scholarly journals Predicting the Potential Applicability to Other Technical Fields Through the Linkage Between Backward and Forward Citations

2021 ◽  
Vol 6 ◽  
Author(s):  
Masayuki Hirose
Keyword(s):  
Early Stage ◽  
Japanese Patent ◽  
Patent Classification ◽  
Starting Point ◽  
The Us ◽  
Potential Applicability ◽  
The Subject ◽  
Research Questions ◽  
Patent Applications ◽  
Forward Citations

This article is a modest attempt to shed some light on the question of linkages between backward and forward citations in technical fields posed by Trajtenberg et al. (1997). They found interesting similarities and high correlations between equivalent measures looking forward and backward. They also implied the linkage between distant backward and distant forward citations. There are several questions to be posed in applying their insights to Japanese patent applications, however, due to the differences in the patent classification system and the subject of citation, i.e., citations by the applicant or examiner, between the US and Japan. In addition, and most importantly, the possibility that subsequent classifications may match, even if the first classification is different, is unavoidable with existing measurement methods of technical distance. In order to investigate these research questions, the author proposes a new measurement method for the technological proximity between examiner’s citations and their originating patents using IPC-based patent classifications. Using such a proposed method, the author created two hypotheses and tested them for about 14,000 examined patent applications filed in 2008 with the JPO. As a result of testing Hypothesis I, the author confirmed that Trajtenberg et al.’s insights can be applied to Japanese patent applications using citations by the examiners and IPC-based patent classifications. In other words, it was confirmed that patent applications citing backward citations categorized in a technical field distant from the invention are more likely to be cited by forward citations categorized in a technical field distant from the invention. As a result of the verification of Hypothesis Ⅱ, it was further confirmed in some technical fields that the backward citations categorized in a technical field distant from the invention are more likely to be in the same technical field as the forward citations categorized in a technical field distant from the invention. The author believes that these verified results indicate the possibilities of using backward citations as a starting point from which we can find patent applications for inventions at an early stage with potential applicability to other technical fields.

scholarly journals Feminist Scholarship and Its Relevance for Political Engagement: The Test Case of Abortion in the US

2011 ◽  
Vol 1 (1) ◽  
pp. 18-43
Author(s):  
Margaret D. Kamitsuka
Keyword(s):  
Identity Politics ◽  
Political Engagement ◽  
Religious Studies ◽  
Test Case ◽  
Theoretical Perspectives ◽  
Starting Point ◽  
The Us ◽  
The Subject ◽  
Ethical Thinking ◽  
Societal Dynamics

This essay explores how gender studies in academe, including in religious studies, might remain relevant to ongoing feminist political engagement. I explore some specific dynamics of this challenge, using as my test case the issue of abortion in the US. After discussing how three formative feminist principles (women’s experience as feminism’s starting point, the personal is political, and identity politics) have shaped approaches to the abortion issue for feminist scholars in religion, I argue that ongoing critique, new theoretical perspectives, and attentiveness to subaltern voices are necessary for these foundational feminist principles to keep pace with fast-changing and complex societal dynamics relevant to women’s struggles for reproductive health and justice. The essay concludes by proposing natality as a helpful concept for future feminist theological and ethical thinking on the subject.

Holism, Chinese Medicine and Systems Ideologies: Rewriting the Past to Imagine the Future

2018 ◽  
Author(s):  
Volker Scheid
Keyword(s):  
Eighteenth Century ◽  
Chinese Medicine ◽  
Medical Humanities ◽  
Science And Technology Studies ◽  
Human Beings ◽  
The Past ◽  
Starting Point ◽  
The Us ◽  
Shared Objective ◽  
Definition Of

This chapter explores the articulations that have emerged over the last half century between various types of holism, Chinese medicine and systems biology. Given the discipline’s historical attachments to a definition of ‘medicine’ that rather narrowly refers to biomedicine as developed in Europe and the US from the eighteenth century onwards, the medical humanities are not the most obvious starting point for such an inquiry. At the same time, they do offer one advantage over neighbouring disciplines like medical history, anthropology or science and technology studies for someone like myself, a clinician as well as a historian and anthropologist: their strong commitment to the objective of facilitating better medical practice. This promise furthermore links to the wider project of critique, which, in Max Horkheimer’s definition of the term, aims at change and emancipation in order ‘to liberate human beings from the circumstances that enslave them’. If we take the critical medical humanities as explicitly affirming this shared objective and responsibility, extending the discipline’s traditional gaze is not a burden but becomes, in fact, an obligation.

أسلوب التعليل القرآني وبعض آثاره التعليمية (The Principles of Qur’anic Argumentation and Its Educational Effects)

2017 ◽  
Vol 14 (1) ◽  
pp. 1-33
Author(s):  
رضوان جمال الأطرش ◽  
نجوى نايف شكوكاني
Keyword(s):  
Analytical Method ◽  
New Age ◽  
Traditional Education ◽  
Inductive Method ◽  
Education Effect ◽  
Starting Point ◽  
Innovative Thinking ◽  
The Subject ◽  
Practical Impact ◽  
Education Process

        الملخّص      هدف هذا البحث إبراز إمكانية التأثر العملي بأسلوب التعليل في القرآن الكريم، ومحاولة البحث في تطبيقاته في واقع العملية التعليمية من العالم والمتعلم، بحيث لم يقتصر على الدراسة اللغوية أو الأصولية النظرية؛ وخصوصاً بعد التعريف بهذا الأسلوب وأدواته وأهميته وبيان اللوازم الخاصة للعالم والمتعلم للتأثر به، وقد تم ذلك من خلال استخدام المنهج الاستقرائي بتتبع أعمال العلماء في ذلك وتم رصد أقوال المفسرين فيما يتعلق بالأساليب البيانية وآيات التعليل ووجوه الإعجاز القرآني، ومن ثم استُخدم المنهج التحليلي لإثبات ذلك الأثر وإثبات وجود إشارات وأدلة على مظاهر التأثر؛ واستنتاج حقيقة إمكانية استمرارية البحث في كل أدوات وآيات ومواضيع ذلك الأسلوب بنفس الطريقة التي تمّ طرحُها، مما يثري هذا المجال، ويفتح العقول ويدفعها للنظر والتدبر والبحث في آي القرآن، وفي كل المناحي، منطلقةً من فكر التجديد، والإفادة من مستجدات العصر وعلومه ضمن ضوابط العقيدة الغراء والشرع الحنيف. الكلمات المفتاحية: أسلوب التعليل، أدوات أسلوب التعليل، التدبر، التعليم التقليدي، أثر.  Abstract This study intends to highlight the possible practical impact of the principles of argumentation found in the Qur’an. The study attempts to apply the principles on the actual education process of the scholars and students without limiting it to linguistic studies or theoretical principles. This was done after introducing the principles of reasoning, its tools, its importance, and disclosing the special requirements for the scholars and students in order to be influenced by the latter principles.  The work used inductive method to track the works of the scholars on the subject and observe the opinions of the Qur’an-commentators in relation to principles of explanation, verses of argument, and aspects of Qur’anic Inimitability. Analytical method was used to establish the impacts of the Qur’anic arguments; to prove the presence of signs and evidences for the manifestation of the impacts; and to make the continuity of this research possible in all the tools, verses and topics related to the principles of Qur’anic argument. Among those things that enrich this work is that it opens the minds, and pushes it to ponder and study the verses of the Qur’an. For every direction it becomes the starting point for the innovative thinking, and benefit for the new age and its sciences while maintaining the harmony with the principles of creed and the true SharÊ‘ah. Keywords: Principles of Argumentation, Tools of Argumentation Principles, Thinking, Traditional Education, Effect.

THE TRUMP ADMINISTRATION’S APPROACH TO ENERGY SECURITY IN POLAND AND THE BALTIC STATES

2020 ◽  
Vol 18 (1/2020) ◽  
pp. 33-67
Author(s):  
Olga Stevanovic
Keyword(s):  
Energy Security ◽  
Research Question ◽  
Energy Resources ◽  
Baltic States ◽  
Realist Theory ◽  
Main Research ◽  
Security Challenges ◽  
The Us ◽  
The Subject ◽  
The Baltic

The subject of this paper encompasses US policy towards Poland and the Baltic States regarding energy security during Donald Trump’s presidency. It is discernible that vast domestic energy resources have created an opportunity for the US to project more power to these countries, and the surrounding region. We argue that Trump and his administration’s perceptions have served as an intervening variable in that opportunity assessment, in accordance with the neoclassical realist theory. The main research question addressed in this paper is whether US has used that opportunity to contribute to energy security in countries it has traditionally deemed as allies. Two aspects of US approach to energy security of the designated countries are taken into consideration: liquified natural gas exports and support for the Three Seas Initiative. The way Trump presented his policy and its results in his public statements has also been considered in this paper. The article will proceed as follows. The first subsection of the paper represents a summary of energy security challenges in Poland and the Baltic States. The second subsection is dedicated to the opportunity for the US to project energy power and to Trump’s perceptions relevant for the opportunity assessment. The third subsection deals with American LNG exports to these countries as a possible way for contributing to energy security in Poland and the Baltic States. The last part of the paper addresses the Three Seas Initiative and US approach to this platform.

Introduction

2017 ◽  
Author(s):  
Violeta Moreno-Lax
Keyword(s):  
Global Scale ◽  
Fundamental Rights ◽  
Eu Law ◽  
Migration Management ◽  
Charter Of Fundamental Rights ◽  
Scope Of Application ◽  
The Subject ◽  
Integrated Interpretation ◽  
Research Questions ◽  
Interpretation Model

This chapter presents the subject matter under scrutiny and provides a historical account of the development of extraterritorial strategies of migration management in Europe, coinciding with parallel changes in refugee movements and the composition of migratory flows on the global scale. The objective and research questions the study seeks to address are also introduced, together with a description of the methodology underpinning the research. In particular, the ‘cumulative standards’ or ‘integrated interpretation’ model employed to construe EU Charter of Fundamental Rights standards is canvassed. The concept of ‘jurisdiction’ and the alternative ‘Fransson paradigm’ applicable to interpret the scope of application of EU law is also briefly defined. The structure of the book is outlined at the end, providing an overview of the different chapters and their interrelation.

TTIP, CETA, and TiSA Behind Closed Doors

2017 ◽  
Author(s):  
Panagiotis Delimatsis
Keyword(s):  
European Union ◽  
Global Governance ◽  
Early Stage ◽  
European Parliament ◽  
Trade Negotiations ◽  
The European Union ◽  
The Us ◽  
The Eu

Secrecy and informality rather than transparency traditionally reign trade negotiations at the bilateral, regional, and multilateral levels. Yet, transparency ranks among the most basic desiderata in the grammar of global governance and has been regarded as positively related to legitimacy. In the EU’s case, transparent trade diplomacy is quintessential for constitutional—but also for broader political—reasons. First, even if trade matters fall within the EU’s exclusive competence, the EU executive is bound by the Treaty on the Functioning of the European Union (TFEU) to inform the European Parliament, the EU co-legislator, in regular intervals. Second, transparency at an early stage is important to address public reluctance, suspicion, or even opposition regarding a particular trade deal. This chapter chronicles the quest for and turning moments relating to transparency during the EU trade negotiations with Canada (CETA); the US (TTIP), and various WTO members on services (TiSA).

scholarly journals Toxicity Induced by Cytokines, Glucose, and Lipids Increase Apoptosis and Hamper Insulin Secretion in the 1.1E7 Beta Cell-Line

2021 ◽  
Vol 22 (5) ◽  
pp. 2559
Author(s):  
Antonia Diaz-Ganete ◽  
Aranzazu Quiroga-de-Castro ◽  
Rosa M. Mateos ◽  
Francisco Medina ◽  
Carmen Segundo ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Cell Line ◽  
High Glucose ◽  
Secretory Pathway ◽  
Early Stage ◽  
Hybrid Cell ◽  
Basic Research ◽  
Stress Markers ◽  
Beta Cell Line ◽  
Starting Point

Basic research on types 1 and 2 diabetes mellitus require early stage studies using beta cells or cell lines, ideally of human origin and with preserved insulin secretion in response to glucose. The 1.1E7 cells are a hybrid cell line resulting from the electrofusion of dispersed human islets and PANC-1 cells, capable of secreting insulin in response to glucose, but their survival and function under toxic conditions remains untested. This characterization is the purpose of the present study. We treated these cells with a cytokine mix, high glucose, palmitate, and the latter two combined. Under these conditions, we measured cell viability and apoptosis (MTT, Caspase Glo and TUNEL assays, as well as caspase-8 and -9 levels by Western blotting), endoplasmic reticulum stress markers (EIF2AK3, HSPA4, EIF2a, and HSPA5) by real-time PCR, and insulin secretion with a glucose challenge. All of these stimuli (i) induce apoptosis and ER stress markers expression, (ii) reduce mRNA amounts of 2–5 components of genes involved in the insulin secretory pathway, and (iii) abrogate the insulin release capability of 1.1E7 cells in response to glucose. The most pronounced effects were observed with cytokines and with palmitate and high glucose combined. This characterization may well serve as the starting point for those choosing this cell line for future basic research on certain aspects of diabetes.

The first century of English protestantism and the growth of national identity

1982 ◽  
Vol 18 ◽  
pp. 309-317 ◽  
Author(s):  
Anthony Fletcher
Keyword(s):  
National Identity ◽  
Early Modern Period ◽  
First Century ◽  
English Reformation ◽  
John Foxe ◽  
Religious Attitudes ◽  
The Bible ◽  
Starting Point ◽  
The Subject ◽  
Religious Zeal

Their sense of national identity is not something that men have been in the habit of directly recording. Its strength or weakness, in relation to commitment to international causes or to localist sentiment, can often only be inferred by examining political and religious attitudes and personal behaviour. So far as the early modern period is concerned, the subject is hazardous because groups and individuals must have varied enormously in the extent to which national identity meant something to them or influenced their lives. The temptation to generalise must be resisted. It is all too easy to suppose that national identity became well established in England in the Tudor century, when a national culture, based on widespread literacy among gentry, yeomen and townsmen, flowered as it had never done before, when the bible was first generally available in English, when John Foxe produced his celebrated Acts and Monuments, better known as the Book of Martyrs. Recent work reassessing the significance of Foxe’s account of the English reformation and other Elizabethan polemical writings provdes a convenient starting point for this brief investigation of some of the connections between religious zeal and national consciousness between 1558 and 1642.

A corpus-based investigation of techno-optimism and propositional certainty in the National Intelligence Council’s ‘Future Global Trends Reports’ (2010–2035)

2017 ◽  
Vol 12 (1) ◽  
pp. 39-57
Author(s):  
Jamie McKeown
Keyword(s):  
Global Trends ◽  
Future Role ◽  
Ideological Bias ◽  
The Past ◽  
The Us ◽  
The Future ◽  
The Subject ◽  
Global Peace ◽  
Discursive Representations

This article reports the findings from a study of discursive representations of the future role of technology in the work of the US National Intelligence Council (NIC). Specifically, it investigates the interplay of ‘techno-optimism’ (a form of ideological bias) and propositional certainty in the NIC’s ‘Future Global Trends Reports’. In doing so, it answers the following questions: To what extent was techno-optimism present in the discourse? What level of propositional certainty was expressed in the discourse? How did the discourse deal with the inherent uncertainty of the future? Overall, the discourse was pronouncedly techno-optimist in its stance towards the future role of technology: high-technological solutions were portrayed as solving a host of problems, despite the readily available presence of low-technology or no-technology solutions. In all, 75.1% of the representations were presented as future categorical certainties, meaning the future was predominantly presented as a known and closed inevitability. The discourse dealt with the inherent uncertainty of the subject matter, that is, the future, by projecting the past and present into the future. This was particularly the case in relation to the idea of technological military dominance as a guarantee of global peace, and the role of technology as an inevitable force free from societal censorship.

From Bench to Bedside: New Technologies for Cancer Diagnosis and Treatment

2008 ◽  
Vol 5 (2) ◽  
Author(s):  
Michal-Ruth Schweiger ◽  
Hans Lehrach
Keyword(s):  
Cancer Diagnosis ◽  
New Technologies ◽  
Early Stage ◽  
Predictive Biomarkers ◽  
Patient Treatment ◽  
Malignant Neoplasms ◽  
Advanced Stage ◽  
Common Cause ◽  
The Us ◽  
Risk Patients

According to the centre for disease control (CDC) malignant neoplasms are the second most common cause of death in the US in 2004 (1). One of the major problems is that most of the cancers are diagnosed in an advanced stage, which prohibits curative treatment. In order to circumvent these problems, we need to develop strategies that allow identification of risk patients and tumors at an early stage. In addition, it is necessary to identify prognostic and predictive biomarkers that guide patient treatment at different stages of the disease.

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