scholarly journals Potential of Carica papaya Seed-Derived Bio-Coagulant to Remove Turbidity from Polluted Water Assessed through Experimental and Modeling-Based Study

2021 ◽  
Vol 11 (12) ◽  
pp. 5715
Author(s):  
Amir Hariz Amran ◽  
Nur Syamimi Zaidi ◽  
Achmad Syafiuddin ◽  
Loh Zhang Zhan ◽  
Muhammad Burhanuddin Bahrodin ◽  
...  
Keyword(s):  
Functional Groups ◽  
Carica Papaya ◽  
Polluted Water ◽  
Spectroscopy Analysis ◽  
Coagulation Activity ◽  
Turbidity Removal ◽  
Papaya Seeds ◽  
Carica Papaya Seed ◽  
The Fourier Transform ◽  
Central Composite

It is important to develop renewable bio-coagulants to treat turbid water and efficient use of these bio-coagulants requires process optimization to achieve robustness. This study was conducted to optimize the coagulation process using bio-coagulant of deshelled Carica papaya seeds by employing response surface methodology (RSM). This bio-coagulant was extracted by a chemical-free solvent. The experiments were conducted using the Central Composite Design (CCD). Initially, the functional groups and protein content of the bio-coagulant were analyzed. The Fourier Transform Infrared Spectroscopy analysis showed that the bio-coagulant contained OH, C=O and C-O functional groups, which enabled the protein to become polyelectrolyte. The highest efficiency of the bio-coagulant was obtained at dosage of 196 mg/L, pH 4.0 and initial turbidity of 500 NTU. At the optimum conditions, the bio-coagulant achieved 88% turbidity removal with a corresponding 83% coagulation activity. These findings suggested that the deshelled Carica papaya seeds have potential as a promising bio-coagulant in treating the polluted water.

scholarly journals Turbid Water Treatment Using Deshelled Carica papaya Seed: Analysis Via Factorial Design

2021 ◽  
Vol 12 (6) ◽  
pp. 7787-7795
Keyword(s):  
Water Treatment ◽  
Carica Papaya ◽  
Turbid Water ◽  
Turbidity Removal ◽  
Coagulant Dosage ◽  
Natural Coagulants ◽  
Operational Factors ◽  
Papaya Seeds ◽  
Carica Papaya Seed ◽  
Papaya Seed

Natural coagulants are proven to be a good alternative to conventional coagulants with the removal of various pollutants and are environmentally friendly. Despite its advantages, the least studies were carried out on local agro-wastes such as papaya seeds as natural coagulants concerning different operational factors. The study analyzes the main and interactions effect between the coagulant dosage, initial turbidity, and pH on deshelled Carica papaya seeds for turbid water treatment. A 2-level factorial design was used to investigate the main and interaction effects of the main operational factors, viz. coagulant dosage (50-200 mg/L), pH (3-7), and initial turbidity (100-500 NTU) on the turbidity removal of the synthetic turbid water. Based on individual performance, the results suggested that initial turbidity and pH are the most significant factors among the investigated operational factors. In combination, all interactions are significant, but the interaction between initial turbidity and pH is most significant, with 97.2% turbidity removal. Upon application of Carica papaya seed as a natural coagulant in water and wastewater treatment, these operating variables and their interactions are best to be considered.

scholarly journals Gastroprotective effect of ethanol extract of carica papaya seed on rats induced rifampicin and isoniazid

2021 ◽  
Vol 12 (2) ◽  
pp. 1506-1512
Author(s):  
Elviyanti ◽  
Nyoman Ehrich Lister I ◽  
Edy Fachrial
Keyword(s):  
Carica Papaya ◽  
Ethanol Extract ◽  
Potential Effect ◽  
First Line Therapy ◽  
Gastroprotective Effect ◽  
Long Time ◽  
Papaya Seeds ◽  
Group 2 ◽  
Carica Papaya Seed ◽  
Ph Level

The first-line therapy for tuberculosis is Rifampicin, in combination with Isoniazid (INH), Ethambutol (ETB), and Pyrazinamide (PZA). The side effects of TB drugs that may arise if the drug use for a long time include hepatotoxicity and gastrointestinal disturbances. Carica papaya seeds has a potential effect to prevent the gastrointestinal distrubances caused by rifampicin and isoniazid. This study aimed to evaluate the gastroprotective effect of carica papaya seeds on rats induced rifampicin and isoniazid. Experimental design group was divided into 8 group, including normal, negative 1 (rif 50 mg/kgbb), negative 2 (IN 50 mg/kgbw), negative 3 (rif and inh 50 mg/kgbw), positive 1 (rif and inh 50 mg/kgbw + cimetidtine 18 mg/kgbw), group 1(rif and inh 50 mg/kgbw + EECP 100 mg/kgbb) +, group 2 (rif and inh 50 mg/kgbw + EECP 300 mg/kgbb), group 3 (rif and inh 50 mg/kgbw + EECP 500 mg/kgbb). Rifampicin, isoniazid, and EECP was given 20 days. The result showed that rifampicin and isoniazid induced alteration gastric organ, histopathology of the negative group also showed alteration and also decreased pH level.

scholarly journals Deshelled Carica papaya Seeds as Natural Coagulant for Improvement Quality of River Water

2021 ◽  
Vol 50 (6) ◽  
pp. 1521-1529
Author(s):  
Amir Hariz Amran ◽  
Nur Syamimi Zaidi ◽  
Khalida Muda ◽  
Muhammad Burhanuddin Bahrodin ◽  
Wai Loan Liew
Keyword(s):  
Surface Charge ◽  
Protein Content ◽  
River Water ◽  
Functional Groups ◽  
Carica Papaya ◽  
Antibacterial Properties ◽  
Class Iii ◽  
Natural Coagulant ◽  
Papaya Seeds

This study evaluated the efficiency of deshelled papaya seeds as the natural coagulant in improving quality of river water. The deshelled papaya seeds biomass was mainly characterized for functional groups using FTIR, surface charge and protein content. Coagulation and flocculation tests were conducted using batch test for various dosages and pH values. The optimum dosage and pH were then tested in treating river of Class III to Class V. The functional groups in deshelled papaya seeds were O-H, C=O and C-O groups. The surface charge and protein content was +0.4 meq/g and 363 mg/g, respectively. The deshelled papaya seeds coagulant was able to remove turbidity up to 87.6 and 88.3% for river of Class III and Class IV, respectively, as well as 57.6 and 62.1% of total coliform and escherichia coli, respectively, from Class III river at dosage 196 mg/L and pH 4. This study demonstrated that the deshelled Carica papaya seeds-derived coagulant is capable in treating common pollutants of river and simultaneously shows antibacterial properties.

Convective drying of papaya seeds (Carica papaya L.) and optimization of oil extraction

2016 ◽  
Vol 85 ◽  
pp. 221-228 ◽  
Author(s):  
Daniel Padoin Chielle ◽  
Daniel Assumpção Bertuol ◽  
Lucas Meili ◽  
Eduardo Hiromitsu Tanabe ◽  
Guilherme Luiz Dotto
Keyword(s):  
Carica Papaya ◽  
Oil Extraction ◽  
Convective Drying ◽  
Papaya Seeds

scholarly journals Anealisis Uji Pendahuluan Aktivitas Antikanker Ekstrak Biji Pepaya (Carica papaya L) dengan Metode BSLT

2019 ◽  
Vol 4 (1) ◽  
pp. 7-10
Author(s):  
Ninik Mas Ulfa ◽  
Galuh Gondo Kusumo ◽  
Ilil Maidatuz Zulfa
Keyword(s):  
Anticancer Activity ◽  
Carica Papaya ◽  
Tropical Plant ◽  
Preliminary Study ◽  
Papaya Seeds ◽  
Preliminary Research ◽  
Papaya Seed

ABSTRAKTumbuhan pepaya (carica papaya L) merupakan tumbuhan tropis yang banyak terdapat di Indonesia. Tumbuhan ini mempunyai banyak manfaatnya mulai dari buah, biji, hingga daunnya. Penelitian pendahuluan menyebutkan buah pepaya mengandung alkaloid dan flavonoid yang berkhasiat sebagai antikanker. Senyawa BenzylIsothiocyanat diketahui banyak terdapat pada biji dan buah pepaya yang sudah matang. Kandungan BenzylIsothiocyanat mempunyai khasiat sebagai antikanker. Pemanfaatan limbah biji pepaya pada penelitian ini untuk membuktikan aktivitas Benzyl-Isothiacyanat yang berkhasiat sebagai antikanker. Penelitian ini merupakan penelitian pendahuluan untuk menganalisis aktivitas antikanker dari Ekstrak kental biji pepaya dengan menggunakan metode BSLT. Konsentrasi ekstrak kentak yang digunakan yaitu 100 ppm, 200 ppm dan 300 ppm masing-masing diujikan pada 10 larva udang dalam air laut. Diperoleh hasil rata-rata kematian pada konsentrasi 100 ppm adalah 4,3, 200 ppm adalah 5,3 dan 300 ppm adalah 6,7. Hasil regresi linearitas menunjukkan aktivitas antikaker pada uji BSLT dari Ekstrak kental biji pepaya dengan LC50 sebesar 163,89 ppm. Dengan demikian ekstrak kental biji pepaya tersebut berpotensi untuk dikembangkan sebagai bahan antikanker alamiKata kunci: Aktivitas antikanker, Carica papaya, metode BSLT.ABSTRACTPapaya plant (carica papaya L) is a tropical plant that is widely found in Indonesian. This plant has many benefits ranging from fruit, seeds, to leaves. Preliminary research says papaya fruit contains alkaloids andflavonoids which are efficacious as anticancer. Benzyl-Isothiocyanat compounds are known to be widely found in ripe papaya seeds and fruit. The content of Benzyl-Isothiocyanat has properties as an anticancer. The use of papaya seed waste in this study is to prove the activity of Benzyl-Isothiacyanat which is efficacious as an anticancer. This research is a preliminary study to analyze the anticancer activity of thick papaya seeds using the BSLT method. The concentrations of used fart extracts were 100 ppm, 200 ppm and 300 ppm each tested on 10 shrimp larvae in seawater. The results of the average mortality at concentrations of 100 ppm were 4.3, 200 ppm were 5.3 and 300 ppm was 6.7. The linearity regression results showed the anticaker activity in the BSLT test from the thick extract of papaya seeds with LC50 of 163.89 ppm. Thus the thick extract of papaya seeds has the potential to be developed as a natural anticancer material.Key Words : Anticancer activity, BSLT method, Carica papaya.

scholarly journals Methanolysis of Carica papaya Seed Oil for Production of Biodiesel

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Foluso O. Agunbiade ◽  
Tolulope A. Adewole
Keyword(s):  
Specific Gravity ◽  
Carica Papaya ◽  
Seed Oil ◽  
Fossil Fuel ◽  
Biodiesel Production ◽  
Copper Strip ◽  
Saponification Value ◽  
Biodiesel Synthesis ◽  
Carica Papaya Seed ◽  
Papaya Seed

The future of fossil fuel sources of energy has necessitated the need to search for renewable alternatives. Thus, Carica papaya seed oil (CPSO) was employed as feedstock for the production of biodiesel by methanolysis. The seed was obtained locally, dried, and extracted with n-hexane. The CPSO was analyzed for specific gravity, viscosity, iodine value, and saponification value, among others using standard methods. The oil was transesterified by two-stage catalysis with oil to methanol mole ratio of 1 : 9. The biodiesel produced was subjected to standard fuel tests. The seed has an oil yield of 31.2% which is commercially viable. The kinematic viscosity of the oil at 313 K was 27.4 mm2s−1 while that of Carica papaya oil methylester (CPOME) was reduced to 3.57 mm2s−1 and the specific gravity was 0.84 comparable with other seed-oil biodiesels and number 2 diesel. Other oil properties were compared favourably with seed oils already documented for biodiesel synthesis. CPOME’s cloud and pour points were 275 K and 274 K, respectively, and relatively higher than other biodiesels and number 2 diesel. CPOME exhibits moderate corrosion of copper strip. The methanolysis improved the fuel properties of the CPOME similar to other biodiesels. CPSO therefore exhibits a potential for biodiesel production.

Effect of Ethanolic Extract of Carica Papaya seeds in Drug-Induced Acute Nephrotoxicity

2021 ◽  
Vol 15 (11) ◽  
pp. 2951-2953
Author(s):  
Sameer Ahmed ◽  
Muhammad Tahir ◽  
Attiya Munir ◽  
Amtul Hafeez ◽  
Sher Afghan Khan ◽  
...  
Keyword(s):  
Carica Papaya ◽  
Ethanolic Extract ◽  
Control Group ◽  
Standard Diet ◽  
Serum Urea ◽  
Once Daily ◽  
Group Iii ◽  
Group I ◽  
Papaya Seeds ◽  
Group Ii

Background: Nephrotoxicity is characterized by raised serum urea and creatinine levels and kidneys being one of the primary organs of drug concentration and excretion are vulnerable to many widely used marketed drugs, including anti-cancer drugs, antibiotics, immunosuppressants, and radio contrast agents, are nephrotoxic. Aim: To determine the nephroprotective effect of ethanolic extract of Carica papaya seeds in Aminoglycoside induced acute nephrotoxicity. Study design: Quasi Experimental study. Methodology: Thirty Sprague Dawley rats were sub divided into 3 groups i.e., I, II and III with 10 rats in each group. Group II and III were administered Aminoglycoside drug; Gentamycin in 80 mg/kg) via intraperitoneal route once daily for 5 consecutive days to induce acute nephrotoxicity. At day 6, nephrotoxicity was confirmed by measuring serum urea and creatinine. Ethanolic extract of Carica papaya seeds (1000 mg/kg) was started once daily through oral route in group III for 5 consecutive days to see the nephroprotective effects of seed extract after causing acute kidney injury. All animals were given standard diet pellets manufactured at NIH. Results: Mean serum urea and creatinine for Group I (Control Group) at day 0 were 24.90 mg/dL ± 1.633 and .750 mg/dL ± .0619 respectively. Mean serum urea and creatinine for Group II (Disease Control Group) was 81.00 mg/dL ± 1.247 and 1.980mg/dL ± .0467 at day 6th. This suggested induction of nephrotoxicity by Gentamycin. Mean serum urea and creatinine for Group III (Ethanolic Extract Treated Group) at 11 day was 72.40mg/dL± .991 and 1.680 mg/dL± .0467 after 5 days treatment with ethanolic extract of Carica papaya seeds. Conclusion: We concluded that ethanolic extract of Carica papaya seeds has significant nephroprotective effects on Aminoglycoside induced acute nephrotoxicity in rats. Keywords: COVID-19, Vaccination, Awareness and Adverse Effects

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