scholarly journals Predicting Parasite Dynamics in Mixed-Use Trans-Himalayan Pastures to Underpin Management of Cross-Transmission Between Livestock and Bharal

2021 ◽  
Vol 8 ◽  
Author(s):  
Munib Khanyari ◽  
Kulbhushansingh R. Suryawanshi ◽  
E. J. Milner-Gulland ◽  
Eleanor Dickinson ◽  
Abhirup Khara ◽  
...  
Keyword(s):  
Disease Transmission ◽  
North India ◽  
Health Issues ◽  
Transmission Potential ◽  
Infective Larvae ◽  
The North ◽  
Intestinal Nematode ◽  
Mixed Use ◽  
Parasite Infections ◽  
Cross Transmission

The complexities of multi-use landscapes require sophisticated approaches to addressing disease transmission risks. We explored gastro-intestinal nematode (GINs) infections in the North India Trans-Himalayas through a socio-ecological lens, integrating parasite transmission modelling with field surveys and local knowledge, and evaluated the likely effectiveness of potential interventions. Bharal (blue sheep; Pseudois nayaur), a native wild herbivore, and livestock share pasture year-round and livestock commonly show signs of GINs infection. While both wild and domestic ungulates had GINs infections, egg counts indicated significantly higher parasite burdens in bharal than livestock. However, due to higher livestock densities, they contributed more to the total count of eggs and infective larvae on pasture. Herders also reported health issues in their sheep and goats consistent with parasite infections. Model simulations suggested that pasture infectivity in this system is governed by historical pasture use and gradually accumulated larval development during the summer, with no distinct short-term flashpoints for transmission. The most effective intervention was consequently predicted to be early-season parasite suppression in livestock using temperature in spring as a cue. A 1-month pause in egg output from livestock could lead to a reduction in total annual availability of infective larvae on pasture of 76%, potentially benefitting the health of both livestock and bharal. Modelling suggested that climate change over the past 33 years has led to no overall change in GINs transmission potential, but an increase in the relative influence of temperature over precipitation in driving pasture infectivity. Our study provides a transferable multi-pronged approach to investigating disease transmission, in order to support herders' livelihoods and conserve wild ungulates.

scholarly journals Livestock movement informs the risk of disease spread in traditional production systems in East Africa

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Divine Ekwem ◽  
Thomas A. Morrison ◽  
Richard Reeve ◽  
Jessica Enright ◽  
Joram Buza ◽  
...  
Keyword(s):  
Disease Transmission ◽  
Production Systems ◽  
Control Strategies ◽  
Herd Size ◽  
Transmission Risk ◽  
Disease Spread ◽  
Transmission Potential ◽  
Spatial And Temporal Scales ◽  
Transmission Distance ◽  
Risk Of Disease

AbstractIn Africa, livestock are important to local and national economies, but their productivity is constrained by infectious diseases. Comprehensive information on livestock movements and contacts is required to devise appropriate disease control strategies; yet, understanding contact risk in systems where herds mix extensively, and where different pathogens can be transmitted at different spatial and temporal scales, remains a major challenge. We deployed Global Positioning System collars on cattle in 52 herds in a traditional agropastoral system in western Serengeti, Tanzania, to understand fine-scale movements and between-herd contacts, and to identify locations of greatest interaction between herds. We examined contact across spatiotemporal scales relevant to different disease transmission scenarios. Daily cattle movements increased with herd size and rainfall. Generally, contact between herds was greatest away from households, during periods with low rainfall and in locations close to dipping points. We demonstrate how movements and contacts affect the risk of disease spread. For example, transmission risk is relatively sensitive to the survival time of different pathogens in the environment, and less sensitive to transmission distance, at least over the range of the spatiotemporal definitions of contacts that we explored. We identify times and locations of greatest disease transmission potential and that could be targeted through tailored control strategies.

scholarly journals The effects of non-pharmaceutical interventions on SARS-CoV-2 transmission in different socioeconomic populations in Kuwait: a modeling study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fatima Khadadah ◽  
Abdullah A. Al-Shammari ◽  
Ahmad Alhashemi ◽  
Dari Alhuwail ◽  
Bader Al-Saif ◽  
...  
Keyword(s):  
Disease Transmission ◽  
Reproduction Number ◽  
Transmission Model ◽  
Socioeconomic Groups ◽  
Before And After ◽  
Cross Transmission ◽  
Community Transmission ◽  
The Impact ◽  
Pharmaceutical Interventions ◽  
The Basic Reproduction Number

Abstract Background Aggressive non-pharmaceutical interventions (NPIs) may reduce transmission of SARS-CoV-2. The extent to which these interventions are successful in stopping the spread have not been characterized in countries with distinct socioeconomic groups. We compared the effects of a partial lockdown on disease transmission among Kuwaitis (P1) and non-Kuwaitis (P2) living in Kuwait. Methods We fit a modified metapopulation SEIR transmission model to reported cases stratified by two groups to estimate the impact of a partial lockdown on the effective reproduction number ($$ {\mathcal{R}}_e $$ R e ). We estimated the basic reproduction number ($$ {\mathcal{R}}_0 $$ R 0 ) for the transmission in each group and simulated the potential trajectories of an outbreak from the first recorded case of community transmission until 12 days after the partial lockdown. We estimated $$ {\mathcal{R}}_e $$ R e values of both groups before and after the partial curfew, simulated the effect of these values on the epidemic curves and explored a range of cross-transmission scenarios. Results We estimate $$ {\mathcal{R}}_e $$ R e at 1·08 (95% CI: 1·00–1·26) for P1 and 2·36 (2·03–2·71) for P2. On March 22nd, $$ {\mathcal{R}}_e $$ R e for P1 and P2 are estimated at 1·19 (1·04–1·34) and 1·75 (1·26–2·11) respectively. After the partial curfew had taken effect, $$ {\mathcal{R}}_e $$ R e for P1 dropped modestly to 1·05 (0·82–1·26) but almost doubled for P2 to 2·89 (2·30–3·70). Our simulated epidemic trajectories show that the partial curfew measure greatly reduced and delayed the height of the peak in P1, yet significantly elevated and hastened the peak in P2. Modest cross-transmission between P1 and P2 greatly elevated the height of the peak in P1 and brought it forward in time closer to the peak of P2. Conclusion Our results indicate and quantify how the same lockdown intervention can accentuate disease transmission in some subpopulations while potentially controlling it in others. Any such control may further become compromised in the presence of cross-transmission between subpopulations. Future interventions and policies need to be sensitive to socioeconomic and health disparities.

Literary Conduits for ‘Consent’

2016 ◽  
Vol 19 (2) ◽  
pp. 322-350 ◽  
Author(s):  
Pankaj Kumar Jha
Keyword(s):  
Sixteenth Century ◽  
Fifteenth Century ◽  
North India ◽  
Indian Society ◽  
Historical Process ◽  
The North ◽  
Literary Cultures

The making of the imperial subjects is as much a matter of historical process as the emergence of the empire. In the case of the Mughal state, this process started much before its actual establishment in the sixteenth century. The fifteenth century in North India was a period of unusual cultural ferment. The emergence of the Mughal imperial formation in the next century was intimately related to the fast congealing tendency of the north Indian society towards greater disciplining of itself. This tendency is evident in the multilingual literary cultures and diverse knowledge formations of the long fifteenth century.

Hangings attended by ambulance clinicians in the North East of England

2021 ◽  
Vol 6 (3) ◽  
pp. 49-57
Author(s):  
Gary Shaw ◽  
Lee Thompson ◽  
Graham McClelland
Keyword(s):  
Mental Health ◽  
Cardiac Arrest ◽  
Suicide Attempts ◽  
Service Evaluation ◽  
Health Issues ◽  
Hospital Data ◽  
North East ◽  
The North ◽  
Acute Hospitals ◽  
Future Work

Introduction: Suicide rates have risen in England over the last decade and hanging, a highly lethal method of suicide, has been the most common method. Previous work in this area identified a lack of literature discussing emergency medical services (EMS) attendance at hangings. This article aims to describe hangings attended by EMS in the North East of England in order to inform future work in this area.Methods: A retrospective service evaluation was conducted using existing data from a comprehensive pre-hospital trauma audit database to describe patients with hanging documented in their records who were attended by ambulance clinicians between 1 December 2018 and 31 November 2020.Results: Hanging was recorded in 604 incidents. Most cases (n = 579/604) involved adults (aged 18 years or older) with a median age of 35 years (IQR 27‐45 years), who were male (n = 410/579, 71%). Just over half (n = 341/579, 59%) of adult hangings resulted in cardiac arrest and of these, 10% (n = 33/341) were resuscitated and survived to hospital admission. Threatened and non-fatal hangings appear to have increased dramatically in the latter half of 2020. Previous suicide attempts and mental health issues were frequently reported across this population.Conclusion: Hangings are a method of suicide which frequently result in a cardiac arrest. In the North East of England the ambulance service attends approximately one hanging per day and one fatal hanging every two days. When fatal hangings were resuscitated, pre-hospital outcomes were similar to other causes of cardiac arrest, highlighting that despite the traumatic nature of these cases resuscitation is not futile. In order to better understand this patient group and improve care, pre-hospital data need to be linked to data from other services such as mental health services and acute hospitals.

Reformism and Orthodox Practice in Early Nineteenth-Century Muslim North India: Sayyid Ahmed Shaheed Reconsidered

2011 ◽  
Vol 21 (2) ◽  
pp. 177-198
Author(s):  
SANA HAROON
Keyword(s):  
Nineteenth Century ◽  
North India ◽  
Ordinary People ◽  
Early Nineteenth Century ◽  
The North ◽  
The Creation

AbstractThis paper is a reconsideration of the career of the north-Indian Sayyid Ahmed Shaheed (1786–1831). I argue that Sayyid Ahmed used a Sufi devotional premise to understand and explain principles of orthodoxy. He also applied a concept of innate spiritual knowledge to reformed practice, suggesting that ordinary people, without scholarly training, could determine and apply the principles of orthodox practice of Islam for themselves and for others. His movement modified traditional seminary-centred teaching and leadership through the creation of a popular and easily transferrable system of practice rooted in the community and imprinted with the obligation to spread reformist teachings.

scholarly journals Livestock Movement Informs the Risk of Disease Spread in Traditional Production Systems in East Africa

2021 ◽  
Author(s):  
Divine Ekwem ◽  
Thomas A. Morrison ◽  
Richard Reeve ◽  
Jessica Enright ◽  
Joram Buza ◽  
...  
Keyword(s):  
Disease Transmission ◽  
Production Systems ◽  
Control Strategies ◽  
Herd Size ◽  
Disease Spread ◽  
Transmission Potential ◽  
Spatial And Temporal Scales ◽  
Transmission Distance ◽  
Cattle Movements ◽  
Risk Of Disease

Abstract In Africa, livestock are important to local and national economies, but their productivity is constrained by infectious diseases. Comprehensive information on livestock movements and contacts is required to devise appropriate disease control strategies; yet, understanding contact risk in systems where herds mix extensively, and where different pathogens can be transmitted at different spatial and temporal scales, remains a major challenge. We deployed Global Positioning System collars on cattle in 52 herds in a traditional agropastoral system in western Serengeti, Tanzania, to understand fine-scale movements and between-herd contacts, and to identify locations of greatest interaction between herds. We examined contact across spatiotemporal scales relevant to different disease transmission scenarios. Daily cattle movements increased with herd size and rainfall. Generally, contact was greatest away from households, during periods with low rainfall and in locations close to dipping points. We demonstrate how movements and contacts affect the risk of disease spread. For example, contact rate was relatively sensitive to the survival time of different pathogens in the environment, and less sensitive to transmission distance, at least over the range of values that we explored. We identify times and locations of greatest disease transmission potential and that could be targeted through tailored control strategies.

Abstract 16327: Clinical Profiles, Care Patterns, Outcomes and Sex Differences of Patients With STEMI in India: Insights From the North Indian ST-segment Elevation Myocardial Infarction (NORIN STEMI) Registry

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Arman Qamar ◽  
Sameer Arora ◽  
Puneet Gupta ◽  
Michael Hendrickson ◽  
Muthiah Vaduganathan ◽  
...  
Keyword(s):  
Sex Differences ◽  
Reperfusion Therapy ◽  
North India ◽  
Femoral Access ◽  
St Segment Elevation ◽  
The North ◽  
Lv Dysfunction ◽  
St Segment ◽  
Care Patterns ◽  
Almost All

Background: Although major strides have been made in the care of patients (pts) with STEMI in high-income countries, little is known about the characteristics, practice patterns, outcomes & sex differences of pts with STEMI in India. Methods: The NORIN STEMI registry is an ongoing investigator-initiated prospective cohort study of pts presenting with STEMI at tertiary medical centers in North India. This registry started enrolling pts in January 2019. Results: Of 3,635 participants enrolled to date, 16% were women & the median age was 55 (IQR 45-62) years with 33% aged <50 years. Prior to STEMI, 63% were smokers, 29% had hypertension, 24% diabetes, & 54% were obese or overweight (Figure). Overall, 11% were previously treated with aspirin or statins. Only 2% of these patients had health insurance, & 65% had lower socioeconomic status. Most (93%) initially presented to a non-PCI capable facility. Almost all received aspirin, statin, P2Y12i & heparin on presentation; 66% were treated with PCI (98% femoral access), 15% fibrinolysis alone, 3% both fibrinolysis & PCI, &21% were medically managed; symptom onset to balloon time was 2.9 (0.6-9) days. LVEF was <40% in 46% & mechanical complications occurred in 1.3% (n=35 VSD, n=12 severe MR). 30-day mortality was 9%. Women were less likely to receive PCI (58% vs 67%) & had a 2-fold higher mortality vs men (OR adj 2.1; 1.6-3.0; Figure). Conclusion: In this contemporary registry of pts with STEMI in North India, over a third were younger than 50 years & tobacco smoking was a dominant risk factor. There were significant delays in timely reperfusion therapy with resultant severe LV dysfunction present in over half & high mortality particularly in women. It is critical to identify barriers, increase awareness, and develop strategies to improve STEMI care in India.

scholarly journals Sex and relationships education for LGBT+ young people: Lessons from UK youth work

Sexualities ◽  
2020 ◽  
Vol 23 (7) ◽  
pp. 1155-1178 ◽  
Author(s):  
Eleanor Formby ◽  
Catherine Donovan
Keyword(s):  
Young People ◽  
Intimate Relationships ◽  
Third Sector ◽  
Original Research ◽  
Youth Work ◽  
Health Issues ◽  
North East ◽  
The North ◽  
School Based ◽  
Research Findings

Lesbian, gay, bisexual and trans (LGBT) inclusive sex and relationships education (SRE) is of growing interest. However, there is a lack of clarity about what LGBT inclusive SRE should/does look like in practice. This article addresses that uncertainty by examining original research findings on innovative youth work based SRE provided within an arts-based project run by a third sector organisation in the North East of England. The research is set within the context of three broad rationales for LGBT inclusive SRE: to support the mental health of LGBT+ young people; to tackle sexual health issues, and to address concerns about sexual encounters and intimate relationships. The article sets out research findings within four main themes concerning: young people’s experiences of formal SRE; young people’s attempts to acquire SRE informally; young people’s experiences of youth work based SRE; practitioners’ experiences of delivering youth work based SRE. It then draws on this data to make the case for dedicated youth work for LGBT+ young people, outlining its potential alongside school-based SRE.

scholarly journals Response to Wolf et al.: Furthering Debate over the Suitability of Trap-Neuter-Return for Stray Cat Management

Animals ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 362 ◽  
Author(s):  
Michael C. Calver ◽  
Heather M. Crawford ◽  
Patricia A. Fleming
Keyword(s):  
Public Health ◽  
Local Government ◽  
Data Collection ◽  
Empirical Data ◽  
Disease Transmission ◽  
Experimental Approach ◽  
Health Issues ◽  
Stray Cats ◽  
Stray Cat ◽  
Poor Welfare

To continue dialogue over proposed Australian trials of Trap-Neuter-Return (TNR), we applied a framework requiring identification of areas of agreement, areas of disagreement, and identification of empirical data collection required to resolve disagreements. There is agreement that Australia has a problem with stray cats, causing problems of impacts on wildlife, nuisance, disease transmission (including public health issues and exchange of diseases between stray cat and pet cat populations), poor welfare outcomes for stray cats, and an emotional burden on staff euthanising healthy stray cats. There is disagreement on whether (i) current measures are failing, leading to unacceptably high euthanasia levels, (ii) some contributors to the debate misunderstand TNR, (iii) TNR trials will reduce urban cat populations and associated problems, (iv) TNR is an ethical solution to cat overpopulation, and (v) some contributors to the debate promulgated misinformation. Although not everyone agrees that TNR trials should proceed, as a hypothetical exploration, we propose an experimental approach explicitly comparing TNR to alternatives. Trials could only be considered if other detailed and well-funded attempts at stray cat control focusing across an entire Local Government Area (LGA) prove ineffective.

scholarly journals Association of the pre-monsoon thermal field over north India and the western Tibetan Plateau with summer monsoon rainfall over India

2015 ◽  
Vol 33 (8) ◽  
pp. 1051-1058 ◽  
Author(s):  
S. D. Bansod ◽  
S. Fadnavis ◽  
S. P. Ghanekar
Keyword(s):  
Tibetan Plateau ◽  
Summer Monsoon ◽  
Asian Summer Monsoon ◽  
Summer Monsoon Rainfall ◽  
North India ◽  
Monsoon Region ◽  
The North ◽  
Western Tibetan Plateau ◽  
Asian Summer ◽  
Summer Monsoon Region

Abstract. In this paper, interannual variability of tropospheric air temperatures over the Asian summer monsoon region during the pre-monsoon months is examined in relation to Indian summer monsoon rainfall (ISMR; June to September total rainfall). For this purpose, monthly grid-point temperatures in the entire troposphere over the Asian summer monsoon region and ISMR data for the period 1949–2012 have been used. Spatial correlation patterns are investigated between the temperature field in the lower tropospheric levels during May over the Asian summer monsoon region and ISMR. The results indicate a strong and significant northwest–southeast dipole structure in the spatial correlations over the Indian region, with highly significant positive (negative) correlations over the regions of north India and the western Tibetan Plateau region – region R1 (north Bay of Bengal: region R2). The observed dipole is seen significantly up to a level of 850 hPa and eventually disappears at 700 hPa. Thermal indices evaluated at 850 hPa level, based on average air temperatures over the north India and western Tibetan Plateau region (TI1) and the north Bay of Bengal region (TI2) during May, show a strong, significant relationship with the ISMR. The results are found to be consistent and robust, especially in the case of TI1 during the period of analysis. A physical mechanism for the relationship between these indices and ISMR is proposed. Finally the composite annual cycle of tropospheric air temperature over R1 during flood/drought years of ISMR is examined. The study brings out the importance of the TI1 in the prediction of flood/drought conditions over the Indian subcontinent.

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