scholarly journals Use of Bauhinia forficata Link infusion in the treatment of diabetes mellitus

2020 ◽  
Vol 9 (10) ◽  
pp. e3159108574
Author(s):  
Daniela da Costa de Oliveira ◽  
Samuel Vitor Assis Machado de Lima ◽  
João Paulo Lima de Oliveira
Keyword(s):  
Diabetes Mellitus ◽  
Scientific Evidence ◽  
Boolean Operator ◽  
Hypoglycemic Agent ◽  
The World ◽  
Clinical Case Studies ◽  
Treatment Of Diabetes ◽  
The Subject ◽  
Bauhinia Forficata ◽  
Positive Results

Diabetes mellitus is a chronic disease that affects millions of people around the world. One of the medicinal plants used by the Brazilian population in the treatment of diabetes mellitus is Bauhinia forficata Link. The objective of this work was to conduct a review of clinical case studies in order to analyze the hypoglycemic effect of B. forficata infusion in diabetic and pre-diabetic individuals. A direct search for articles of clinical cases was carried out in the databases LILACS, PubMed, SciELO, and Scopus. Were searched works in Spanish, English and Portuguese, published in the last 10 years and that only used the infusion of leaves of the plant species in the treatment of mens and womens, over the age of 18, with pre-diabetes or diabetes mellitus. Were used the keywords "Bauhinia forficata" and "diabetes", and the boolean operator “AND”. Five studies were found, of which three of them presented positive results in relation to the use of B. forficata infusion as an effective hypoglycemic agent in diabetic and pre-diabetic individuals, while two studies did not present positive results. It was concluded that the infusion of B. forficata is able to assist in the treatment of diabetes mellitus, despite the need for more scientific evidence on the subject.

Association and treatment of diabetes in patients affected by Covid-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1198-1201
Author(s):  
Syed Yasir Afaque
Keyword(s):  
Diabetes Mellitus ◽  
Prognostic Value ◽  
Heart Diseases ◽  
The Novel ◽  
The World ◽  
Treatment Of Diabetes ◽  
Coronavirus Infection ◽  
Composite Outcomes ◽  
Novel Coronavirus ◽  
The Impact

In December 2019, a unique coronavirus infection, SARS-CoV-2, was first identified in the province of Wuhan in China. Since then, it spread rapidly all over the world and has been responsible for a large number of morbidity and mortality among humans. According to a latest study, Diabetes mellitus, heart diseases, Hypertension etc. are being considered important risk factors for the development of this infection and is also associated with unfavorable outcomes in these patients. There is little evidence concerning the trail back of these patients possibly because of a small number of participants and people who experienced primary composite outcomes (such as admission in the ICU, usage of machine-driven ventilation or even fatality of these patients). Until now, there are no academic findings that have proven independent prognostic value of diabetes on death in the novel Coronavirus patients. However, there are several conjectures linking Diabetes with the impact as well as progression of COVID-19 in these patients. The aim of this review is to acknowledge about the association amongst Diabetes and the novel Coronavirus and the result of the infection in such patients.

scholarly journals TRADITIONAL MEDICINAL SYSTEMS FOR TREATMENT OF DIABETES MELLITUS: A REVIEW

2018 ◽  
Vol 10 (5) ◽  
pp. 7
Author(s):  
Dimple . ◽  
Ashwani Kumar ◽  
Vikas Kumar ◽  
Vidisha Tomer
Keyword(s):  
Diabetes Mellitus ◽  
Functional Foods ◽  
Medical Science ◽  
Herbal Medicines ◽  
Diabetes Treatment ◽  
Active Components ◽  
The World ◽  
Increasing Trend ◽  
Current Scenario ◽  
Treatment Of Diabetes

Diabetes mellitus (DM) is a chronic disease which has clinched the world. More than 300 million people of the world are suffering from this disease and the number is still increasing at a rapid rate as modern medical science has no permanent solution for the disease. Current scenario of the nutraceuticals has increased patient’s faith on the traditional medicinal system and world nutraceutical industry is estimated to reach $285.0 billion by 2021. The increasing trend of nutraceuticals in diabetes treatment makes it important to collect the traditional knowledge of medicines under one heading as it can help researchers to formulate new functional foods and nutraceuticals which can either lower down the risk or cure DM. In addition, the discussion of market available food products, their active components and possible health benefits can help the patients to understand the herbal medicines in a better way.

scholarly journals The internet racing ahead of the scientific evidence: the case of "liberation treatment" for multiple sclerosis

2011 ◽  
Vol 69 (3) ◽  
pp. 525-527 ◽  
Author(s):  
Yára Dadalti Fragoso
Keyword(s):  
Multiple Sclerosis ◽  
Neurological Disease ◽  
Venous Insufficiency ◽  
Scientific Evidence ◽  
The Internet ◽  
Evidence Based ◽  
The World ◽  
Internet Discussion ◽  
The Central Nervous System ◽  
The Subject

Multiple sclerosis (MS) is a chronic neurological disease that typically affects young adults. A recent publication suggested that MS might originate from insufficient blood drainage in certain areas of the central nervous system. The condition was named chronic cerebrospinal venous insufficiency (CCSVI). Other papers have not confirmed these findings and, therefore, the matter remains controversial. Nineteen months after the original publication on CCSVI and MS, another 22 papers have been published addressing the matter. No clinical trials have been carried out on the subject and there is no evidence-based indication to perform surgical vascular procedures in MS patients. However, over the same nineteen-month period, the internet discussion on the subject of CCSVI and MS has led to countless websites advertising treatment using vascular surgery for patients with MS all over the world. The treatment based on the CCSVI theory has appealingly been called "liberation treatment", thus making it difficult to explain to patients why a treatment that has been highly praised (on the internet) cannot be recommended based on partial medical results that await confirmation.

Letter to the Editor

2002 ◽  
Vol 17 (4) ◽  
pp. 192-192
Author(s):  
Ian Winspur
Keyword(s):  
Subject Matter ◽  
Performing Arts ◽  
Scientific Evidence ◽  
Performing Arts Medicine ◽  
Letter To The Editor ◽  
The World ◽  
The Subject ◽  
The Law

I enjoyed Alice Brandfonbrener’s editorial “But I Didn’t Ask to Be a Lawyer” in the June 2002 issue of MPPA [MPPA 2002;17(2):57]. I understand and sympathize with her. Many physicians who, like her, are involved in these cases for altruistic reasons rather than pure commercial—-and I believe that this is more common in the world of performing arts medicine—-must find themselves in the same predicament. However, in the words of an eminent English lawyer, who qualified and practiced as a gynecologist before turning to the law, when considering medical and scientific evidence (or in many cases, including performers, non-scientific evidence!): “However scientific the subject matter of the claim and however recondite the evidence and the argument, the legal definitions must apply in a Court of Law; the problem for the lawyer is in making the scientist understand a totally different concept of proof required by the court.” Therefore physicians involved, whether altruistic or not, must understand the basis of these claims.

scholarly journals Turismo e voluntariado: a busca pela compreensão do volunturismo

2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Pablo Braga de Souza ◽  
Antônia Maria Nascimento Barcelos ◽  
Suellen Alice Lamas
Keyword(s):  
Early Stage ◽  
Economic Potential ◽  
Volunteer Tourism ◽  
The Public ◽  
Mass Tourism ◽  
Negative Results ◽  
De Se ◽  
The World ◽  
The Subject ◽  
Positive Results

Ao longo do tempo, o turismo tem se destacado como uma importante atividade econômica no mundo, gerando serviços, produtos, emprego e renda. Entretanto, tão importante quanto o seu potencial econômico, é o seu potencial social, capaz de transformar localidades que apresentam desequilíbrios e limitações, o que vem sendo proposto pelo turismo voluntário também conhecido como volunturismo. Embora seja muito praticada no exterior, essa modalidade, está em estágio inicial no país, o que traz à tona dúvidas e questionamentos em relação ao tema e a necessidade de estudá-lo a fim de que se possa compreendê-lo em sua totalidade. Deste modo, faz-se a reflexão: O que é turismo voluntário? Qual o perfil do público que o pratica? Quais as diferenças entre turismo voluntário e turismo solidário? Quais os impactos nas comunidades visitadas? A partir desses questionamentos, o presente trabalho visa discorrer sobre o turismo voluntário apresentando suas interfaces conceituais, problemáticas e perfil dos praticantes, de modo a contribuir com o esclarecimento e debate teórico sobre o tema. Assim, vê-se a importância de estudos em relação ao turismo voluntário para que, a partir de sua compreensão, os resultados positivos possam ser maximizados e os negativos minimizados. Baseando-se em seu caráter de agente transformador social, pode-se inferir que o turismo voluntário é mais uma forma de se fazer turismo, contrária ao turismo de massas, do que um segmento propriamente dito. Tourism and volunteering: the search for understanding of the voluntourism ABSTRACT Over time, the tourism has distinguished itself as an important economic activity in the world, generating services, products, employment and income. However, as important as its economic potential, it is its social potential capable of transforming localities that show unbalances and limitations, what has been proposed by the volunteer tourism also known as voluntourism. Although it has been practiced abroad, this type of tourism is in an early stage in the country, which propitiates doubts and questions concerning the theme and the necessity to study it in order to understand it in its entirety. Thus, the reflection is done: What is volunteer tourism? What is the public profile that practices it? What are the differences between volunteer tourism and solidary tourism? What are the impacts on the communities visited? Based on these questions, the article aims to discuss about volunteer tourism showing its conceptual interfaces, problematic and the profile of the participants in order to contribute to the elucidation and the theoretical debate on the subject. Therefore, one sees the importance of the studies concerning volunteer tourism so that, from its understanding, positive results can be maximized and negative results can be minimized. Based on its character of a social transforming agent, one can infer that the volunteer tourism is more a way of doing tourism, contrary to mass tourism, than a segment itself. KEYWORDS: Volunteering; Tourism; Knowledge; Voluntourism.

scholarly journals The exchange of vitamins in diabetes

2000 ◽  
Vol 46 (5) ◽  
pp. 39-45
Author(s):  
V. M. Kodentsova ◽  
O. A. Vrzhesinskaya ◽  
V. B. Spirichev
Keyword(s):  
Diabetes Mellitus ◽  
Protective Effect ◽  
Experimental Diabetes ◽  
Complex Treatment ◽  
Experimental Diabetes Mellitus ◽  
Chemical Agents ◽  
Treatment Of Diabetes ◽  
The Subject ◽  
Methodological Approaches ◽  
Therapeutic Doses

The problem of vitamins and diabetes has been the subject of a large number of experimental and clinical studies. They consider such aspects as the effect of insufficiency of certain vitamins on the induction (by alloxan or streptozotocin) of experimental diabetes mellitus; study of the protective effect of vitamins from these chemical agents; study of the actual provision of vitamins for people with diabetes; identification of the features of the metabolism of vitamins in this disease; the use of vitamins in prophylactic or therapeutic doses in the complex treatment of diabetes mellitus [20, 26, 51]. Despite the abundance of such studies, there is still no consensus on whether the exchange of B vitamins changes in diabetes mellitus. This is determined by a number of reasons, due to both the features of methodological approaches and the use of nonspecific analytical methods, as well as the application of the criteria for assessing vitamin supply, adopted for healthy people.

Medicinal plants in the supplementary treatment of diabetes mellitus

2011 ◽  
Vol 5 (7) ◽  
pp. 1738
Author(s):  
Manuelle Arias Piriz ◽  
Marcos Klering Mesquita ◽  
Teila Ceolin ◽  
Caroline Vasconcellos Lopes ◽  
Rita Maria Heck
Keyword(s):  
Diabetes Mellitus ◽  
Medicinal Plants ◽  
Rio Grande ◽  
Ethics Committee ◽  
Rio Grande Do Sul ◽  
Treatment Of Diabetes ◽  
Supplementary Treatment ◽  
Positive Results ◽  
De Medicina ◽  
Structured Questionnaire

ABSTRACTObjective: to list the main medicinal plants used by ecological farmers from southern Rio Grande do Sul in the supplementary treatment of diabetes mellitus. Method: it was performed a study with qualitative approach of  exploratory and descriptive kind. The study subjects were farmers who sell their products at the ecological fair of Pelotas. Data were collected using semi-structured questionnaire. The interviews were recorded with consent of farmers and the plants were georeferenced and photographed for taxonomic  identification. The project was approved by the Ethics Committee of the Faculty of Medicine at 072/2007 opinion. Results: ten plants were mentioned in the treatment of diabetes mellitus. According to the literature, six of them had positive results in animals or humans as hypoglycemiants, and the other plants are indicated to treat various other symptoms. Conclusion: medicinal plants can act as an adjuvant of the medicamentous therapy in reducing glicemy of the disease carriers, taking into account the legal and safe precepts for using and importance of nurses in advising on the correct use of these therapies. Descriptors: phytotherapy; rural health; diabetes mellitus; nursing.RESUMOObjetivo: listar as principais plantas medicinais utilizadas por agricultores ecológicos do sul do Rio Grande do Sul no tratamento complementar do diabetes mellitus. Método: foi realizado um estudo de abordagem qualitativa do tipo exploratório e descritivo. Os sujeitos foram agricultores que comercializam seus produtos na feira ecológica de Pelotas. Os dados foram coletados utilizando questionário semi-estruturado. As entrevistas foram gravadas com consentimento dos agricultores e as plantas georreferenciadas e fotografadas para identificação taxonômica. O projeto foi aprovado pelo Comitê de Ética da Faculdade de Medicina por meio do parecer 072/2007. Resultados: foram citadas dez plantas utilizadas no tratamento de diabetes mellitus. De acordo com a literatura, seis delas obtiveram resultados positivos em animais ou humanos como hipoglicemiantes, as demais são indicadas para tratar outros diversos sintomas. Conclusão: as plantas medicinais podem atuar como adjuvantes da terapia medicamentosa na redução da glicemia de portadores da doença, levando-se em conta os preceitos legais e seguros da utilização e a importância dos enfermeiros no aconselhamento sobre o correto uso destas terapias. Descritores: fitoterapia; saúde da população rural; diabetes mellitus; enfermagem. RESUMENObjetivo: elaborar una lista de las principales plantas medicinales utilizadas por los agricultores ecológicos del sur de Río Grande do Sul en el tratamiento suplementario de la diabetes mellitus. Método: se realizó un estudio com um abordaje cualitativo de naturaleza exploratoria y descriptiva. Los sujetos de estudio fueron los agricultores que venden sus productos en la feria ecológica de Pelotas. Los datos fueron recolectados a través de cuestionario semi-estructurado. Las entrevistas fueron grabadas con el consentimiento de los agricultores y las plantas georeferenciados y fotografiados para su identificación taxonómica. El proyecto fue aprobado por el Comité de Ética de la Facultad de Medicina de la opinión 072/2007. Resultados: diez plantas fueron mencionadas en el tratamiento de la diabetes mellitus. De acuerdo con la literatura, seis de ellos tuvieron resultados positivos en animales o seres humanos como agentes hipoglucemiantes, los otros están indicados para el tratamiento de varios otros síntomas. Conclusión: las plantas medicinales pueden actuar como adyuvante a la terapia medicamentosa en la reducción de la glicemia en los portadores de la enfermedad, teniendo en cuenta los preceptos legales y seguros de la iutilización y la importancia de las enfermeras en el aconsejamiento sobre el correcto uso de estas terapias. Descriptores: fitoterapia; salud rural; diabetes mellitus; enfermería.

scholarly journals The Efficacy of Optimism: Benefit Finding in the Treatment of Diabetes in Iranian Patients

ISRN Nursing ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Hossein Karimi Moonaghi ◽  
Hossein Namdar Areshtanab ◽  
Leila Jouybari
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Disease ◽  
Middle Eastern ◽  
Benefit Finding ◽  
The World ◽  
Treatment Of Diabetes ◽  
Lack Of Exercise ◽  
The Many ◽  
Iranian Patients

The incidence of diabetes mellitus is on the rise around the world. Middle Eastern countries will be facing a vast increase in the number of diabetes mellitus cases by 2030. Diagnosis of a chronic disease such as diabetes mellitus can be a shocking and life-altering event. Conversely, a diagnosis of a chronic illness can also offer the patient opportunities to change unhealthy behaviors such as poor diet, smoking, and lack of exercise, making them healthier than before their diagnosis. This is referred to as “benefit finding”. This study reveals the many benefit findings of Iranian patients who have been diagnosed with diabetes mellitus and illustrates how benefit finding can be an integral part of long-term patient care.

scholarly journals Network pharmacology-based assessment to elucidate the molecular mechanism of anti-diabetic action of Tinospora cordifolia

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Pukar Khanal ◽  
B. M. Patil ◽  
Bijendra K. Mandar ◽  
Yadu Nandan Dey ◽  
Taaza Duyu
Keyword(s):  
Diabetes Mellitus ◽  
Molecular Mechanism ◽  
Structural Information ◽  
Scientific Evidence ◽  
Docking Study ◽  
Tinospora Cordifolia ◽  
Network Pharmacology ◽  
Receptor Interaction ◽  
Protein Molecules ◽  
Treatment Of Diabetes

Abstract Background Tinospora cordifolia is used traditionally for the treatment of diabetes and is used in various formulations. Scientific evidence is also available for its anti-diabetic potency under various animal models. However, the probable molecular mechanism of Tinospora cordifolia in the treatment of diabetes has not been illuminated yet. Hence, the present study dealt to elucidate the probable molecular mechanism of anti-diabetic effect of Tinospora cordifolia using network pharmacology approach. Methods The structural information of bioactive phytoconstituents was retrieved from different open source databases. Compounds were then predicted for their hits with the probable targets involved in the diabetes mellitus. Phytoconstituents were also predicted for their druglikeness score, probable side effects, and ADMET profile. The modulated protein pathways were identified by using the Kyoto Encyclopedia of Genes and Genomes pathway analysis. The interaction between the compounds, proteins, and pathways was interpreted based on the edge count. The docking study was performed using Autodock4.0. Results Nine phytoconstituents from Tinospora cordifolia were identified to modulate the pathogenic protein molecules involved in diabetes mellitus. Among them, tembetarine scored highest druglikeness hit and had the maximum interaction with proteins involved in diabetes. Further, neuroactive ligand-receptor interaction was predicted as majorly modulated pathway. Conclusion The current study identified an important antidiabetic constituent, tembetarine which modulated the majority of diabetic proteins majorly modulating neuroactive ligand-receptor interaction.

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