scholarly journals PREVALENCE OF GROUP B STREPTOCOCCUS AND LEVEL OF RELIGIOSITY OF JEWISH MOTHERS IN NORTHERN ISRAEL - IS THERE A CONNECTION?

2021 ◽  
Vol 13 (1) ◽  
pp. 9-17
Author(s):  
Adi SHARABI-NOV ◽  
Stefan COJOCARU
Keyword(s):  
Pregnant Women ◽  
Medical Center ◽  
Health Maintenance Organization ◽  
Group B Streptococcus ◽  
Delivery Room ◽  
Cross Sectional ◽  
Health Maintenance ◽  
Increased Risk ◽  
Geographical Regions ◽  
Group B

Group B streptococcus (GBS) during pregnancy is associated with increased risk of preterm delivery and is a leading cause of invasive infections in newborns. Rates of vaginal GBS prevalence in pregnant women vary among ethnic groups and geographical regions, with a range of 0.5-38%. The aim is to assess the prevalence rate of GBS bacteria among Jewish pregnant mothers in northern Israel, according to their level of religiosity. A cross-sectional study was pursued in 303 Jewish mothers at Ziv Medical Center, Safed of whom 89 (29.4%) were secular, 59 (19.5%) traditional, 60 (19.8%) Orthodox and 95 (31.3%) ultra-Orthodox, from December 2019-July 2020. All participants were tested for GBS from pregnancy week 35 as part of the routine medical care at their Health Maintenance Organization (HMO) and submitted the GBS test result upon arrival at the hospital delivery room. The overall prevalence of GBS was 33.7%: 16.9% of the secular mothers, 25.4% of the traditional women and 46.5% of the Orthodox and ultra-Orthodox group (p<0.001). In a univariate regression model the risk of GBS carriage in Orthodox mothers was 2.5 times higher and 6 times higher in ultra-Orthodox mothers than in secular mothers (p for trend <0.001). The prevalence of GBS was directly and significantly associated with the level of the birthing mother's religiosity. This study shows the need for systematic GBS screening of all pregnant women, particularly of Orthodox and ultra-Orthodox women, prior to their arrival in the delivery room.

scholarly journals Poor Adherence to the Screening-Based Strategy of Group B Streptococcus Despite Colonization of Pregnant Women in Greece

Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 418
Author(s):  
Maria Maroudia Berikopoulou ◽  
Aikaterini Pana ◽  
Theodota Liakopoulou-Tsitsipi ◽  
Nikos F. Vlahos ◽  
Vasiliki Papaevangelou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Pregnant Women ◽  
Late Onset ◽  
Group B Streptococcus ◽  
Culture Collection ◽  
Carrier Status ◽  
Cross Sectional ◽  
Screening Guidelines ◽  
Group B

Group B streptococcus (GBS) is a leading cause of serious neonatal infections. Maternal GBS colonization is associated with early- and late-onset neonatal disease (EOD/LOD). In Greece, a screening-based strategy is recommended, in which concurrent vaginal-rectal cultures should be obtained between 36 0/7 and 37 6/7 weeks’ gestation. We sought to examine the level of adherence to the GBS screening guidelines and estimate the prevalence of GBS colonization among pregnant women. Although in Greece the screening-based strategy is followed, we also examined known EOD risk factors and linked them to GBS colonization. A cross-sectional study of 604 women postpartum in three hospitals and maternity clinics was conducted. Following written informed consent, data were collected via a short self-completed questionnaire and review of patients’ records. In 34.6% of the enrolled pregnant women, no culture had been taken. Of the remaining, 12.8% had proper vaginal-rectal sample collections. The overall maternal colonization rate was 9.6%. At least one risk factor for EOD was identified in 12.6% of participants. The presence of risk factors was associated with positive cultures (p = 0.014). The rate of culture collection did not differ between women with or without an EOD risk factor. Adherence to a universal screening of pregnant women with vaginal-rectal cultures was poor. Despite probable underestimation of GBS carrier status, almost 1 in 10 participants were GBS positive during pregnancy. Screening of women with risk factors for EOD should, at least, be prioritized to achieve prevention and prompt intervention of EOD.

scholarly journals Prevalence and Serotype Determination of Streptococcus agalactiae Isolated From Non-Pregnant Women in Tehran, Iran

2020 ◽  
Author(s):  
Leila Goudarzi ◽  
Mohammad Bagher Khalili ◽  
Mahmood Vakili ◽  
Maryam Sadeh
Keyword(s):  
Pregnant Women ◽  
Streptococcus Agalactiae ◽  
Group B Streptococcus ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Specific Pcr ◽  
Pcr Method ◽  
Group B ◽  
Tehran Area

Consequence of Streptococcus agalactiae, Group B Streptococcus (GBS) relating infant’s diseases are well documented. Although many women carry this bacterium in their vagina, they may transfer to their infant during delivery and may result in different neonatal invasive diseases. The aim of this study was to determine the prevalence of GBS and serotyping the isolated species among un-selective non-pregnant women who attended two gynecology clinics in Tehran. In this cross-sectional study, a total of 560 vaginal samples collected from non-pregnant women. Following inoculation of the specimen on Blood Agar, the standard technology was applied for the final identification of GBS. Detected GBS species were further confirmed using specific PCR directed on dlts gene. Capsular serotyping was done by using the multiplex PCR method. The chi-square method was used for statistical analysis. Fifty (8.9%) out of 560 non-pregnant women were carriers of GBS. The most common types were III (36%), followed by type II (32%), Ia (26%), and Ib (6%), respectively. Results represent that the prevalence rate of GBS in non-pregnant women was reliable and similar to what obtained from pregnant women. In addition, the serotype III was found the most dominant types, as well as other investigations in the Tehran area. Therefore, vaccine designation based on type III is recommended.

scholarly journals Knowledge, attitude and current practices of pregnant women towards group B streptococcus screening: cross-sectional study, Al-Madinah, Saudi Arabia

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e032487
Author(s):  
Amer Alshengeti ◽  
Amjad Alharbi ◽  
Shahad Alraddadi ◽  
Abdulsalam Alawfi ◽  
Bushra Aljohani
Keyword(s):  
Saudi Arabia ◽  
Pregnant Women ◽  
Group B Streptococcus ◽  
Knowledge Score ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Screening Strategies ◽  
Group B ◽  
Universal Culture

AimsGroup B streptococcus (GBS) is one of the most frequent bacterial pathogens causing invasive infections in neonates. It can be transmitted from colonised mother to neonates around delivery. Screening strategies for GBS during pregnancy include either universal culture-based or risk-based screening. The present study aimed to assess the knowledge, attitude and current practices of pregnant women towards GBS screening in Al-Madinah City, Saudi Arabia.MethodsA hospital-based cross-sectional study was conducted at Madinah Maternity and Children Hospital, Al-Madinah, Saudi Arabia, from May to July 2018. Participants were recruited from postnatal wards. Participants were interviewed using a previously published validated survey that was divided into the following domains: demographic data, knowledge, experience and attitude towards different GBS screening strategies.ResultsA total of 377 out of 450 women (response rate 83.7%) were enrolled. The results showed that the overall mean knowledge score of the pregnant women towards GBS screening was 59.8%. Majority of the women (66.8%) were not aware of the GBS bacterium, while 86.5% of them had never been informed of GBS risk assessment during their pregnancies. The mean knowledge score among women who were aware of GBS (62.8%) was significantly higher than that among women who were not (58.4%) (p=0.015). However, majority of the pregnant women (61.8%) showed preference for universal culture-based GBS screening strategy over risk-based strategy.ConclusionThe study results have concluded that the level of awareness and knowledge about GBS among pregnant women were relatively poor; however, majority of the pregnant women prefer universal culture-based screening.

scholarly journals Group B Streptococcus Colonization among Pregnant Women Attending Antenatal Care at Tertiary Hospital in Rural Southwestern Uganda

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Abdul Namugongo ◽  
Joel Bazira ◽  
Yarine Fajardot ◽  
Ngonzi Joseph
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Univariate Analysis ◽  
Group B Streptococcus ◽  
Antenatal Clinic ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Group B ◽  
Southwestern Uganda

Objectives.This study sought to determine the prevalence and factors associated with group B streptococcal anogenital colonization among pregnant women attending antenatal care at Mbarara Regional Referral Hospital, a tertiary hospital.Methods.Cross-sectional study where 309 pregnant women ≥ thirty-five weeks of gestation attending antenatal clinic were consecutively recruited between January and March 2015. Anovaginal swabs were collected and tested qualitatively using rapid visual immunoassay GBS test kits for presence of GBS antigens. Data was analyzed using STATA version 12. In univariate analysis, GBS colonized mothers were presented as percentages and numbers, and in multivariate analysis logistic regression analysis was applied to determine the associations of exposure variable and GBS colonization; a value of less than 0.05 was considered significant.Results.Mothers’ median age was 25 years, 14.6% mothers being obese. GBS prevalence was 28.8%, 95% CI: 23.7–33.9. Obesity was the only significant factor associated with anogenital GBS colonization with odds ratio of 3.78, 95% CI: 1.78–8.35, apvalue of 0.001. Maternal ages, educational level, residence, and gravidity were not associated with GBS anogenital colonization.Conclusion.Group B streptococcal anogenital colonization among pregnant women attending antenatal care at tertiary hospital, in Southwestern Uganda, is high.

scholarly journals Group B Streptococcus Colonization in Pregnancy: Prevalence, Determinants and Antibacterial Susceptibility Pattern in Sagamu, Nigeria

2019 ◽  
pp. 1-8
Author(s):  
Adebayo A. Akadri ◽  
Bamidele D. Osuolale ◽  
Tessie O. Shorunmu ◽  
Oluwaseyi I. Odelola
Keyword(s):  
Pregnant Women ◽  
Group B Streptococcus ◽  
Antenatal Clinic ◽  
Cross Sectional Study ◽  
University Teaching ◽  
Binary Logistic Regression Analysis ◽  
Susceptibility Pattern ◽  
Cross Sectional ◽  
Ogun State ◽  
Group B

Aims: To establish the prevalence, determinants and the antibiotic susceptibility pattern of Group B streptococcus in pregnant women in Sagamu, Ogun State, Nigeria. Study Design: Prospective cross-sectional study Place and Duration of Study: The study was carried out at the antenatal clinic at Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria, between July 2017 and December 2017. Methodology: The study involved 184 pregnant women attending antenatal clinic. Lower vaginal and rectal swabs were collected under aseptic condition and immediately sent to the laboratory for processing. The samples were assayed for the presence of group B streptococcus using conventional methods. Information on the socio demographic characteristics and details of delivery were recorded on a data capture sheet. Results: The prevalence of Group B streptococcus was 27.7%. The odds of Group B streptococcus colonization was significantly higher among women of low parity (≤ 2) and binary logistic regression analysis showed that parity was predictive of Group B streptococcus colonization (OR 3.7; 95% CI = 1.03-13.46; P=.045). Younger women (age ≤ 30 years) and women carrying term pregnancies had a non significant trend towards higher odds of Group B streptococcus colonization [(OR= 1.22, 95% CI: 0.6-2.3, P = .54) and (OR=1.6, CI: 0.8-3.2; P = .15) respectively]. The resistance of group B streptococcus isolates to penicillin and ampicillin was 39.2% and 37.3% respectively.                           Conclusion: The group B streptococcus colonization rate in this study is high. Factors such as low parity, young maternal age and term pregnancies are associated with increased odds of colonization. The emergence of resistance to the commonly prescribed antibiotics calls for re-evaluation of the current recommendations regarding the antibiotics prophylaxis.

scholarly journals Group B Streptococcus Colonisation, Prevalence, Associated Risk Factors and Antimicrobial Susceptibility Pattern Among Pregnant Women Attending Antenatal Care at Dschang District Hospital, West Region of Cameroun: A hospital-based Cross Sectional Study

2021 ◽  
Author(s):  
Leonard Sama ◽  
michel Noubom ◽  
Christelle KENNE ◽  
Thibau Tchouangueu ◽  
omer Ngouateu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
District Hospital ◽  
Group B Streptococcus ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Group B ◽  
Associated Risk Factors

Background: Group B streptococcus (GBS), also name as Streptococcus agalactiae, is a gram-positive bacterium know for it capacity to colonises the vaginal and rectal areas of the mother and is a leading cause of neonatal mortality and morbidity. This study aimed at determining the prevalence, associated risk factors and antimicrobial susceptibility of GBS colonization among pregnant women attending antenatal care at Dschang District Hospital. Methods: This hospital-base cross-sectional study targeted pregnant women population attending hospitals for routine prenatal testing using a multistage sampling method. Pregnant women at 23.46 ± 6.44 weeks gestation completed a questionnaire and vaginal swabs were obtained for GBS analysis. Data were analysed using chi-squared (χ2) test or the Fisher’s exact test when appropriate and the multivariable logistic regression models. Results: The colonisation rate of GBS among pregnant women was 8.69%. Induce abortion (odds ratio [CI] = 3.09, 95% [1.56-6.21]), Spontaneaous abortions (OR= 2.82, 95% CI 1.14-7.29), Stillborn (OR [CI] = 7.75, 95% [2.61-21.71]), Fever (OR [CI] = 0.37, 95% [0.19-0.71]) and anemia (OR [CI] = 0.22, 95% [0.12-0.43]) were found to be influencing factors associated with GBS colonisation. Conclusion: Our findings suggest that none of the studied factors were significantly associated with GBS colonisation. Further longitudinal research is needed to establish the causal relationship and its biological mechanisms. Keys words: Group B Streptococcus, Prevalence, Risk Factors, Antimicrobial Susceptibility, Pregnant Women

scholarly journals Group B Streptococci Colonization in Pregnant Guatemalan Women: Prevalence, Risk Factors, and Vaginal Microbiome

2017 ◽  
Vol 4 (1) ◽  
Author(s):  
Anne-Marie Rick ◽  
Angie Aguilar ◽  
Rosita Cortes ◽  
Remei Gordillo ◽  
Mario Melgar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Low Income ◽  
Group B Streptococcus ◽  
Cross Sectional Study ◽  
Low Income Countries ◽  
Vaginal Microbiome ◽  
Group B Streptococci ◽  
Cross Sectional ◽  
Group B

Abstract Background Infection causes 1 of every 5 neonatal deaths globally. Group B Streptococcus (GBS) is the most significant pathogen, although little is known about its epidemiology and risk in low-income countries. Methods A cross-sectional study in 2015 at a public hospital in Guatemala City enrolled women ≥35 weeks’ gestation. Vaginal and rectal swabs were processed using Lim broth and GBS CHROMagar then agglutination testing. Risk factors were assessed using multivariate analysis. Vaginal microbiota were profiled by 16S ribosomal ribonucleic acid sequencing in a subset of 94 women. Results Of 896 pregnant women, 155 (17.3%; 95% confidence interval [CI], 14.9–19.9) were GBS colonized. Colonization was associated with history of previous infant with poor outcome (odds ratio [OR], 1.94; 95% CI, 1.15–3.27) and increasing maternal age (OR, 1.05; 95% CI, 1.02–1.09). Multiparity was protective (OR, .39; 95% CI, .21–.72). Four (6%) GBS-exposed infants had early-onset neonatal sepsis. Vaginal microbiome composition was associated with previous antibiotic exposure (P = .003) and previous low birth weight infant (P = .03), but not GBS colonization (P = .72). Several individual taxa differed in abundance between colonized and noncolonized women. Conclusions Group B Streptococcus is prevalent in pregnant women from Guatemala with different risk factors than previously described. Although the vaginal microbiome was not altered significantly in GBS-colonized women, use of antibiotics had an effect on its composition.

scholarly journals Evaluation of the Results of Group B Streptococcus Screening by MALDI-TOF MS among Pregnant Women in a Hungarian Hospital

Pathogens ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 1 ◽  
Author(s):  
Marianna Ábrók ◽  
Petra Tigyi ◽  
Markus Kostrzewa ◽  
Katalin Burián ◽  
Judit Deák
Keyword(s):  
Pregnant Women ◽  
Group B Streptococcus ◽  
Premature Delivery ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Increased Risk ◽  
High Prevalence ◽  
Resistant Strains ◽  
Group B ◽  
Tof Ms

Pregnant women colonized by Streptococcus agalactiae, or group B streptococcus (GBS), are at an increased risk of premature delivery and stillbirth, and their neonates can be endangered by the development of an invasive GBS disease. In this study, the results of the GBS screening among pregnant women performed between 2012 and 2018 (n = 19267) are presented. For the GBS positive samples, the antibiotic susceptibility of the isolated strains was also tested (n = 3554). During the examined period, the colonization rate varied between 17.4% and 19.8%. The overall rate of erythromycin and clindamycin resistance in the GBS positive samples was 34.9% and 34.6%, respectively. The frequency of the erythromycin and clindamycin resistant strains showed an increasing tendency. An analysis of the MALDI-TOF MS spectra of 260 GBS isolates revealed that 46.5% of them belonged to either the ST-1 or the ST-17 sequence types, indicating a high prevalence of these potentially invasive GBS strains in our region. More than half of the strains identified as ST-1 (52.1%) proved to be resistant to erythromycin and clindamycin.

scholarly journals PROFILE OF PREGNANT WOMEN COLONIZED BY GROUP B Streptococcus SERVED BY THE UNIQUE HEALTH SYSTEM IN A LABORATORY OF MEDIANEIRA / PARANÁ

2021 ◽  
pp. 38
Author(s):  
Keyword(s):  
Health System ◽  
Pregnant Women ◽  
Skin Color ◽  
Group B Streptococcus ◽  
Positive Culture ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Unified Health System ◽  
Vaginal Swabs ◽  
Group B

Objective: The objective of this study was to determine the prevalence of pregnant colonization by group B Streptococcus (GBS) and to verify whether socioeconomic and demographic conditions are risk factors for colonization by this bacterium. Method: This cross-sectional study included the collection of sociodemographic data through a questionnaire and authorization to access the result of the cultivation of vaginal swabs for the investigation of GBS of 50 women treated at the Unified Health System (SUS) in a laboratory in the municipality of Medianeira, PR, between august and september 2020. Results: The population studied showed a 14% prevalence of colonization by GBS, within national and world standards. Among the factors analyzed, the only significant and protective association was living with fewer people in the same house, up to two people, reducing the risk of developing a positive culture for GBS by more than 5 times (5.54) when compared to pregnant women who live with more than 3 people in the same residence (p <0.1; RR = 0.181, CI 90% 0.04-0.82). There was no association between colonization by GBS with age, skin color, school education, occupation and type of housing, income, fixed partner, parity and gestational symptoms. Conclusion: This study requires greater sampling for statistical strengthening, however it indicates basic data for the creation of GBS disease prevention protocols based on the applied community.

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