scholarly journals Numerical Analysis-Based Blast Resistance Performance Assessment of Cable-Stayed Bridge Components Subjected to Blast Loads

2020 ◽  
Vol 10 (23) ◽  
pp. 8511
Author(s):  
Jungwhee Lee ◽  
Keunki Choi ◽  
Chulhun Chung
Keyword(s):  
Numerical Analysis ◽  
Blast Resistance ◽  
Assessment Process ◽  
Public Nature ◽  
Bridge Structures ◽  
Set Up ◽  
Existing Bridges ◽  
Resistance Performance ◽  
Selection Of ◽  
Cable Stayed Bridges

Cable-stayed bridges are infrastructure facilities of a highly public nature; therefore, it is essential to ensure operational safety and prompt response in the event of a collapse or damage, which are caused by natural and social disasters. Among social disasters, blast accidents can occur in cable-stayed bridges as a result of explosions produced by vehicle collisions or terrorist attacks; this can lead to the degradation in their structural performances and subsequent collapse. In this research, a procedure to assess structural blast-resistance performance is suggested based on a numerical analysis approach, and the feasibility of the procedure is demonstrated by performing an example assessment. The suggested procedure includes (1) selection of major structural components that severely affect the global structural behavior, (2) set-up blast hazard scenarios consisting of various blast levels and locations, and (3) assessment of the components using numerical blast simulation. By performing an example assessment, the critical blast level for each component could be determined and the blast location that affects the considering components the most severely could be found as well. The scenario-based assessment process employed in this study is expected to facilitate the evaluation of bridge structures under blasts in both existing bridges and future designs.

scholarly journals Numerical Simulation on Dynamic Behavior of Slab–Column Connections Subjected to Blast Loads

2021 ◽  
Vol 11 (16) ◽  
pp. 7573
Author(s):  
Kwang Mo Lim ◽  
Taek Hee Han ◽  
Joo Ha Lee
Keyword(s):  
Numerical Analysis ◽  
Blast Resistance ◽  
Mesh Size ◽  
Material Model ◽  
Simulation Method ◽  
Blast Load ◽  
Blast Loads ◽  
Element Analysis ◽  
Model And Simulation ◽  
Resistance Performance

Although many studies on the blast-resistant performance of structures have focused mainly on single members such as beams and columns, there is little research on the behavior of joints that are subjected to blast loads. In this study, the structural behavior of a slab–column connection subjected to blast load was investigated using a numerical analysis method. LS-DYNA was used as a finite element analysis program, and in order to improve the accuracy of numerical analysis, mesh size, material model, and simulation method of blast load were determined through preliminary analysis. The effect of different restraints of the joints, depending on the position of the columns in the slab, on the blast resistance performance was investigated. As a result, the highly confined slab-interior column connection showed better behavior than other edge and corner columns. The drop panel installed between the lower column and the slab was effective in improving the blast-resistance performance of the slab–column connection. For a more accurate evaluation of blast resistance performance, it was suggested that various evaluation factors such as ductility ratio, reinforcing stress, and concrete fracture area can be considered along with the support rotation, which is an important evaluation factor suggested by many standards.

Platelet Anti-Aggregating Activity and Tolerance of Clopidogrel in Atherosclerotic Patients

1996 ◽  
Vol 76 (06) ◽  
pp. 0939-0943 ◽  
Author(s):  
B Boneu ◽  
G Destelle ◽  
Keyword(s):  
Platelet Aggregation ◽  
Large Scale ◽  
Bleeding Time ◽  
Antithrombotic Activity ◽  
Ambulatory Patients ◽  
Patients At Risk ◽  
Set Up ◽  
Ischemic Events ◽  
Large Scale Clinical Trial ◽  
Selection Of

SummaryThe anti-aggregating activity of five rising doses of clopidogrel has been compared to that of ticlopidine in atherosclerotic patients. The aim of this study was to determine the dose of clopidogrel which should be tested in a large scale clinical trial of secondary prevention of ischemic events in patients suffering from vascular manifestations of atherosclerosis [CAPRIE (Clopidogrel vs Aspirin in Patients at Risk of Ischemic Events) trial]. A multicenter study involving 9 haematological laboratories and 29 clinical centers was set up. One hundred and fifty ambulatory patients were randomized into one of the seven following groups: clopidogrel at doses of 10, 25, 50,75 or 100 mg OD, ticlopidine 250 mg BID or placebo. ADP and collagen-induced platelet aggregation tests were performed before starting treatment and after 7 and 28 days. Bleeding time was performed on days 0 and 28. Patients were seen on days 0, 7 and 28 to check the clinical and biological tolerability of the treatment. Clopidogrel exerted a dose-related inhibition of ADP-induced platelet aggregation and bleeding time prolongation. In the presence of ADP (5 \lM) this inhibition ranged between 29% and 44% in comparison to pretreatment values. The bleeding times were prolonged by 1.5 to 1.7 times. These effects were non significantly different from those produced by ticlopidine. The clinical tolerability was good or fair in 97.5% of the patients. No haematological adverse events were recorded. These results allowed the selection of 75 mg once a day to evaluate and compare the antithrombotic activity of clopidogrel to that of aspirin in the CAPRIE trial.

Selection of Airfoils for Vertical Axis Wind Turbines for Low Speed, Low Altitude Regions of Central India

2017 ◽  
Vol 7 (11) ◽  
pp. 113
Author(s):  
Abhineet Singh ◽  
Sonali Mitra ◽  
S.V.H. Nagendra ◽  
Pragyan Jain
Keyword(s):  
Numerical Analysis ◽  
Central India ◽  
Vertical Axis ◽  
College Campus ◽  
Low Speed ◽  
Vertical Axis Wind Turbines ◽  
Low Altitude ◽  
Naca 0015 ◽  
Naca 0012 ◽  
Selection Of

The present paper deals with the selection of airfoil profile for VAWTs which is to be installed in the college campus, located in Central India region. Both experimental and numerical analysis he been carried out for the three selected airfoils, NACA 0012, NACA 0015 & S2027. The results show a good correlation with the existing literature. Airfoil profile S2027 has been chosen which best suits our condition. 

STUDY OF INACCURACY IN THE OPERATION OF THE MAIN CONTROLLER OF STB MACHINE

2019 ◽  
Keyword(s):  
Normal Distribution ◽  
Stable Process ◽  
Random Errors ◽  
Actual Length ◽  
Experimental Data Processing ◽  
Set Up ◽  
Main Regulator ◽  
Transmission Gear ◽  
Selection Of

At production of fabrics, including fabrics for agricultural purpose, an important role is played by the cor-rect adjustment of operation of machine main regulator. The quality of setup of machine main controller is determined by the proper selection of rotation angle of warp beam weaving per one filling thread. In the pro-cess of using the regulator as a result of mistakes in adjustment, wear of transmission gear and backlashes in connections of details there are random changes in threads length. The purpose of the article is the research of property of random errors of basis giving by STB machine regulator. Mistakes can be both negative, and positive. In case of emergence only negative or only positive mistakes operation of the machine becomes im-possible as there will be a consecutive accumulation of mistakes. As a result of experimental data processing for stable process of weaving and the invariable diameter of basis threads winding of threads it is revealed that the random error of giving is set up as linear function of the accidental length having normal distribution. Measurements of accidental deviations in giving of a basis by the main regulator allowed to construct a curve of normal distribution of its actual length for one pass of weft thread. The presented curve of distribution of random errors in giving of a basis is the displaced curve of normal distribution of the accidental sizes. Also we define the density of probability of normal distribution of basis giving errors connected with a margin er-ror operation of the main regulator knowing of which allows to plan ways of their decrease that is important for improvement of quality of the produced fabrics.

Evidence-based Assessment

2010 ◽  
pp. 76-98
Author(s):  
John Hunsley ◽  
Eric J. Mash
Keyword(s):  
Decision Making ◽  
Clinical Assessment ◽  
Assessment Process ◽  
Evidence Based ◽  
The Past ◽  
Specific Assessment ◽  
The Many ◽  
Selection Of ◽  
Made In

Evidence-based assessment relies on research and theory to inform the selection of constructs to be assessed for a specific assessment purpose, the methods and measures to be used in the assessment, and the manner in which the assessment process unfolds. An evidence-based approach to clinical assessment necessitates the recognition that, even when evidence-based instruments are used, the assessment process is a decision-making task in which hypotheses must be iteratively formulated and tested. In this chapter, we review (a) the progress that has been made in developing an evidence-based approach to clinical assessment in the past decade and (b) the many challenges that lie ahead if clinical assessment is to be truly evidence-based.

scholarly journals Effect of blast loading and resulting progressive failure of a cable-stayed bridge

2021 ◽  
Vol 3 (3) ◽  
Author(s):  
Ravi Mudragada ◽  
S. S. Mishra
Keyword(s):  
Progressive Failure ◽  
Blast Resistance ◽  
Progressive Collapse ◽  
Building Structures ◽  
Structural Elements ◽  
Blast Loads ◽  
Cable Stayed Bridge ◽  
Bridge Performance ◽  
Cable Stayed Bridges

AbstractMany researchers have carried out experimental and numerical investigations to examine building structures’ response to explosive loads. Studies of bridges subjected to blast loads are limited. Hence, in this study, we present a case study on a cable-stayed bridge, namely, Charles River Cable-Stayed Bridge-Boston, to assess its robustness and resistance against the progressive collapse resulting from localized failure due to blast loads. Three different blast scenarios are considered to interpret the bridge performance to blast loads. To monitor the progressive failure mechanisms of the structural elements due to blast, pre-defined plastic hinges are assigned to the bridge deck. The results conclude that the bridge is too weak to sustain the blast loads near the tower location, and the progressive collapse is inevitable. Hence, to preserve this cable-stayed bridge from local and global failure, structural components should be more reinforced near the tower location. This case study helps the designer better understand the need for blast resistance design of cable-stayed bridges.

Design and topological optimization of rear pressure bulkhead for a typical aircraft

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Marshal Thakran ◽  
Meenakshi ◽  
Jitender Sharma ◽  
Charles Gilbert Martin
Keyword(s):  
Numerical Analysis ◽  
Significant Influence ◽  
Design Methodology ◽  
Structural Integrity ◽  
Topological Optimization ◽  
Content Type ◽  
Iterative Design ◽  
Practical Implications ◽  
Insight Into ◽  
Selection Of

Purpose The purpose of this paper is to evaluate the model of a rear pressure bulkhead with different design optimizations to meet the pressurized cabin requirements of an aircraft. Design/methodology/approach This paper presents the results of the static analysis of a dome-shaped rear pressure bulkhead model designed in Catia-v5. Numerical analysis of model meshed in hyper-mesh and solved using Opti-Struct for iterative design optimizations. Findings All the iterative models are analyzed at 9 Psi. Rear pressure bulkhead designed with L-section stringer shows better results than the model optimized with T-section stringer for the same thickness. The model optimized with L-shaped stinger also reduces the weight of the bulkhead without affecting the structural integrity. Practical implications It has been concluded in this paper that the selection of specific shapes of the stringers shows a significant influence on weight reduction. Originality/value This paper provides a topical, technical insight into the design and development of a rear pressure bulkhead. It also outlines the future development of dome-shaped rear pressure bulkhead.

GIS Based Multi-Criteria decision support system and machine learning for Hospital Site Selection case study Oran - Algeria

2022 ◽  
Vol 14 (1) ◽  
pp. 0-0
Keyword(s):  
Site Selection ◽  
Decision Makers ◽  
Analysis Method ◽  
Automatic Learning ◽  
Hospital Site ◽  
Set Up ◽  
High Level ◽  
Selection Of ◽  
The Ideal

The selection of hospital sites is one of the most important choice a decision maker has to take so as to resist the pandemic. The decision may considerably affect the outbreak transmission in terms of efficiency , budget, etc. The main targeted objective of this study is to find the ideal location where to set up a hospital in the willaya of Oran Alg. For this reason, we have used a geographic information system coupled to the multi-criteria analysis method AHP in order to evaluate diverse criteria of physiological positioning , environmental and economical. Another objective of this study is to evaluate the advanced techniques of the automatic learning . the method of the random forest (RF) for the patterning of the hospital site selection in the willaya of Oran. The result of our study may be useful to decision makers to know the suitability of the sites as it provides a high level of confidence and consequently accelerate the power to control the COVID19 pandemic.

A New Approach to Drug Discovery

2012 ◽  
Vol 17 (4) ◽  
pp. 542-549 ◽  
Author(s):  
Maria Cândida Monteiro ◽  
Mercedes de la Cruz ◽  
Juan Cantizani ◽  
Catalina Moreno ◽  
José R. Tormo ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Antifungal Activity ◽  
High Throughput Screening ◽  
Low Cost ◽  
Pharmacological Action ◽  
Natural Extracts ◽  
Microbial Extracts ◽  
Set Up ◽  
Microtiter Assay ◽  
Selection Of

Natural products are an inexhaustible source for drug discovery. However, the validation and selection of primary screening assays are vital to guarantee a selection of extracts or molecules with relevant pharmacological action and worthy of following up. The assay must be rapid, simple, easy to implement, and produce quick results and preferably at a low cost. In this work, we developed and validated a colorimetric microtiter assay using the resazurin viability dye. The parameters of the resazurin method for high-throughput screening (HTS) using natural extracts against Aspergillus fumigatus were optimized and set up. The extracts plus RPMI-1640 modified medium containing the spores and 0.002% resazurin were added per well. The fluorescence was read after 24 to 30 h of incubation. The resazurin proved to be as suitable as Alamar Blue for determining the minimal inhibitory concentration of different antifungals against A. fumigatus and effective to analyze fungicidal and fungistatic compounds. An HTS of 12 000 microbial extracts was carried out against two A. fumigatus strains, and 2.7% of the extracts displayed antifungal activity. Our group has been the first to use this methodology for screening a collection of natural extracts to identify compounds with antifungal activity against the medically important human pathogen A. fumigatus.

scholarly journals Coriolis effects on the elliptical instability in cylindrical and spherical rotating containers

2007 ◽  
Vol 585 ◽  
pp. 323-342 ◽  
Author(s):  
M. LE BARS ◽  
S. LE DIZÈS ◽  
P. LE GAL
Keyword(s):  
Growth Rates ◽  
Close Agreement ◽  
Unstable Mode ◽  
Quantitative Agreement ◽  
Fixed Rate ◽  
Elliptical Instability ◽  
Normal Mode Theory ◽  
Set Up ◽  
First Time ◽  
Selection Of

The effects of the Coriolis force on the elliptical instability are studied experimentally in cylindrical and spherical rotating containers placed on a table rotating at a fixed rate $\tilde{\Omega}^G$. For a given set-up, changing the ratio ΩG of global rotation $\tilde{\Omega}^G$ to flow rotation $\tilde{\Omega}^F$ leads to the selection of various unstable modes due to the presence of resonance bands, in close agreement with the normal-mode theory. No instability occurs when ΩG varies between −3/2 and −1/2 typically. On decreasing ΩG toward −1/2, resonance bands are first discretized for ΩG<0 and progressively overlap for −1/2 ≪ ΩG < 0. Simultaneously, the growth rates and wavenumbers of the prevalent stationary unstable mode significantly increase, in quantitative agreement with the viscous short-wavelength analysis. New complex resonances have been observed for the first time for the sphere, in addition to the standard spin-over. We argue that these results have significant implications in geo- and astrophysical contexts.

Sign in / Sign up

Export Citation Format

Share Document