scholarly journals Methods of Experimental Modeling of Metastasis

Biomeditsina ◽  
2021 ◽  
Vol 17 (4) ◽  
pp. 44-49
Author(s):  
N. Yu. Timofeeva ◽  
N. V. Bubnova ◽  
G. Yu. Struchko ◽  
O. Yu. Kostrova ◽  
I. S. Stomenskaya
Keyword(s):  
Cause Of Death ◽  
Tumor Metastasis ◽  
Growth Characteristic ◽  
Modern Medicine ◽  
Malignant Neoplasms ◽  
Metastasis Formation ◽  
Malignant Growth ◽  
Experimental Conditions ◽  
Advantages And Disadvantages ◽  
Long Time

One of the main problems of modern medicine is cancer, which is the second leading cause of death after cardiovascular disease. Malignant neoplasms have been known for a long time; however, their study still presents significant difficulties. Modeling of malignant processes in animals allow researchers to study tumors and the main patterns of malignant growth characteristic of animals and humans. The main cause of death in malignant neoplasms is the process of metastasis formation, which remains to be understood in detail. The study of metastatic processes is one of the most important tasks of oncology. To this end, various models of tumor metastasis are created. The article reviews literature data on the most popular models of metastasis in experimental conditions. The advantages and disadvantages of the main approaches to modeling metastasis are evaluated.

scholarly journals RECENT ADVANCES IN THE STUDY OF THE STEM CELLS MIGRATION METHODS

2013 ◽  
Vol 68 (9) ◽  
pp. 46-51 ◽  
Author(s):  
A. F. Poveshchenko ◽  
O. V. Poveshchenko ◽  
V. I. Konenkov
Keyword(s):  
Stem Cells ◽  
Specific Binding ◽  
The Body ◽  
Time Interval ◽  
Clinical Settings ◽  
Experimental Conditions ◽  
Best Available Techniques ◽  
Advantages And Disadvantages ◽  
Non Invasive ◽  
Long Time

Review is devoted to a comparative analysis of stem cells migration methods for studying in experimental conditions and clinics, assessing their strengths and weaknesses. It is impossible to single out any one preferred method for studying the migration of stem cells. Each method has its own set of advantages and disadvantages. X-ray methods " suffer" from non-specific binding of contrast marks, followed by rapid degradation and the release of the body. If it is necessary to study the migration of the transplanted stem cells for a long time interval, the visualization of the reporter gene is the best available techniques, since it can provide a non-invasive real time monitoring of the location in the tissue and stem cells isolated help assess their viability and proliferation. The most attractive of the agents for monitoring - endogenous, i.e. natural constituents stem cells, for example, genetic markers. Criteria for the application of methods to study migration in clinical and experimental results have significant differences. The main criteria for the methods of the study of cell migration in clinical settings, it must be biocompatible, safe, non-toxic, non-invasive. Accordingly, the main criteria for the experimental methods for studying the migration will be accuracy, the ability to quantify the long-term migration of cells and stability of the "label".

scholarly journals Scanning and Actuation Techniques for Cantilever-Based Fiber Optic Endoscopic Scanners—A Review

Sensors ◽  
2021 ◽  
Vol 21 (1) ◽  
pp. 251
Author(s):  
Mandeep Kaur ◽  
Pierre M. Lane ◽  
Carlo Menon
Keyword(s):  
Micro Electro Mechanical System ◽  
Modern Medicine ◽  
Image Resolution ◽  
Optical Fields ◽  
Scanning Method ◽  
Advantages And Disadvantages ◽  
Image Area ◽  
Technical Advances ◽  
Scanning Fiber

Endoscopes are used routinely in modern medicine for in-vivo imaging of luminal organs. Technical advances in the micro-electro-mechanical system (MEMS) and optical fields have enabled the further miniaturization of endoscopes, resulting in the ability to image previously inaccessible small-caliber luminal organs, enabling the early detection of lesions and other abnormalities in these tissues. The development of scanning fiber endoscopes supports the fabrication of small cantilever-based imaging devices without compromising the image resolution. The size of an endoscope is highly dependent on the actuation and scanning method used to illuminate the target image area. Different actuation methods used in the design of small-sized cantilever-based endoscopes are reviewed in this paper along with their working principles, advantages and disadvantages, generated scanning patterns, and applications.

Some Experiments on Wet Steam Flow Visualization in Large Steam Turbine Blading

1976 ◽  
Vol 98 (3) ◽  
pp. 573-577 ◽  
Author(s):  
J. Krzyz˙anowski ◽  
B. Weigle
Keyword(s):  
Steam Turbine ◽  
Steam Flow ◽  
Light Sources ◽  
Phase Flow ◽  
Wet Steam ◽  
Experimental Conditions ◽  
Advantages And Disadvantages ◽  
Primary Droplet ◽  
Last Stage ◽  
Wet Steam Flow

In a series of experiments aimed at the visualization of the wet steam flow in the exhaust part of a 200 MW condensing steam turbine a set of periscopes and light sources was used. The aim of the experiment was: 1 – The investigation of the liquid-phase flow over the last stage stator blading of the turbine mentioned. 2 – The investigation of the gaseous-phase flow through the last stage blading at full and part load. The first part of the program partially failed due to the opaqueness of the wet steam atmosphere for the turbine load higher than 10–20 MW. The detailed experimental conditions will be described. An assessment of the primary droplet size will also be given. The preliminary results of the second part of the program will be outlined. The advantages and disadvantages of the equipment used will be discussed.

THE EFFECTS OF ELECTROACUPUNCTURE COMBINED WITH ACUPRESSURE POINTS, MASSAGE TREATMENT AND “DOC HOAT TANG KY SINH” REMEDY ON TREATING SCIATICA DUE TO LUMBAR SPONDYLOSIS

2020 ◽  
pp. 105-111
Author(s):  
Giang Huynh Huong ◽  
Tan Nguyen Thi ◽  
Hung Nguyen Van
Keyword(s):  
Traditional Medicine ◽  
Modern Medicine ◽  
Common Disease ◽  
Working Ability ◽  
Treatment Results ◽  
Lumbar Spondylosis ◽  
Before And After ◽  
Massage Treatment ◽  
Long Time ◽  
Methods Of Treatment

Background: Sciatica due to lumbar spondylosis is a common disease syndrome, include pathological signs from lumbar spine and sciatic nerve. It occurs for a long time and affects to working ability and daily life. Currently there are many methods of treatment with modern medicine and traditional medicine. Electroacupuncture combined with acupressure point, massage treatment and “Doc hoat tang ky sinh” remedy is a highly effective method on treating sciatica due to lumbar spondylosis. Objectives: To evaluate the effectives of electroacupuncture combined with acupressure point, massage treatment and “Doc hoat tang ky sinh” remedy on treating sciatica due to lumbar spondylosis. Materials and Method: A total of 43 patients was diagnosed sciatica caused by lumbar spondylosis who treated at Thua Thien Hue Traditional Medicine Hospital. The study was designed by method of prospective study, assessed the results before and after the treatment. Results: Very good: 34.9%; good: 34.9%; average 7%. There was not any unexpected effects observed in this trial. Conclusion: Electroacupuncture combined with acupressure point, massage treatment and “Doc hoat tang ky sinh” remedy is a effective method on treating sciatica caused by lumbar spondylosis. Key words: sciatica, lumbar spondylosis, acupuncture, electroacupuncture, acupressure point, massage treatment

scholarly journals Ten Famous Composers of the Romantic Era and their Cause of Death

2021 ◽  
Author(s):  
Ernest K.J. Pauwels
Keyword(s):  
Medical Research ◽  
Cause Of Death ◽  
21St Century ◽  
Causes Of Death ◽  
Human Life ◽  
Modern Medicine ◽  
Expression Of Emotion ◽  
The World ◽  
Romantic Era ◽  
Clinically Significant

The musical composers in the Romantic Era (1800-1910) strived for compositions that expressed human life, including happiness, harmony and despair. They lived in a period in which freedom of thinking, expression of emotion and inspiration by nature predominate. During this period, intensive trading with other parts of the world brought new microorganisms along, which made infections and epidemics very common. This article serves to address the cause of death and relevant biographic data of a number of well- known Romantic composers. Primarily, this review refers to clinically significant findings using reports that were retrieved from Pubmed, Embase and Google over the 19th, 20th and 21st century till 14th June 2021. Here, this text dwells on diseases and the cause of death of ten composers, namely Mozart, Beethoven, Chopin, Schubert, Schumann, Mendelssohn, Brahms, Liszt, Mahler and Bruckner. It is evident that, in the sight of modern medicine, symptoms and forensic facts are not complete, but witnesses' reports and recent medical research have provided passable and plausible clarity. Although many questions will remain unanswered, it appears that the diseases of these composers and their causes of death have their origins in alcohol abuses, age, epidemics (like tuberculosis) and syphilis.

scholarly journals Alumnol in gynecology

2020 ◽  
Vol 11 (4) ◽  
pp. 389-402
Author(s):  
V. V. Poteenko
Keyword(s):  
Aqueous Solution ◽  
Zinc Chloride ◽  
Uterine Cavity ◽  
Modern Medicine ◽  
Pelvic Peritoneum ◽  
Long Time ◽  
Recent Origin

The proposed method for the treatment of diseases of the uterus, its appendages and pelvic peritoneum consists in injecting into the uterus (its cavity) a solution of alumnol'a (alumnol 2.5, iodine tincture and purified alcohol 25.0 each). The idea of such a method of treatment, like very much in modern medicine, is not new, for example, for a very long time, for endometritis, injections into the uterine cavity of iodine tincture, an aqueous solution of zinc chloride, etc. have been used. The use of alumnol for this purpose is of a very recent origin.

scholarly journals A comparative study of handwriting and computer typing in note-taking by university students

Comunicar ◽  
2016 ◽  
Vol 24 (48) ◽  
pp. 101-107 ◽  
Author(s):  
Estíbaliz Aragón-Mendizábal ◽  
Cándida Delgado-Casas ◽  
José-I. Navarro-Guzmán ◽  
Inmaculada Menacho-Jiménez ◽  
Manuel-F. Romero-Oliva
Keyword(s):  
Health Science ◽  
Science Students ◽  
Education Students ◽  
Experimental Conditions ◽  
Health Science Students ◽  
Advantages And Disadvantages ◽  
Common Strategy ◽  
Pencil And Paper ◽  
Los Grupos ◽  
Estudiantes Universitarios

Taking notes is a common strategy among higher education students, and has been found to affect their academic performance. Nowadays, however, the use of computers is replacing the traditional pencil-and-paper methodology. The present study aims to identify the advantages and disadvantages associated with the use of computer (typing) and pencil-and-paper (handwriting) for taking notes by college students. A total of 251 social and health science students participated in the study. Two experimental conditions were chosen: taking notes by hand (n=211), and taking notes by computer (n=40). Those that used computer-written notes performed better on tasks based on reproducing the alphabet, writing sentences, and recognizing words (p<.05). However, those using handwritten notes performed better on free recall tasks (p<.05). Differences between the two conditions were statistically significant rejecting the hypothesis of equality between groups (X2=60.98; p<.0001). In addition, the discriminant analysis confirmed that 77.3% of students were correctly classified by the experimental conditions. Although the computer allowed for greater velocity when taking notes, handwriting enhanced students’ grades when performing memory tasks. La toma de apuntes es una estrategia generalizada del alumnado de Educación Superior y se ha constatado su influencia en el rendimiento académico. El uso del ordenador está desplazando al método tradicional de lápiz y papel. El presente estudio pretende arrojar luz sobre las ventajas y los inconvenientes derivados del uso de uno u otro método en la toma de apuntes en las aulas universitarias. Un total de 251 estudiantes universitarios de ciencias sociales y ciencias de la salud participaron en el estudio. Se plantearon dos condiciones experimentales: toma de notas de forma manual (n=211) y de manera electrónica (n=40). Se hallaron diferencias a favor del grupo que usó el ordenador en las tareas basadas en completar el abecedario, escribir frases y reconocer palabras anotadas previamente (p<.05). Sin embargo, en la tarea de recuerdo libre los resultados reflejaron un mejor desempeño del grupo que tomó notas manualmente (p<.05). Se rechazó la hipótesis de igualdad entre los grupos (X2=60,98; p<.0001). Además, el análisis discriminante confirmó que el 77,3% de los alumnos fueron clasificados correctamente según su condición experimental. El uso del ordenador resultó muy útil cuando se trataba de anotar datos con rapidez; sin embargo, en las tareas de recuerdo los alumnos de escritura manual obtuvieron mejores puntuaciones que los de escritura electrónica.

Review on critical technology development of avian radar system

2022 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Weishi Chen ◽  
Yifeng Huang ◽  
Xianfeng Lu ◽  
Jie Zhang
Keyword(s):  
Technology Development ◽  
Time Integration ◽  
Radar System ◽  
Content Type ◽  
Advantages And Disadvantages ◽  
Detection And Tracking ◽  
Critical Technology ◽  
Long Time ◽  
Long Time Integration ◽  
Target Characteristics

Purpose This paper aims to review the critical technology development of avian radar system at airports. Design/methodology/approach After the origin of avian radar technology is discussed, the target characteristics of flying birds are analyzed, including the target echo amplitude, flight speed, flight height, trajectory and micro-Doppler. Four typical airport avian radar systems of Merlin, Accipiter, Robin and CAST are introduced. The performance of different modules such as antenna, target detection and tracking, target recognition and classification, analysis of bird information together determines the detection ability of avian radar. The performances and key technologies of the ubiquitous avian radar are summarized and compared with other systems, and their applications, deployment modes, as well as their advantages and disadvantages are introduced and analyzed. Findings The ubiquitous avian radar achieves the long-time integration of target echoes, which greatly improves detection and classification ability of the targets of birds or drones, even under strong background clutter at airport. In addition, based on the big data of bird situation accumulated by avian radar, the rules of bird activity around the airport can be mined to guide the bird avoidance work. Originality/value This paper presented a novel avian radar system based on ubiquitous digital radar technology. The authors’ experience has confirmed that this system can be effective for airport bird strike prevention and management. In the future, the avian radar system will see continued improvement in both software and hardware, as the system is designed to be easily extensible.

scholarly journals Shark–Cetacean trophic interaction, Duinefontein, Koeberg, (5 Ma), South Africa

2015 ◽  
Vol Volume 111 (Number 11/12) ◽  
Author(s):  
Romala Govender ◽  
Keyword(s):  
South Africa ◽  
Cause Of Death ◽  
West Coast ◽  
Trophic Interaction ◽  
The West ◽  
Carcharodon Carcharias ◽  
Inverted Position ◽  
Bite Marks ◽  
Shark Teeth ◽  
Long Time

Abstract This study forms part of a larger project to reconstruct the Mio-Pliocene marine palaeoenvironment along South Africa’s west coast. It documents the shark–cetacean trophic interaction during the Zanclean (5 Ma) at Duinefontein (Koeberg). The damage described on the fragmentary cetacean bones was compared with similar damage observed on fossils from Langebaanweg, a Mio-Pliocene site on the west coast of South Africa, and data present in the literature. This comparison showed that the damage was the result of shark bites. The state of preservation makes it difficult to determine if the shark bite marks were the cause of death or as a result of scavenging. The presence of the bite marks on the bone would, however, indicate some degree of skeletonisation. Bite marks on some cranial fragments would suggest that the cetacean’s body was in an inverted position typical of a floating carcass. The preservation of the material suggests that the bones were exposed to wave action resulting in their fragmentation as well as abrasion, polishing and rolling. It also suggests that the cetacean skeletons were exposed for a long time prior to burial. The morphology of the bites suggests that the damage was inflicted by sharks with serrated and unserrated teeth. Shark teeth collected from the deposit include megalodon (Carcharodon megalodon), white (Carcharodon carcharias) as well as mako (Isurus sp. and Cosmopolitodus hastalis) sharks, making these sharks the most likely predators/scavengers.

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