Features of management of patients with seborrheic dermatitis

2021 ◽  
pp. 29-32
Author(s):  
E. M. Markelova
Keyword(s):  
Seborrheic Dermatitis ◽  
The Body ◽  
High Concentration ◽  
Long Time ◽  
Inflammatory Drugs ◽  
Malassezia Spp ◽  
Erythematous Plaques ◽  
Yeast Fungus

Seborrheic dermatitis (SD) is a chronic recurrent inflammatory skin disease caused by changes of quantitative and qualitative sebum characteristics. SD comes out by appearing of erythematous plaques with sense of itch and peeling skin in areas with high concentration of sebaceous glands: on the scalp, face, upper part of the body and in the folds of skin. Due to the fact that the development of the SD is promoted by the colonization of the skin with a lipophilic yeast fungus Malassezia spp., in the treatment of uncomplicated simple forms of the disease can be applied external antifungal medicines, topical glucocorticosteroids and anti-inflammatory drugs of non-steroidal origin. Systemic therapy is also used in severe course of seborrheic dermatitis and in the treatment of forms, resistant to external therapy. In the treatment of persistent and long-term forms of SD, systemic antifungal agents and systemic retinoids are used, which allow for a long time to achieve regression of skin rashes and significantly improve the quality of life of the patient.

scholarly journals Developing WHO guidelines: Time to formally include evidence from mathematical modelling studies

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1584 ◽  
Author(s):  
Matthias Egger ◽  
Leigh Johnson ◽  
Christian Althaus ◽  
Anna Schöni ◽  
Georgia Salanti ◽  
...  
Keyword(s):  
Mathematical Modelling ◽  
The Body ◽  
World Health ◽  
Who Guidelines ◽  
Problem Model ◽  
Assessment Development ◽  
Modelling Studies ◽  
Health Organization

In recent years, the number of mathematical modelling studies has increased steeply. Many of the questions addressed in these studies are relevant to the development of World Health Organization (WHO) guidelines, but modelling studies are rarely formally included as part of the body of evidence. An expert consultation hosted by WHO, a survey of modellers and users of modelling studies, and literature reviews informed the development of recommendations on when and how to incorporate the results of modelling studies into WHO guidelines. In this article, we argue that modelling studies should routinely be considered in the process of developing WHO guidelines, but particularly in the evaluation of public health programmes, long-term effectiveness or comparative effectiveness.  There should be a systematic and transparent approach to identifying relevant published models, and to commissioning new models.  We believe that the inclusion of evidence from modelling studies into the Grading of Recommendations Assessment, Development and Evaluation (GRADE) process is possible and desirable, with relatively few adaptations.  No single “one-size-fits-all” approach is appropriate to assess the quality of modelling studies. The concept of the ‘credibility’ of the model, which takes the conceptualization of the problem, model structure, input data, different dimensions of uncertainty, as well as transparency and validation into account, is more appropriate than ‘risk of bias’.

Nurse, 30 years’ experience, Norway

2020 ◽  
pp. 247-251
Author(s):  
Markus Reuber ◽  
Gregg H. Rawlings ◽  
Steven C. Schachter
Keyword(s):  
Young People ◽  
Children And Adolescents ◽  
Youth Culture ◽  
Epileptic Seizures ◽  
The Body ◽  
Total Load ◽  
Long Time ◽  
The Mind ◽  
People Today

This chapter focuses on the experience of a nurse when working with children and adolescents with Non-Epileptic Seizures (NES). Young people today have challenges on many levels, and for some, the total load becomes so great that they develop “seizures” for which a biological cause cannot be identified. Young people who develop NES have often been overloaded for a long time, many describing family problems, long-term bullying problems, exclusion or problems at school. The nurse is also increasingly meeting young people who struggle to adapt to youth culture. They are exhausted from trying to find a balance in their lives—a balance between achievement and rest, between their own needs and society’s demands, between “what the mind wants” and “what the body can tolerate.” Some come from families who have strong ideals that are not compatible with youth culture. This can result in a loyalty conflict that seems impossible to solve.

The Different Impacts on the Long-Term Survival of Tunneled Internal Jugular Hemodialysis Catheters Based on Tip Position and Laterality

2017 ◽  
Vol 43 (4) ◽  
pp. 315-320 ◽  
Author(s):  
Vedran Premuzic ◽  
Drazen Perkov ◽  
Ranko Smiljanic ◽  
Bruna Brunetta Gavranic ◽  
Bojan Jelakovic
Keyword(s):  
Superior Vena ◽  
Vena Cava ◽  
The Body ◽  
Term Survival ◽  
Catheter Tip ◽  
Tip Position ◽  
The Impact

Background/Aims: The aim of this study was to examine the impact of different catheter tip positions on the life of the catheter, dysfunction, infection, and quality of hemodialysis and possible differences between the access site laterality in jugular-tunneled hemodialysis catheters. Methods: Catheters were evaluated for the following parameters: place of insertion, time of insertion, duration of use, and reason for removal. In all patients, the catheter tip position was checked using an X-ray. Results: The mean duration of implanted catheters with the tip placed in the cavo-atrial junction and right atrium was significantly longer. There were no differences in catheter functionality at follow-up or complications based on catheter laterality for each catheter tip position. Conclusion: According to our results, the localization of the catheter tip in superior vena cava still remains the least preferable method. Our results showed that the main factor responsible for better catheter functionality was not laterality but the depth to which the catheter tip is inserted into the body.

scholarly journals Developing WHO guidelines: Time to formally include evidence from mathematical modelling studies

F1000Research ◽  
2018 ◽  
Vol 6 ◽  
pp. 1584 ◽  
Author(s):  
Matthias Egger ◽  
Leigh Johnson ◽  
Christian Althaus ◽  
Anna Schöni ◽  
Georgia Salanti ◽  
...  
Keyword(s):  
Mathematical Modelling ◽  
The Body ◽  
World Health ◽  
Who Guidelines ◽  
Problem Model ◽  
Assessment Development ◽  
Modelling Studies ◽  
Health Organization

In recent years, the number of mathematical modelling studies has increased steeply. Many of the questions addressed in these studies are relevant to the development of World Health Organization (WHO) guidelines, but modelling studies are rarely formally included as part of the body of evidence. An expert consultation hosted by WHO, a survey of modellers and users of modelling studies, and literature reviews informed the development of recommendations on when and how to incorporate the results of modelling studies into WHO guidelines. In this article, we argue that modelling studies should routinely be considered in the process of developing WHO guidelines, but particularly in the evaluation of public health programmes, long-term effectiveness or comparative effectiveness.  There should be a systematic and transparent approach to identifying relevant published models, and to commissioning new models.  We believe that the inclusion of evidence from modelling studies into the Grading of Recommendations Assessment, Development and Evaluation (GRADE) process is possible and desirable, with relatively few adaptations.  No single “one-size-fits-all” approach is appropriate to assess the quality of modelling studies. The concept of the ‘credibility’ of the model, which takes the conceptualization of the problem, model structure, input data, different dimensions of uncertainty, as well as transparency and validation into account, is more appropriate than ‘risk of bias’.

scholarly journals Considerations for Continuing Semielective and Emergency Otolaryngological Procedures During the COVID-19 Pandemic

2020 ◽  
Vol 100 (1) ◽  
pp. 19-25
Author(s):  
Sarina K. Mueller ◽  
Maximilian Traxdorf ◽  
Konstantinos Mantsopoulos ◽  
Antoniu-Oreste Gostian ◽  
Matti Sievert ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Emergency Surgery ◽  
Transmission Rate ◽  
Medical Personnel ◽  
Human Beings ◽  
Threatening Condition ◽  
Long Time ◽  
Life Threatening

Introduction: During the COVID-19 pandemic, worldwide over 600,000 human beings died due to the cause of the disease. In order to deescalate the transmission rate and to avoid crush loading the countries medical health systems social distancing, face masks, and lockdowns have been considered essential by the majority of governments. Whereas some countries have highly reduced or completely stopped otorhinolaryngological procedures, other countries have continued selected surgeries. The objective of this study was to analyze procedures and outcomes of continuing semielective and emergency surgeries during the COVID-19 pandemic. Methods: Retrospective analysis of n = 750 patients who received semi-elective or emergency surgery between March 26 and June 16, 2020, in the Otolaryngology Department of the Friedrich-Alexander-University of Erlangen-Nürnberg. All patients were screened for COVID symptoms and swabbed for SARS-CoV-2 prior to surgery. Results: Of the n = 750 patients, n = 699 patients received semielective surgery and n = 51 emergency surgery. For 27 patients, the swab result could not be awaited due to a life-threatening condition. In these cases, surgery was performed in full protective equipment. No patient was tested positive during or after the surgery (follow-up 45 to 127 days). No member of the medical personnel showed symptoms or was tested positive after contact with patients. Due to the continuation of surgeries, patients’ lives were saved and improvement of long-term quality-of-life and outcomes is anticipated. Conclusions: Continuing selected otorhinolaryngological surgeries is crucial for patients’ health, survival, and long-time quality of life, yet, the protection of the medical personnel has to be granted.

scholarly journals MASALAH TIDUR ANAK DENGAN LEUKEMIA LIMFOBLASTIK AKUT DALAM MENJALANI KEMOTERAPI FASE INDUKSI

2019 ◽  
Vol 6 (1) ◽  
pp. 68-73
Author(s):  
Andrye Fernandes
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Sleep Disorders ◽  
Sleep Problems ◽  
Lymphoblastic Leukemia ◽  
Repeated Measurements ◽  
Induction Phase ◽  
Quality Of Sleep ◽  
Long Time

Chemotherapy has an effect on the occurrence of sleep disorders in children who suffer from acute lymphoblastic leukemia. Sleep disorders experienced by children have an impact on optimizing the long-term quality of life of children. This study aims to describe sleep problems that occur in children suffering from acute lymphoblastic leukemia who undergo induction phase chemotherapy. The design of this study was descriptive analytic with repeated measurements of sleep disorders in children aged 7-18 years (n = 62). Data collection was carried out for 7 days, that is, one day before, five days during, and one day after chemotherapy. The results of data analysis found that children have > 15 minutes to fall asleep, children have less than normal amounts of sleep (the number of hours of sleep is normal, school age: 9-11 hours / day, adolescence: 8-10 hours / day) and there was a decrease in the quality of sleep scores. In conclusion, there are sleep disorders that occur in children, namely children have less time to sleep, children need a long time to be able to fall asleep, and children experience a decrease in the quality of sleep. The need for exploration of interventions to facilitate efficient sleep according to the stages of child development.

scholarly journals Urban Mining of e-Waste and the Role of Consumers

2021 ◽  
Author(s):  
Dimitris Georgantzis Garcia ◽  
Sven Kevin van Langen
Keyword(s):  
Consumer Behaviour ◽  
Final Section ◽  
Keyword Search ◽  
Survey Methods ◽  
The Body ◽  
Urban Mining ◽  
Closed Loop Supply Chains

This chapter adds to the body of literature on the Circular Economy (CE), urban mining, and their intersection with consumer behaviour, by first providing a review of existing and emergent EU regulations aimed towards enhancing the collection rate of household WEEE. The fast growth of the EEE waste stream and its potential for Urban Mining as well as the inability of WEEE collection to keep up with the growth of the EEE industry is showcased with statistical data. The final section critically analyses the literature the intersection between consumer behaviour and closed-loop supply chains for EEE, identified through a systematic keyword search to ensure replicability. The findings point at a lack of theoretical, methodological and product-case heterogeneity among the identified sources, with most of them employing the Theory of Planned Behaviour and survey methods and focusing on mobile phones or general WEEE. While the literature suggests important behavioural differences across EEE categories, this was not representatively explored. The final section contributes to filling this gap by developing a taxonomy of EEE categories based on characteristics that may predispose consumer behaviour. The identified dimensions are: size, involvement, long-term reliability expectations, value type, internet access, multifunctionality, the quality of being outdated and social meaning.

scholarly journals Nab-paclitaxel in Treatment of Metastatic Breast Cancer

2019 ◽  
Vol 2 (17) ◽  
pp. 12-18
Author(s):  
E. I. Kovalenko ◽  
E. V. Artamonova
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Metastatic Breast ◽  
New Drugs ◽  
High Concentration ◽  
Sequential Administration ◽  
Previously Treated ◽  
Significant Stage

Despite the development of new systems for the treatment of metastatic breast cancer (mBC), chemotherapy remains an integral and significant stage of treatment for any molecular tumor subtype. In accordance with modern concepts, the optimal strategy of therapy in the vast majority of cases of mBC is the sequential administration of cytostatics in mono modes. This approach allows long-term control of tumor growth, translating pathology into a chronic discharge and maintaining a high quality of life. The emergence of new drugs or innovative dosage forms of existing cytostatics expands the possibilities of treatment of this chronic disease and allows long-term control over the disease. One of such new options was nab-paclitaxel, nano-dispersed paclitaxel stabilized with albumin. This dosage form provides active transport of the drug through the vascular endothelium with the creation of its high concentration in the tumor tissue. Clinical studies comparing nab-paclitaxel with traditional taxanes (paclitaxel and docetaxel) demonstrated high efficacy and safety of the drug both in a wide population of patients and in individual subgroups, including patients previously treated with anthracycline taxane, cases with aggressive disease, lesions of visceral organs, elderly patients and others. In addition, due to its unique formula, the drug does not cause hypersensitivity reactions, differing from traditional These taxanes are easy to use and safe. The lack of need for premedication with dexamethasone allows it to be prescribed for such comorbidities as severe hypertension, diabetes mellitus, stomach ulcer and duodenal ulcer, etc., and also successfully combine it with inhibitors of control points of the immune response, which confidently removes the drug on arena of immuno-oncology.

scholarly journals GENERALIZED ARGINIA

2018 ◽  
Vol 21 (2) ◽  
pp. 101-105
Author(s):  
Alexander B. Krivosheev ◽  
L. A Khvan ◽  
D. N Bobokhidze ◽  
I. A Krivosheeva ◽  
D. V Morozov ◽  
...  
Keyword(s):  
Food Supplement ◽  
The Body ◽  
Review Of Literature ◽  
Internal Organs ◽  
Skin Hyperpigmentation ◽  
Comprehensive Examination ◽  
Term Administration ◽  
Inflammatory Drugs ◽  
The Moment

A brief review of literature on the problem of argyria is presented. Hyperpigmentation of the skin in 10-20% of cases has an iatrogenic cause. Hyperpigmentation of the skin can form on the background of taking non-steroidal anti-inflammatory drugs, amiodarone, cytostatics, antimalarials, etc. Systemic deposition of silver in various organs and tissues is known as generalized argyria. The disease is caused by the prolonged use of compounds containing silver (lapis pencil, silver nitrate, etc.). Clinically, generalized arginia is characterized by the gradual appearance of ashy-bluish coloration of the skin of open areas of the body (face, neck) and nail plates of the phalanges of the hands. The period from the moment of the beginning of reception of preparations of silver and before occurrence of the first dermatological changes varies on the average from 1 year to 5 years. Generalized argiria is a rare disease. This is due to the limited use of silver drugs in clinical practice, as well as the improvement of technological processes in pharmacological production. The patient’s own observation with generalized arginia formed against the background of the long-term administration of the drug Argovit-S, whose silver content is 0.75-0.85 mg/ml, is analyzed. The patient took the drug alone as a food supplement for 25 years. The diagnosis of generalized arginia is verified clinically, but is confirmed necessarily in the course of histological examination. It is shown that argyria is not only the iatrogenic cause of skin hyperpigmentation, but a serious risk factor for the manifestation and progression of liver cirrhosis. Patients with generalized arginia should undergo a comprehensive examination in order to verify the serious pathology of internal organs.

scholarly journals Personalization of the use of non-steroidal anti-inflammatory drugs for musculoskeletal diseases. Resolution on the results of the Meeting of Experts of December 13, 2017

2018 ◽  
pp. 76-84 ◽  
Author(s):  
A. E. Karateev ◽  
A. M. Lila ◽  
I. S. Dydykina ◽  
P. R. Kamchatnov ◽  
S. O. Mazurenko ◽  
...  
Keyword(s):  
Musculoskeletal Diseases ◽  
Modern Medicine ◽  
Individual Characteristics ◽  
Analgesic Therapy ◽  
Acute Pain Therapy ◽  
Inflammatory Drugs ◽  
The Individual ◽  
Key Aspects

The personalization of therapy is one of the innovative approaches gaining an increasingly strong foothold in modern medicine, implying an individual approach to each patient, taking into account the individual characteristics of the patient and the specific clinical case. This same standpoint of personified therapy should be used to plan rational analgesic therapy, the most important component of managing patients with the most common and socially significant diseases, with conditions that have a significant impact on the patient’s quality of life and worsen the course of concomitant diseases. The Meeting of Experts of different specialties such as rheumatologists, neurologists, cardiologists and clinical pharmacologists considered the key aspects of the prescription of NSAIDs, the most widely used class of painkillers, including those used for the relief of musculoskeletal pain. It was noted that when choosing NSAIDs, the practitioner should take into account the diagnosis, the planned duration of  analgesic therapy, the intensity of pain, medical history data, the presence of comorbid diseases and risk factors for drug complications. There are different types of NSAIDs, some of which are most useful for urgent acute pain therapy (eg, ketoprofen), while others are most suitable for long-term pain management in chronic diseases (eg, etoricoxib). In any case, the practitioner should take into account the priority of patient safety and pay the utmost attention to the prevention of NSAIDassociated complications, and also keep in mind the duration of the specific drug administration permitted by the patient information leaflet. It was also noted that the launch of a new generic etoricoxib (Kostarox®) expands the possibilities of analgesic therapy for the Russian practitioners.

Sign in / Sign up

Export Citation Format

Share Document