scholarly journals Paraneoplastic Syndromes in Patients with Keratinocyte Skin Cancer

Cancers ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 249
Author(s):  
Christoforos Vlachos ◽  
Chrysanthi Tziortzioti ◽  
Ioannis D. Bassukas

A variety of well-characterized cutaneous paraneoplastic syndromes (PNS) are diagnosed during internal malignancies; however, the spectrum of keratinocyte skin neoplasms (KSC) related to PNS is still obscure. The aim of the present review is to compile and evaluate the literature data on PNS associated with a keratinocyte skin neoplasm (KSC). Employing Pubmed, MEDLINE was searched for KSC-associated PNS reports. Forty relevant entries were assembled, reporting a total of 41 PNS cases associated with a KSC (34 male). No review paper compiling this topic was found. Six distinct PNS entities were identified, and malignancy associated hypercalcemia (MAH; 78%), anemia (10%) and Bazex syndrome (5%) were the most frequently reported among them. 85% of the PNS were reported in association with SCC, 10% with BCC, and the rest with adnexal tumors. The median age of the patients at the time of PNS diagnosis was 58 years (range: five–83 years). In most cases the PNS was diagnosed either concurrently or after the KSC diagnosis. KSC predisposing conditions, as scars (22%) or hidradenitis suppurativa (20%), were reported in >70% of the PNS cases. Most PNS resolved after KSC treatment. In conclusion, PNS of a rather limited spectrum of entities are reported in association with KSC. They also seem to be rare, possibly reflecting a limited capacity of KSC to provoke overt PNS.

2012 ◽  
Vol 87 (2) ◽  
pp. 212-219 ◽  
Author(s):  
Pedro Andrade ◽  
Maria Manuel Brites ◽  
Ricardo Vieira ◽  
Angelina Mariano ◽  
José Pedro Reis ◽  
...  

BACKGROUND: Non-melanoma skin cancer, a common designation for both basal cell carcinomas and squamous cell carcinomas, is the most frequent malignant skin neoplasm. OBJECTIVE: Epidemiologic characterization of the population with Non-melanoma skin cancer. METHODS: Retrospective analysis of all patients diagnosed with Non-melanoma skin cancer based on histopathologic analysis of all incisional or excisional skin biopsies performed between 2004 and 2008 in a Department of Dermatology. RESULTS: A total of 3075 Non-melanoma skin cancers were identified, representing 88% of all malignant skin neoplasms (n=3493) diagnosed in the same period. Of those, 68,3% were basal cell carcinomas. Most Non-melanoma skin cancer patients were female and over 60 years old. Of all Non-melanoma skin cancer, 81,7% (n=1443) were located in sun-exposed skin, and represented 95,1% of malignant skin neoplasms in sun-exposed skin. Non-melanoma skin cancer was the most frequent malignant skin neoplasm in most topographic locations, except for abdomen and pelvis - over 95% of all malignant skin neoplasms in the face, neck and scalp were Non-melanoma skin cancer. Basal cell carcinomas were clearly predominant in all locations, except in upper and lower limbs, lower lip and genitals, where squamous cell carcinomas represented respectively 77,7%, 77,4%, 94,7% and 95,3% of the Non-melanoma skin cancers. CONCLUSION: Being the most common skin cancer, Non-melanoma skin cancer should be under constant surveillance, in order to monitor its epidemiologic dynamics, the efficiency of preventive measures and the adaptation of the healthcare resources.


2016 ◽  
Author(s):  
Maya Guglin

The field of mechanical circulatory support is rapidly evolving and new data are published at a rate that can be overwhelming. Last year, we published a review paper entitled “What Did We Learn about VADs in 2014?” That paper was well received – the full text was downloaded over 350 times by the readers around the globe. Encouraged by this, we wrote the present review, where, like before, we summarized some of the publications from 2015 that we think are particularly important.


2017 ◽  
Vol 38 (04) ◽  
pp. 284-291
Author(s):  
Daniel Damiani ◽  
Durval Damiani

AbstractThe present review paper aims to update the definition and classification of cerebral concussion, highlighting its pathophysiological mechanisms. The high prevalence of cerebral concussion in emergency rooms around the world makes it necessary to know its proper management to avoid its late sequelae, which traditionally compromise cognitive aspects of behavior. New evidence on potential neuroprotective treatments is being investigated.


2019 ◽  
Vol 14 (2) ◽  
pp. 223-236
Author(s):  
Stanisław Wieteska ◽  
Małgorzata Jabłońska

This article presents the results of the observation of cases of skin melanomas in Poland. Dermatologists raise the problem of increased sunlight penetration and the unreasonable use of solar radiation. This causes numerous cases of skin cancer. The aim of the article is to signal the threat posed by the depletion of the ozone layer in Poland. The article uses a research method based on an analysis of statistical data on skin cancers, supported by the available research in this area. Studies show that the incidence of skin cancer in Poland in 2007-2016 nearly doubled. Women are more prone than men to skin neoplasms. The mortality rate due to skin melanoma also increased dramatically. In the article, we point to the need of raising awareness of the hazards, and consider the coverage of treatment costs by life insurance as one of the options to protect the health of insured persons. We also raise the problem of prophylaxis on the basis of sunscreen cosmetic products.


2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Vijayalakshmi, K ◽  
C. G. Venkatesha Murthy

The present review paper attempts to present the challenges faced by the caregivers when they assume care giving responsibilities for person/s affected with Alzheimer’s. The experiences in the context of care are not limited with physical and psychological domains alone. Rather care giving for Alzheimer’s involves increased risk of mental, emotional and economic problems as well as due to consequences of care giving that accompanies due to handling such a role. Ultimately the quality of care received by the person with Alzheimer’s and the quality of life of the caregiver becomes imbalance/impaired. Successful execution of the role in care giving brings harmony/balance in life between them in all dimensions of health which is highly essential. Therefore it demands the professionals to help the caregivers to understand about Alzheimer’s disease condition and to handle them based on felt- need to render the best care.


2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Firdevs Ulutaş ◽  
Erdem Çomut ◽  
Veli Çobankara

Systemic sclerosis (SSc) is an uncommon rheumatic disease in which the underlying main histopathologic feature is a thickening of the skin due to excessive accumulation of collagen in the extracellular tissue. Fibrogenesis, chronic inflammation, and ulceration may eventually promote skin neoplasms. Although nonmelanoma skin cancer (NMSC) is the most frequent type, there have been restricted case reports and case series with skin cancers in SSc patients in the literature. Herein, we describe a 78-year-old woman diagnosed with diffuse cutaneous systemic sclerosis thirteen years ago and associated nonspecific interstitial pneumonia that was successfully treated with high cumulative doses of cyclophosphamide. She developed basal cell carcinoma and squamous cell carcinoma of the skin in the follow-up. She is still on rituximab treatment with stable interstitial lung disease as indicated by pulmonary function tests and high-resolution chest computed tomography. To our knowledge and a literature search, this is the first reported patient with SSc with two types of skin cancer. In this review, we also aimed to emphasize the relationship between SSc and skin cancer, and possible risk factors for SSc-related skin cancer.


Author(s):  
Neeru Yadav

Abstract: Six Sigma is a tool which helps industries to control the defects and all other issues which can be possible factors to reduce the growth of the company. It was seen that in large scale industries, the Six Sigma is used form previous decades but when goes to small and medium scale industries, there is lack of implementation of Six Sigma and its tools, so in present review paper, various research papers selected in which small and medium scale industries are selected. In this paper all possible aspects of the Six Sigma is presented in detail. Keywords: Six Sigma, Tools, Small Scale Industries, DMAIC approach, Manufacturing Industries


1977 ◽  
Vol 45 ◽  
pp. 213-228
Author(s):  
M. Mayor

A large amount of work has been devoted to correlations between kinematic properties and spectral types in order to improve our knowledge of stellar populations in our Galaxy and hence to deduce its structure and evolution. The classical results will not be repeated in the present review paper. However, emphasis will be laid on the sometimes contested correlations between age, abundance, kinematic properties and position in the Galaxy.


2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Ana Filipa Duarte ◽  
Bernardo Sousa-Pinto ◽  
Eckart Haneke ◽  
Osvaldo Correia

2018 ◽  
Vol 8 (5-s) ◽  
pp. 47-54
Author(s):  
Tapan K Mahato ◽  
K Sharma

The beneficial medicinal effects of plant materials typically result from the secondary products present in the plant although, it is usually not attributed to a single compound but a combination of the metabolites. The medicinal actions of plants are unique to a particular plant species or group, consistent with the concept that the combination of secondary products in a particular plant is taxonomically distinct.The screening of plants usually involves several approach; ethno botanical approach is one of the common methods that are employed in choosing the plant for pharmacological study. In the present review paper, antimicrobial properties of various medicinal plants were reviewed. The present review deals with the antibacterial activity of various medicinal plants. Keywords: Antimicrobial, Herbal Drugs, WHO, Cup-plate Method, Anti-bacterial Activity.


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