scholarly journals Correlation of the Laboratory Findings with a Etiology of Patients Presenting with Fever followed by Altered Consciousness in a Teaching Hospital

1970 ◽  
Vol 18 (1) ◽  
pp. 25-29
Author(s):  
Amaresh Chandra Shaha ◽  
Manabendra Nath Nag ◽  
Arpita Deb ◽  
NC Nath
Keyword(s):  
Cerebrospinal Fluid ◽  
Altered Consciousness ◽  
Pyogenic Meningitis ◽  
Tubercular Meningitis ◽  
College Hospital ◽  
Laboratory Findings ◽  
Medical College ◽  
Group 2 ◽  
Medical Wards ◽  
Very High

Consecutive fifty subjects having fever with altered consciousness admitted into medical wards in Rangpur Medical College Hospital, Rangpur were selected to find out the aetiology and its correlation with laboratory findings of the subjects. Subjects having prolonged fever, (more than 21 days) pregnancy, trauma, drug intoxication, cerebrovascular disease and metabolic causes including liver diseases were excluded from the study. Study revealed that majority of the study subjects were below 39 years (76%) of age and most of them were male (80%). Predominant cases were found to be pyogenic meningitis (44%), followed by encephalitis (32%), cerebral malaria (20%) and tubercular meningitis (4%). Neutrophilic leucocytosis, high cerebrospinal fluid protein, very high cell count and low sugar were a common observation in pyogenic meningitis while very high erythrocytic sedimentation rate was the main findings in tubercular meningitis and high lymphocytic count was observed in encephalitis as compared to other. So it is concluded that subjects suffering from fever with altered consciousness are 1. Predominantly male of young age group. 2. pyogenic meningitis is a predominant cause. 3. Cerebrospinal fluid findings were observed to have usual findings in disease of pyogenic meningitis, encephalitis and tubercular meningitis.   doi: 10.3329/taj.v18i1.3300 TAJ 2005; 18(1): 25-29

scholarly journals Glucose status in cerebrospinal fluid (CSF) in different meningitic children in a hospital in Chittagong, Bangladesh

2013 ◽  
Vol 6 (1-2) ◽  
pp. 41-49
Author(s):  
Sharmistha Mitra ◽  
Robiul Hasan Bhuiyan ◽  
Md Arifuzzaman ◽  
Mohammad Sayedul Islam ◽  
Mahmood A Chowdhury ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Glucose Level ◽  
Viral Meningitis ◽  
Pyogenic Meningitis ◽  
Detailed Medical History ◽  
Different Types ◽  
The Brain ◽  
Very High ◽  
Potential Tool ◽  
Glucose Status

Meningitis is referred to as an inflammatory process of the leptomeninges and cerebrospinal fluid (CSF) within the sub-arachnoid space of the brain. We have investigated glucose status in CSF in different types of meningitis together with detailed medical history in children. In addition, we have also carried out the detailed cytological and microbiological examinations. A total of 40 subjects were investigated. We observed that the glucose level was significantly decreased (<20 mg/dl) in 65%, moderately decreased (20-40 mg/dl) in 20% and mildly decreased (40-50mg/dl) in 15% of the patients in our study. Patients with Pyogenic meningitis had tremendously reduced glucose level (9.0 mg/dl) in their CSF whereas in viral meningitis the CSF glucose level is highly variable (10 to 65 mg/dl). Furthermore, 5 (12.5%) patients showed high lymphocyte counts and 34 (85%) patients showed high neutrophil counts. Interestingly, in Pyogenic meningitis, the neutrophil count was very high compared to that in viral meningitis. The present study clearly demonstrates that biochemical parameters such as glucose level in CSF might be a potential tool for detecting meningitis and as well as differentiation of the different types of meningitis. DOI: http://dx.doi.org/10.3329/cujbs.v6i1-2.17080 The Chittagong Univ. J. B. Sci.,Vol. 6(1&2):41-49, 2011

scholarly journals Primary Retroperitoneal Ganglioneuroma: A Retrospective Cohort Study of 32 Patients

2021 ◽  
Vol 8 ◽  
Author(s):  
Jianchun Xiao ◽  
Zixuan Zhao ◽  
Binglu Li ◽  
Taiping Zhang
Keyword(s):  
Growth Pattern ◽  
Clinical Manifestations ◽  
Incomplete Resection ◽  
Radiological Imaging ◽  
College Hospital ◽  
Laboratory Findings ◽  
Female Ratio ◽  
Medical College ◽  
The Mean ◽  
The Masses

Purpose: To investigate the clinical characteristics, diagnosis, differential diagnosis, therapy options, and outcomes of retroperitoneal ganglioneuroma.Methods: In this retrospective study, we collected and analyzed the clinical data of 32 patients diagnosed with retroperitoneal ganglioneuroma and admitted to Peking Union Medical College Hospital from October 2012 to August 2019.Results: Among our 32 cases with retroperitoneal ganglioneuroma, the male-to-female ratio was 1:3 and the mean age was 35. Only 25% of the cases presented with abdominal pain while more than 65% had no specific symptoms. The masses could be found through physical examination in only five patients. Most of the tumors are located near the renal area. They were usually single and displayed an embedded growth pattern with diameters &lt;10 cm, clear borders, and soft texture. For radiological imaging, the majority of tumors demonstrated soft tissue density with mild-to-moderate enhancement on CT imaging and showed hypoecho with moderate blood flow signals in ultrasound. No significantly abnormal laboratory examinations were found in most patients. Of all the 32 patients, 2 chose surveillance after biopsy due to difficulties in operation, while others chose surgical resection. The mean follow-up time was 15.8 months among 26 patients. The tumor remained stable in the surveillance cases. Residual tumors were found in four cases receiving operations with no progress and discomfort. No recurrence was seen in all patients.Conclusions: The retroperitoneal ganglioneuroma is a benign tumor without specific clinical manifestations or significant laboratory findings. Typically, it is shown as low density with a clear border and an embedded growth pattern in radiological imaging. The overall prognosis is good. Surgery is an effective approach with possible severe complications. Incomplete resection or surveillance can be considered for some cases where complete resection is difficult to achieve.

scholarly journals Comparative analysis of cerebrospinal fluid adenosine deaminase levels in infective meningitis of different aetiologies

2017 ◽  
Vol 4 (2) ◽  
pp. 608
Author(s):  
Mohsin Rashid ◽  
Sheikh Mushtaq ◽  
Junaid Manzoor ◽  
Javaid Ahmad Bhat ◽  
Shilakha Chaman ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Diagnostic Accuracy ◽  
Adenosine Deaminase ◽  
Aseptic Meningitis ◽  
Predictive Value ◽  
Cost Effective ◽  
Systemic Lupus Erythematosis ◽  
Pyogenic Meningitis ◽  
Tubercular Meningitis ◽  
High Level

Background: Meningitis can be caused by bacteria, viruses, parasites, and fungi as well as by non-infectious conditions including inflammatory disorders (e.g., systemic lupus erythematosis or Kawasaki disease) and neoplasia (e.g., leukemic meningitis). The objective of this study were to study cerebrospinal fluid (CSF) adenosine deaminase (ADA) levels in infective meningitis of different aetiologies. And to assess the role of cerebrospinal fluids (CSF) adenosine deaminase (ADA) levels in differentiating tubercular from non-tubercular meningitis.Methods: The study was conducted on 70 patients of meningitis at Postgraduate Department of Paediatrics, in G. B. Pant Hospital, an associated hospital of Government Medical College Srinagar. Out of 70 patients included in the study 27 cases were Aseptic Meningitis (AM), 14 cases partially treated pyogenic -meningitis (PTM), 19 cases pyogenic meningitis (PM), and 10 cases were tubercular meningitis (TBM). ADA activity of CSF was quantified by colorimetry.Results: In our study we observed a significant high level of ADA 30.0±3.2U/L (20.0, 54.0) among the tubercular meningitis (TBM) patients and its respective level among Aseptic Meningitis (AM), was 8.1±0.3U/L (4.0, 11.5), partially treated pyo -meningitis (PTM) was 7.6±0.4U/L (5.0, 11.0), pyogenic meningitis (PM) was 11.6±0.5U/L (8.0, 14.5). In total Non-TBM ADA level was 9.1±0.3U/L (4.0, 14.5) units/liter. At cut off of > or equal to 10U/L sensitivity was 100% specificity66.67% positive predictive value33.33% negative predictive value of 100% diagnostic accuracy 71.43%. At a higher cut off of > or equal to 12U/L sensitivity was 100% and specificity increased to 81.67% positive predictive value 47.62% negative predictive value100% diagnostic accuracy was 84.29%.Conclusions: The sensitivity and specificity of CSF ADA activity is markedly high in differentiating TBM from non-TBM. Hence CSF ADA activity may be used as a simple, cost-effective and reliable test for early diagnosis of TBM.

scholarly journals Clinical Profile of Meningitis in Children

2018 ◽  
Vol 28 (1) ◽  
pp. 6-11
Author(s):  
MB Uddin ◽  
M Rahman ◽  
KI Jahan ◽  
S Yeasmin ◽  
F Rahman
Keyword(s):  
Aseptic Meningitis ◽  
Clinical Problem ◽  
Cross Sectional Study ◽  
Suspected Case ◽  
Pyogenic Meningitis ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Meningitis In Children ◽  
Untreated Individuals

Meningitis is an emergency clinical problem in pediatrics. The mortality from meningitis is close to 100% in untreated individuals and can still be up to 40% in children who received appropriate antibiotic therapy in developing countries. A cross sectional study was done to address the common presentation of meningitis among the children. The study was conducted in the Pediatric unit of Rajshahi Medical College Hospital from March 2008 to July 2009. A total of 130 suspected case of meningitis patients were included in the study. Among them 102 were diagnosed as meningitis of 66 children with pyogenic meningitis, 36 children with aseptic meningitis and 28 children without meningitis were taken as non meningitis group. This study showed that all patients (100%) had fever. 97 (95.10%) had symptom of convulsion. Vomiting was present in 62 (60.78%), excessive cry or irritability present in 50(49%) cases. This study expressed that 75 (73.53%) patients had bulged fontanel. Neck rigidity was present in 67 (65.69%). Only 32.35% had kernig’s sign positive and 17.65% present with Brudginsky’s sign positive. The infancy was the most vulnerable age for pyogenic meningitis. H. influenzae were the leading pathogen (24.24%) in infancy followed by S. pneumoniae (21.21%). The result shows that among 66 pyogenic meningitis, 26 (39.39%) were completely cured and 24 (36.37%) were cured with sequelae. Out of 36 aseptic meningitis 27 (75.00%) were completely cure.TAJ 2015; 28(1): 6-11

scholarly journals Clinical Presentation of Dengue in 150 Admitted Cases in Dhaka Medical College Hospital

1970 ◽  
Vol 7 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Md Abul Kalam Azad ◽  
Hanif Mohammad ◽  
Md Billal Alam ◽  
Anup Kumar Saha ◽  
Tofayel Ahmed
Keyword(s):  
Dengue Fever ◽  
Prospective Observational Study ◽  
Health Hazard ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
Medical College Hospital ◽  
College Hospital ◽  
Medical College ◽  
Group 3 ◽  
Group 2

Dengue fever was not recognized as a major public health hazard in Bangladesh before 1999 outbreak, so there was little evidence and awareness in this regard. A prospective observational study was carried out to determine the risk group of patients suffering from dengue syndrome; clinical parameters of the subjects for hospitalization and the pattern of presentation of dengue fever in hospital care in different medicine units of Dhaka Medical College hospital from July 2000 to March 2001. Total 150 cases were selected randomly and diagnosed clinically as dengue, and were classified into 3 groups, i.e. 18 cases of classical dengue fever, 127 cases of dengue hemorrhagic fever (DHF-I and DHF-II) and 5 cases of dengue shock syndrome (DSS), and were discharged uneventfully. Among them 125(83.3%) were male and 25(16.7%) were female. Mean ages of the subjects were 26.75 ±3.69, 27.59 ± 1.18 and 10.67 ± 2.33 years in respective groups. Mean temperature was 103.45±0.28, 103.08±0.13, and 104.00±1.00 °F with mean duration was 5.50±0.51 days, 6.12±0.2 days, and 5.00±1.15 in respective groups. Majority had profound weakness, headache, myalgia, anorexia, nausea, and vomiting. Diarrhoea, abdominal pain, organomegaly, ascites, and pleural effusion were frequent complaints in group-3 patients, whereas infrequent complaints in other groups. Haemorrhagic manifestations were common in group 2 and 3 patients, melaena being the most common manifestations.   DOI = 10.3329/jom.v7i1.1355 J MEDICINE 2006; 7: 3-9

scholarly journals Laboratory Profiles of Pleural effusion Collected from Children: Experience at a Tertiary Care Hospital in Bangladesh

2013 ◽  
Vol 5 (1) ◽  
pp. 26-27
Author(s):  
Mahmudul Hasan ◽  
Md Rafiqul Islam ◽  
Abdul Matin ◽  
Ranjit Ranjan Roy ◽  
Md Abdullah Yusuf ◽  
...  
Keyword(s):  
Pleural Effusion ◽  
Pleural Fluid ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
College Hospital ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Medical College ◽  
Almost All

Background: Pleural effusion occurs in many reasons. Laboratory tests are necessary to find out the causes. Objective: This study was an attempt to know the laboratory findings of pleural effusion. Methodology: This cross-sectional study of thirty (30) admitted cases with pleural effusion confirmed by chest radiography and aspiration of pleural fluid from one (1) year to twelve (12) years age of either sex were collected purposively. This study was carried out from July 2009 to February 2010 in the Department of Pediatrics at Rajshahi Medical College Hospital. All information were recorded in pre tested semi structured questionnaire. Results: Color of pleural fluid was straw in 56.7%, clear in 30.0%, blood stained in 13.3%. In this study, lymphocyte predominance among 56.7% cases, acid fast bacilli in 3.3% cases and raised protein of more than 3gm/dl and sugar less then 60mg/dl in 93.3% cases in pleural fluid. Conclusion: In almost all cases protein is raised and sugar is less in pleural fluid. DOI: http://dx.doi.org/10.3329/jssmc.v5i1.16201 J Shaheed Suhrawardy Med Coll, 2013;5(1):26-27

Clinico-Pathological Profiles and Outcomes of Acute Viral Encephalitis in Children

2020 ◽  
Vol 7 (1) ◽  
pp. 8-11
Author(s):  
Sarjina Anwar ◽  
Nazma Begum ◽  
Soofia Khatoon ◽  
Rafia Rashid
Keyword(s):  
Cerebrospinal Fluid ◽  
Herpes Simplex ◽  
Medical College Hospital ◽  
College Hospital ◽  
Altered Level ◽  
Medical College ◽  
Cranial Nerve Palsies ◽  
Level Of Consciousness ◽  
Normal Colour ◽  
Simplex Virus

Background: Encephalitis is an acute inflammatory process that affects brain tissue and is almost always accompanied by inflammation of the adjacent meninges. The disease is most commonly caused by viral infection. Objective: The purpose of the present study was to determine the clinical and cerebrospinal fluid profile of childhood encephalitis and to document Herpes simplex antibody status in cerebrospinal fluid. Methodology: This descriptive analytical study was conducted in Department of Paediatrics of Shaheed Suhrawardy Medical College Hospital and Dhaka Medical College Hospital from May 2011 to October 2011. A total of 30 children of encephalitis were included in this study. Cerebrospinal fluid (CSF) routine and Herpes Simplex virus (HSV) antibody in CSF were done to all patient. Result: Fever and convulsion was found in 29(96.7%) and 28(93.3%) cases respectively in studied patients. Altered level of consciousness was present in 29(96.7%) cases. Fever, convulsion and altered level of consciousness was statistically significant (p<0.05). Glasgow coma scale (GCS) between 4 to 8 was found in 27 (90%) cases. Signs of meningeal irritation and cranial nerve palsies was found in 9 (30%) and 4 (13.3%) cases respectively. Exaggerated deep reflex was found in 23 (76.6%) cases whereas diminished deep reflex was found in 7 (23.3 %) cases. In cytological study of CSF, lymphocyte was found in 28 (93.3%) patients. Raised protein was found in 16(53.3%) and normal in 14 (46.7%) cases. Among the 30 studied cases 9(30%) cases were IgG positive for HSV, 21 (70.0%) were IgG negative and none were IgM positive. Conclusion: Fever, convulsion, altered sensorium and low GCS were common clinical profile in children. Normal colour, increase lymphocyte count, normal sugar level were significant findings in CSF study. Bangladesh Journal of Infectious Diseases 2020;7(1):8-11

scholarly journals CHOICE OF CONTRACEPTION

2015 ◽  
Vol 22 (04) ◽  
pp. 380-384
Author(s):  
Malahat Mansoor
Keyword(s):  
P Value ◽  
Central Park ◽  
Medical College ◽  
Study Results ◽  
General Expectation ◽  
Group 2 ◽  
Women's Role ◽  
Relationship Of ◽  
The Relationship ◽  
Very High

Objective: To observe the relationship of parity with awareness &liberty of useof contraception among married women. Study design: Descriptive study. Period: 1.02.2014to 30.09.2014. Settings: Department of Obstetrics & Gynecology, Bhatti International Hospital,Affiliated Central Park Medical College, LHR. Methods: All Primipara & multipara women deliveringat Bhatti Hospital were included. The women opting for permanentmethod (Tubal Ligation) wereexcluded. A total of 100 women participated in the study. Results: P1=44,P2-7=56,& out oftotal 100 women only 50 (50%) had simple awareness about contraception. Only 27% (all ofgroup 2 i.e P2-7) had used some form of contraception. Among Group 2, 30% used Barrier(male condoms),7% withdrawal, IUCD 5%, Pills 3%,Injections1%. Multipara were more awarethan primiparas with p value 0.043(significant).Both groups were equally dependent on theirhusbands&/or in laws directly or indirectly about their decision &choice of contraception withp value 0.49 (not significant).The decision of contraceptives use depended on couples 36%,Only Husbands 34%,only women 27%& in laws 3%.The Group 2 had a low tendency to usecontraception despite a general expectation with p value 0.36 (not significant) indicating thatthe probability of use in Group 2 was not very high. Conclusions: Both men & women need tobe aware of the benefits of contraception & women’s role in contraception decision making isstill low in Pakistan

scholarly journals Outcome of tetanus patients admitted in Rangpur Medical College Hospital

2016 ◽  
Vol 7 (2) ◽  
pp. 77
Author(s):  
Md. Ismail Hossain ◽  
Mainuddinin Ahmed ◽  
Devendra Nath Sarkar ◽  
A.K.M Shaheduzzaman ◽  
Mirza Sumaiya Tanzina ◽  
...  
Keyword(s):  
Incubation Period ◽  
Vegetative State ◽  
Persistent Vegetative State ◽  
Case Fatality ◽  
Medical College Hospital ◽  
College Hospital ◽  
Medical College ◽  
Male Patients ◽  
Public Health Hazards ◽  
Medical Wards

<p><strong>Background:</strong> Tetanus remains one of the major public health hazards of the developing world. Mortality is much lower in the developed world because of the availability of facilities, unlike in most developing countries' Objectives: This study was aimed to determine the outcome of tetanus patients admitted in infectious disease unit of Rangpur Medical College Hospital. <strong>Methods:</strong> A total of 91 cases of tetanus patients were seen in the 18 month period with a mean of 5 cases per month; they are diagnosed and managed for tetanus in the medical wards from January 2011 to June 2012. The data were retrieved from their case records and analyzed. <strong>Results:</strong> There were thirty one deaths, accounting for an overall mortality of 34.16o.Total fifty six patients were cured among which sixteen (17.67%) were cured with complication and four (4.4%) patient were absconded. Mortality was high 45.84% (11 patients out of 24) ≥40 years age, whereas low 29.85 (20 patient out of 87) in &lt;40 yea15 age (45.84% vs 29.85%). Mortality rate was also higher among female than male patients (34.66% vs 33.85%). Farmers experienced more death than non-farmer (4l.l8% vs 29-82%, P&lt;0.05). Mortality was higher in patients who had not received any medical treatment for their wound than in patients who had received it for their wound (52.78% vs 21.81%, p&lt;0.05). Patients with short incubation period of less than one week had higher mortality in comparison with those who had incubation period more than one week (53.33% vs 23.25%, P&lt;0'05). Of the 91 patients, fifty six (64.34%) were alive, though four remained in a persistent vegetative state due to tetanus toxin-induced brain damage and another two required a below knee amputation of the left leg. Hence, 40 were discharged well and 16 were discharged with permanent disabilities. <strong>Conclusion:</strong> The case fatality rate of tetanus has remained consistently high in the medical college. Factors that were significantly associated with high mortality included older age, and incubation period of less than 7 days. It is recommended that preventive immunization against tetanus be given to all Bangladeshis with secondary vaccination at adulthood.</p>

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