scholarly journals Personalization of the use of non-steroidal anti-inflammatory drugs for musculoskeletal diseases. Resolution on the results of the Meeting of Experts of December 13, 2017

2018 ◽  
pp. 76-84 ◽  
Author(s):  
A. E. Karateev ◽  
A. M. Lila ◽  
I. S. Dydykina ◽  
P. R. Kamchatnov ◽  
S. O. Mazurenko ◽  
...  
Keyword(s):  
Musculoskeletal Diseases ◽  
Modern Medicine ◽  
Individual Characteristics ◽  
Analgesic Therapy ◽  
Acute Pain Therapy ◽  
Inflammatory Drugs ◽  
The Individual ◽  
Key Aspects

The personalization of therapy is one of the innovative approaches gaining an increasingly strong foothold in modern medicine, implying an individual approach to each patient, taking into account the individual characteristics of the patient and the specific clinical case. This same standpoint of personified therapy should be used to plan rational analgesic therapy, the most important component of managing patients with the most common and socially significant diseases, with conditions that have a significant impact on the patient’s quality of life and worsen the course of concomitant diseases. The Meeting of Experts of different specialties such as rheumatologists, neurologists, cardiologists and clinical pharmacologists considered the key aspects of the prescription of NSAIDs, the most widely used class of painkillers, including those used for the relief of musculoskeletal pain. It was noted that when choosing NSAIDs, the practitioner should take into account the diagnosis, the planned duration of  analgesic therapy, the intensity of pain, medical history data, the presence of comorbid diseases and risk factors for drug complications. There are different types of NSAIDs, some of which are most useful for urgent acute pain therapy (eg, ketoprofen), while others are most suitable for long-term pain management in chronic diseases (eg, etoricoxib). In any case, the practitioner should take into account the priority of patient safety and pay the utmost attention to the prevention of NSAIDassociated complications, and also keep in mind the duration of the specific drug administration permitted by the patient information leaflet. It was also noted that the launch of a new generic etoricoxib (Kostarox®) expands the possibilities of analgesic therapy for the Russian practitioners.

scholarly journals DIETETICS MANAGEMENT IN UDAVARTINI YONIVYAPAD (DYSMENORRHEA): A REVIEW

2021 ◽  
Vol 12 (5) ◽  
pp. 60-62
Author(s):  
Swati Bhandari ◽  
Divya Badwal ◽  
Ruby Rani Agarwal
Keyword(s):  
Medical Condition ◽  
Modern Medicine ◽  
Poor Quality ◽  
Anxiety And Depression ◽  
Clinical Feature ◽  
Negative Effects ◽  
Inflammatory Drugs

Dysmenorrhea is a medical condition characterized by severe uterine pain during menstruation. It is one of the most common gynaecological complaints observed. It has a high impact on women’s quality of life resulting in a restriction of daily activities, a lower academic performance, and poor quality of sleep and has negative effects on mood, causing anxiety and depression. Dysmenorrhea is explained as an Udavartini Yonivyapad in Ayurveda. The main clinical feature of Udavartini is rajahkricchrata i.e., painful menstruation. Today’s stressful modern lifestyle and faulty food habits i.e., increased consumption of oily and junk food is leading to a higher incidence of dysmenorrhea. In modern medicine, dysmenorrhea is treated by oral hormonal pills, non-steroidal anti-inflammatory drugs, and analgesics. Long term use of these produces side effects. Thus, these are not the solution to the problem. The role of diet has been well considered as an etiological factor responsible for causing dysmenorrhea. Ayurveda has given importance to diet and regimen as a part of Chikitsa. Thus, taking an appropriate diet (Pathya Ahara) and avoiding a faulty diet (Apathya Ahara) will help in prevention as well as reducing the symptoms of dysmenorrhea.

Possibilities and prospects of conservative therapy for endometriosis, as a chronical progressing disease (review of literature)

GYNECOLOGY ◽  
2020 ◽  
Vol 22 (1) ◽  
pp. 14-18 ◽  
Author(s):  
Tatyana Yu. Pestrikova ◽  
Elena A. Yurasova ◽  
Igor V. Yurasov
Keyword(s):  
Quality Of Life ◽  
Abnormal Uterine Bleeding ◽  
Modern Medicine ◽  
Reproductive Age ◽  
Aim Analysis ◽  
Scientific Publications ◽  
Terra Incognita ◽  
Positive Effect

Relevance. Endometriosis is a common gynecological disease that affects up to 10% of women of reproductive age worldwide and is the main cause of pain and infertility. Endometriosis is a disease, although it has been known for a long time, nevertheless, in many ways it represents terra incognita for modern medicine. Aim. Analysis of literature on the feasibility of long-term and the use of the drug dienogest 2 mg (Vizanne), which has a positive effect on the quality of life of patients with endometriosis. Materials and methods. To write this review, a search was made for domestic and foreign publications in Russian and international search engines (PubMed, eLibrary, etc.) over the past 13 years. The review included articles from peer-reviewed literature. Results. The review presents data on the difficulties of verifying the diagnosis of endometriosis due to a combination of this pathology with pain, infertility, abnormal uterine bleeding. The pathogenesis of the origin of endometriosis-associated pain is presented. The efficacy of the use of the drug dienogest (Vizanne), which has a powerful antiproliferative effect that reduces the main symptoms of endometriosis (pain, bleeding), is substantiated. The expediency of long-term and safe use of the drug dienogest (Vizanne), which has a positive effect on the quality of life of patients with endometriosis, has been proved. Conclusions. Numerous scientific publications confirm the feasibility of prolonged use of the drug dienogest (Vizanne), to achieve remission during endometriosis.

scholarly journals Promoting Sustainable Mobility: A Perspective from Car and Public Transport Users

2021 ◽  
Vol 18 (9) ◽  
pp. 4715
Author(s):  
Audrius Dėdelė ◽  
Auksė Miškinytė
Keyword(s):  
Public Transport ◽  
Adult Population ◽  
Individual Characteristics ◽  
Urban Mobility ◽  
Sustainable Mobility ◽  
Bicycle Safety ◽  
Key Factor ◽  
The Individual ◽  
Significant Factors

Sustainable mobility is becoming a key factor in improving the quality of life of the residents and increasing physical activity (PA) levels. The current situation of sustainable mobility and its analysis is a first step in understanding the factors that would encourage residents to discover and choose alternative modes of travel. The present study examined the factors that encourage the choice of active modes of travel among urban adult population. Walking and cycling were analyzed as the most sustainable forms of urban mobility from the perspective of car and public transport (PT) users. Total of 902 subjects aged 18 years or older were analyzed in the study to assess commuting habits in Kaunas city, Lithuania. The majority (61.1%) of the respondents used a passenger vehicle, 28.2% used PT, and only 13.5% used active modes of travel. The results showed that safer pedestrian crossings, and comfortable paths were the most significant factors that encourage walking. A wider cycling network, and bicycle safety were the most important incentives for the promotion of cycling. Our findings show that the main factors encouraging walking and cycling among car and PT users are similar, however, the individual characteristics that determine the choice of these factors vary significantly.

P2Y12 inhibitors for the neurointerventionalist

2021 ◽  
pp. 159101992110150
Author(s):  
Robin J Borchert ◽  
Davide Simonato ◽  
Charlotte R Hickman ◽  
Maurizio Fuschi ◽  
Lucie Thibault ◽  
...  
Keyword(s):  
Mechanical Thrombectomy ◽  
Antiplatelet Agent ◽  
Antiplatelet Agents ◽  
Individual Characteristics ◽  
Onset Of Action ◽  
P2y12 Inhibitors ◽  
Hemorrhagic Complications ◽  
The Individual ◽  
Neurointerventional Procedures

The use of antiplatelets is widespread in clinical practice. However, for neurointerventional procedures, protocols for antiplatelet use are scarce and practice varies between individuals and institutions. This is further complicated by the quantity of antiplatelet agents which differ in route of administration, dosage, onset of action, efficacy and ischemic and hemorrhagic complications. Clarifying the individual characteristics for each antiplatelet agent, and their associated risks, will increasingly become relevant as the practice of mechanical thrombectomy, stenting, coiling and flow diversion procedures grows. The aim of this review is to summarize the existing literature for the use of P2Y12 inhibitors in neurointerventional procedures, examine the quality of the evidence, and highlight areas in need of further research.

Mandible: evaluation of its morphology, aging process and sexual dimorphism for aesthetic treatment purpose

2021 ◽  
Vol 5 (3) ◽  
pp. 42-46
Author(s):  
Luiz Eduardo Toledo Avelar
Keyword(s):  
Sexual Dimorphism ◽  
Bone Structure ◽  
Individual Characteristics ◽  
Mandibular Angle ◽  
Fractional Analysis ◽  
The Face ◽  
The Individual ◽  
Dynamic Quality ◽  
Base Of The Skull

The mandible is the most important bone structure of the facial makeup. Its morphology differs with respect to genetic factors, sexual dimorphism, and age. Among its particular characteristics is the ability to adapt with its counterpart, the base of the skull, conferring a dynamic quality of this bone, by the mechanism of constant remodeling. In order to understand the involvement of the mandible in the evaluation of the lower third of the face, a fractional analysis of its parts is necessary considering morphological parameters of the mandibular angle. The purpose of this study is to demonstrate the importance of the mandible as an instrument in the analysis of the lower third of the face, allowing the accomplishment of aesthetic treatment, respecting the individual characteristics.

Neurotechnology as a factor of the educational process transformation

2021 ◽  
pp. 98-13
Author(s):  
Л.Д. Александрова ◽  
Р.А. Богачева ◽  
Т.А. Чекалина ◽  
М.В. Максимова ◽  
В.И. Тимонина
Keyword(s):  
Effective Means ◽  
Individual Characteristics ◽  
Educational Process ◽  
Special Equipment ◽  
Research Areas ◽  
Long Time ◽  
Mental Abilities ◽  
The Individual ◽  
And Control

Изучение возможностей мозга для повышения качества обучения находится в центре внимания педагогической науки уже много лет. Развитие цифровизации позволило использовать в исследованиях специальное оборудование, с помощью которого можно оценивать и контролировать работу мозга, развивать умственные способности, познавательные функции и т. п. Нейротехнологии стали эффективным средством, позволяющим трансформировать образовательный процесс за счет подбора специального учебного контента с учетом индивидуальных особенностей обучающихся. Вместе с тем возникает необходимость в конкретизации терминологии и определении актуальных направлений исследований в данной области. For a long time, the study of the brain capabilities for the improvement of the quality of education has been an urgent direction in pedagogical science. Due to the development of digitalization, new areas of research have emerged related to the use of special equipment that makes it possible to assess and control brainwork, develop mental abilities, cognitive functions, etc. One of them is neurotechnology, which is an effective means of transforming the educational process: it offers educational content based on the individual characteristics of students. Thus, a need to concretize the terminology and determine the current research areas arises. The article aims to attempt to fill this gap with the help of a representative analysis of publications on neurotechnologies, as well as the essence of neuroeducation.

scholarly journals Les joueurs sans problème de jeu de 55 ans et plus : événements, conséquences et caractéristiques structurelles et environnementales influençant les habitudes de jeu

2016 ◽  
pp. 89
Author(s):  
Isabelle Giroux ◽  
Francine Ferland ◽  
Cathy Savard ◽  
Christian Jacques ◽  
Priscilla Brochu ◽  
...  
Keyword(s):  
Content Analysis ◽  
Focus Groups ◽  
Life Events ◽  
Psychological Health ◽  
Qualitative Content Analysis ◽  
Individual Characteristics ◽  
Gambling Problems ◽  
Negative Consequences ◽  
The Individual

Gambling habits of people aged 55 years and over without gambling problems are rarely being investigated. In order to document life events and to identify the impacts of gambling on quality of life, 19 participants aged 55 to 74 years without gambling problems, male and female, were assembled in three focus groups. Qualitative content analysis of the groups reveals changes in gambling habits associated with transition to retirement and occurrence of health problems. The content analysis further reveals a variety of positive and negative consequences of gambling habits on finances, hobbies, social relationships, and psychological health. Although the focus groups did not target the structural or environmental characteristics of gambling that influence participants' gambling habits, those themes were brought up spontaneously. Results highlight the necessity to study life events from a larger perspective including, for example, protective and risk factors, in order to better understand the life contexts and the individual characteristics that may lead to an alteration or not of gambling habits.

scholarly journals Relationship between Symptoms in Women with Endometriosis and Lifestyles: a Qualitative Interview Study

2020 ◽  
Vol 4 (4) ◽  
pp. 178-183
Author(s):  
M. Scavone ◽  
C. Gizzi ◽  
E. Albi
Keyword(s):  
Physical Activity ◽  
Uterine Cavity ◽  
Individual Characteristics ◽  
The Body ◽  
Quality Of Sleep ◽  
Qualitative Interview Study ◽  
Italian Women ◽  
The Individual ◽  
Reproductive Aged Women

AbstractEndometriosis is a common condition that affects reproductive-aged women and is characterized by the presence of endo-metrial tissue outside the uterine cavity with nodules and lesions. The study aimed to analyze lifestyles of women affected by endometriosis in relation with their symptoms. In this observational study, 735 Italian women have been interviewed online through a questionnaire structured in two parts. The first part was mainly anamnestic, focused on gathering information about the age, the stage of disease, comorbidities, involved organs, symptomatology, chirurgical treatment, induced menopause. The second part focused on the individual characteristics and lifestyle of the patients such as the body mass index, physical activity, quality of sleep, and the diet. The results showed how a healthy diet and a regular physical activity reduce drastically the symptoms of the patients.

scholarly journals USE BY CADETS OF A MILITARY UNIVERSITY OF AN ELECTRONIC TEXTBOOK IN THE PROCESS OF STUDYING PHYSICS

2020 ◽  
pp. 94-101
Author(s):  
I.B. Nikolaeva ◽  
Keyword(s):  
Military Service ◽  
Individual Characteristics ◽  
Electronic Textbooks ◽  
Distinctive Features ◽  
Electronic Textbook ◽  
Paper Version ◽  
Materials Modeling ◽  
Dynamic Form ◽  
The Individual

The article reveals the features of the use by cadets of a military university of an electronic textbook in the process of studying physics. The relevance of using an electronic textbook in a military university is due to the need to adapt as much as possible to specific general educational and professionally oriented disciplines, increase the activity and motivation of cadets, and strengthen the mastery of educational material. In this study, the electronic textbook is presented as a component of the electronic textbook, which completely replaces or complements the paper version. The author highlighted the distinctive features of the electronic textbook: interactivity, focus on several channels of perception, taking into account the individual characteristics of students, using different ways of presenting information in a dynamic form with links and additional materials, modeling and visualization, activating students' motivation, a combination of theoretical and practical material, opportunities automatic knowledge control. Since training at a military university is related to military service in secrecy, the use of electronic textbooks allows not only to cover the entire cadet staff, improve the quality of training, increase student activity, but also ensure the relevance of training and practical material.

scholarly journals UNPREPARED READING AS A TYPE OF SPONTANEOUS SPEECH (on Signs of Spontaneity in Reading in a Non-Native Language)

2021 ◽  
Vol 13 (2) ◽  
pp. 36-46
Author(s):  
Сhunxia Kong ◽  
Keyword(s):  
Native Language ◽  
Spontaneous Speech ◽  
Individual Characteristics ◽  
Speech Sounds ◽  
Source Text ◽  
Speech Corpus ◽  
Integral Characteristics ◽  
The Individual ◽  
Whole Word

The article discusses unprepared reading in a non-native language and shows it to have all the signs of spontaneity that are traditionally considered integral characteristics of any spontaneous speech: hesitation pauses, both physical (ɭ) and filled with non-speech sounds (uh, m-m), word breaks, reading the whole word or part of it by syllables, vocalization of a consonant, and so forth. The material for the analysis included 40 monologues of reading the story by M. Zoshchenko Fantasy Shirt and a non-plot excerpt from V. Korolenko’s story The Blind Musician recorded from 20 Chinese informants. All the monologues are included in the block of Russian interfering speech of the Chinese as part of the monologic speech corpus Ba­lanced Annotated Text Library. As the analysis showed, it is more often that there is not one sign of spontaneity but a whole complex of such signs, and together they fill hesitation pauses, help the speaker to control the quality of speech or correct what was said, etc. In addition, the occurrence of various signs of spontaneity in the course of unprepared reading is closely related to the individual characteristics of the speaker/reader. In general, we have found that there are more signs of spontaneity in the speech of men (3,244 cases; 40.7 %) than in the speech of women (2,049; 27.7 %), in the speech of informants with a lower level of proficiency in Russian B2 (2,993; 37.9 %) than in the speech of informants with a higher level C1 (2,300; 30.8 %), in the speech of extroverts (1,521; 38 %) than in the speech of ambiverts (1,694; 35,2 %) and introverts (2,078; 31,7 %). As to the type of the source text, there turned out to be more signs of spontaneity in monologues of reading a plot text than in monologues of reading a non-plot text (3,031; 40.3 vs 2,283; 31 %). The paper concludes that reading should be recognized as a spontaneous type of speech activity.

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