selvy Pasulu
Keyword(s):  
Cigarette Smoke ◽  
Bronchial Asthma ◽  
Sampling Technique ◽  
Total Sample ◽  
Control Group ◽  
Case Group ◽  
Chi Square ◽  
History Of ◽  
Weather Changes ◽  
And Gender

Bronchial Asthma generally starts from childhood which is condition where respiration channel experiences constriction because of hyperactivity with some specific stimulation which cause inflammation. Some risk factors are smoking exposure of cigarette smoke, weather changes, mite on house dirt, pet and history of family sickness. The purpose of this research is to know Relation of mite on house dirt, exposure of cigarette smoke  and history of family sickness with bronchial asthma incident to child 5 – 10  years old on working area of Puskesmas Lempake Samarinda City in 2016. Method which used was analytic survey with Case Control approaching. The total sample was 36 children which consisted of 18 case group and 18 control group with matching by using age and gender which submitted with Purposive Sampling technique. Data Analysis used Chi Square with wrong degree α = 0,005. The result showed that there was relation of mite of house dirt (p = 0,006), history of family sickness (p = 0,001) and no relation with exposure of cigarette smoke (p = 0,370) with bronchial asthma incident to child 5 – 10 years old on working area of Puskesmas Lempake Samarinda City in 2016.

Breastfeeding Training through Role-Play and Effects on Mother-infant Attachment Behaviours: A Randomised Controlled Trial

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Farokh Saljughi ◽  
Mitra Savabi-Esfahani ◽  
Shahnaz Kohan ◽  
Soheila Ehsanpour
Keyword(s):  
Pregnant Women ◽  
Maternal Employment ◽  
Controlled Trial ◽  
Role Play ◽  
Intervention Group ◽  
Control Group ◽  
Maternal Behaviour ◽  
Infant Attachment ◽  
Significant Difference ◽  
History Of

Mother-infant attachment is an intimate, lasting and satisfying relationship that leads to better cognitive, emotional and social growth of the infant. The aim of this study was to determine the effects of breastfeeding training by role-play on mother-infant attachment behaviours. This research was a randomised clinical trial (parallel design). Inclusion criteria were: no history of mental disorders; ability to read and write the Persian language to complete the questionnaire; no history of drug and tobacco intake in primigravida women. The sample comprised 100 pregnant women (in 2 groups), selected through simple random sampling at healthcare centres. The researcher reviewed prenatal care registries of selected healthcare centres and extracted the names of pregnant women in their early third trimester. The data were imported into randomisation software. The control group received routine breastfeeding training, while the intervention group received routine training together with training through role-play. The data collection tool was the Maternal Behaviour Inventory Questionnaire. Consequently 75 samples were analysed in SPSS16. Independent t-tests and chi-square tests were used to examine the difference between the two groups. Results showed that the mean score of mother-infant attachment one week after delivery was significantly higher in the intervention group in comparison to that in the control group (p<0.001). No significant difference was observed between the two groups in maternal age, age of marriage, neonatal gender, maternal employment and education, number of parity, and number of abortions (P>0.05). Since breastfeeding training through role-play could affect mother-infant attachment, it is suggested that this type of training should be provided for pregnant women to promote mother-infant attachment and exclusive breastfeeding.

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