Evaluation of Occupational Exposure Risk for Employees Working in Dynamic Olfactometry: Focus on Non-Carcinogenic Effects Correlated with Exposure to Landfill Emissions

Atmosphere ◽  
2021 ◽  
Vol 12 (10) ◽  
pp. 1325
Author(s):  
Elisa Polvara ◽  
Baharak Essna ashari ◽  
Laura Capelli ◽  
Selena Sironi

This work aims to evaluate the non-carcinogenic health effects related to landfill odor emissions, therefore focusing on workers involved in dynamic olfactometry. Currently, the most common technique to quantify odor emissions is dynamic olfactometry, a sensorial analysis involving human assessors. During the analysis, assessors are directly exposed, at increasing concentrations, to odor samples, and thus to the hazardous pollutants contained therein. This entails the need to estimate the associated exposure risk to guarantee examiners’ safety. Therefore, this paper evaluates the exposure risk for olfactometric examiners to establish the minimum dilution level to be adopted during the analysis of landfills’ odorous samples to guarantee panelists’ safety. For this purpose, an extensive literature review regarding the pollutants emitted by landfill odor sources was conducted, comparing compounds’ chemical concentrations and threshold limit values (TLVs) to calculate the Hazard Index (HI) and thus establish a minimum dilution value. The data collected indicate that a non-negligible non-carcinogenic risk exists for all landfill emissions considered. However, from the data considered, the minimum dilution factor to be adopted is lower than the typical odor concentration observed for these sources. Therefore, the olfactometric analysis of landfill samples can be generally conducted in safe conditions.

2020 ◽  
Vol 12 (1) ◽  
pp. 568-579
Author(s):  
Liping Mo ◽  
Yongzhang Zhou ◽  
Gnanachandrasamy Gopalakrishnana ◽  
Xingyuan Li

AbstractSihui city (South China) is much affected by nasopharyngeal carcinoma (NPC). To investigate the relationships between the toxic metals in soil and NPC incidence in Sihui, 119 surface soil samples were collected from agricultural fields and analyzed. The soil As–Cr contents in Longjiang (high-incidence area) are significantly lower than those in Weizheng and Jianglin (low-incidence areas), whereas the soil Pb content in Longjiang is significantly higher than that in Weizheng. The Nemerow pollution indices (PIN) of soils decrease in the order of Jianglin > Weizheng > Longjiang. The enrichment factor (EF) of Cd indicates that the Cd enrichment is contributed by human activities. Potential toxic metal-related ecological risk values decrease in the order of Jianglin > Weizheng > Longjiang. The mean hazard index (HI) value of Longjiang was lower than those of Weizheng and Jianglin. There are no adverse noncarcinogenic health effects of soil toxic metals to adults in the study areas. Carcinogenic risks of As and Cr via ingestion and dermal contact and total carcinogenic risk are within the warning range, from 10−6 to 10−4. Hence, we suggest that toxic metals in the soil may not be major geochemical carcinogenic factors of high NPC incidence in Sihui.


2020 ◽  
Vol 5 (1) ◽  
pp. 166-175
Author(s):  
Fatima Haque ◽  
Yi Wai Chiang ◽  
Rafael M. Santos

AbstractCalcium- and magnesium-rich alkaline silicate minerals, when applied to soil, can aid in carbon dioxide sequestration via enhanced weathering. The weathering of these silicate minerals is also associated with the release of heavy metals such as Ni and Cr, depending on the composition of the parent rock, and also labile Si. This paper critically analyses the risk associated with the release of Ni, Cr, and Si from alkaline silicate minerals as a result of enhanced weathering to evaluate its potential to be applied as a soil amendment. Based on the available data in the literature, this study evaluates the soil contamination level and quantifies the risk these elements pose to human health as well as the environment. To assess these potential threat levels, the geoaccumulation index was applied, along with the method recommended by the US Environmental Protection Agency for health risk assessment. The main findings of this study indicate the potential release of Ni, Cr, and Si to exceed the soil quality guideline value. The geochemical index suggests that the analyzed samples are in the class 0–3 and represents sites that lie between uncontaminated zones to highly contaminated zones. The hazard index value for Ni and Cr is greater than unity, which suggests that Ni and Cr release poses a non-carcinogenic risk. The probability of labile Si concentration in the soil to exceed the critical value is found to be 75%.


2021 ◽  
pp. 096032712199321
Author(s):  
M Charehsaz ◽  
S Helvacıoğlu ◽  
S Çetinkaya ◽  
R Demir ◽  
O Erdem ◽  
...  

In this study, the level of arsenic (As), lead (Pb) and cadmium (Cd) and also essential elements in beer samples consumed in Turkey were investigated using the inductively coupled plasma mass spectrometry (ICP-MS) method. The heavy metal-induced non-carcinogenic and carcinogenic risks were calculated. For essential elements, the calculated estimated daily intake of iron (Fe), copper (Cu), selenium (Se) and cobalt (Co) from beer consumption were compared with their toxicity reference values. Tukey post-hoc test showed that As was found at a significantly higher level when compared to Pb. Also, a significant correlation was found between As level and alcohol by volume percent. All samples had a hazard quotient and hazard index <1, indicating no non-carcinogenic risk from exposure to single or multiple heavy metals. Some samples exceeded the threshold limit of acceptable cancer risk for As in the high beer consumer group. This assessment showed that in addition to health implications based on the alcohol content of beer, there might be a carcinogenic risk associated with the heavy metals content of these beverages.


2021 ◽  
Vol 2 (6) ◽  
Author(s):  
Leatitiah Namubiru ◽  
Denis Male ◽  
Ivan Mukisa Muzira ◽  
Yusuf Byenkya Byaruhanga

Previous studies have reported the presence of aflatoxins (AFB1, AFB2, AFG1 and AFG2), heavy metals (As, Cd and Pb) and organochlorine pesticide residues (OCPs) in rice sold in Uganda. However, the potential health effects associated with consumption of rice have not been evaluated. The aim of this study was to evaluate the health risk of consuming rice sold in Uganda. A total of 45 packed and 30 open traded rice samples were randomly collected from retail outlets in the main rice trading areas of Uganda. Rice was analysed for AFB1, AFB2, AFG1 and AFG2, As, Cd, Pb and OCPs using AOAC standard methods. Dietary exposure of the consumers to contaminants was assessed using the estimated daily intake (EDI). The Hazard index (HI) and the incremental lifetime cancer risk (ILCR) were determined to define the non-carcinogenic and carcinogenic risk from contaminants, respectively. The potency of liver cancer cases in Uganda was 1.02E-5 and 1.05E-5 adults/year/100,000, and 6.50E-4 and 6.72E-5 infants /year/100,000 for open traded and packed rice, respectively. The values obtained for the ILCR for Arsenic detected in rice were 1.14E-2 and 7.28E-2 for adults and infants, respectively. The ILCR of all detected OCPs in adults and infants were higher than 1.0E-4, in both open traded and packed rice. This study established a potential carcinogenic risk from consumption of rice sold in Uganda in both infants and adults at the current level of contamination and consumption rate. Establishment of a monitoring system along the entire rice value chain; enforced by a national regulatory body can provide timely feedback on the levels of contamination and the progress in reducing the contamination burden.


2020 ◽  
Vol 19 (1) ◽  
pp. 43-56
Author(s):  
Veerapas Na Roi-et ◽  
◽  
Supawat Chaikasem ◽  

Emission of volatile organic compounds (VOCs) from photocopiers was investigated to assess the potential health impacts on inhalation exposure to VOCs. VOCs samples were collected during working hours using SKC VOCs 575 series passive sample. Twenty-one quantified VOCs were measured and analyzed by GC-MS/MS. The results showed that the total VOCs concentration emitted in the photocopy centers A and B were 2.29×104 and 2.32×104 µg/m3, respectively. The highest detected chemical was trans-1,2-Dichloroethene at about 2.18×104 (photocopy center A) and 2.15×104 µg/m3 (photocopy center B (The results reveal that the non-carcinogenic risk for inhalation exposure to m-Xylene, p-Xylene, and trans-1,2-Dichloroethene were in the range 0.94-1.53 and 1.19-1.79 and 51.54-52.23, respectively, resulting in the hazard index (HI) of non-carcinogenic VOCs in total being greater than 1.0. This indicated that the cumulative effects of inhalation exposure to VOCs at low concentrations should be of concern, even though it does not exceed the occupational exposure limits and Threshold Limit Values-Time Weighted Average for the mixtures (TLV-TWAmix). Plants display a greener solution to reduce indoor air pollution. The bio-concentration levels of total VOCs in Epipremnum aureum were noted as 74.71 to 174.42, signifying that E. aureum is effective for removal of VOCs naturally and sustainably.


Proceedings ◽  
2018 ◽  
Vol 6 (1) ◽  
pp. 9
Author(s):  
Suryana Fomina ◽  
Nataliya Stepanova ◽  
Ilyuza Galimullina ◽  
Lyudmila Obukhova

The analysis of the intake of chemicals such as cadmium (Cd), lead (Pb), arsenic (As), and mercury (Hg) in the diet of children aged 3–6 years from the city of Kazan for the periods 2007–2010 and 2011–2014 was carried out. The study of actual child nutrition was performed by questionnaire and time-weight methods. The calculation of daily doses was made with the account of regional exposure factors at the 95th percentile level. The non-carcinogenic risk from the exposure to methylmercury with basic food groups at the level of the 95th perc made 3.89 and 3.33 for both periods, 10.67—for arsenic in the first period, being unacceptable (hazard quotient (HQ) > 1). In 2007–2010, the central nervous system (CNS), the hormone system (HS), the immune system (IS), and the development (hazard index (HI) = 15.75, 12.87, 11.72, and 4.03) were exposed to the highest toxic effect, and in 2011–2014, the CNS and the development (HI = 4.02 and 3.98). The risk of developing non-carcinogenic effects for these systems (64%–91%) was mainly due to contamination of foods with As for the first period, and to the intake of Pb (46%–57%) for the second period. The value of the total individual carcinogenic risk (ICR Cd, Pb, As), for the second period 1.69 × 10 5 corresponded to the maximum allowable level. In 2007–2010, the total ICR was 2.45 × 10 4 which is an unacceptable level for the general population. The major contribution to the total ICR due to the intake of contaminated foods was made by As (92.55%) in the first period, and by Cd (79.93%) in the second period. The peculiarities of the child body (the amount of chemicals ingested per kilogram of body weight is higher in children than in adults) determine the potential risk and are responsible for high vulnerability on exposure to chemicals and the development of adverse effects.


2019 ◽  
Vol 29 (8) ◽  
pp. 1137-1154
Author(s):  
Chukwujindu M.A. Iwegbue ◽  
Nnamdi Nwose ◽  
Francis E. Egobueze ◽  
Eze W. Odali ◽  
Godswill O. Tesi ◽  
...  

This study concerns an assessment of indoor dust from printing press, car spray painting and metal design workshops, with the aim of evaluating the occupational risk arising from exposure to metals present in the dust. The levels of Cd, Pb, Cr, Ni, Cu, Co, Mn, Zn and Fe in the dust samples were quantified by means of atomic absorption spectrometry. The concentrations of metals (mg kg−1) in the indoor dust from these workplace environments varied from <0.003–208 for Cd, 26.5–1530 for Pb, 7.80–346 for Cr, 10.5–490 for Ni, 32.0–1915 for Cu, 3.50–232 for Co, 169–20,300 for Zn, 87.5–7260 for Mn and 8900–661,000 for Fe. The hazard index values were above one for different age groups except for the exposure of teenagers and adults to metals in dusts in the printing press studios and car spray painting workshops. The carcinogenic risk for all age groups relating to human contact with metals (Cd, Pb, Cr and Ni) in dust from these workplace environments via three exposure pathways: oral ingestion, inhalation and dermal contact, were above the safe level of 1.0 × 10−6 but not up to the level (1.0 × 10−4) that requires remedial action.


2019 ◽  
Vol 82 (5) ◽  
pp. 785-795 ◽  
Author(s):  
YADOLAH FAKHRI ◽  
RAHEB GHORBANI ◽  
MAHMOUD TAGHAVI ◽  
HASSAN KERAMATI ◽  
NAZAK AMANIDAZ ◽  
...  

ABSTRACTThis meta-analysis was designed to review the published reports regarding the concentration and/or prevalence of aflatoxin M1 (AFM1) in human breast milk in Iran. The carcinogenic risk for Iranian infants consuming this milk was estimated with the hazard index. The PubMed and Scopus databases and the Scientific Information Database were screened for relevant studies between 1995 and 2017, and 11 of the 112 collected studies were included in the systematic review and meta-analysis. The mean (95% confidence interval) concentration of AFM1 was 5.85 ng/L (4.54 to 7.15 ng/L), which was lower than the European Union standard (25 ng/L). The mean prevalence of AFM1 in breast milk in Iran was 42% (11 to 77%). The estimated daily intakes for male and female infants were 0.02 to 5.57 ng/kg and 0.02 to 3.68 ng/kg of body weight per day, respectively. The rank order of estimated daily intake for both male and female infants according to age was 1 week &gt; 1 month &gt; 6 months &gt; 12 months. The hazard index for all age groups of infants in all provinces in Iran was less than 1. Therefore, infants in Iran were not considered at carcinogenic risk from AFM1 in human breast milk.


2017 ◽  
Vol 25 (2) ◽  
pp. 127-144
Author(s):  
Mohamed Nouri ◽  
Taoufik El Rasafi ◽  
Abdelmajid Haddioui

Abstract The concentrations of metals were determined in soil samples collected in Ait Ammar (Oued Zem, Morocco). The mean Cd, Cr, Cu, Fe, Pb and Zn contents in the mining topsoil samples were: 2.12, 135, 34.9, 214, 9.13 and 90.8 mg kg−1, respectively. Human health risks developed from metal ingestion, dermal absorption and inhalation of soils were also evaluated. For non-carcinogenic risks, united hazard index (HI) values for children surpassed the safe level (HI=1) for Cr (13.1). Values for HI in adults (1.74) also surpassed the safe level for Cr. The HI values for Pb and Cd for children were 0.69 and 0.68, respectively. Cancer risk due to Cr surpassed the tolerable range (1E-06 to1E-04) for children (1.05E-03) and for adults (1.42E-04). Cancer risks due to Pb and Cd were within acceptable ranges for both children and adults. Furthermore, oral ingestion of soil particles contributed more highly to both carcinogenic and non-carcinogenic risk from Cr than either dermal absorption or inhalation in both children and adults.


2012 ◽  
Vol 66 (7) ◽  
pp. 1399-1406 ◽  
Author(s):  
L. Capelli ◽  
S. Sironi ◽  
R. Del Rosso ◽  
G. Bianchi ◽  
E. Davoli

This paper describes the approach adopted for the evaluation both of the odour impact and of the non-carcinogenic health effects relevant to odours in the city of Terni, Italy. The first part of the study focused on the quantification of emissions by means of dynamic olfactometry and chemical analyses. Dispersion modelling was then applied for the evaluation of citizens' exposure both to odours and to their non-carcinogenic toxicity. The results show that, on one hand, the odour impact is considerable, actually affecting almost the whole city of Terni. On the other hand, the toxic impact, expressed in terms of the Hazard Index (HI), is about three orders of magnitude lower than the level that is expected to bring adverse effects, over a lifetime exposure, for human health.


Sign in / Sign up

Export Citation Format

Share Document