scholarly journals Does Oxygen Content Play a Role in Spontaneous Closure of Perimembranous Ventricular Septal Defects?

Children ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 881
Author(s):  
Pier Paolo Bassareo ◽  
Giuseppe Calcaterra ◽  
Martino Deidda ◽  
Andrea Raffaele Marras ◽  
Giuseppe Mercuro

(1) Background: the impact of a series of laboratory parameters (haemoglobin, haematocrit, foetal haemoglobin, peripheral oxygen saturation, iron, transferrin, ferritin, and albumin) on perimembranous ventricular septal defects spontaneous healing was tested. (2) Methods: one hundred and seven patients were enrolled in the study (57% males; mean age 2.1 ± 0.4 years) and were subsequently subdivided into two groups: self-healing (n = 36) and in need of intervention (n = 71). Self-healing subjects were defined on the basis of an absence of residual shunts at colorDoppler across the previous defect. (3) Results: no statistically significant differences were reported in the size of perimembranous ventricular septal defects between the two groups (p = ns). Conversely, prevalence of anaemia was significantly higher in those requiring intervention than in the self-healing group (p < 0.03), while haemoglobin, iron, ferritin, and albumin levels were lower (p < 0.001, p < 0.05, p < 0.02, p < 0.007, respectively). In multivariable linear regression analysis, only haemoglobin and albumin were found to be associated with spontaneous closure (p < 0.005 and p < 0.02, respectively). In multiple logistic regression analysis, haemoglobin independently increased the probability of self-healing of perimembranous ventricular septal defects (p = 0.03). All patients needing an interventional closure of perimembranous ventricular septal defects presented with haemoglobin <12.7 g/dL. (4) Conclusion: the self-resolution of perimembranous ventricular septal defects seems to rely on numerous factors, including oxygen content, which is likely to promote cell proliferation as well as tissue regeneration. Haemoglobin blood concentration seems to influence the natural history of perimembranous ventricular septal defects and improvement of anaemia by supplementation of iron intake might represent a simple and reliable method to promote self-healing.

2019 ◽  
Vol 13 (2) ◽  
Author(s):  
Arief Hidayatullah Khamainy ◽  
Dessy Novitasari Laras Asih

The research was carried out to find the influence of training material and methods of training toward workability. The study was conducted respectively from an employee of PD BPR Bantul Yogyakarta. The purpose of this research is expected to be useful for stakeholders in seeing CSR disclosure in the company in testing and analyzing its effect on the company's financial performance and with the presence of anti-corruption exposure, whether it will strengthen the impact of CSR disclosure on the company's financial performance. The study population in this study were all mining companies registered on the Indonesia Stock Exchange in 2016-2018 with a total of 63 companies. The research sample was taken using a random sampling technique that was calculated by the Slovin formula so that 54 samples were obtained for analysis. Linear Regression Analysis and Moderation Regression Analysis were chosen as the analysis technique used in this study. The results show that CSR disclosure does not affect the company's financial performance, and anti-corruption disclosure does not affect the relationship between the two.


2021 ◽  
Vol 11 (2) ◽  
pp. 700
Author(s):  
Irene A. Kanellopoulou ◽  
Ioannis A. Kartsonakis ◽  
Costas A. Charitidis

Cementitious structures have prevailed worldwide and are expected to exhibit further growth in the future. Nevertheless, cement cracking is an issue that needs to be addressed in order to enhance structure durability and sustainability especially when exposed to aggressive environments. The purpose of this work was to examine the impact of the Superabsorbent Polymers (SAPs) incorporation into cementitious composite materials (mortars) with respect to their structure (hybrid structure consisting of organic core—inorganic shell) and evaluate the microstructure and self-healing properties of the obtained mortars. The applied SAPs were tailored to maintain their functionality in the cementitious environment. Control and mortar/SAPs specimens with two different SAPs concentrations (1 and 2% bwoc) were molded and their mechanical properties were determined according to EN 196-1, while their microstructure and self-healing behavior were evaluated via microCT. Compressive strength, a key property for mortars, which often degrades with SAPs incorporation, in this work, practically remained intact for all specimens. This is coherent with the porosity reduction and the narrower range of pore size distribution for the mortar/SAPs specimens as determined via microCT. Moreover, the self-healing behavior of mortar-SAPs specimens was enhanced up to 60% compared to control specimens. Conclusively, the overall SAPs functionality in cementitious-based materials was optimized.


2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Basri Basri

The objective of the study was to evaluate the impact of stores existence toward sales turnover of stalls in Mataram city. Associative research design was adopted as the study guide. Purposive sampling techniques were used in which 100 copies of the research instrument were administered to stalls owner in Mataram city, out of which 100 copies of questionnaire were filled and returned. Test of validity and reliability, classical assumption test, and multiple linear regression analysis was used to analyse the data generated from respondents. The findings revealed that stores existence variable consisted of services, product diversification, price, and comfortable of consumer have significant influence on sales turnover of stalls at 0,05 level (2-tailed). The result of the research shows the variables negatively affecting sales turnover of stalls. Furthermore, price ranks the first follow by comfortable, product diversification, and services. This research will help the owner of stalls to understand and recognize the ranking of variables affecting sales turnover of stalls in Mataram city. Keywords:   Stores Existence, Stall, and Sales Turnover.


2022 ◽  
Vol 18 (1) ◽  
pp. 80-100
Author(s):  
Rahayu Mardikaningsih ◽  
Samsul Arifin

Human assets as one of the elements of manufacturing are the riding pressure of each organisation. They have a main function in understanding the organisation's goals. Companies ought to constantly inspire them to offer the excellent paintings effects in order that organisation sports aren't hampered consistent with their workload and responsibilities. Good paintings effects are primarily based totally at the lifestyles of a cause for fulfillment and there are numerous variables that have effect on this. This studies targets to research and decide the impact of labor supervision, paintings revel in, and paintings cappotential on fulfillment motivation. This quantitative studies takes the populace targeted on personnel who paintings withinside the manufacturing phase of a multinational organisation in Sidoarjo. Respondents on this observe have been a hundred and twenty respondents. The analytical device used, particularly SPSS model 25 program. The sampling method on this observe the usage of purposive sampling method. The analytical device used is more than one linear regression analysis. The effects confirmed that each one hypotheses have been demonstrated correct. Work supervision has a massive effective impact on fulfillment motivation. Work revel in and paintings cappotential even have a massive have effect on fulfillment motivation. The 3 of them offer a massive impact concurrently on fulfillment motivation. Keywords: job supervision, work experience, work ability, achievement motivation.


2021 ◽  
Author(s):  
Eva Trisnawati Chumairoh ◽  
Trianggoro Wiradinata

This purpose of this study was to determine the effect of leadership, motivation and discipline on employee performance. The independent variables were leadership (X1), motivation (X1) and discipline (X3). The dependent variable was employee performance (Y). This was explanatory research with a quantitative approach. The study was conducted at PT Surabaya Marine with employees. Data analysis was carried out through multiple linear regression analysis with the F test and t test. Employee performance was strongly influenced by leadership, motivation and discipline. Keywords: leadership, motivation, discipline, employee performance


Author(s):  
Ayuto Kodama ◽  
Yu Kume ◽  
Sangyoon Lee ◽  
Hyuma Makizako ◽  
Hiroyuki Shimada ◽  
...  

Background: Recent longitudinal studies have reported proportion of frailty transition in older individuals during the COVID-19 pandemic. Our study aimed at clarifying the impact of social frailty in community-dwelling older adults during the COVID-19 pandemic and at identifying factors that can predict transition to social frailty. Methods: We performed this study from 2019 (before declaration of the state of emergency over the rising number of COVID-19 cases) to 2020 (after declaration of the emergency). We applied Makizako’s social frail index to our study subjects at the baseline and classified into robust, social prefrailty, and social frailty groups. Multiple logistic regression analysis was performed using robust, social prefrailty, or social frailty status as dependent variable. Results: Analysis by the Kruskal–Wallis test revealed significant differences in the score on the GDS-15 among the robust, social prefrailty, and social frailty groups (p < 0.05). Furthermore, multiple regression analysis identified a significant association between the social frailty status and the score on GDS-15 (odds ratio, 1.57; 95% confidence interval (95% CI), 1.15–2.13; p = 0.001). Conclusion: The increase in the rate of transition of elderly individuals to the social frailty group could have been related to the implementation of the stay-at-home order as part of the countermeasures for COVID-19. Furthermore, the increased prevalence of depressive symptoms associated with the stay-at-home order could also have influenced the increase in the prevalence of social frailty during the COVID-19 pandemic.


2011 ◽  
Vol 66-68 ◽  
pp. 683-687 ◽  
Author(s):  
Li Zhang ◽  
Yan Jue Gong ◽  
Shuo Zhang

By designing the different formulations of the composites and adopting optimized technology including extrusion and molding, the effects of the Micro-capsules on the properties of nylon composites are analyzed by the impact property test. The mechanical impact property of the glass fiber reinforced nylon composites is influenced little if the content of the self-healing microcapsules added is less than 3.5%, and the technology of self-healing microcapsules used in the polymer composite gear is feasible.


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Seong-Joon Lee ◽  
Yang-Ha Hwang ◽  
Ji Man Hong ◽  
Jin Wook Choi ◽  
Dong-Hun Kang ◽  
...  

Introduction: Given the recent positive endovascular therapy trials for acute ischemic stroke (AIS), this therapeutic strategy is now being increasingly incorporated into routine clinical practice. Identifying prognostic factors among AIS patients receiving endovascular revascularization treatments (ERT) in the real world could be important for clinicians and patients. While the impact of diabetes mellitus (DM) on IV thrombolytic outcomes after AIS has been extensively investigated, there is a paucity of data assessing effects of DM on ERT outcomes after AIS. We evaluated the impact of comorbid DM on ERT for AIS. Methods: From Jan 2011 to Feb 2016, patients with AIS who underwent ERT for cervicocephalic occlusions were consecutively enrolled into the Acute Stroke due to Intracranial Atherosclerotic occlusion and Neurointervention - Korean Retrospective (ASIAN KR) registry from 3 hospitals. Patients were excluded if onset to puncture time over 8 hours, in-hospital stroke, or unavailable 3-month mRS. DM was diagnosed if a patient had the history, or hemoglobin A1c on admission was over 6.5. Univariate analysis was performed to compare the characteristics between DM and non-DM population. Multiple logistic regression analysis was used to validate the effect of comorbid DM on 3 month outcomes. Results: Of 721 patients, 667 (93%) were finally included, with 233 DM patients and 434 non-DM patients. In the univariate analysis, comorbidity with hypertension (71.2% vs. 58.3%, p=0.001) and dyslipidemia (36.7% vs. 26.7%, p=0.012) were more frequent in the DM population. Periprocedural factors such as target vessels, intravenous thrombolysis, and final reperfusion grades did not differ. Good outcomes with mRS 0-2 were less frequent in the DM population (43.3% vs. 53.7%, p=0.011). In the logistic regression analysis adjusting age, male sex, initial NIHSS, premorbid mRS, hypertension history, atrial fibrillation, intravenous thrombolysis, onset to puncture time and successful reperfusion, DM was an independent predictor of poor outcomes (mRS 3-6; 1.933, 1.274-2.933, p=0.002). Conclusion: In patients receiving ERT for AIS due to cervicocephalic artery occlusions, the presence of DM as a comorbidity confers greater odds of a poor functional outcome.


Author(s):  
Abdelmajid Ibenrissoul ◽  
Khawla Bouraqqadi ◽  
Souhaila Kammoun

The purpose of the chapter is to study what effect CSR has on firms' overall performance in a developing country context. While most of the previous empirical researches focused on the relationship between CSR and financial performance, the present study suggests exploring the impact of CSR on overall performance which encompasses economic, environmental, and social dimensions as well as stakeholders. The empirical study aims to analyze and measure the social and environmental involvement of large Moroccan firms operating in the main sectors of activity and located in different geographical areas. Using multiple linear regression analysis, the authors empirically test the impact of CSR on overall performance on a sample of 44 companies. The main findings reveal that CSR is a driver for improving image and reputation, enabling the firm to achieve overall corporate performance. On the basis of the main results, they set out some managerial implications and further directions for CSR research in developing countries.


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