scholarly journals Trends in the Primary Incidence of Diseases of the Nervous System of the Kyrgyz Republic

2021 ◽  
Vol 7 (6) ◽  
Author(s):  
A. Samaganova ◽  
G. Chоyubekova ◽  
K. Sadamkulova

The high incidence of diseases of the nervous system indicates an untimely identified pathology and the further progression of diseases. The dynamics in the Kyrgyz Republic as a whole showed an increase in the primary incidence of diseases of the nervous system. In 2015, an increase in the indicator was noted by +2.1%, in 2017 by +11.2%, in 2018 by +0.7%. Cases of first detected epilepsy in dynamics, from 2015 to 2017, increased by +25.1%, +17.8%, +16.0%, respectively. For the first time, cases of lesions of individual nerves, nerve roots showed an increase trend in 2015 by +7.9%, in 2017 by +18.6%, in 2018 by +11.7%. The incidence of childhood cerebral palsy is characterized by an increase in 2015 by +9.8% and a sharp increase in 2018 by +156.5%. In Bishkek, the increase in the primary incidence of nervous diseases in 2017 and 2018 years was +12.1% and +13.8% in terms of growth rate, respectively. Cases of first reported epilepsy tended to rise in all years except 2019. Increase in 2015 by +27.5%, 2016 by +23.7%, 2017 by +2.1%, 2018 by + 34.1%. Cases of lesions of individual nerves, nerve roots tended to increase in 2016 by +2.6%, in 2017 by +22.3%, in 2019 by +2.3%. The incidence of childhood cerebral palsy is characterized by an increasing trend in all years except 2019, as for cases of epilepsy. In dynamics, growth was observed in 2015 by +13.5%, in 2016 by +73.0%, in 2017 by +11.1%, in 2018 by +556.0%. The revealed trends in the incidence of diseases of the nervous system dictate the need to increase the provision of the population with neuropathologists and improve the availability of neurological care to the population.

Author(s):  
Elena Mikhaylovna Chervonenko ◽  
Lina Yurievna Lagutkina

The article describes the process of tench growing (male and female species removed from set gear in the Volga river in the Astrakhan region) using experimental feedstuff "T", taking into account the fact that problems with artificial growing tench ( Тinca tinca ) appear first in the process of feeding when wild sires change to artificial food. The research took place on the base of the department of aquaculture and water bioresources of Astrakhan State Technical University in innovation centre "Bioaquapark - scientific and technical centre of aquaculture" in 2015. Special feed including components of animal origin - mosquito grab and sludge worm as an effective substitute to fish flour, as well as components of vegetable origin (carrot, parsley, pumpkin, wheatgrass) for domestication of tenches are offered for the first time. Food technology has been described. The exact composition of the formula, which is being licensed at the moment, is not disclosed. Feed "T", which has undergone biological analysis and is in accordance with organoleptic and physical standards was used for feeding tench female and male species during domestication period (60 days), along with food "Coppens" (Holland). Feed efficiency was determined according to survival and daily fish growth. Growth rate of females appeared more intensive than growth rate of males fed with experimental food "T". Daily growth changed depending on the types of food: from 0.3 ("Coppens") to 0.47 (experimental food) in females, from 0.25 ("Coppens") to 0.39 (experimental food) with males. Ability to survive among tench species fed with "Coppens" and experimental food made 60% and 100%, correspondingly. Nutricion of tench species with experimental food encouraged their domestication, which allowed using tench species in further fish breeding process in order to get offspring. The project was supported by the Innovation Promotion Fund in terms of the project "Development and implementation of the technique for the steady development of aquaculture: food "TechSA".


2021 ◽  
pp. 1-8
Author(s):  
Milan Zeleny

Most world economies are undergoing fundamental transformations of economic sectors, shifting their employed workforce through the secular sequence of (1. Agriculture⟶2. Industry⟶3. Services⟶4. Government). The productivity growth rate is the driving force. Most advanced economies have reached the final stages of the sequence. Assorted recessions, crises and stagnations are simply cofluent, accompanying phenomena. Crises might be cyclical, but economic evolution is unidirectional. Traditional economics can hardly distinguish phenomena of crisis from those of the transformation. Because there is no “fifth sector”, some economies are entering the phase of metamorphosis, for the first time in history. Metamorphosis is manifested through deglobalization, relocalization and autonomization of local and regional economies. We are entering the Age of Entrepreneurship.


2002 ◽  
Vol 13 (2) ◽  
pp. 698-710 ◽  
Author(s):  
Sylvie Ozon ◽  
Antoine Guichet ◽  
Olivier Gavet ◽  
Siegfried Roth ◽  
André Sobel

Stathmin is a ubiquitous regulatory phosphoprotein, the generic element of a family of neural phosphoproteins in vertebrates that possess the capacity to bind tubulin and interfere with microtubule dynamics. Although stathmin and the other proteins of the family have been associated with numerous cell regulations, their biological roles remain elusive, as in particular inactivation of the stathmin gene in the mouse resulted in no clear deleterious phenotype. We identified stathmin phosphoproteins inDrosophila, encoded by a unique gene sharing the intron/exon structure of the vertebrate stathmin andstathmin family genes. They interfere with microtubule assembly in vitro, and in vivo when expressed in HeLa cells. Drosophila stathmin expression is regulated during embryogenesis: it is high in the migrating germ cells and in the central and peripheral nervous systems, a pattern resembling that of mammalian stathmin. Furthermore, RNA interference inactivation ofDrosophila stathmin expression resulted in germ cell migration arrest at stage 14. It also induced important anomalies in nervous system development, such as loss of commissures and longitudinal connectives in the ventral cord, or abnormal chordotonal neuron organization. In conclusion, a single Drosophilagene encodes phosphoproteins homologous to the entire vertebrate stathmin family. We demonstrate for the first time their direct involvement in major biological processes such as development of the reproductive and nervous systems.


1974 ◽  
Vol 11 (03) ◽  
pp. 437-444 ◽  
Author(s):  
Benoit Mandelbrot

Luria and Delbrück (1943) have observed that, in old cultures of bacteria that have mutated at random, the distribution of the number of mutants is extremely long-tailed. In this note, this distribution will be derived (for the first time) exactly and explicitly. The rates of mutation will be allowed to be either positive or infinitesimal, and the rate of growth for mutants will be allowed to be either equal, greater or smaller than for non-mutants. Under the realistic limit condition of a very low mutation rate, the number of mutants is shown to be a stable-Lévy (sometimes called “Pareto Lévy”) random variable, of maximum skewness ß, whose exponent α is essentially the ratio of the growth rates of non-mutants and of mutants. Thus, the probability of the number of mutants exceeding the very large value m is proportional to m –α–1 (a behavior sometimes referred to as “asymptotically Paretian” or “hyperbolic”). The unequal growth rate cases α ≠ 1 are solved for the first time. In the α = 1 case, a result of Lea and Coulson is rederived, interpreted, and generalized. Various paradoxes involving divergent moments that were encountered in earlier approaches are either absent or fully explainable. The mathematical techniques used being standard, they will not be described in detail, so this note will be primarily a collection of results. However, the justification for deriving them lies in their use in biology, and the mathematically unexperienced biologists may be unfamiliar with the tools used. They may wish for more details of calculations, more explanations and Figures. To satisfy their needs, a report available from the author upon request has been prepared. It will be referred to as Part II.


1994 ◽  
Vol 342 ◽  
Author(s):  
S.C. Sun ◽  
L.S. Wang ◽  
F.L. Yeh ◽  
T.S. Lai ◽  
Y.H. Lin

ABSTRACTIn this paper, a detailed study is presented for the growth kinetics of rapid thermal oxidation of lightly-doped silicon in N2O and O2 on (100), (110), and (111) oriented substrates. It was found that (110)-oriented Si has the highest growth rate in both N2O and dry O2, and (100) Si has the lowest rate. There is no “crossover” on the growth rate of rapid thermal N2O oxidation between (110) Si and (111) Si as compared to oxides grown in furnace N2O. Pressure dependence of rapid thermal N2O oxidation is reported for the first time. MOS capacitor results show that the low-pressure (40 Torr) N2O-grown oxides have much less interface state generation and charge trapping under constant current stress as compared to oxides grown in either 760 Torr N2O or O2 ambient.


Parasitology ◽  
1996 ◽  
Vol 113 (6) ◽  
pp. 559-565 ◽  
Author(s):  
M. K. S. Gustafsson ◽  
A. M. Lindholm ◽  
N. B. Terenina ◽  
M. Reuter

SUMMARYThe free radical nitric oxide (NO), which is synthesized by nitric oxide synthase (NOS), has recently been discovered to function as a neuronal messenger. The presence of NOS was detected in the nervous system of adult Hymenolepis diminuta with NADPH-diaphorase (NADPH-d) histochemistry. The NADPH-d histochemical reaction is regarded as a selective marker for NOS in neuronal tissue. NADPH-d staining was observed in nerve fibres in the main and minor nerve cords and the transverse ring commissures, and in cell bodies in the brain commissure, along the main nerve cords, in the suckers and the rostellar sac. NADPH-d staining was also observed in the wall of the internal seminal vesicle and the genital atrium. The pattern of NADPH-d staining was compared with that of the 5-HT immunoreactive nervous elements. The NADPH-d staining reaction and the 5-HT immunoreactivity occur in separate sets of neurons. This is the first time the NADPH-d reaction has been demonstrated in the nervous system of a flatworm, indicating that NOS is present and that NO can be produced at this level of evolution.


PEDIATRICS ◽  
1952 ◽  
Vol 9 (2) ◽  
pp. 204-211
Author(s):  
HERMAN YANNET ◽  
FRANK HORTON

The relative importance of the hypotonic type of cerebral palsy among the mentally defective is stressed. This type of cerebral palsy manifests itself in either of three clinical pictures with some overlapping, namely, atonic, ataxic and athetoid. The etiology is variable in each of these groups and may be effective in either the prenatal, paranatal or postnatal periods. The severity of the mental defect, the high incidence of convulsive disorders, and the tendency toward microcephaly point towards the widespread nature of the pathologic process regardless of etiology. The syndrome of atonic diplegia, as herein described, is probably invariably associated with the more severe degrees of mental deficiency.


2006 ◽  
Vol 41 (4) ◽  
pp. 202
Author(s):  
Pertin Sianturi ◽  
Amir Sarifuddin ◽  
Bistok Saing

Epilepsy is a chronic condition due to cerebral function disorders. Epilepsy occurs as a common complication of many neurological disorders such as cerebral palsy (CP) that can affect further brain damage especially if they are with prolonged seizure. The incidence of epilepsy among patients with CP varies between 25-35%. The high incidence of epilepsy among patients with CP suggests that this disorder has common or related origins. We carried out the retrospective study to determine incidence of epilepsy among patients with CP registered within July 1988 to June 1998 in YPAC Medan and to determine whether the incidence of epilepsy differed according to type of CP. Data were compiled from medical records, including name, sex, parity, mothers age, prenatal, perinatal, and postnatal history, and EEG results. Data were analyzed using statistical computer program and its significance was evaluated by chi square test at p < 0,05. There were 67 cases with CP, 53 cases spastic CP, 13 cases mixed CP and one case dyskinetic CP. Of the 67 cases CP, 47,8% male, 52,2% female and mean age 50,3 (SD 36,9) months. There were 25 (37,3%) patients CP associated with epilepsy, 72% general seizures, 20% partial seizures, and 8% infantile spasms. The incidence of epilepsy was significant different among patients with CP associated with type of CP and gestasional age, p < 0,05. We concluded that incidence of epilepsy among patients with CP in YPAC Medan was 37,3% and significantly different among patients with CP according to type CP and gestasional age.


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