scholarly journals MERTK-Mediated LC3-Associated Phagocytosis (LAP) of Apoptotic Substrates in Blood-Separated Tissues: Retina, Testis, Ovarian Follicles

Cells ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1443
Author(s):  
Marina G. Yefimova ◽  
Celia Ravel ◽  
Antoine D. Rolland ◽  
Nicolas Bourmeyster ◽  
Bernard Jégou
Keyword(s):  
Sertoli Cells ◽  
Tyrosine Kinases ◽  
Acute Inflammation ◽  
The Body ◽  
Tissue Homeostasis ◽  
Ovarian Granulosa Cells ◽  
Males And Females ◽  
Retinal Pigmented Epithelial Cells ◽  
Related Proteins ◽  
Efficient Elimination

Timely and efficient elimination of apoptotic substrates, continuously produced during one’s lifespan, is a vital need for all tissues of the body. This task is achieved by cells endowed with phagocytic activity. In blood-separated tissues such as the retina, the testis and the ovaries, the resident cells of epithelial origin as retinal pigmented epithelial cells (RPE), testis Sertoli cells and ovarian granulosa cells (GC) provide phagocytic cleaning of apoptotic cells and cell membranes. Disruption of this process leads to functional ablation as blindness in the retina and compromised fertility in males and females. To ensure the efficient elimination of apoptotic substrates, RPE, Sertoli cells and GC combine various mechanisms allowing maintenance of tissue homeostasis and avoiding acute inflammation, tissue disorganization and functional ablation. In tight cooperation with other phagocytosis receptors, MERTK—a member of the TAM family of receptor tyrosine kinases (RTK)—plays a pivotal role in apoptotic substrate cleaning from the retina, the testis and the ovaries through unconventional autophagy-assisted phagocytosis process LAP (LC3-associated phagocytosis). In this review, we focus on the interplay between TAM RTKs, autophagy-related proteins, LAP, and Toll-like receptors (TLR), as well as the regulatory mechanisms allowing these components to sustain tissue homeostasis and prevent functional ablation of the retina, the testis and the ovaries.

Schistosomal Appendicitis in Pregnancy

Swiss Surgery ◽  
2002 ◽  
Vol 8 (3) ◽  
pp. 121-122 ◽  
Author(s):  
Halkic ◽  
Abdelmoumene ◽  
Gintzburger ◽  
Mosimann
Keyword(s):  
Acute Appendicitis ◽  
Schistosoma Haematobium ◽  
Acute Inflammation ◽  
The Body ◽  
Parasitic Infections ◽  
Common Complication ◽  
Surgical Infection ◽  
High Prevalence ◽  
Potential Challenge ◽  
In Pregnancy

Acute appendicitis is the most common acute surgical infection during pregnancy. Although usually pyogenic in origin, parasitic infections account for a small percentage of cases. Despite the relatively high prevalence of acute appendicitis in our environment, it is not commonly associated with schistosomiasis. We report here the association of pregnancy and appendicitis caused by Schistosoma haematobium. Schistosomiasis is very common complication of pregnancy in hyperendemic areas. Schistosome egg masses can lodge throughout the body and cause acute inflammation of the appendix, liver and spleen. Congestion of pelvic vessels during pregnancy facilitates passage of eggs into the villi and intervillous spaces, causing an inflammatory reaction. Tourism and immigration make this disease a potential challenge for practitioners everywhere.

Size-At-Age Variability and Sexual Dimorphism of Morphometric Characteristics in the Late Ontogenesis of the Marsh Frog, Pelophylax Ridibundus (Anura, Ranidae), from Terrytory of Crimea

2019 ◽  
Vol 53 (4) ◽  
pp. 325-334
Author(s):  
V. N. Peskov ◽  
N. A. Petrenko ◽  
V. Yu. Reminnyi
Keyword(s):  
Age Groups ◽  
The Body ◽  
Adult Males ◽  
Morphometric Characteristics ◽  
Morphometric Characters ◽  
Mean Values ◽  
Marsh Frog ◽  
Males And Females ◽  
Size At Age ◽  
Linear Body

Abstract We study size-at-age and sexual variability of morphometric characteristics of the marsh frog. According to the size of the body, males were divided into three size-age groups (juvenis, subadultus, adultus), females — into four groups (juvenis, subadultus, adultus, adultus-I). We found that the chronological age of frogs (skeletochronology) does not always correspond to their biological age (size and proportions of the body). We noted that the semi-adult males are reliably larger than females by mean values of 26 studied morphometric characters. Males and females of “adultus” group do not differ by linear body size, significant differences were found in body proportions (7 characters). For the females of “adultus-I” group, the mean values of 26 characters are significantly larger than for “adultus” males. The results of our study showed that with the age of the marsh frog, the level of exhibition, directionality and structure of morphometric sex differences changes.

Further data on Iranian marine nematode diversity, with description of three new Desmodoridae Filipjev, 1922 (Nematoda: Desmodorida) species from the Persian Gulf

Nematology ◽  
2021 ◽  
pp. 1-22
Author(s):  
Azadeh Gharahkhani ◽  
Ebrahim Pourjam ◽  
Daniel Leduc ◽  
Majid Pedram
Keyword(s):  
Persian Gulf ◽  
Buccal Cavity ◽  
First Record ◽  
The Body ◽  
Pharyngeal Bulb ◽  
Close Relationship ◽  
Nematode Diversity ◽  
Males And Females ◽  
The Persian Gulf ◽  
Amphidial Fovea

Summary The Desmodoridae is a diverse and widespread family of free-living nematodes. Here, we provide the first record of the group in the Persian Gulf and describe three new species: Metachromadoroides sinuspersici sp. n., Zalonema iranicum sp. n. and Z. supplementorum sp. n. Metachromadoroides sinuspersici sp. n. is characterised by finely annulated cuticle, short and stout cephalic sensilla, amphidial fovea on cuticular thickening, pharyngeal bulb well developed and partitioned into three sections, absence of precloacal supplements, and presence of 6-8 pairs of rounded postcloacal papillae. Zalonema iranicum sp. n. is characterised by papilliform subcephalic sensilla (best observed with SEM), convex cephalic capsule, large multispiral amphidial fovea with 4-5 turns in both males and females, buccal cavity with one ventrosublateral and two dorsal teeth and posterior body of males with lateral alae extending from the last third of the body to the cloacal aperture and ventral alae extending 1395-2250 μm anterior to the cloacal aperture, and no precloacal supplements. Zalonema supplementorum sp. n. is characterised by four subcephalic sensilla 1-2 μm long, multispiral amphidial fovea with three turns in both males and females, buccal cavity with one dorsal and two ventrosublateral teeth, males with lateral alae present on each side of body from posterior half of body to cloacal aperture, ventral alae extending 942-1257 μm anterior to cloacal aperture, strongly cuticularised spicules 41-43 μm long, and 12-16 precloacal supplements. Near full length SSU and partial D2-D3 LSU sequences are provided for M. sinuspersici sp. n. and Z. iranicum sp. n., and the COI sequence is provided for Z. iranicum. The SSU phylogeny suggests a close relationship between M. sinuspersici sp. n. and Metachromadora and Metachromadoroides species and the monophyly of Zalonema (after currently available data). The LSU phylogeny suggests an affinity between Metachromadoroides and Zalonema with Spirinia and Acanthopharynx, respectively.

Effect of shodhana and shamana chikitsa in mandala kustha (psoriasis): A case study

2019 ◽  
Vol 7 (03) ◽  
Author(s):  
Jyoti Bala Sahu
Keyword(s):  
Body Temperature ◽  
The Body ◽  
Entire Body ◽  
Men And Women ◽  
Remarkable Improvement ◽  
Males And Females ◽  
Regulate Body Temperature ◽  
Old Men

Skin is the largest organ of the body both by surface area and weight. This covers the entire body. The thickness of skin varies considerably over all parts of the body and between young and old, men and women. It helps to regulate body temperature, stores water fat and permit sensation of touch. Psoriasis is a chronic dermatosis characterized by covered by silvery loose scales. Treatment available on contemporary system is not curative but suppressive only. The prevalence of psoriasis is 8%. Prevalence equal in males and females. A case of Mandala Kustha discussed here. Patient successfully treated with Shodhana (Virechana karma) & Shamana Chikitsa. After course of 2 months treatment provides significant relief in Sign and Symptoms. In our classics mentioned Shodhana Chikitsa for Kustha Roga. Considering the sign and symptoms of patient was treated with classical Virechana karma (therapeutic purgation) and Shamana Chikitsa according to line of treatment of Kustha (Psoriasis). Assessment was done on before treatment, after treatment and after follow up of 2 months; pictures were taken before treatment and after treatment. Remarkable improvement was noticed, induration and itching after Virechana treatment.

scholarly journals The occurrence of Contracaecum sp. larvae (Nematoda : Anisakidae) in the catfishClarias gariepinus (Burchell) from Lake Chivero, Zimbabwe

2004 ◽  
Vol 71 (1) ◽  
Author(s):  
M. Barson
Keyword(s):  
Significant Relationship ◽  
Condition Factor ◽  
Clarias Gariepinus ◽  
Parasite Prevalence ◽  
Body Cavity ◽  
The Body ◽  
Nematode Parasites ◽  
Significant Difference ◽  
Third Stage ◽  
Males And Females

Clarias gariepinus were collected from Lake Chivero, Zimbabwe, and examined for nematode parasites from November 2000 to May 2002. Of the 202 specimens collected, 42.6 % were infected with third-stage larvae of Contracaecum sp. in the body cavity. The intensity of the infection was 1-7 worms per fish (mean intensity = 2.2). Seasonal variation in the prevalence of the parasite was not obvious and there was no significant difference in the prevalence of infection between males and females (c2 = 2.228; P > 0.05). No significant relationship between host size and prevalence was established. There was also no significant relationship between intensity and the body condition factor (r = 0.11; P > 0.05). The low parasite prevalence may have been caused by the disruption of the infection cycle since piscivorous birds, which are the final hosts of the parasite, do not feed on C. gariepinus in Lake Chivero.

Pseudancistrus sidereus, a new species from southern Venezuela (Siluriformes: Loricariidae) with a redescription of Pseudancistrus

Zootaxa ◽  
2004 ◽  
Vol 628 (1) ◽  
pp. 1 ◽  
Author(s):  
JONATHAN W. ARMBRUSTER
Keyword(s):  
New Species ◽  
Nasal Bone ◽  
The Body ◽  
Caudal Peduncle ◽  
Anterior Process ◽  
Males And Females ◽  
A New Species

Pseudancistrus sidereus is described from two collections of specimens from Amazonas, Venezuela. Pseudancistrus sidereus differs from all other members of Pseudancistrus based on the presence of a unique keel on the caudal peduncle formed from the concave dorsal sections of the plates in the ventral series, light spots on the body (these may be yellow in life) centered on the body plates and the absence of the characteristics of the more derived members of Pseudancistrus such as hypertrophied odontodes along the snout in males and females and the loss of evertibility of the cheek plates. Pseudancistrus includes Lithoxancistrus and Guyanancistrus and is diagnosed by the following synapomorphies: no suture between pterotic-supracleithrum and hyomandibula, no contact of the hyomandibula with the prootic, straight, spoon-shaped anterior process of metapterygoid, nasal bone not much wider than laterosensory canal running through it, sphenotic not contacting posteriormost infraorbital externally, and a short ventral ridge on the pelvic basipterygium (lost in some species). Two species formerly assigned to Guyanancistrus are placed in different genera. Hypostomus guacharote is placed in Lasiancistrus and Chaetostomus trinitatis is placed in Ancistrus.Se describe Pseudancistrus sidereus, con base en dos colectas de espec menes del Amazonas venezolano. Pseudancistrus sidereus difiere de los otros miembros del g nero Pseudancistrus por la presencia de una quilla nica en el ped nculo caudal formada a partir de las secciones c ncavas dorsales de las placas de la serie ventral, puntos blancos en el cuerpo (probablemente amarillos en vida) centrados en las placas corporales y la ausencia de ciertas caracter sticas presentes en los miembros m s derivados de Pseudancistrus, como odontodos hiperatrofiados a lo largo del rostro en machos y hembras y la perdida de evertibilidad de las placas de la mejilla. Pseudancistrus incluye a Lithoxancistrus y Guyanancistrus y se diagnostica por las siguientes sinapomorf as: sutura entre el pter tico-supracleitro y la hiomand bula ausente, hiomand bula y pro tico sin contacto, proceso anterior del metapterigoides recto y en forma de cuchara, hueso nasal apenas m s amplio que el canal laterosensorial que corre a trav s del mismo, esfen tico sin contacto externo

scholarly journals A multivariate study of variation in two species of rock crab of the genus Leptograpsus

1974 ◽  
Vol 22 (3) ◽  
pp. 417 ◽  
Author(s):  
NA Campbell ◽  
RJ Mahon
Keyword(s):  
Carapace Length ◽  
Carapace Width ◽  
The Body ◽  
Canonical Variate ◽  
Multivariate Approach ◽  
Maximum Width ◽  
Multivariate Study ◽  
Rock Crab ◽  
Males And Females ◽  
Colour Form

A multivariate approach has been used to study morphological variation in the blue and orange-form species of rock crab of the genus Leptograpsus. Objective criteria for the identification of the two species are established, based on the following characters: width of the frontal region of the carapace; width of the posterior region of the carapace (rear width); length of the carapace along the midline; maximum width of the carapace; and the depth of the body. The first canonical variate, which differentiates between the two species, represents a contrast between the carapace width relative to the width of the front lip and the depth of the body; the blue-form species has a greater relative carapace width than has the orange form. The second canonical variate, which presents a contrast between the rear width and the carapace length, identifies males and females within each species; males have a greater relative carapace length than have females. All individuals, including 20 not used in the study, were correctly identified for colour form. The clear separation of the blue and orange forms achieved by canonical analysis supports the previously determined specific status of the two forms.

scholarly journals Study of Second and Fourth Digit Lengths and Their Ratios With Physical Attributes in Nepali Population

2018 ◽  
Vol 16 (2) ◽  
pp. 78-81
Author(s):  
Biswas Satyal ◽  
Abhishek Satyal
Keyword(s):  
Ring Finger ◽  
The Body ◽  
Behavioral Traits ◽  
Digit Ratios ◽  
Hand Deformities ◽  
Significant Difference ◽  
Physical Attributes ◽  
Physical Traits ◽  
Left And Right ◽  
Males And Females

Introduction: The ratio of the lengths of the index and the ring finger (2D:4D ratio) is generally different between men and women. A number of studies have shown a correlation between the 2D:4D digit ratio and various physical and behavioral traits. The aim of the present study is to investigate the association of the index (2nd) and ring (4th) digit ratios with some physical traits in Nepal population. Material & Method: 200 students (100 males and 100 females) between ages of 18 years and above were randomly selected with exclusion of those with hand deformities. The digit lengths were measured from the basal crease to the tips usingvernier calipers. The 2D:4D ratios were determined for each subject while height and weight were used to calculate the body mass index and data analyzed. The study was conducted between January 2018 to November 2018. Result: The result of the anthropometric study of the differences in index (2D) and ring (4D) and their ratios shows that there was a significant difference between the length of index finger (2D), ring finger (4D) and the ratios of right hand's 2D:4D in both males and females. There was appositive correlation between the second digit length and Height and weight in males and females both on right and left sides. The 2D:4D ratio for both left and right hand did not show any positive correlation with height, weight or BMI of an individual.

scholarly journals Effect of nutrition on the body temperature and relative organ weights of broilers

2015 ◽  
Vol 36 (6Supl2) ◽  
pp. 4575
Author(s):  
Julyana Machado da Silva Martins ◽  
Evandro De Abreu Fernandes ◽  
João Paulo Rodrigues Bueno ◽  
Carolina Magalhães Caires Carvalho ◽  
Fernanda Heloisa Litz ◽  
...  
Keyword(s):  
Small Intestine ◽  
Body Temperature ◽  
Energy Levels ◽  
Liver Weight ◽  
The Body ◽  
Body Temperatures ◽  
Average Surface ◽  
Randomized Design ◽  
Males And Females ◽  
Completely Randomized Design

<p>The objective of this study was to evaluate the effect of different nutritional plans on the body temperature and organ biometrics in male and female broilers, of two ages. Here, 1,700 birds were used (850 males and 850 females) in a completely randomized design composed of five treatments (- 3%, - 1.5%, reference, + 1.5% and + 3%), with 10 repetitions, totaling 50 experimental units; the reference treatment based on nutritional and energy levels indicated in previous studies was calculated from this. At 35 and 42 d, the temperatures of the wing, head, shin, back, and cloaca in males and females were measured separately, and the average surface and body temperature were calculated. At 42 d, relative weights of the gizzard, liver, heart, and small intestine were calculated. The temperatures of the wings, back, and cloaca, and consequently the average surface temperature and body temperatures, were not affected by nutritional plans. Effects of increasing the nutritional and energy levels were observed on liver weights, the gizzard, and the small intestine. We conclude that the nutritional plans did not affect body temperature. Males had higher body temperatures than females. Body temperature increased with increase in age, and the increase in the nutritional plans increased liver weight and reduced the gizzard weights.</p>

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