scholarly journals The Development of Practice Recommendations for Drug-Disease Interactions by Literature Review and Expert Opinion

2020 ◽  
Vol 11 ◽  
Author(s):  
Justine M. Z. van Tongeren ◽  
S. Froukje Harkes-Idzinga ◽  
Heleen van der Sijs ◽  
Roya Atiqi ◽  
Bart J. F. van den Bemt ◽  
...  
2019 ◽  
Vol 34 (s1) ◽  
pp. s132-s132
Author(s):  
Rowena Christiansen

Introduction:Best practice first aid management of accidental hypothermia and cold injuries in the prehospital setting is relevant for disaster management in cold environments as well as for wilderness and expedition medicine, and space medicine. In the Australasian context, guidance is currently taken from the Australian Resuscitation Council (“ARC”) Guidelines dealing with these issues.Aim:To review and update the recommendations of the ARC Guideline 9.3.3 Hypothermia: First-Aid Management (February 2009) and ARC Guideline 9.3.6 Cold Injury (March 2000).Method: The review is being undertaken through a combination of a focused literature review and expert opinion. Through the author’s membership of the International Commission for Alpine Rescue (“ICAR”) Alpine Emergency Medicine Commission, two northern-hemisphere experts on hypothermia have reviewed the guidelines and provided commentary and recommendations.Results:Much of the literature around accidental hypothermia and cold injuries (including frostbite, frostnip, and chilblains), relies on expert opinion and case studies. There are relatively few randomized controlled trials, and these are often confined to the laboratory setting. As a result, there is a heavier reliance on expert opinion than in any other areas of medicine.Discussion:This presentation will summarize the current best practice recommendations for the first aid management of accidental hypothermia and cold injuries through combining the existing ARC Guidelines with key advances identified through the literature review, and the key management recommendations stemming from expert opinion. This will provide attendees with a cohesive set of clinical practice recommendations which can be used in the field.


Author(s):  
Anne Marie Dupuy ◽  
Anne Sophie Bargnoux ◽  
François Roubille ◽  
Jean Paul Cristol

AbstractOver the period from December 3rd, 2019 to March 13th, 2020, after the urgent field safety notice reported by Roche, we performed double determinations of all troponins from the same tube in parallel and in the same run. We used the same Elecsys troponin T hs reagent (ref 08469873190), first result was obtained with the current hs-cTnT application (18 min) and the second measurement was with the STAT application (9 min). On the 11,388 results in the range from 3 to 500 ng/L, we observed 4.18% discordant results (above 18.8% RCV). Overall, we observed an overestimation of the hs-cTnT STAT assay. The Elecsys Troponin T hs STAT assay demonstrated good analytical performances on Cobas e801 analyzer. However, its use according to the ESC recommendations for the 0 h/1 h algorithm should be carefully evaluated and requires further studies with serial cTn testing.


2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Alex A. Hesse ◽  
Rebecca A. Atadero ◽  
Mehmet E. Ozbek

A previous literature review indicated that there is little published experimental data that can be used to determine quantities such as bias, accuracy, reliability, and cost of common Nondestructive Evaluation (NDE) methods as far as their use on bridges is concerned. This study attempts to quantify these parameters for common bridge NDE methods through a four-round Delphi method survey with experts in the NDE bridge field. The survey results indicate that most commonly used bridge NDE methods tend to be underbiased and relatively reliable. Furthermore, the accuracy of commonly used bridge NDE methods tends to be relatively variable with the average test measuring a true response between 80% and 85% of the time. In general, it was shown by the participant responses that the more expensive the method was, the better the bias, accuracy, and reliability the method had, and vice versa. The information presented in this paper can serve as a starting point for characterizing different NDE methods for use in bridge management and inspection planning and identifies the type of information that is still needed. As such, this research has the potential to promote further research on this subject.


Author(s):  
. Perdiansyah ◽  
Asep Agus Handaka Suryana ◽  
Achmad Rizal ◽  
Atikah Nurhayati

Indonesia's fishing capture industry has very great potential in order to become the national economy's key driver. Change in population, pricing, technology, and productivity are the key indicators of trend. The objective of this study is to assess the evolution of Indonesian fisheries. This study was carried out at the Ministry of Maritime Affairs and Fisheries from August 2020 to July 2021. According to this study, 34 provinces in Indonesia were surveyed using a literature review method. Primary data in the form of expert opinion (expert judgment) consisting of 10 capable respondents. Secondary data was adopted from statistical data of the Ministry of Marine Affairs and Fisheries Center from 2005-2018. Data analysis was performed by using descriptive quantitative analysis techniques. The development of capture fisheries competitiveness in Indonesia has experienced fluctuating changes and tends to increase during 2006 to 2018.


2021 ◽  
Author(s):  
Manuela Di Fusco ◽  
Jay Lin ◽  
Shailja Vaghela ◽  
Melissa Lingohr-Smith ◽  
Jennifer L Nguyen ◽  
...  

AbstractIntroductionFrom July through October of 2021, several countries issued recommendations for increased COVID-19 vaccine protection for individuals with one or more immunocompromised (IC) conditions. It is critically important to understand the vaccine effectiveness (VE) of COVID-19 vaccines among IC populations as recommendations are updated over time in response to the evolving COVID-19 pandemic.Areas coveredA targeted literature review was conducted to identify real-world studies that assessed COVID-19 VE in IC populations between December 2020 and September 2021. A total of 10 studies from four countries were identified and summarized in this review.Expert opinion/commentaryVE of the widely available COVID-19 vaccines, including BNT162b2 (Pfizer/BioNTech), mRNA-1273 (Moderna), Ad26.COV2.S (Janssen), and ChAdOx1 nCoV-19 (Oxford/AstraZeneca), ranged from 64%-90% against SARS-CoV-2 infection, 73%-84% against symptomatic illness, 70%-100% against severe illness, and 63%-100% against COVID-19-related hospitalization among the fully vaccinated IC populations included in the studies. COVID-19 VE for most outcomes in the IC populations included in these studies was lower than in the general populations. These findings provide preliminary evidence that the IC population requires greater protective measures to prevent COVID-19 infection and associated illness, hence should be prioritized while implementing recommendations of additional COVID-19 vaccine doses.


2017 ◽  
Vol 298 ◽  
pp. 69-75
Author(s):  
Karolina Olszak-Häußler ◽  

Despite the fact that criminal profiling attracts massive media attention, our knowledge about the process of elaborating expert opinions containing criminal profiles is very limited. Based on the literature review, the author attempts to answer the questions: what is the objective of appointing an expert in the field of criminal profiling? and, which criteria should be applied to the evaluation of expert opinion?. Based on the content of the present article, it can be concluded that the current state of knowledge does not allow to determine unequivocally whether the profiler needs special knowledge, nor what should be the scope of such knowledge. Moreover, it cannot be clearly determined, whether the profile provides information of relevance to the resolution of the case. However, there is no doubt that wherever criminal profile takes the form of an expert opinion, it should be subject to very careful control, in accordance with the provisions of the Code of Criminal Procedure and doctrine recommendations regarding this matter.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Kamakshi Sharma ◽  
Mahima Jain ◽  
Sanjay Dhir

PurposeThis study explores the variables that drive the impact of artificial intelligence (AI) on the competitiveness of a tourism firm. The relationship between the variables is established using the modified total interpretive structural modelling (m-TISM) methodology. The factors are identified through literature review and expert opinion. This study investigates the hierarchical relationship between these variables.Design/methodology/approachThe modified total interpretive structural modelling (m-TISM) method is used to develop a hierarchical interrelationship among variables that display direct and indirect impact. The competitiveness of a tourism firm is measured by investigating the effect of variables on the firm's financial performance.FindingsThe study identifies ten key factors essential for analysing the impact of AI on a firm's competitiveness. The m-TISM methodology gave us the hierarchical relationship between the factors and their interpretation. A theoretical TISM model has been constructed based on the hierarchy and relationship of the elements. The elements that fall in Level V are “AI Skilled Workforce”, “Infrastructure” and “Policies and Regulations”. Level IV includes the elements “AI Readiness”, “AI-Enabled Technologies” and “Digital Platforms”. Elements that fall under Level III are “Productivity” and “AI Innovation”. Level II and Level I comprise “Tourist Satisfaction” and “Financial Performance”, respectively. The levels indicate the elements' hierarchical level, with Level I the highest and Level V the lowest.Research limitations/implicationsTourism and AI scholars can analyse the given variables by including the transitive links and incorporate new variables depending upon future research. The m-TISM model constructed from literature review and expert opinion can act as a theoretical base for future studies to be conducted by researchers.Practical implicationsManagement/Practitioners can focus on the available characteristics and capitalise on them while working on the factors lacking in their organisation to enhance their competitiveness. Entrepreneurs starting their own business can utilise the elements in understanding the ecosystem of strengthening a firm's competitiveness. They can work to improve on the aspects which are crucial and trigger the impact on competitiveness. The government and management can devise policies and strategies that encompass the essential factors that positively impact the competitiveness of the firms. The approach can then be looked at with a holistic approach to cater to the other related components of the tourism industry.Originality/valueThis study is the first of its kind to use the modified TISM methodology to understand the impact of AI on the competitiveness of tourism firms.


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