scholarly journals Role of cranberry juice in prevention of dental caries and periodontal disease`

2019 ◽  
Author(s):  
Sana Farista ◽  
Akhilesh Jakhete ◽  
Shanin Farista
Keyword(s):  
Dental Caries ◽  
Adverse Effects ◽  
Periodontal Disease ◽  
Dental Plaque ◽  
Oral Diseases ◽  
Cranberry Juice ◽  
Limited Success ◽  
The Many ◽  
Potential Use

Dental caries and Periodontal Disease (periodontitis) are the most common oral diseases. The aetiology of both these diseases can be traced back to the microorganisms in the dental plaque. Over the years numerous anti plaque agents have been developed with limited success and varying degrees of adverse effects. The current research is in the direction of using plant or herbal based products as anti-plaque agent. Out of the many agents studied, cranberry (Vacciniummacrocarpon) has shown maximum potential for use as anti-plaque agent. The current paper aims to review the existing literature on cranberry and its potential use in dentistry in minimizing the prevalence of dental caries and periodontal disease. KEY WORDS: Cranberry Juice, Anti Plaque Agent, Periodontitis, Non Dialyzable Material

scholarly journals Oral Health Literacy and Oral Health Status among Undergraduate University Students

2021 ◽  
Vol 6 (2) ◽  
pp. 13-22
Author(s):  
Azlan Jaafar ◽  
Normaliza AB Malik ◽  
aws hashim ali alkadhim
Keyword(s):  
Health Status ◽  
Oral Health ◽  
Health Literacy ◽  
Dental Caries ◽  
Periodontal Disease ◽  
Undergraduate Students ◽  
Dental Plaque ◽  
Oral Health Status ◽  
Weak Correlation ◽  
Oral Health Literacy

Objective: To identify the prevalence of caries, plaque score, and periodontal disease and explore the correlations between oral health literacy scores and oral health status among undergraduate students. Materials and Methods: A cross-sectional study was conducted with a group of undergraduate students using the Malay version of the Oral Health Literacy (OHL) Index. A stratified random sampling technique was used to select the samples. Clinical oral examinations were conducted by a single trained examiner using a Community Periodontal Index (CPI) probe and a mouth mirror. Data analysis was conducted using statistical tests contained in SPSS version 26, and statistical significance was set at p<0.05. Results: A total of 280 students were recruited into the study. The prevalence of caries and periodontal disease was 58.9 and 13.2%, respectively. There was a significant association between OHL and field of study (p<0.001). There was also a significant negative but weak correlation between OHL and dental plaque scores (r= -0.147; p=0.014). A significant positive but weak correlation was found between dental plaque scores and dental caries (r= 0.135; p=0.024) and periodontal pocket depth (r= 0.168; p=0.005). Conclusion: The prevalence of dental caries was high, while the prevalence of periodontal diseases was low in this study. OHL correlated significantly with dental plaque scores and field of the study. Thus, OHL assessment is essential to understand a person’s OHL levels and can be considered a screening tool for early detection of poor oral hygiene.

scholarly journals The Role of Matrix Metalloproteinases in Periodontal Disease

2020 ◽  
Vol 17 (14) ◽  
pp. 4923 ◽  
Author(s):  
Vittorio Checchi ◽  
Tatjana Maravic ◽  
Pierantonio Bellini ◽  
Luigi Generali ◽  
Ugo Consolo ◽  
...  
Keyword(s):  
Matrix Metalloproteinases ◽  
Periodontal Disease ◽  
Anaerobic Bacteria ◽  
Therapeutic Strategies ◽  
Oral Diseases ◽  
Tissue Destruction ◽  
Proinflammatory Mediators ◽  
Disease Therapy ◽  
Important Pathway

This review provides a detailed description of matrix metalloproteinases (MMPs), focusing on those that are known to have critical roles in bone and periodontal disease. Periodontal disease is an inflammatory process initiated by anaerobic bacteria, which promote the host immune response in the form of a complex network of molecular pathways involving proinflammatory mediators such as cytokines, growth factors, and MMPs. MMPs are a family of 23 endopeptidases, collectively capable of degrading virtually all extracellular matrix (ECM) components. This study critically discusses the available research concerning the involvement of the MMPs in periodontal disease development and progression and presents possible therapeutic strategies. MMPs participate in morphogenesis, physiological tissue turnover, and pathological tissue destruction. Alterations in the regulation of MMP activity are implicated in the manifestation of oral diseases, and MMPs comprise the most important pathway in tissue destruction associated with periodontal disease. MMPs can be considered a risk factor for periodontal disease, and measurements of MMP levels may be useful markers for early detection of periodontitis and as a tool to assess prognostic follow-ups. Detection and inhibition of MMPs could, therefore, be useful in periodontal disease prevention or be an essential part of periodontal disease therapy, which, considering the huge incidence of the disease, may greatly improve oral health globally.

scholarly journals Antimicrobial and Substantivity Properties of Silver Nanoparticles against Oral Microbiomes Clinically Isolated from Young and Young-Adult Patients

2019 ◽  
Vol 2019 ◽  
pp. 1-14 ◽  
Author(s):  
León Francisco Espinosa-Cristóbal ◽  
Carolina Holguín-Meráz ◽  
Erasto Armando Zaragoza-Contreras ◽  
Rita Elizabeth Martínez-Martínez ◽  
Alejandro Donohue-Cornejo ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Young Adult ◽  
Dental Caries ◽  
Periodontal Disease ◽  
Dental Plaque ◽  
Bacterial Species ◽  
Inhibitory Effect ◽  
Oral Bacteria ◽  
Oral Microbiome ◽  
Oral Biofilms

The dental plaque is an oral microbiome hardly associated to be the etiological agent of dental caries and periodontal disease which are still considered serious health public problems. Silver nanoparticles (AgNPs) have demonstrated to have good antimicrobial properties affecting a wide variety of microorganisms, including oral bacteria; however, there is no scientific information that has evaluated the antimicrobial effect of AgNPs against clinical oral biofilms associated with dental caries and periodontal disease. The aim of this study was to determine the antimicrobial and substantivity effects of AgNPs in oral biofilms isolated clinically from patients with dental caries and periodontal disease. Sixty-seven young and young-adult subjects with dental caries and periodontal disease were clinically sampled through the collection of subgingival dental plaque. The inhibitory effect of AgNPs was performed with standard microbiological assays by triplicate using two sizes of particle. Polymerase chain reaction (PCR) assay was used to identify the presence of specific bacterial species. All AgNPs showed an inhibitory effect for all oral biofilms for any age and, generally, any gender (p>0.05); however, the effectiveness of the antimicrobial and substantivity effects was related to particle size, time, and gender (p<0.05). The identified microorganisms were S. mutans, S. sobrinus, S. sanguinis, S. gordonii, S. oralis, P. gingivalis, T. forsythia, and P. intermedia. The AgNPs could be considered as a potential antimicrobial agent for the control and prevention of dental caries and periodontal disease.

scholarly journals Caries and periodontal disease: Two diseases, one biofilm

2005 ◽  
Vol 26 (3) ◽  
pp. 110 ◽  
Author(s):  
Annetta K L Tsang ◽  
Saso Ivanovski ◽  
Philip S Bird
Keyword(s):  
Dental Caries ◽  
Periodontal Disease ◽  
Dental Plaque ◽  
Periodontal Diseases ◽  
Host Susceptibility ◽  
Alternative View ◽  
Oral Biofilm ◽  
Number Of Factors ◽  
Oral Ecology ◽  
Diverse Microbial Community

Dental plaque, a natural oral biofilm is involved in the aetiology of dental caries and periodontal disease. Despite decades of research, the microbiology, aetiology and pathogenesis of these diseases remain controversial. A number of factors interplay in these diseases, the indigenous microbes that inhabit the oral cavity, diet, host susceptibility and time. The ?Non-Specific Plaque Hypothesis? (NSPH) was proposed where the overall mass of plaque interacted with the host and caused disease. An alternative view was the ?Specific Plaque Hypothesis? (SPH) where, among the diverse microbial community, a limited subset of specific bacteria were associated with disease. In recent years, the ?Ecological Plaque Hypothesis? (EPH) has been proposed that it be recognised that the oral ecology as a whole contributes to the aetiology of dental caries and periodontal diseases, with shifts in the composition of microbial communities being of particular importance.

Psilocybin-assisted therapy for depression: How do we advance the field?

2019 ◽  
Vol 54 (3) ◽  
pp. 225-231 ◽  
Author(s):  
Sally E Meikle ◽  
Paul Liknaitzky ◽  
Susan L Rossell ◽  
Margaret Ross ◽  
Nigel Strauss ◽  
...  
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Potential Role ◽  
Treatment Options ◽  
Clinical Environment ◽  
Psychedelic Drugs ◽  
Key Issues ◽  
New Treatment ◽  
Potential Use

In the quest for new treatment options for depression, attention is being paid to the potential role of psychedelic drugs. Psilocybin is of particular interest given its mechanism of action, its benefits in early trials and its relatively low side effects burden. This viewpoint outlines a number of key issues that remain to be elucidated about its potential use in the clinical environment, including clarification of the profile of people most likely to benefit and those who might experience adverse effects, longer-term outcomes and the role of psychotherapeutic input alongside the drug itself. There are also opportunities to understand better, the neurobiology underpinning its effects.

scholarly journals Salivary Redox Biomarkers in the Course of Caries and Periodontal Disease

2020 ◽  
Vol 10 (18) ◽  
pp. 6240
Author(s):  
Anna Skutnik-Radziszewska ◽  
Anna Zalewska
Keyword(s):  
Oxidative Stress ◽  
Periodontal Disease ◽  
Dental Plaque ◽  
Pathological Process ◽  
Clinical Use ◽  
Biological Variability ◽  
Oral Diseases ◽  
Stress Markers ◽  
Inorganic Substances ◽  
The Relationship

Caries are a pathological process of extracorporeal nature, characterized by demineralization of inorganic substances as well as proteolysis triggered by acids produced by bacteria present in dental plaque, as a result of metabolism of sugars of both external and internal origin. Periodontal disease, on the other hand, is a multifactorial degenerative disease associated with inflammation, involving a group of tissues that surround the dental cervix and root of the tooth. It is believed that one of the mechanisms in the etiopathogenesis of caries and periodontitis are disorders of local and/or general oxidative stress (OS) parameters. Numerous clinical studies have confirmed the relationship between oxidative stress markers and oral diseases. In most analyzed studies, technical and biological variability was so high that none of the markers so far has proven suitable for routine clinical use. The aim of systematic reviews of the literature is to present the existing studies on OS parameters, mainly concerning the activity of antioxidant enzymes in saliva of patients with caries and periodontitis.

Oral health status in relation to nutritional status among kindergarten children aged (4-5) years old in Karbala city / Iraq

2019 ◽  
Vol 14 (1) ◽  
pp. 72
Author(s):  
Dr. Dhuha M. Hassan ◽  
Dr. Baydaa Hussien Hussien
Keyword(s):  
Dental Caries ◽  
Nutritional Status ◽  
Body Mass ◽  
Dental Plaque ◽  
Kindergarten Children ◽  
Plaque Index ◽  
Gingival Index ◽  
Oral Diseases ◽  
Significant Difference ◽  
The Mean

Back ground: Dental caries and periodontal disease were the most common andwidely spread diseases affecting children. The nutrition may be one of the factorsaffecting the severity of the oral diseases. The Aims of this study was theassessment of the following oral diseases (dental caries, gingivitis) in addition toassessment of oral hygiene among 4-5 years old children in Karbala city –Iraq.Furthermore, nutritional status was assessed in relation to oral diseases.Materials and methods: A sample of 658 children (350 males, 308 females) agedfour and five years old was selected randomly from the fourteenth kindergartensin Karbala city. Diagnosis and recording of dental caries was followed the criteriaof WHO 1987. Dental plaque was assessed using plaque index of Silness and Loe,1964. Gingival health condition was assessed using gingival index of Loe andSilness, 1963. The assessment of nutritional status was performed usinganthropometric measurement (height and weight) according to Body mass indexindicator with -2SD cutoff point.Results: Caries prevalence was found to be (83%) of the total sample the mean rankvalue of dmfs was higher among boys in comparison to girls with statistically nosignificant difference (P>0.05). The value of dmfs increased with age withstatistically highly significant difference (p<0.01).The mean rank values of dentalplaque and gingival indices for total boys were found to be higher than total girlswith statistically highly significant differences (P<0.01). Recording of this studydemonstrated that 100% of children had dental plaque and gingival inflammation.Positive highly significant correlations were recorded between dental caries withdental plaque and gingival indices. The prevalence of malnutrition described byBody mass index indicator was (3.2%). According to nutritional status indicatorBody mass index-for-age, it was found that the wasted children had higher valueof dmfs than well nourished children with statistically no significant differences(P>0.05). The plaque and gingival indices were higher among well nourishedchildren than among wasted children with statistically highly significantdifferences (P<0.01).The correlation coefficient between body mass index withdental caries, plaque index and gingival index were very weak and statistically notsignificant (p>0.05).Conclusions: High prevalence of dental caries and gingivitis was recorded indicatingthe need of public and preventive programs among kindergarten children.

A review on dental hygiene in children

2019 ◽  
Vol 7 (03) ◽  
Author(s):  
Ashwini Shitre
Keyword(s):  
Developing Countries ◽  
Early Childhood ◽  
Dental Caries ◽  
Early Childhood Caries ◽  
Dental Hygiene ◽  
Tooth Enamel ◽  
Oral Diseases ◽  
Effective Agent ◽  
Carious Teeth

Teeth are an integral part of the human body, not only for a contagious smile but also for chewing food well. Dental caries is one of the most common oral diseases in humans worldwide. However, dental caries, especially early childhood caries, is still a serious health problem in developing countries. An Ayurvedic remedy plays an effective agent in the treatment of carious teeth, owing to its ability to inhibit the growth and accumulation on the surface of the tooth. This would prevent the accumulation of acids on the surface of the tooth, and thus the further demineralization and the breakdown of the tooth enamel. In The present article we have tried to describe the role of Ayurveda in the management of dental hygiene.

scholarly journals Protein-Based Salivary Profiles as Novel Biomarkers for Oral Diseases

2018 ◽  
Vol 2018 ◽  
pp. 1-22 ◽  
Author(s):  
Alejandro I. Lorenzo-Pouso ◽  
Mario Pérez-Sayáns ◽  
Susana B. Bravo ◽  
Pía López-Jornet ◽  
María García-Vence ◽  
...  
Keyword(s):  
Dental Caries ◽  
Molecular Biology ◽  
Periodontal Disease ◽  
Global Burden ◽  
Oral Diseases ◽  
Biological Matrix ◽  
Severe Periodontal Disease ◽  
Novel Biomarkers ◽  
Proteins And Peptides ◽  
Untreated Dental Caries

The Global Burden of Oral Diseases affects 3.5 billion people worldwide, representing the number of people affected by the burden of untreated dental caries, severe periodontal disease, and edentulism. Thus, much more efforts in terms of diagnostics and treatments must be provided in the fight of these outcomes. In this sense, recently, the study of saliva as biological matrix has been identified as a new landmark initiative in the search of novel and useful biomarkers to prevent and diagnose these conditions. Specifically, saliva is a rich reservoir of different proteins and peptides and accessible due to recent advances in molecular biology and specially in targeted and unbiased proteomics technologies. Nonetheless, emerging barriers are an obstacle to the study of the salivary proteome in an effective way. This review aims at giving an overall perspective of salivary biomarkers identified in several oral diseases by means of molecular biology approaches.

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