scholarly journals The internet racing ahead of the scientific evidence: the case of "liberation treatment" for multiple sclerosis

2011 ◽  
Vol 69 (3) ◽  
pp. 525-527 ◽  
Author(s):  
Yára Dadalti Fragoso

Multiple sclerosis (MS) is a chronic neurological disease that typically affects young adults. A recent publication suggested that MS might originate from insufficient blood drainage in certain areas of the central nervous system. The condition was named chronic cerebrospinal venous insufficiency (CCSVI). Other papers have not confirmed these findings and, therefore, the matter remains controversial. Nineteen months after the original publication on CCSVI and MS, another 22 papers have been published addressing the matter. No clinical trials have been carried out on the subject and there is no evidence-based indication to perform surgical vascular procedures in MS patients. However, over the same nineteen-month period, the internet discussion on the subject of CCSVI and MS has led to countless websites advertising treatment using vascular surgery for patients with MS all over the world. The treatment based on the CCSVI theory has appealingly been called "liberation treatment", thus making it difficult to explain to patients why a treatment that has been highly praised (on the internet) cannot be recommended based on partial medical results that await confirmation.

2012 ◽  
Vol 27 (1_suppl) ◽  
pp. 2-9 ◽  
Author(s):  
P Gloviczki ◽  
M L Gloviczki

Recently published evidence-based guidelines of the Society for Vascular Surgery (SVS) and the American Venous Forum (AVF) include recommendations for evaluation, classification, outcome assessment and therapy of patients with varicose veins and more advanced chronic venous insufficiency (CVI). The need for such guidelines has been evident since imaging techniques and minimally invasive technologies have progressed by leaps and bounds and radiofrequency ablation, laser and sclerotherapy have largely replaced classical open surgery of saphenous stripping. This report reviews the most important guidelines recommended by the SVS/AVF Venous Guideline Committee. It is obvious, however, that some of the technology that is recommended in North America is either not available or not affordable in some parts of the world for patients with varicose veins and CVI. The readers are urged therefore to also consult the guidelines of their national societies, recent publications of the National Institute for Clinical Excellence and the Venous Forum of the Royal Society of Medicine. Venous specialists should also keep in mind that scientific evidence should always be combined with the physician's clinical experience and the patient's preference when the best treatment is selected for an individual patient.


Author(s):  
Blánaid Daly ◽  
Paul Batchelor ◽  
Elizabeth Treasure ◽  
Richard Watt

Public health is a key concern of modern dental practitioners as they continue to play a vital role in the health of populations across the world. The second edition of Essential Dental Public Health identifies the links between clinical practice and public health with a strong emphasis on evidence-based medicine. Fully revised and updated for a second edition, this textbook is split into four parts covering all the need-to-know aspects of the subject: the principles of dental public health, oral epidemiology, prevention and oral health promotion, and the governance and organization of health services. Essential Dental Public Health is an ideal introduction to the field for dentistry undergraduates, as well as being a helpful reference for postgraduates and practitioners.


2021 ◽  
Vol 84 (2) ◽  
pp. 71-84
Author(s):  
Mohsen Ali Alhomoud ◽  
Abdul Sattar Khan ◽  
Iftetah Alhomoud

<b><i>Background:</i></b> Multiple sclerosis (MS) is an inflammatory demyelinating chronic neurological disease that affects the central nervous system of young adults and their quality of life. Several studies have investigated the effects of pregnancy and breastfeeding on MS. However, the evidence regarding the influence of pregnancy and breastfeeding on MS is still accumulating. This review aimed to summarize the current evidence regarding the effects of pregnancy and breastfeeding on MS. <b><i>Summary:</i></b> A systematic electronic literature search of the PubMed and Embase databases was conducted to determine relevant published articles. The eligible studies were summarized and evaluated in tables. <b><i>Key Messages:</i></b> The majority of the studies indicated that pregnancy appears to lower the rate of MS relapses, particularly in the third trimester. The evidence regarding the effect of breastfeeding on MS remains inconsistent. Despite reports of negative obstetric outcomes in some pregnant women with MS, pregnancies in women with MS should not be categorized as high-risk pregnancies.


2008 ◽  
Vol 8 ◽  
pp. 802-810 ◽  
Author(s):  
Daniel T. L. Shek

In charitable foundations throughout the world, different approaches are used to allocate funding. As many projects with good will (i.e., enthusiasm-based charity) actually fail to help those who really need it, it is argued that the evidence-based approach (i.e., charity guided by scientific evidence) represents the best strategy to support projects that can really help the needy. Using this approach, scientific research findings are systematically used to (1) understand the nature of the problem and/or social needs, (2) design appropriate intervention programs based on the best available evidence, and (3) systematically evaluate the outcomes of the developed program. Using the Project P.A.T.H.S. funded by the Hong Kong Jockey Club Charities Trust as an example, the characteristics underlying this approach are outlined. The systematic use of scientific evidence in the Project P.A.T.H.S. is exemplary in different Chinese societies. This project provides much insight for charitable foundations and funding bodies locally and globally.


2002 ◽  
Vol 17 (4) ◽  
pp. 192-192
Author(s):  
Ian Winspur

I enjoyed Alice Brandfonbrener’s editorial “But I Didn’t Ask to Be a Lawyer” in the June 2002 issue of MPPA [MPPA 2002;17(2):57]. I understand and sympathize with her. Many physicians who, like her, are involved in these cases for altruistic reasons rather than pure commercial—-and I believe that this is more common in the world of performing arts medicine—-must find themselves in the same predicament. However, in the words of an eminent English lawyer, who qualified and practiced as a gynecologist before turning to the law, when considering medical and scientific evidence (or in many cases, including performers, non-scientific evidence!): “However scientific the subject matter of the claim and however recondite the evidence and the argument, the legal definitions must apply in a Court of Law; the problem for the lawyer is in making the scientist understand a totally different concept of proof required by the court.” Therefore physicians involved, whether altruistic or not, must understand the basis of these claims.


2018 ◽  
Vol 41 (2) ◽  
pp. 100-107
Author(s):  
Małgorzata Dankowska-Kosman ◽  
Iwona Staszkiewicz-Grabarczyk

The subject of considerations are social media in the experience of children aged 8. The methodology selected was the method of focus groups. Focus participants were recruited from forty thirdgrade students from two selected primary schools. The results of the research presented in the text indicate a great interest on the part of the youngest generation in social networking sites. At the same time, they signal that children, despite the systematic use of these portals, are aware of the dangers resulting from applying these tools. Keeping watch of the education of their children, parents very often do not permit their offspring to use online resources unconsciously. Students recognize the risk of making inappropriate acquaintances, the consequences of self-presentation on the Internet, while being curious about the world of young citizens who will join active recipients of social networking sites in the near future.


Author(s):  
Enrique Herrera-Acosta ◽  
Gustavo Guillermo Garriga Martina ◽  
Jorge Alonso Suárez-Pérez ◽  
Eliseo Alejandro Martínez-García ◽  
Enrique Herrera-Ceballos

Multiple sclerosis is an autoimmune demyelinating disorder of the central nervous system that shares similar immunopathogenic mechanisms with chronic plaque psoriasis, such as the overexpression of the Th17 pathway. We report the case of a patient with multiple sclerosis and severe chronic plaque psoriasis successfully treated with ixekizumab (anti IL-17A and IL-17A/F monoclonal antibody). The treatment achieved a complete skin clearance (PASI 100 response) with no adverse events or evidence of progression of the neurological disease. Keywords: Psoriasis; Ixekizumab; Multiple sclerosis


2021 ◽  
Vol 24 ◽  
pp. 11-32
Author(s):  
Iker Samper Ayape

Tras los acontecimientos bélicos que asolaron el mundo durante el siglo XX, en concreto, a partid de 1980, aumento el interés y el acercamiento teórico sobre el pasado y la memoria. Partiendo de ello, la cuestión a tratar en el presente trabajo es: qué características tiene nuestro presente y cómo esto determina algunas formas de acceso al pasado. Para luego preguntarnos sobre la relación que se establece con los memoriales, es decir, en qué medida el contexto o condiciones del sujeto mediatizan su relación con la memoria. Dado que la reflexión acerca de la memoria puede estar condicionada por las características propias de nuestro contexto: aceleración social. El acercamiento que puede tener un sujeto perteneciente a las generaciones más alejadas de lo acontecido en el siglo XX difiere mucho de la relación que pueden tener aquellos que vivieron el suceso o las consecuencias de una forma más inmediata. Por ello, debemos preguntarnos: ¿Hemos -sobre todo las generaciones más jóvenes- volcado la memoria y el conocimiento en objetos externos a los que recurrir y de esa manera no llevar el peso y poder adaptarnos al contexto actual? Estos objetos portadores de la memoria y conocimiento, como las imágenes, internet, o los memoriales, etc. ¿Están sólo bajo una lógica del consumo inmediato?, o ¿es el tipo de uso más potenciado? ¿Qué relación establecemos con los memoriales? Monumentos creados con el fin de recordar. After the warlike events that devastated the world during the 20th century, specifically, from 1980, interest and the theoretical approach on the past and memory increased. Starting from this, the question to be dealt with in the present work is: what characteristics does our present have and how this determines some forms of access to the past. To then ask ourselves about the relationship that is established with memorials, that is, to what extent the context or conditions of the subject mediate his relationship with memory. Since the reflection on memory can be conditioned by the characteristics of our context: social acceleration. The approach that a subject belonging to the generations furthest away from what happened in the twentieth century may have differs greatly from the relationship that those who experienced the event or the consequences can have in a more immediate way. For this reason, we must ask ourselves: Have we - especially the younger generations - turned memory and knowledge into external objects to turn to and thus not carry the weight and be able to adapt to the current context? These objects that carry memory and knowledge, such as images, the internet, or memorials, etc. Are they only under a logic of immediate consumption? Or is it the most enhanced type of use? What relationship do we establish with the memorials? Monuments created in order to remember.


2019 ◽  
Vol 33 (67) ◽  
pp. 123-141
Author(s):  
Flaviano de Souza Alves

O homem consegue conversar com o mundo inteiro por meio da Internet, fazendo despertar para esta era de inovações e crescimento tecnológico. Embora pareça que, com o surgimento dessas redes, tenha-se estreitado laços entre pessoas de diversas partes do mundo, ao mesmo tempo, esta prática tem aumentado a vulnerabilidade das pessoas. O trabalho tem como objetivo mostrar a rede de atos criminosos existentes dentro da Deep Weeb. A justificativa para este estudo é o crescente interesse sobre o assunto, sobretudo nos meios acadêmicos, militares, nas áreas de Defesa e Segurança e em áreas policiais, visando também à grande necessidade de informar, analisar, investigar e alertar todos os cidadãos sobre os perigos e os riscos aos quais toda a sociedade está exposta. É necessário continuar com novas pesquisas e apontar novos mecanismos de combate para esses crimes cibernéticos, desenvolver melhores softwares (browser, antivírus, firewall etc.) e a configuração ideal desses softwares para acesso seguro a essa camada da rede. Na Deep Web depende de cada um escolher o que buscar.   Man mange to communicate with the entire world through the Internet and have awaked to this era of innovations and technological growth. Although it seems that ties between people from several parts of the world have been strengthened with the emergence of such networks, at the same time, this practice has increased the vulnerability of people. The paper aims to show the criminal acts network within the Deep Web. The rationale for this study is the rising interest on the subject, especially in the academic, military, defense and security areas and in police areas, seeking as well the great need to inform, analyze, investigate and alert all citizens about the dangers and the threats society has been exposed to. It is a need to continue with new researches and point out original mechanisms to combat these cyber crimes, develop better software (browser, antivirus, firewall, etc.) and its ideal configuration for a secure access to this network layer. At Deep Web, the search depends on everyone’s choice.   El hombre logra comunicarse con el mundo entero a través de Internet, haciendo despertar para esta era de innovaciones y crecimiento tecnológico. Aunque parezca que con el surgimiento de esas redes ha estrechado lazos entre personas de diversas partes del mundo, al mismo tiempo, esta práctica ha aumentado la vulnerabilidad de las personas. El trabajo tiene como objetivo de mostrar la red de actos criminales existentes dentro de Deep Weeb. La justificación para este estudio es el creciente interés sobre el tema, sobre todo en los medios académicos, en los militares, en las áreas de Defensa y Seguridad y en áreas policiales, buscando también la gran necesidad de informar, analizar, investigar y alertar a todos los ciudadanos sobre los mismos peligros y los riesgos a los que toda la sociedad está expuesta. Es necesario continuar con nuevas investigaciones y apuntar nuevos mecanismos de combate para esos crímenes cibernéticos, desarrollar mejores softwares (navegador, antivirus, firewall, etc.) y su configuración ideal para acceso seguro a esa capa de la red. En Deep web depende de lo que cada uno elija.


Author(s):  
Patrícia Costa dos Santos da Silva ◽  
Lívia Ferreira Oliveira ◽  
Mariana Ramos ◽  
Michele Aparecida Silva Maciel ◽  
Luana Araújo Macedo Scalia ◽  
...  

The COVID-19 pandemic has transformed the reality, made social isolation urgent aiming at reducing the contagion of the disease and, as a consequence, had to interrupt the classes and actions of extension projects in person. In this aspect, the Internet has become a possibility of interaction between teachers, nursing students and the community in an extension project university entitled: "Aromatherapy as a tool for coping in times of pandemic. Thus, the present study is a report of the authors' experience in the project of  aromatherapy as an activity for health promotion in times of pandemic by COVID-19. A descriptive qualitative report was carried out on the experiences of the authors with the use of a virtual platform as an alternative informative content on the subject, during this period. The project was carried out in five weeks, with three synchronous meetings, the programmatic content was guided by scientific evidence, with guidelines of great importance to the public assisted with the aim of promoting health and be a tool for coping in times of pandemic. Thus, access to health promotion and exchange of knowledge of the target audience of the extension project was expanded.


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