scholarly journals Three Selected Edible Crops of the Genus Momordica as Potential Sources of Phytochemicals: Biochemical, Nutritional, and Medicinal Values

2021 ◽  
Vol 12 ◽  
Author(s):  
Mashudu Muronga ◽  
Cristina Quispe ◽  
Phumudzo P. Tshikhudo ◽  
Titus A. M Msagati ◽  
Fhatuwani N. Mudau ◽  
...  

Momordica species (Family Cucurbitaceae) are cultivated throughout the world for their edible fruits, leaves, shoots and seeds. Among the species of the genus Momordica, there are three selected species that are used as vegetable, and for medicinal purposes, Momordica charantia L (Bitter melon), Momordica foetida Schumach (Bitter cucumber) and Momordica balsamina L (African pumpkin). The fruits and leaves of these Momordica species are rich in primary and secondary metabolites such as proteins, fibers, minerals (calcium, iron, magnesium, zinc), β-carotene, foliate, ascorbic acid, among others. The extracts from Momordica species are used for the treatment of a variety of diseases and ailments in traditional medicine. Momordica species extracts are reputed to possess anti-diabetic, anti-microbial, anthelmintic bioactivity, abortifacient, anti-bacterial, anti-viral, and play chemo-preventive functions. In this review we summarize the biochemical, nutritional, and medicinal values of three Momordica species (M. charantia, M. foetida and M. balsamina) as promising and innovative sources of natural bioactive compounds for future pharmaceutical usage.

2008 ◽  
Vol 3 (12) ◽  
pp. 1934578X0800301 ◽  
Author(s):  
Sônia S. Costa ◽  
Michelle F. Muzitano ◽  
Luiza M. M. Camargo ◽  
Marcela A. S. Coutinho

The Kalanchoe genus (syn. Bryophyllum), family Crassulaceae, comprises 125 species, most of them native to Madagascar. The great importance of several of these species for the traditional medicine in several regions of the World, esspecially India, Africa, China and Brazil, stimulated research programs into these plants from both a pharmacological and chemical point of view. The present review focuses on the main results obtained during the last decade on the secondary metabolites isolated from these species – endowed or not with a specific biological profile – with emphasis on flavonoids. The distribution of these molecules in the genus will be summarized and special attention will be given to K. brasiliensis and K. pinnata, two species well-known for healing inflammatory and infectious processes. Ornamental Kalanchoe species are also discussed as a potential source of bioactive compounds. This review covers the period 1970–2008.


2020 ◽  
Vol 15 (5) ◽  
pp. 1934578X2092712
Author(s):  
Tin Myo Thant ◽  
Nanik Siti Aminah ◽  
Alfinda Novi Kristanti ◽  
Rico Ramadhan ◽  
Hnin Thanda Aung ◽  
...  

The genus Micromelum belongs to the Rutaceae family. As its rich bioactive constituents its stems, flowers, leaves, and roots have been used in traditional medicine, for the treatment of various diseases from ancient time. Phytochemically, many bioactive compounds, including coumarins, polyoxygenated flavonoids, phenylpropanoic acid derivatives, quinolone alkaloids, and also carbazole alkaloids, have been reported as secondary metabolites of the Micromelum spp. including many new compounds. Therefore, Micromelum spp. are considered potential for drug leads. In this article, we present an overview of secondary metabolites isolated from genus Micromelum and their bioactivities that have been reported between 1982 and 2019.


2021 ◽  
Vol 181 (4) ◽  
pp. 37-43
Author(s):  
T. I. Fomina ◽  
T. A. Kukushkina

Background. Representatives of the genus Allium L. are valuable food and medicinal plants that have long been used for nutrition and human health. Modern research has proved their high biological activity. Earlier, we investigated the aboveground organs of a number of wild onion species in the consumer ripeness phase. Higher content of secondary metabolites has been observed in the hemiephemeroid species A. aflatunense B. Fedtsch., A. microdictyon Prokh., and A. rosenbachianum Regel. The aim of this work was to determine the content of bioactive compounds in the green biomass of Allium species during flowering.Materials and methods. We studied the freshly harvested raw materials – leaves and flower scapes. Dry matter content was measured by drying 1 g of raw material at 100–105°C to constant weight. The amounts of phenolic compounds, pectic substances, total sugars and carotenoids were assessed spectrophotometrically using the SF-56 (Russia) and SF Agilent 8453 (USA) instruments, and ascorbic acid was measured by the titrimetric method. The result was taken as an average of three measurements for each indicator calculated on absolute dry weight of raw material (except ascorbic acid).Results and conclusions. The green biomass of Allium species was found to contain 8,2–16,2% of dry matter; 4,5–12,0% of phenolics (catechins, flavonols and tannins); 6,9–32,4% of total sugars; 9,5–12,6% of pectic compounds (pectins and protopectins); 20,8–102,5 mg% of carotenoids, and 38,0–197,7 mg% of ascorbic acid (wet weight). A significant range of variation in the content of secondary metabolites was due to the species’ characteristics and weather conditions of the growing season. A. microdictyon had a higher content of dry matter, flavonols and tannins, whereas A. aflatunense and A. rosenbachianum were rich in ascorbic acid and sugars. The findings testify to the prospects of using Allium spp. as a source of bioactive compounds. 


2021 ◽  
Vol 21 (2) ◽  
Author(s):  
Chitra Kumari ◽  
Shyam Govind Singh

Spices are important for human being and have a long history of use in therapy throughout the world and still make an important role as traditional medicine. This review addresses the worldwide Mycoflora contamination which secretes secondary metabolites which known as mycotoxin. Mycoflora as major common contaminants of spices and that causes adverse effect on animal, crops and human that result in economic losses and illnesses. To prevent and screen for contamination and ensure safety and conformity to quality standard of spices and their products should be included in appropriate regulatory framework.


2021 ◽  
Author(s):  
Fadime Eryılmaz Pehlivan

Nature is full of poisons as well as life-saving entities. Extracts of natural products in medicinal plants have been used for thousands of years in traditional medicine throughout the World. Bitter melon (Momordica charantia) is a member of Cucurbitaceae family, widely distributed in tropical regions of the World, that has been used in folk medicine for the treatment of diabetes mellitus, and its fruit has been used as a vegetable for thousands of years. It contains phytochemicals, flavonoids, triterpenes, saponins, ascorbic acid, steroids, proteins, and polysaccharides. This plant is a traditional herbal medicine, possesses various biological, medicinal activities and pharmacological functions, namely antidiabetic, anthelmintic, contraceptive, antimalarial, laxative, antihyperglycemic, antimutagenic, antiulcer, antilipolytic, antifertility, hepatoprotective, anticancer, antibacterial, antiviral, antitumor, immunomodulation, antioxidant, antidiabetic, and anti-inflammatory activities of M. charantia have been reported. Its fruit has a special bitter taste, parts of M. charantia, such as fruits, vines, leaves and even roots have been used as folk medicine for the remedy of diseases like toothache, diarrhea, and diabetes. It is also used for the treatment of eczema, gout, jaundice, pneumonia, psoriasis, and rheumatism. These beneficial effects are attributed to the various bioactive components of M. charantia, which are important sources of phytoconstituents used to treat various diseases since ancient times. This chapter reviews various aspects of the results of investigations involving M. charantia in the recent years, providing a comprehensive overview of the phytochemical application of M. charantia to attract more attention to their biological activities for better utilization of M. charantia; focusing on the review of benefits that bitter melon offers in terms of its potential as a source of bioactive compounds and its role in the control of different diseases.


2020 ◽  
Vol 20 (1) ◽  
pp. 66-87 ◽  
Author(s):  
Mariangela Marrelli ◽  
Giancarlo Statti ◽  
Filomena Conforti

: Plants from the genus Hypericum, one genus of the Hypericaceae family, have attracted a lot of attention for their potential pharmaceutical applications. Most of the studies in the literature focus on H. perforatum L. (common St. John's wort), whose complex spectrum of bioactive compounds makes this species one of the top herbal remedies and supplements in the world. It is also important to compare the studies on other Hypericum species, both from the phytochemical and biological point of view. The aim of this review was to provide an update of most recent studies about biological investigations of plants belonging to Hypericum genus. The metabolic profiles of Hypericum spp. were also discussed in order to present a spectrum of secondary metabolites not previously identified in this genus.


2018 ◽  
Vol 17 (2) ◽  
Author(s):  
Trimanto Trimanto ◽  
Dini Dwiyanti ◽  
Serafinah Indriyani

Curcuma is a genus of family Zingiberaceae. Its rhizomes, as well as leaves, have long been used in the traditional medicine. This research aimed to examine the morphological and anatomical structure as well as the primary and secondary metabolites of Curcuma aeruginosa Roxb, Curcuma longa L, and Curcuma heyneana Valeton & Zijp. The Anatomical structure, histochemical test and secretory cell density were observed microscopically. The Histochemical test consisted of amilum, protein, lipid, tanin, alkaloid dan flavonoid tests. Observation of anatomical structures of the of rhizome showed that starch grains has a medium size and shape of starch was oval. Rhizomes of Curcuma longa and C. aeruginosa had a positive correlation for starch, protein, lipids, alkaloids, flavonoids and tannins. C. heyneana has the highest density value on protein while C. longa has the highest density value on lipids, alkaloids, flavonoids and tannins.


2021 ◽  
Vol 10 (2) ◽  
pp. 84-103
Author(s):  
Muhaimin Muhaimin ◽  
◽  
Muhammad Irhash Shalihin ◽  
Madyawati Latief ◽  
◽  
...  

Premna serratifolia known as bebuas has long been used by Malay comunity for both food and traditional medicine. The most notable advantage of this plant is to heal woman after childbirth and to raise the notion that contains anti-inflammatory bioactive compounds. In this study, the hexane extract of bebuas was only contained steroids. Meanwhile the ethanol extract contained various secondary metabolites such as phenolics, alkaloids, flavonoids, steroids and saponins. The ethanol extract was further separated since the targeted compound isolate was an alkaloid. The isolate obtained was a yellow crystal which transformed to yellow oil after being exposed to air. The anti-inflammatory evaluation of the compound gave a result with a strong activity with ED50 = 4.06 mg/KgBW. Characterization by UV-Vis and FT-IR showed that the isolate’s spectra pattern had similarities with bufotenine. It revealed that the isolate shared the same basic skeleton with the bufotenine, especially the indole skeleton. Furthermore, it also shared the same physical form with bufotenine. These evidences strengthened the assumption that the isolate was an indole alkaloid.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Rajani KS ◽  
Swasha Khandeparker Naik ◽  
Subhadarshini Satapathy ◽  
Sweta Mishra

The present study highlights preliminary phytochemical analysis of the leaf extract of Nyctanthes arbor-tristis. Plants produce a wide range of bioactive molecules which make them as a rich source of various types of medicines. Nyctanthes arbor-tristis is one of the well-known medicinal herbs of Indian origin belonging to family Oleaceae, commonly known as night Jasmine. The leaf extract is taken by percolation method. Various bioactive primary and secondary metabolites were tested using colour reactions with specific reagents. The study reveals that it contains some bioactive compounds which indicate that this plant might be used as anti-malarial, anti-viral and antidiabetic.


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