scholarly journals Association of Low Serum Cholesterol With Hemorrhagic Stroke

KYAMC Journal ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 147-152
Author(s):  
ABM Khairul Hasan ◽  
Jalal Uddin ◽  
Safayet Ahmed ◽  
Kazi Shihab Uddin ◽  
Muhammad Alamgir Mandal ◽  
...  

Background: Stroke is the second cause of death and third cause of disability in worldwide so control of risk factor is the best option for prevention of stroke and stroke related disability. Objectives: The study is to know the relation of low serum cholesterol with hemorrhagic stroke. Materials and Methods: This Study is a case control study carried out at Neurology and Medicine ward Mymensingh Medical college hospital (MMCH) from july2017 to December 2018 to see the association of low serum cholesterol with hemorrhagic stroke. A total number of 120 subjects more than 18 years were considered for the study. Among them 60 were study group and 60 were control group. The study population has been selected following some exclusion and inclusion criteria. Results: Result showed that hemorrhagic stroke was more in male than female, common after the age of 60 years. Lower middle classes are more sufferers. Hypertension was 76.7% of study group and serum cholesterol was significantly lower in study group than the control group. Conclusion: This study found that the serum total cholesterol level of study group is less than that of the healthy control group and the difference is statistically highly significant (p< 0.001). So it can be concluded that low serum cholesterol is associated with hemorrhagic stroke. KYAMC Journal. 2021;12(3): 147-152

1970 ◽  
Vol 2 (1) ◽  
pp. 22-25
Author(s):  
Mahamuda Begum ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Shamim Ara ◽  
Gul Newaz Begum

In pregnancy, anaemia has a tremendous effect on the placenta. Maternal anaemia increases the volume of the placenta. Foetal hypoxaemia usually develops as a consequence of maternal anaemia, due to lower haemoglobin concentration, and stimulates placental growth. A prospective study was carried out in the Department of Obstetrics & Gynaecology, Dhaka Medical College Hospital and Maternal and Child Health Training Institute (widely known as Azimpur Maternity), Dhaka, Bangladesh, from August 2005 to June 2006 on 60 Bangladeshi women who were within 35-40 weeks of gestation. Among them, 20 had normal uncomplicated pregnancies (considered as control group or group A) and another 27 had pregnancies with mild anaemia (considered as group B1) and 13 had pregnancies with moderate anaemia (considered as group B2). Severe anaemic (considered as group B3) mother was not found during the period of collection of data for this study. The mothers were selected as who were suffering from antenatal anaemia i.e. having heamoglobin level <10 gm/dl (mild, if <10 gm/dl; moderate, if <8 gm/dl; and severe, if <6 gm/dl) and control i.e. having heamoglobin level ≥10 gm/dl. The placentae of the mothers were collected after delivery and their volume were measured by water displacement method and recorded. The present study showed that mean volume of placenta in group A, group B1 and group B2 were 444.00±38.37, 472.59±17.34 and 485.38±24.62 ml respectively. The difference between group A & B1, and A & B2 were found statistically significant. The volume of the placenta was found to increase with ascending grade of antenatal naemia of mothers in comparison to that of normal pregnancy. Key Words: Antenatal Anaemia; Maternal Anaemia; Volume of Placenta DOI: 10.3329/akmmcj.v2i1.7467 Anwer Khan Modern Medical College Journal 2011; 2(1): 22-25


2019 ◽  
Vol 10 (2) ◽  
pp. 91-94
Author(s):  
Fatema Ashraf ◽  
Sania Sultana ◽  
Tasdik Hasan ◽  
Hamida Pervin ◽  
Fahima Mustanzid ◽  
...  

Background: GDM is a public health issue, affecting mostly the South East Asian region, as well in Bangladesh (prevalence 9.7% - 12.9%). It has a significant adverse impact on maternal and foetal outcome. So it needs to be addressed energetically to avoid maternal and foetal morbidity and mortality. Also it will contribute a lot to the pool of Type II Diabetes as substantial number of GDM mother and their offspring may develop type II DM in near future. Self-management of GDM is well-known globally but there is still lacking in adequate handling of diabetes by the patients themselves. Nevertheless the lacking can be minimized through ‘Patient Empowerment’ by clear understanding of the disease and its consequences along with intense learning, training, monitoring and evaluation of the clients involved. Also it will help in emotional stability of the client which is an essential component of diabetes management during pregnancy. The innovative strategy may contribute significantly in GDM management at low cost in a resource constraint setting. Objective: To find the effectiveness of ‘patient empowerment’ promoting better self-management of GDM. Methodology: This quasi experimental study was done on 96 cases (48 in each group) by purposive sampling technique at Shaheed Suhrawardy Medical College Hospital (ShSMC) as study group & Rajshahi Medical College Hospital (RMCH) as control group, from August 2012 – August 2015. Both group were matched of age, parity, education and income. Ethical clearance was taken from ethical committee of both ShSMC and RMCH Result: In the study group good glycemic control achieved with diet & exercise (75%) and Insulin required in only 25% cases, while in control group Insulin given in 75% cases. In the study group NVD (67%) were more than control group (33.3%). There were no obstructed labour in study group but control group (12.50%). Majority of the study group (74.6%) had no or minimum antenatal complication, in comparison to control group (74.66%). Regarding Neonatal outcome, neonatal resuscitation required none in study group but 12 (25%) in control group. So, overall adverse outcome observed less in study group than control group Conclusion: Patient empowerment can be an effective tool to manage GDM cases with an outcome of good control of blood sugar; less antenatal, intrapartum and post natal complications, good foetal and neonatal outcome and low requirement of insulin. J Shaheed Suhrawardy Med Coll, December 2018, Vol.10(2); 91-94


2021 ◽  
Vol 29 (1) ◽  
pp. 29-32
Author(s):  
Farhana Rahman ◽  
Qazi Shamima Akhter ◽  
Nahid Yeasmin ◽  
Farhana Sultana ◽  
Sabira Tabassum ◽  
...  

Background: Hair loss is a worldwide problem with significant prevalence in the developed countries. Although many pathophysiological factors have been involved in the development of hair loss, its etiology is still unclear. Trace elements. Objective: To assess duration of hair loss with serum iron level in alopecia. Methods: This cross sectional study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka during January 2017 to December 2017. Serum iron level was estimated by flame atomic absorption spectrophotometry of thirty five newly diagnosed hair loss patients aged 18 to 45 years were study group and thirty five ages, sex and BMI matched healthy subjects were control group. Both male and female was assessed by analyzing time. In this study, the duration of hair loss was 1 to 18 months. Duration of hair loss in study group was divided in two groups such as ≤2 months and >2 months. Patients were selected from Department of Dermatology and Venerology, Dhaka Medical College Hospital, Dhaka. For statistical analysis Unpaired Student’s‘t’ test, Chi square tests and Pearson’s correlation coefficient (r) tests were performed. Results: In this study, serum iron level showed negative correlation with the duration of disease in study group. Conclusions: From this study, it is concluded that serum iron deficiency is associated with duration of hair loss patients. J Dhaka Medical College, Vol. 29, No.1, April, 2020, Page 29-32


2019 ◽  
Vol 19 (1) ◽  
pp. 17-20
Author(s):  
Mohammad Ashraf Uddin Khan ◽  
Md Alamgir Hossain Sikder ◽  
Arif Salam Khan ◽  
Md Ashiqur Rahman ◽  
Ahmed Sarni Al Hasan ◽  
...  

Objectives: To find out the efficacy of single dose antibiotic vs multiple dosesin preventing wound infection following appendicectomy for uncomplicated appendicitis. Methods: A prospective comparative study was conducted in the Department of Surgery, Chittagong Medical college Hospital from January'2009 to June'2009. 100 patients with uncomplicated appendicitis who underwent appendicectomy during that period were included in this study. Among them 50 cases were included in study group ·(SG) who were given only single dose of combination drugs ( lnj. Cefuroxime + lnj. Metronidazole).ln rest of the 50 cases (CG), antibiotics were continued for 7 days postoperatively. Result: Maximum incidence of acute appendicitis was in the 2nd and 3rd decade of life with male preponderance .Rate of wound infection in the study group and control group was 4% and 2% respectively which was not statistically significant .The duration of antibiotic therapy had no significant effect on the length of hospital stay between the two groups ; 2.48 days vs 2.9 days [mean + s.d. 69.6 # 16.8 hours ] in the study and control group respectively, though treatment cost was higher in control group in comparison to the study group . Conclusion: Single dose of preoperative antibiotics is adequate for prevention of postoperative wound infection following appendicectomy for uncomplicated appendicitis. Journal of Surgical Sciences (2015) Vol. 19 (1) : 17-20


2020 ◽  
Vol 8 (1) ◽  
pp. 128-131
Author(s):  
K Mounisha ◽  
MU Jeevika ◽  
BG Mahesh ◽  
B Adarsh ◽  
KK Nirnay

Background: Neuroimaging provides essential information as evidence of previous injuries, specific abnormalities that could indicate a group or a particular disease in babies with global developmental delay. The objectives is to assess the difference of corpus callosal size in various regions of the corpus callosum in cases of children with developmental delay and to know the etiology using MRI. Subjects and Methods: My study includes 102 children between 1 to 6 years of age among which 51 children are cases having signs and symptoms of developmental delay and 51 children are controls i.e. healthy babies. They underwent MRI in the Department of Radiology, JJM Medical College, Davangere in whom corpus callosum is imaged on sagittal MR sections and its size is calculated in different regions. Results: Abnormalities of the corpus callosum like thinning and agenesis were observed in 55.5% (N=27) in the study group, and none of the patients in the control group. Partial corpus callosal agenesis was present in 3.9% of patients. Complete agenesis in 3.9% of patients. Thinning of the corpus callosum was seen in 45% of patients who were in the study group. Conclusion: The current study suggests that corpus callosal abnormalities, including brain changes, is useful in knowing the etiology of global developmental delay.


1970 ◽  
Vol 17 (2) ◽  
pp. 78-82
Author(s):  
S Kishwara ◽  
ASM Nurunnabi ◽  
M Begum ◽  
R Ahmed ◽  
S Ara

Context: The changes in volume of the placenta and its internal components are evident in different maternal diseases like preeclampsia. Postnatal examination of the placenta is an important method for assessing maternal and fetal condition in antenatal and perinatal periods and enriching practical knowledge.Study design: Cross-sectional descriptive type.Place and period of study: Department of Anatomy, Dhaka Medical College, Dhaka from August 2005 to June 2006.Materials & Methods: 54 human placentae from Bangladeshi women were collected from the Department of Obstetrics & Gynaecology of Dhaka Medical College Hospital and Sir Salimullah Medical College Hospital, of which 27 from normal uncomplicated pregnancies (control group) and another 27 from pregnancies complicated by preeclampsia (study group) where the patients were normotensive previously.Results: Both the proportional and absolute volume of placental parenchyma were found lower in preeclamptic women than those of normal pregnant women (P<0.001). But only in the absolute volume of non-parenchyma of the placenta, there was difference in between two groups (P<0.001), no difference found in relative volume (P>0.50). Key words: placenta; volume; parenchyma; non-parenchyma; preeclampsia. DOI: 10.3329/jdmc.v17i2.6587J Dhaka Med Coll. 2008; 17(2) : 78-82


2017 ◽  
Vol 4 (6) ◽  
pp. 1940
Author(s):  
T. Prashanth Reddy ◽  
Ramesh Chittam ◽  
Sravan Kumar T. ◽  
Sindhura K. ◽  
Sanjeev Chetty

Background: NRBCs are physiologically found only in the peripheral blood of the fetus and neonates. Under all other conditions, NRBC is an indicator of pathology, either increase in erythroid activity or damage to the bone marrow has been suggested that the presence of elevated NRBC in the umbilical cord blood is a sign of fetal hypoxia.1-12. Elevated NRBC is a sign of fetal hypoxia in newborns of mothers with preeclampsia even with well controlled hypertension.Methods: The study period is 1 year from November 2015 to October 2016 on Term SGA babies delivered in Navodaya Medical College Hospital and Research Centre. Inclusion criteria all term SGA and healthy term AGA Newborns. Exclusion criteria were mothers with the following condition: maternal diabetes mellitus, hypertension, preeclampsia, chorioamnionitis and babies with the following conditions meconium stained amniotic fluid, congenital anomalies, twin-to-twin transfusion, severe anemia, cyanotic heart disease.Results: The mean gestational age among control and study group was 18.96 and 19.08 respectively. Low APGAR score (≤5) was seen in 3 cases in the study group. No newborn in control group had low APGAR. Out of 50 babies included in this study,24 babies were delivered by LSCS and 26 babies by normal vaginal delivery. the NRBC count was found to be significantly higher in the SGA babies group as compared to the AGA group and this was statistically significant [p,0.005].Conclusions: My study showed that NRBC count was higher in SGA babies than term AGA babies but there was no correlation of NRBC count with the outcome in SGA babies.


Author(s):  
Sunita Garhwal ◽  
Asha Verma ◽  
Mohinee . ◽  
Kavita Choudhary ◽  
Prem Bajiya

Background: Pre-eclampsia, a condition specific to pregnancy, is a leading cause of maternal and perinatal mortality and morbidity. It has been shown in non-pregnant patients that hypertension increases the tensile stress applied on the carotid artery; in essential hypertension this leads to increased carotid arterial intima–media thickness (IMT) and stiffness. Methods: It was a hospital based comparative observational study conducted at department of Obstetrics and Gynecology, SMS Medical College and attached hospitals, Jaipur. The study included two groups consisting of 30 women in each group. The study group was consist of 30 women with singleton pregnancy with gestational period of ³20 weeks with preeclampsia. 30 normotensive women with singleton pregnancy with gestational period of ³20 weeks was the controls. Results:  Mean IMT in study group was higher as compared to control group and the difference was statistically significant (0.45 ± 0.09 mm v/s 0.35 ± 0.09 mm). Carotid artery internal diameter was higher in study group as compared to control group (7.36 ± 0.61 mm v/s 6.73 ± 0.72 mm). The difference was statistically significant. Conclusion: Intima media thickness measurements in women with pre-eclampsia could offer an opportunity to identify a high-risk group of women who might benefit from early screening and preventive measure. These measures would include life style modification such as improving diet and physical activity and increase surveillance of blood pressure, blood glucose and serum lipid, thereby reducing their cardio-vascular related morbidity and mortality in later life. Keywords: Intima media thickness, pre-eclampsia, blood pressure.


2020 ◽  
Author(s):  
Yuan Gao ◽  
Xiaojie Fu ◽  
Mingxing Lei ◽  
Pengbin Yin ◽  
Qingmei Wang ◽  
...  

BACKGROUND Mobile apps are becoming increasingly relevant to health care. Apps have been used to improve symptoms, quality of life, and adherence for oral drugs in patients with cancers, pregnancy, or chronic diseases, and the results were satisfying . OBJECTIVE This study aims to develop an information platform with the help of a mobile app and then evaluate whether information platform-based nursing can improve patient’s drug compliance and reduce the incidence of VTE in patients with hip fractures. METHODS We retrospectively analyzed hip fracture patients performed with traditional prevention and intervention of VTE (control group) between January 2008 and November 2012, and prospectively analyzed hip fracture patients conducted with nursing intervention based on the information platform (study group) between January 2016 and September 2017. The information platform can be divided into medical and nursing care end and the patient’s end. Based on the information platform, we could implement risk assessments, monitoring management and early warnings, preventions and treatments, health educations, follow-up and other aspects of nursing interventions for patients. We compared basic characteristics, outcomes including drug compliance, VTE occurrence, and mean length of hospitalization between the two groups. Besides, a subgroup analysis was performed in the study group according to different drug compliances. RESULTS Regarding baseline data, patients in the study group had more morbidities than those in the control group (P<0.05). The difference of drug compliance between the two groups was statistically significant (P<0.001): 64.7% of the patients in the control group had poor drug compliance and only 6.1% patients had poor drug compliance in the study group. In terms of VTE, 126 patients (10.7%) in the control group had VTE, while only 35 patients (7.1%) in the study group had VTE, and the difference was statistically significant (P=0.024). Moreover, the average length of hospitalization in the study group was also significantly lower than that in the control group (10.4 d vs. 13.7 d, P=0.000). Subgroup analysis of the study group showed that the incidence of VTE in patients with non-compliance, partial compliance, and good compliance was 56.7%, 5.8% and 2.8%, respectively (P=0.000). CONCLUSIONS Poor drug compliance leads to higher VTE occurrence. The information platform-based nursing can effectively improve the compliance of patients with hip fracture and thus significantly reduce the incidence of VTE.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jae Hwa Kim ◽  
Go-Tak Kim ◽  
Siyeoung Yoon ◽  
Hyun Il Lee ◽  
Kyung Rae Ko ◽  
...  

Abstract Background Vitamin B12 (Vit B12) deficiency results in elevated homocysteine levels and interference with collagen cross-linking, which may affect tendon integrity. The purpose of this study was to investigate whether serum Vit B12 levels were correlated with degenerative rotator cuff (RC) tear. Methods Eighty-seven consecutive patients with or without degenerative RC tear were enrolled as study participants. Possible risk factors (age, sex, medical history, bone mineral density, and serum chemistries including glucose, magnesium, calcium, phosphorus, zinc, homocysteine, Vitamin D, Vit B12, homocysteine, and folate) were assessed. Significant variables were selected based on the results of univariate analyses, and a logistic regression model (backward elimination) was constructed to predict the presence of degenerative RC tear. Results In the univariate analysis, the group of patients with degenerative RC tear had a mean concentration of 528.4 pg/mL Vit B12, which was significantly lower than the healthy control group (627.1 pg/mL). Logistic regression analysis using Vit B12 as an independent variable revealed that Vit B12 concentrations were significantly correlated with degenerative RC tear (p = 0.044). However, Vit B12 levels were not associated with tear size. Conclusion Low serum levels of Vit B12 were independently related to degenerative RC tear. Further investigations are warranted to determine if Vit B12 supplementation can decrease the risk of this condition.


Sign in / Sign up

Export Citation Format

Share Document