scholarly journals Electroencephalographic Parameters Differentiating Melancholic Depression, Non-melancholic Depression, and Healthy Controls. A Systematic Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Caroline Fussing Bruun ◽  
Caroline Juhl Arnbjerg ◽  
Lars Vedel Kessing
Keyword(s):  
Systematic Review ◽  
Event Related Potentials ◽  
Unipolar Depression ◽  
Control Group ◽  
Extensive Literature ◽  
Healthy Controls ◽  
Melancholic Depression ◽  
Related Potentials ◽  
The Individual ◽  
Almost All

Introduction: The objective of this systematic review was to investigate whether electroencephalographic parameters can serve as a tool to distinguish between melancholic depression, non-melancholic depression, and healthy controls in adults.Methods: A systematic review comprising an extensive literature search conducted in PubMed, Embase, Google Scholar, and PsycINFO in August 2020 with monthly updates until November 1st, 2020. In addition, we performed a citation search and scanned reference lists. Clinical trials that performed an EEG-based examination on an adult patient group diagnosed with melancholic unipolar depression and compared with a control group of non-melancholic unipolar depression and/or healthy controls were eligible. Risk of bias was assessed by the Strengthening of Reporting of Observational Studies in Epidemiology (STROBE) checklist.Results: A total of 24 studies, all case-control design, met the inclusion criteria and could be divided into three subgroups: Resting state studies (n = 5), sleep EEG studies (n = 10), and event-related potentials (ERP) studies (n = 9). Within each subgroup, studies were characterized by marked variability on almost all levels, preventing pooling of data, and many studies were subject to weighty methodological problems. However, the main part of the studies identified one or several EEG parameters that differentiated the groups.Conclusions: Multiple EEG modalities showed an ability to distinguish melancholic patients from non-melancholic patients and/or healthy controls. The considerable heterogeneity across studies and the frequent methodological difficulties at the individual study level were the main limitations to this work. Also, the underlying premise of shifting diagnostic paradigms may have resulted in an inhomogeneous patient population.Systematic Review Registration: Registered in the PROSPERO registry on August 8th, 2020, registration number CRD42020197472.

scholarly journals Decline in attentional inhibition among migraine patients: an event‐related potential study using the Stroop task

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Min Su ◽  
Rongfei Wang ◽  
Zhao Dong ◽  
Dengfa Zhao ◽  
Shengyuan Yu
Keyword(s):  
Stroop Task ◽  
Event Related Potentials ◽  
Brain Dysfunction ◽  
Event Related Potential ◽  
Control Group ◽  
Healthy Controls ◽  
Conflict Monitoring ◽  
Related Potentials ◽  
Migraine Group ◽  
Attentional Inhibition

Abstract Background As a disorder of brain dysfunction, migraine has been associated with cognitive decline. However, no consistent results with respect to the attention function in migraineurs have been found, and the relationship between attentional inhibition and migraine is also unclear. In this study, the attentional inhibition function was evaluated using event-related potentials (ERPs) while migraine patients and healthy controls were performing the color–word Stroop task. Methods In this study, 75 migraine patients and 41 age-, gender-, and education-matched healthy controls were enrolled. The Stroop task was performed, and both behavioral and ERP data were analyzed. Results As to the behavioral data, the migraine group had a longer reaction time compared to the control group, but no difference in Stroop effect was observed. With respect to ERP components, the amplitudes of both early and late medial frontal negativity (MFN) were decreased in the migraine group. Additionally, obvious differences in the early MFN and sustained potential (SP) amplitudes were found between patients with and without allodynia. Conclusions At the behavioral level, migraine patients exhibited decreased executive ability but no obvious decline in inhibition. By contrast, a decline in attentional inhibition during the migraine interictal phase was confirmed by the analysis of ERP components, mainly those associated with changes in the conflict-monitoring stage, independent of confounding factors such as age, education, medication and mood disorders. Migraine patients with allodynia exhibited some significant differences in early MFN and SP compared to those without, supporting the hypothesis that migraine chronification aggravates the decline in attentional inhibition.

Cognitive Processing in Headache Associated with Sexual Activity

Cephalalgia ◽  
2003 ◽  
Vol 23 (7) ◽  
pp. 545-551 ◽  
Author(s):  
A Frese ◽  
K Frese ◽  
EB Ringelstein ◽  
I-W Husstedt ◽  
S Evers
Keyword(s):  
Sexual Activity ◽  
Cognitive Processing ◽  
Event Related Potentials ◽  
Control Group ◽  
Specific Information ◽  
Healthy Controls ◽  
Related Potentials ◽  
Healthy Control ◽  
P3 Amplitude

Cognitive processing as measured by event-related potentials (ERP) in patients suffering from the explosive subtype of headache associated with sexual activity (HSA type 2) was investigated. Visual ERP were measured in 24 patients with HSA type 2 outside the headache period. The differences of the first and the second part of measurement were evaluated separately to determine the amount of cognitive habituation. Twenty-four sex- and age-matched healthy subjects and 24 patients with migraine without aura served as controls. A missing increase of P3 latency during the second part of the measurement was found in 79% of patients with HSA type 2 and in 75% with migraine, but only in 17% of the healthy controls ( P < 0.001). The P3 amplitude was increased during the second part in 71% of patients with HSA type 2 and in 79% with migraine, but only in 33% of the healthy controls ( P = 0.02). Mean P3 latency was decreased and mean P3 amplitude was increased during the second part of the measurement in HSA type 2 and in migraine but not in the healthy control group. Patients with HSA type 2 have a loss of cognitive habituation as measured by ERP. This specific information processing is very similar to that in migraine observed in previous studies.

scholarly journals Working memory content guides attention

2021 ◽  
Vol 15 ◽  
pp. 183449092110347
Author(s):  
Yu Luo ◽  
Jiarong Zhou ◽  
Wei Bao ◽  
Jing Qiu ◽  
Jingqing Nian ◽  
...  
Keyword(s):  
Working Memory ◽  
State Anxiety ◽  
Working Memory Capacity ◽  
Event Related Potentials ◽  
Control Group ◽  
Related Potentials ◽  
Memory Content ◽  
New Perspective ◽  
The Individual ◽  
And Control

Previous studies showed that working memory (WM) content can guide attention; however, whether working memory capacity (WMC) and state anxiety could affect this remains unclear. This study aimed to examine the effect of WMC and state anxiety on attention guided by WM content. Participants with high and low WMC were assigned to either a neutral or an anxiety condition. They were asked to perform a modified change detection task with irrelevant singletons while their event-related potentials were recorded. N2pc and Pd were observed in the low-WMC and anxiety group, and Pd was observed in both the high-WMC and anxiety and the high-WMC and control groups, whereas neither N2pc nor Pd was found in the low-WMC and control group. These findings suggest that attention is guided or suppressed by WM content, depending on the WMC and anxiety level of the individual. This study provides a new perspective on WM content-guided attention.

scholarly journals The Deficit of Multimodal Perception of Congruent and Non-Congruent Fearful Expressions in Patients with Schizophrenia: The ERP Study

2021 ◽  
Vol 11 (1) ◽  
pp. 96
Author(s):  
Galina V. Portnova ◽  
Aleksandra V. Maslennikova ◽  
Natalya V. Zakharova ◽  
Olga V. Martynova
Keyword(s):  
Event Related Potentials ◽  
Emotional Valence ◽  
Control Group ◽  
Healthy Controls ◽  
Specific Symptom ◽  
Flat Affect ◽  
Emotional Perception ◽  
Emotional Dysfunction ◽  
Related Potentials ◽  
Multimodal Perception

Emotional dysfunction, including flat affect and emotional perception deficits, is a specific symptom of schizophrenia disorder. We used a modified multimodal odd-ball paradigm with fearful facial expressions accompanied by congruent and non-congruent emotional vocalizations (sounds of women screaming and laughing) to investigate the impairment of emotional perception and reactions to other people’s emotions in schizophrenia. We compared subjective ratings of emotional state and event-related potentials (EPPs) in response to congruent and non-congruent stimuli in patients with schizophrenia and healthy controls. The results showed the altered multimodal perception of fearful stimuli in patients with schizophrenia. The amplitude of N50 was significantly higher for non-congruent stimuli than congruent ones in the control group and did not differ in patients. The P100 and N200 amplitudes were higher in response to non-congruent stimuli in patients than in controls, implying impaired sensory gating in schizophrenia. The observed decrease of P3a and P3b amplitudes in patients could be associated with less attention, less emotional arousal, or incorrect interpretation of emotional valence, as patients differed from healthy controls in the emotion scores of non-congruent stimuli. The difficulties in identifying the incoherence of facial and audial components of emotional expression could be significant in understanding the psychopathology of schizophrenia.

scholarly journals Blunted Reward Processing in Remitted Melancholic Depression

2016 ◽  
Vol 5 (1) ◽  
pp. 14-25 ◽  
Author(s):  
Anna Weinberg ◽  
Stewart A. Shankman
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Symptoms ◽  
Event Related Potentials ◽  
Reward Processing ◽  
Healthy Controls ◽  
Neural Responses ◽  
Melancholic Depression ◽  
Major Depressive ◽  
Related Potentials ◽  
Monetary Gain

Blunted reward response appears to be a trait-like marker of vulnerability for major depressive disorder (MDD). As such, it should be present in remitted individuals; however, depression is a heterogeneous syndrome. Reward-related impairments may be more pronounced in individuals with melancholic depression. The present study examined neural responses to rewards in remitted melancholic depression (rMD; n = 29), remitted nonmelancholic depression (rNMD; n = 56), and healthy controls (HC; n = 81). Event-related potentials to monetary gain and loss were recorded during a simple gambling paradigm. Relative to both the HC and the rNMD groups, who did not differ from one another, rMD was characterized by a blunted response to rewards. Moreover, the rMD and rNMD groups did not differ in course or severity of their past illnesses, or current depressive symptoms or functioning. Results suggest that blunted response to rewards may be a viable vulnerability marker for melancholic depression.

EEG Measurement of Emotion Processing in Children with Daytime Urinary Incontinence

2018 ◽  
Vol 46 (4) ◽  
pp. 336-341
Author(s):  
Justine Niemczyk ◽  
Monika Equit ◽  
Katja Rieck ◽  
Mathias Rubly ◽  
Catharina Wagner ◽  
...  
Keyword(s):  
Urinary Incontinence ◽  
Patient Group ◽  
Imaging Techniques ◽  
Emotion Processing ◽  
Event Related Potentials ◽  
Oddball Paradigm ◽  
Control Group ◽  
Central Processing ◽  
Daytime Urinary Incontinence ◽  
Related Potentials

Abstract. Objective: Daytime urinary incontinence (DUI) is common in childhood. The aim of the study was to neurophysiologically analyse the central emotion processing in children with DUI. Method: In 20 children with DUI (mean age 8.1 years, 55 % male) and 20 controls (mean age 9.1 years, 75 % male) visual event-related potentials (ERPs) were recorded after presenting emotionally valent (80 neutral, 40 positive, and 40 negative) pictures from the International Affective Picture System (IAPS) as an oddball-paradigm. All children received a full organic and psychiatric assessment. Results: Children with DUI did not differ significantly from controls regarding responses to emotional pictures in the frontal, central, and parietal regions and in the time intervals 250–450 ms, 450–650 ms, and 650–850 ms after stimulus onset. The patient group had more psychological symptoms and psychiatric comorbidities than the control group. Conclusions: EEG responses to emotional stimuli are not altered in children with DUI. Central emotion processing does not play a major role in DUI. Further research, including a larger sample size, a more homogeneous patient group (regarding subtype of DUI) or brain imaging techniques, could reveal more about the central processing in DUI.

Suicidal thoughts, behaviors, and event‐related potentials: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Austin J. Gallyer ◽  
Sean P. Dougherty ◽  
Kreshnik Burani ◽  
Brian J. Albanese ◽  
Thomas E. Joiner ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Event Related Potentials ◽  
Suicidal Thoughts ◽  
Related Potentials

Effects of cannabis use on event related potentials in subjects at ultra high risk for psychosis and healthy controls

2013 ◽  
Vol 88 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Mirjam J. van Tricht ◽  
Emma C. Harmsen ◽  
Johannes H.T.M. Koelman ◽  
Lo J. Bour ◽  
Thérèse A. van Amelsvoort ◽  
...  
Keyword(s):  
High Risk ◽  
Event Related Potentials ◽  
Cannabis Use ◽  
Healthy Controls ◽  
Ultra High Risk ◽  
Related Potentials

scholarly journals Monitoring Migraine Cycle Dynamics with an Easy-to-Use Electrophysiological Marker—A Pilot Study

Sensors ◽  
2018 ◽  
Vol 18 (11) ◽  
pp. 3918 ◽  
Author(s):  
Goded Shahaf ◽  
Pora Kuperman ◽  
Yuval Bloch ◽  
Shahak Yariv ◽  
Yelena Granovsky
Keyword(s):  
Pilot Study ◽  
Stress Level ◽  
Event Related Potentials ◽  
Healthy Controls ◽  
Preliminary Results ◽  
Auditory Oddball ◽  
Control Subjects ◽  
Related Potentials ◽  
Auditory Oddball Task ◽  
The Brain

Migraine attacks can cause significant discomfort and reduced functioning for days at a time, including the pre-ictal and post-ictal periods. During the inter-ictsal period, however, migraineurs seem to function normally. It is puzzling, therefore, that event-related potentials of migraine patients often differ in the asymptomatic and inter-ictal period. Part of the electrophysiological dynamics demonstrated in the migraine cycle are attention related. In this pilot study we evaluated an easy-to-use new marker, the Brain Engagement Index (BEI), for attention monitoring during the migraine cycle. We sampled 12 migraine patients for 20 days within one calendar month. Each session consisted of subjects’ reports of stress level and migraine-related symptoms, and a 5 min EEG recording, with a 2-electrode EEG device, during an auditory oddball task. The first minute of the EEG sample was analyzed. Repetitive samples were also obtained from 10 healthy controls. The brain engagement index increased significantly during the pre-ictal (p ≈ 0.001) and the ictal (p ≈ 0.020) periods compared with the inter-ictal period. No difference was observed between the pre-ictal and ictal periods. Control subjects demonstrated intermediate Brain Engagement Index values, that is, higher than inter-ictal, yet lower than pre-ictal. Our preliminary results demonstrate the potential advantage of the use of a simple EEG system for improved prediction of migraine attacks. Further study is required to evaluate the efficacy of the Brain Engagement Index in monitoring the migraine cycle and the possible effects of interventions.

Sign in / Sign up

Export Citation Format

Share Document