scholarly journals Fabrication of Poly(pentaerythritol tetrakis (3-mercaptopropionate)/dipentaerythritol penta-/hexa-acrylate)HIPEs Macroporous Scaffold with Alpha Hydroxyapatite via Photopolymerization for Fibroblast Regeneration

Crystals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 746
Author(s):  
Muhammad Imran Azman ◽  
Nunthawan Kwangsawart ◽  
Jitima Preechawong ◽  
Manit Nithitanakul ◽  
Pornsri Sapsrithong
Keyword(s):  
Maximum Stress ◽  
Cell Attachment ◽  
Promising Result ◽  
Low Cost ◽  
Vital Role ◽  
Compressive Modulus ◽  
Polymerization Reaction ◽  
Porous Scaffolds ◽  
Support Cell ◽  
Biomaterial Application

Synthetic biomaterials that can be structured into porous scaffolds for support cell growth have played a role in developing the field of tissue engineering. This research focused on combination of biodegradable emulsion template along with the assisting of low-cost polymerization reaction. The appendage of ester-based surfactant, Hypermer B246, played a vital role which gave an outstanding dispersion in HIPEs system and degradability. PolyHIPEs were prepared by using domestic ultraviolet light source for producing a multiscale porosity material. The morphology showed a promising result of poly(pentaerythritol tetrakis (3-mercaptopropionate)/dipentaerythritol penta-/hexa-acrylate)HIPEs with varied Hypermer B246 surfactant concentration resulting in the pores size increased in between 51.2 ± 9.8 µm to 131.4 ± 26.32 µm. Cellular moieties of poly(TT/DPEHA) HIPEs were confirmed by using SEM while inclusion of hydroxyapatite were confirmed by SEM, FTIR and EDX-SEM and quantified by thermogravimetric analysis. The maximum stress and compressive modulus of the obtained materials were significantly enhanced with HA up to five percent by weight. Poly(TT/DPEHA)HIPEs with HA showed the ability for the cell attachment and the adhesion/proliferation of the cells, suggested that poly(TT/DPEHA) HIPEs with HA were suitable for biomaterial application.

scholarly journals Improvement on small-scale tuna fisheries data quality through the application of e-logbook system

2021 ◽  
Vol 869 (1) ◽  
pp. 012020
Author(s):  
S A Raup ◽  
S Patmiarsih ◽  
R D Juniar ◽  
B Setyadji
Keyword(s):  
Data Quality ◽  
Promising Result ◽  
Low Cost ◽  
Vital Role ◽  
Dependent Data ◽  
Small Scale ◽  
Insufficient Data ◽  
General Data ◽  
Tuna Fisheries ◽  
Temporal Coverage

Abstract Tuna and tuna-like fisheries play a vital role in Indonesian livelihood, especially in the archipelagic waters. However, despite the importance, the concern in general data collection activities for tuna, i.e., limited, with incomplete scientific knowledge and insufficient data has hampered the assessment. The purpose of this study was to analyse on how fisheries-dependent data system could transform the data quality. E-logbook has the best attribute for reaching the goals, especially for small-scale tuna fisheries. Characterised by low cost and vast spatial and temporal coverage, it is convinced on why the program should be expanded and monitored carefully. Analysis on fisheries indicators showed a promising result, especially for filling the gap which could not be covered by research.

Glycans in scaffold design in tissue reconstruction

2021 ◽  
pp. 088391152199784
Author(s):  
Nipun Jain ◽  
Shashi Singh
Keyword(s):  
Cell Attachment ◽  
Low Cost ◽  
Growth Conditions ◽  
Downstream Signaling ◽  
Cell Carrier ◽  
Wide Range ◽  
Proliferation And Differentiation ◽  
Different Types ◽  
Tissue Reconstruction ◽  
A Cell

Development of an artificial tissue by tissue engineering is witnessed to be one of the long lasting clarified solutions for the damaged tissue function restoration. To accomplish this, a scaffold is designed as a cell carrier in which the extracellular matrix (ECM) performs a prominent task of controlling the inoculated cell’s destiny. ECM composition, topography and mechanical properties lead to different types of interactions between cells and ECM components that trigger an assortment of cellular reactions via diverse sensing mechanisms and downstream signaling pathways. The polysaccharides in the form of proteoglycans and glycoproteins yield better outcomes when included in the designed matrices. Glycosaminoglycan (GAG) chains present on proteoglycans show a wide range of operations such as sequestering of critical effector morphogens which encourage proficient nutrient contribution toward the growing stem cells for their development and endurance. In this review we discuss how the glycosylation aspects are of considerable importance in everyday housekeeping functions of a cell especially when placed in a controlled environment under ideal growth conditions. Hydrogels made from these GAG chains have been used extensively as a resorbable material that mimics the natural ECM functions for an efficient control over cell attachment, permeability, viability, proliferation, and differentiation processes. Also the incorporation of non-mammalian polysaccharides can elicit specific receptor responses which authorize the creation of numerous vigorous frameworks while prolonging the low cost and immunogenicity of the substance.

scholarly journals Synthesis of poly (n-butyl acrylate) with tempo by nitroxide mediated polymerization method

2021 ◽  
pp. 096739112110245
Author(s):  
Amrita Sharma ◽  
PP Pande
Keyword(s):  
Butyl Acrylate ◽  
Low Cost ◽  
Polymerization Process ◽  
Polymerization Reaction ◽  
High Concentration ◽  
Acrylate Monomer ◽  
Controlled Polymerization ◽  
Acrylate Monomers ◽  
Nitroxide Mediated Polymerization ◽  
Polymerization Method

It has been observed that acrylate monomers are very difficult to polymerize with the low cost nitroxide catalyst 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO). Therefore, costly acyclic nitroxides such as N-tert-butyl-N-(1-diethylphosphono-2,2-dimethyl)-N-oxyl, (SG1), 2,2,5-Trimethyl-4-phenyl-3-azahexane-3-nitroxide (TIPNO) and TIPNO derivatives have to be used for the polymerization of the acrylic acid derivatives. There are very few reports on the use of TEMPO-derivatives toward the polymerization of n-butyl acrylate. Generally different reducing agents viz. glucose, ascorbic acid, hydroxyacetone etc. have been used to destroy excess TEMPO during the polymerization reaction. The acrylate polymerizations fail in the presence of TEMPO due to the strong C–O bond formed between the acrylate chain end and nitroxide. To the best of our knowledge, no literature report is available on the use of TEMPO without reducing agent or high temperature initiators, toward the polymerization of n-butyl acrylate. The present study has been carried out with a view to re-examine the application of low cost nitroxide TEMPO, so that it can be utilized towards the polymerization of acrylate monomers (e.g. n-butyl acrylate). We have been able to polymerize n-butyl acrylate using the nitroxide TEMPO as initiator (via a macroinitiator). In this synthesis, a polystyrene macroinitiator was synthesized in the first step from TEMPO, after this TEMPO end-capped styrene macroinitiator (PSt-TEMPO) is used to polymerize n-butyl acrylate monomer. The amount of macroinitiator taken was varied from 0.05% to 50% by weight of n-butyl acrylate monomer. The polymerization was carried out at 120°C by bulk polymerization method. The experimental findings showed a gradual increase in molecular weight of the polymer formed and decrease in the polydispersity index (PDI) with increase in amount of PSt-TEMPO macroinitiator taken. In all experiments conversion was more than 80%. These results indicate that the polymerization takes place through controlled polymerization process. Effect of different solvents on polymerization has also been investigated. In the following experiments TEMPO capped styrene has been used as macroinitiator leading to the successful synthesis of poly n-Butyl acrylate. It has been found that styrene macroinitiator is highly efficient for the nitroxide mediated polymerization, even in very small concentration for the synthesis of poly n-butyl acrylate. High concentration of macroinitiator results in the formation of block copolymers of polystyrene and poly ( n-butyl acrylate) viz. polystyrene-block-poly-( n-butyl acrylate). The use of TEMPO toward controlled polymerization is of much importance, because it is the nitroxide commercially available at the lowest cost.

scholarly journals Redox initiation in semicontinuous polymerization to search for specific mechanical properties of copolymers

e-Polymers ◽  
2020 ◽  
Vol 20 (1) ◽  
pp. 613-623
Author(s):  
José Manuel Sandoval-Díaz ◽  
Francisco Javier Rivera-Gálvez ◽  
Marta Fernández-García ◽  
Carlos Federico Jasso-Gastinel
Keyword(s):  
Low Cost ◽  
Mechanical Analysis ◽  
Industrial Applications ◽  
Size Exclusion ◽  
Proton Nuclear Magnetic Resonance ◽  
Polymerization Reaction ◽  
Redox Initiation ◽  
Initiation System ◽  
Feeding Profile ◽  
Chain Composition

AbstractIn this work, for a semicontinuous emulsion polymerization reaction, it is shown that using a redox initiation system at 40°C, substantial modifications in copolymer chain composition with conversion can be easily obtained. To test controllable trajectories for comonomer feeding, linear and parabolic profiles were chosen to get different types of chain composition variations for the 50/50 w/w styrene/n-butyl acrylate system. For the “forced composition copolymers,” the molecular weight averages and distribution were obtained by size exclusion chromatography. The composition along conversion was followed by proton nuclear magnetic resonance to determine the weight composition distribution (WCD) of the copolymer chains. Mechanodynamic (dynamic-mechanical analysis), tensile, and hardness tests exhibited consistent results depending on the WCD that outcomes from the respective feeding profile. The results confirm that this methodology is of great potential for industrial applications when looking for synergy in copolymer properties, and low-cost processes.

Developing low-cost methane gas concentration measuring device

2021 ◽  
pp. 54-59
Author(s):  
Md. Mahidy Hossain ◽  
Nadim Khandaker
Keyword(s):  
Promising Result ◽  
Low Cost ◽  
Measurement Techniques ◽  
Health And Safety ◽  
Modern Science ◽  
Methane Content ◽  
Measuring Device ◽  
Methane Generation ◽  
Methane Gas ◽  
Wide Range

In every aspect of Engineering more advanced, efficient and progressive solutions are required. The modern age of science requires innovative minds. The field of environmental engineering is also advancing with modern science and technology innovations. Measuring of methane concentration and flow rate is nothing new, yet a complicated process. The need for more accurate measurement is a necessity in proper operation of bio digesters for methane generation. The traditional process of the measuring methane content in biogas is time consuming yet complicated. The need for development and application of methane measurement techniques is not only limited to biogas but has other monitoring value as well in other health and safety applications in built environments. Winsen Electronics and Hanwei Electronics are two of the leading sensor-manufactures of China who are providing a wide range of gas detecting sensors that are locally available in Bangladesh and yet has not been applied to methane content measurement in biogas operations. In This paper we are reporting on the application of a purpose-built propane, butane detector for methane gas detection within the range of accuracy for it to be applied in methane detection in a biogas stream. This paper, reports on application and calibration of the methane detecting sensor MQ-4 with promising result. Based on the study we postulate that the sensor can be used to detect methane for an on-line monitoring of many environmental, industrial purposes such as bio digesters, integrated waste management facility. The cost of fabrication of the sensor system is only $18 making it a viable sensor with respect to cost for application in Bangladesh.

Photocatalytic Degradation of Synthetic Sulfur Pollutants in Petroleum Fractions under Different pH and Photocatalyst

2021 ◽  
Vol 02 (01) ◽  
Author(s):  
Mohamad Alif Hakimi Hamdan ◽  
◽  
Nur Hanis Hayati Hairom ◽  
Nurhafisza Zaiton ◽  
Zawati Harun ◽  
...  
Keyword(s):  
Photocatalytic Degradation ◽  
Zno Nanoparticles ◽  
Low Cost ◽  
Industrial Effluents ◽  
Degradation Process ◽  
Vital Role ◽  
Petroleum Fraction ◽  
Precipitation Method ◽  
Synthesis Process ◽  
Petroleum Fractions

Thiophene is one of the sulfur compounds in the petroleum fraction that can be harmful to living things and lead to a critical effect on the ecosystem. Photocatalytic degradation is one of the promising methods in treating wastewater as it can mineralization of pollutants into carbon dioxide and water. Other than that, this method is non-toxic and relatively low cost. The production of hydroxyl radicals playing a vital role in the degradation of organic pollutants. It has been claimed that the usage of zinc oxide (ZnO) nanoparticles could give an excellent degradation process as this photocatalyst have high photosensitivity, low cost and chemically stable. However, the preparation method of ZnO nanoparticles will affect the agglomeration, particle size, shape and morphology of particles and lead to influence the photocatalytic activity in degrading thiophene. Therefore, this study focused on the effectiveness of ZnO nanoparticles in the presence of fibrous nanosilica (KCC-1) and polyethylene glycol (PEG) as the capping agent to degrade synthetic thiophene. ZnO/KCC-1 had been synthesized via the precipitation method and characterized by using Fourier Transform Infrared (FTIR). The chemical bond and nature of the photocatalyst from the FTIR results proved that the synthesis process to produce the ZnO/KCC-1 was succeed. The large surface area of KCC-1 increases the effectiveness of ZnO which is supported by the experimental data. Accordingly, the optimum condition for photocatalytic degradation of thiophene is under pH 7 by using ZnO/KCC-1 as photocatalyst. Hence, it is believed that this research could be implemented to remove the thiophene in petroleum fraction from the actual industrial effluents and this can preserve nature in the future.

APPLICATION OF DENDRIMER/PLASMID hBMP-2 COMPLEXES LOADED INTO β-TCP/COLLAGEN SCAFFOLD IN THE TREATMENT OF FEMORAL DEFECTS IN RATS

2014 ◽  
Vol 26 (01) ◽  
pp. 1450005 ◽  
Author(s):  
Tingwei Bao ◽  
Huiming Wang ◽  
Wentao Zhang ◽  
Xuefeng Xia ◽  
Jiabei Zhou ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Type I Collagen ◽  
Cell Attachment ◽  
Collagen Scaffold ◽  
Bone Defects ◽  
Bone Morphogenetic Protein 2 ◽  
Porous Scaffolds ◽  
Type I

Purpose: Plasmid loading into scaffolds to enhance sustained release of growth factors is an important focus of regenerative medicine. The aim of this study was to build gene-activated matrices (GAMs) and examine the bone augmentation properties. Methods: Generation 5 polyamidoamine dendrimers (G5 dPAMAM)/plasmid recombinant human bone morphogenetic protein-2 (rhBMP-2) complexes were immobilized into beta-tricalcium phosphate (β-TCP)/type I collagen porous scaffolds. After cultured with rat mesenchymal stem cells (rMSCs), transfection efficiencies were examined. The secretion of rhBMP-2 and alkaline phosphatase (ALP) were detected to evaluate the osteogenic properties. Scanning electron microscopy (SEM) was used to observe attachment and proliferation. Moreover, we applied these GAMs directly into freshly created segmental bone defects in rat femurs, and their osteogenic efficiencies were evaluated. Results: Released plasmid complexes were transfected into stem cells and were expressed, which caused osteogenic differentiations of rat mesenchymal stem cells (rMSCs). SEM analysis showed excellent cell attachment. Bioactivity of plasmid rhBMP-2 was maintained in vivo, and the X-ray observation, histological analysis and immunohistochemistry (IHC) of bone tissue demonstrated that the bone healing in segmental femoral defects was enhanced by implantation of GAMs. Conclusions: Such biomaterials offer therapeutic opportunities in critical-sized bone defects.

scholarly journals Nutritive Analysis of Cicer Arietinum Via Colorimetery

2019 ◽  
Vol 9 (2S2) ◽  
pp. 249-252
Keyword(s):  
Cicer Arietinum ◽  
Low Cost ◽  
Vital Role ◽  
Value Addition

The seeds of cicerarietinum were made into flour, cooked in a different methods and analyzed for Phosphorous, Phytin, Ionisable Iron, Niacin and Thiamin by standard methods.Nutritious values of cicerarietinum varies significantly when they cooked. Mode of cooking play a vital role in the determination of nutrition in food. Gram flour has significant amounts of niacin and thiamin and ionisable iron in its uncooked flour form.This flour have 280 mg/100g phosphorous, 1.6 mg/100g ionisable iron, 0.357 mg/100g thiamin and 4.7 mg/100g niacin. Thus, the flour may be used as value addition food which in turn increased nutrition in low cost.

scholarly journals A Concept Design of an Adaptive Tendon Driven Mechanism for Active Soft Hand Orthosis

Proceedings ◽  
2020 ◽  
Vol 64 (1) ◽  
pp. 21
Author(s):  
Bruno Lourenço ◽  
Vitorino Neto ◽  
Rafhael de Andrade
Keyword(s):  
Degrees Of Freedom ◽  
Low Cost ◽  
Vital Role ◽  
Dorsal Side ◽  
Concept Design ◽  
Cord Injury ◽  
3D Printed ◽  
Biomechanical Constraints ◽  
Active Orthosis

The Hands exert a vital role in the simplest to most complex daily tasks. Losing the ability to make hand movements, which is usually caused by spinal cord injury or stroke, dramatically impacts the quality of life. In order to counteract this problem, several assisting devices have been proposed, but they still present several usage limitations. The marketable orthoses are generally either the static type or over-expensive active orthosis that cannot perform the same degrees of freedom (DoF) that a hand can do. This paper presents a conceptual design of a tendon-driven mechanism for hand’s active orthosis. This study is a part of an effort to develop an effective and low-cost hand’s orthosis for people with hand paralysis. The tendon design proposed was thought to comply with some requisitions such as lightness and low volume, as well as fit with the biomechanical constraints of the hand joints to enable a comfortable use. The mechanism employs small cursors on the phalanges to allow the tendons to run on the dorsal side and by both sides of the fingers, allowing 2 DoF for each finger, and one extra tendon enlarges the hands’ adduction nuances. With this configuration, it is simple enough to execute the flexion and extension movements, which are the most used movements in daily actives, using one single DC actuator for one DoF to reduce manufacturing costs, or with more DC actuators to enable more natural hand coordination. This system of actuation is suitable to create soft exoskeletons for hands easily embedded into 3D printed parts, which could be merged over statics thermoplastic orthosis. The final orthosis design allows dexterous finger movements and force to grasp objects and perform tasks comfortably.

scholarly journals High Security Mechanism: Fragmentation and Replication in the Cloud with Auto Update in the System.

2020 ◽  
Vol 5 (2) ◽  
pp. 54-59
Author(s):  
Shrutika Khobragade ◽  
Rohini Bhosale ◽  
Rahul Jiwahe
Keyword(s):  
Cloud Computing ◽  
Low Cost ◽  
Vital Role ◽  
Third Party ◽  
Key Generation ◽  
Huge Amount ◽  
Security Issues ◽  
Hash Key ◽  
Use Of Internet ◽  
High Quality Service

Cloud Computing makes immense use of internet to store a huge amount of data. Cloud computing provides high quality service with low cost and scalability with less requirement of hardware and software management. Security plays a vital role in cloud as data is handled by third party hence security is the biggest concern to matter. This proposed mechanism focuses on the security issues on the cloud. As the file is stored at a particular location which might get affected due to attack and will lost the data. So, in this proposed work instead of storing a complete file at a particular location, the file is divided into fragments and each fragment is stored at various locations. Fragments are more secured by providing the hash key to each fragment. This mechanism will not reveal all the information regarding a particular file even after successful attack. Here, the replication of fragments is also generated with strong authentication process using key generation. The auto update of a fragment or any file is also done here. The concept of auto update of filles is done where a file or a fragment can be updated online. Instead of downloading the whole file, a fragment can be downloaded to update. More time is saved using this methodology.

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