Body Fat Parameters, Glucose and Lipid Profiles, and Thyroid Hormone Levels in Schizophrenia Patients with or without Metabolic Syndrome

In this study, we aim to investigate associations between body fat parameters, glucose and lipid profiles, thyroid-stimulating hormone (TSH), and thyroid hormones (THs) levels in Tomsk-region schizophrenia patients depending upon the presence or absence of metabolic syndrome (MetS). A total of 156 psychiatric inpatients with schizophrenia who had been treated with antipsychotics for at least six months before entry were studied: 56 with and 100 without MetS. Reference groups consisted of general hospital inpatients with MetS and without schizophrenia (n = 35) and healthy individuals (n = 35). Statistical analyses were performed using the Mann–Whitney U-test, chi-square test, Spearman’s rank correlation coefficient, multiple regression analyses, and descriptive statistics. Patients with schizophrenia and MetS had significantly higher levels of free triiodothyronine (FT3) and thyroxine (FT4) compared to schizophrenia patients without MetS (3.68 [3.25; 5.50] vs. 3.24 [2.81; 3.66], p = 0.0001, and 12.68 [10.73; 15.54] vs. 10.81 [9.76; 12.3], p = 0.0001, in pmol/L, respectively). FT3 maintained an association with MetS (p = 0.0001), sex (p = 0.0001), age (p = 0.022), and high-density lipoproteins (p = 0.033). FT4 maintained an association with MetS (p = 0.0001), sex (p = 0.001), age (p = 0.014), and glucose (p = 0.009). The data obtained showed body fat parameters, glucose and lipid profiles, and THs levels in Western-Siberian schizophrenia patients depending on MetS presence or absence.

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Dentists’ knowledge of fluoride cariostatic mechanisms

Nowa Stomatologia ◽

10.25121/ns.2018.23.3.102 ◽

2018 ◽

Vol 23 (3) ◽

Author(s):

Urszula Kaczmarek ◽

Wojciech Kowalczyk ◽

Dariusz Gozdowski ◽

Dorota Olczak-Kowalczyk

Keyword(s):

Rank Correlation ◽

Bone Fragility ◽

Caries Prevention ◽

Water Fluoridation ◽

Chi Square ◽

Significance Level ◽

Spearman’S Rank Correlation ◽

Spearman’S Rank Correlation Coefficient ◽

Chi Square Test ◽

Almost All

Introduction. The use of age- and risk-adjusted caries prevention requires up-to-date knowledge on the cariostatic effects of fluoride, as well as the methods and safety of fluoride prophylaxis. Aim. The aim of the study was to assess dentists’ knowledge of the safety and mechanism of anticaries effects of fluoride. Material and methods. An anonymous questionnaire was conducted among 212 dentists participating in dental training. The questions included in the questionnaire related to knowledge about water fluoridation, fluoride cariostatic mechanisms and the safety of fluoride prophylaxis. The chi-square test and the Spearman’s rank correlation coefficient were used for statistical analysis. A significance level of 0.05 was used. Results. Incorrect knowledge about water fluoridation was demonstrated by 26.9% of respondents in the country and 16.0% of respondents in Europe. Most respondents (80.7%) reported higher efficacy of exogenous vs endogenous anticaries approaches, and more than half of respondents (59.0%) considered the processes of remineralisation and demineralisation as the most important anticaries activity. Almost all respondents (95.7%) agreed that the use of fluoride for caries prevention is controversial, mainly due to its dose-dependent therapeutic or toxic effects (85.4%). According to about 20% of respondents, cariostatic fluoride doses have adverse effects on the general health, mainly in the form of bone fragility (10.4%). Conclusions. Lack of correct knowledge about the dominant cariostatic effects of fluoride may result in the choice of an inappropriate preventive method or avoiding local application of fluoride preparations for fear of adverse systemic effects, which may in turn lead to increased caries prevalence in a given population.

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An Analysis of the Condition of the Tourist Brand and Tourist Attractiveness of the Podkarpackie Region Based on the Brand Asset Valuator Model

Polish Journal of Sport and Tourism ◽

10.2478/pjst-2019-0012 ◽

2019 ◽

Vol 26 (2) ◽

pp. 34-39

Author(s):

Beata Gierczak-Korzeniowska

Keyword(s):

Applied Research ◽

Rank Correlation ◽

Point Of View ◽

Chi Square ◽

Spearman’S Rank Correlation ◽

Spearman’S Rank Correlation Coefficient ◽

Ecological Aspects ◽

Historical Heritage ◽

Term Management

AbstractIntroduction. There are many factors which determine the attractiveness of a region for tourists. However, such assessments are, relatively rarely, a result of the analysis of the presence and condition of regional tourist brands and their perception among visitors. The analysis and assessment of the condition of a brand can be carried out using the BAV (Brand Asset Valuator). This is an extremely interesting and useful tool which explains the dynamics of behaviour of brands on the market and diagnoses their “health”, supporting the process of their long-term management.Materials and methods. On the basis of the results of a pilot study, an attempt is made to measure the tourist attractiveness of the Podkarpackie region through the assessment of regional tourist brands and their features which are important from the point of view of the inhabitants of the region. The BAV model was used to analyse 32 tourist products. The applied research methods include the Mann-Whitney test, Spearman’s rank correlation coefficient, and the chi-square independence test.Results. The mapped data analysis based on the BAV model showed that 16 out of 32 products assessed were located in the leadership quadrant. The majority of the remaining products were in the development or decline phases.Conclusions. The presence of branded tourist products and their number have an impact on the tourist attractiveness of the region. The following aspects of the region were considered the most attractive: nature (natural surroundings, natural values, and ecological aspects), heritage (historical heritage and monuments and presentation of important past events), and tourism (tourism and recreation offerings).

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How well does the capillary thyroid-stimulating hormone test for newborn thyroid screening predict the venous free thyroxine level?

Archives of Disease in Childhood ◽

10.1136/archdischild-2015-309529 ◽

2016 ◽

Vol 101 (6) ◽

pp. 539-545 ◽

Cited By ~ 5

Author(s):

Tzveta Pokrovska ◽

Jeremy Jones ◽

M Guftar Shaikh ◽

Sarah Smith ◽

Malcolm D C Donaldson

Keyword(s):

Newborn Infants ◽

Rank Correlation ◽

Thyroid Stimulating Hormone ◽

Free Thyroxine ◽

Thyroid Function Tests ◽

Spearman’S Rank Correlation ◽

Thyroid Screening ◽

Spearman’S Rank Correlation Coefficient ◽

Venous Sample ◽

Stimulating Hormone

ObjectivesTo determine, in newborn infants referred with elevated capillary thyroid-stimulating hormone (TSH), a threshold below which a frankly subnormal venous free thyroxine (fT4) level of <10 pmol/L is unlikely, so that treatment with levo-thyroxine (L-T4) might be deferred until venous thyroid function tests (TFTs) become available.Subjects and methodsAll infants referred in Scotland since 1979 with capillary TSH elevation were studied, with particular focus on infants screened using the AutoDELFIA assay between 2002 and 2013.ResultsOf the 321 infants referred with capillary TSH elevation using AutoDELFIA, 35 were excluded (fT4/TSH unavailable (12), venous sample either preceding or >10 days after capillary sampling (13, 10)), leaving 286 eligible for analysis (208 definite/probable hypothyroidism, 61 transient TSH elevation, 17 of uncertain thyroid status). Capillary TSH and venous T4 were strongly correlated (Spearman's rank correlation coefficient −0.707355). The optimal capillary TSH threshold for predicting a venous fT4 of <10 pmol/L was found to be >40 mU/L (90.3% sensitivity and 65.9% specificity compared with 90.25% and 59.1% for >35 mU/L and 88.3% and 68.2% for >45 mU/L). 93 infants (32.5%) had capillary TSH ≤40 mU/L at referral of whom 15 (9.7%) had venous fT4 <10 pmol/L, comprising seven with true congenital hypothyroidism, five with transient TSH elevation and three with uncertain status, two of whom died.ConclusionFor infants in whom capillary TSH is ≤40 mU/L, it is reasonable to defer L-T4 treatment until venous TFT results are known provided that the latter become available quickly.

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Does Metabolic Syndrome Determine Severity and Disability of Chronic Low Backache?

Journal of Neurosciences in Rural Practice ◽

10.4103/jnrp.jnrp_430_17 ◽

2018 ◽

Vol 09 (02) ◽

pp. 208-213 ◽

Cited By ~ 1

Author(s):

Jayantee Kalita ◽

Kamlesh Kumar Sonkar ◽

Usha Kant Misra ◽

Sanjeev K. Bhoi

Keyword(s):

Metabolic Syndrome ◽

National Cholesterol Education Program ◽

Rating Scale ◽

Rank Correlation ◽

Numeric Rating Scale ◽

Test Results ◽

Adult Treatment Panel ◽

Chi Square ◽

Spearman’S Rank Correlation ◽

Numeric Rating

ABSTRACT Introduction: Obesity may be associated with more severe and disabling low backache (LBA) due to alteration in biomechanics, but there are no such studies from developing countries. Aims: We report the frequency of metabolic syndrome (MS) in chronic LBA (CLBA) and its association with severity and disability of CLBA. Subjects and Methods: Consecutive patients with CLBA attending to the neurology service from October 2015 to February 2016 were included in the study. Clinical and demographic parameters were recorded. Routine biochemical test was done. The severity of pain was assessed by a 0–10 Numeric Rating Scale (NRS) and disability by Oswestry Disability Index (ODI) version 2. Comparison of variables was done by Chi-square or independent t-test and correlation by Karl Pearson or Spearman's rank correlation test. Results: Seventy-none (39.3%) patients had MS as per the International Diabetic Federation (IDF) criteria and 68 (33.8%) as per the National Cholesterol Education Program Adult Treatment Panel III criteria. Abdominal obesity was the most common (171 [85.1%]) feature of MS. The patients with MS had longer duration of sitting work and did less frequently exercise. The NRS score (6.95 ± 1.06 vs. 6.65 ± 0.95; P = 0.04) and ODI score (54.91 ± 8.42 vs. 51.89 ± 8.54; P = 0.01) were higher in CLBA patients with MS compared to those without MS. Conclusion: About 40% patients with CLBA have metabolic syndrome, and they have more severe pain and disability.

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Strategy, Corporate Culture, Structure and Operational Processes as the Context for the Innovativeness of an Organization

Foundations of Management ◽

10.2478/fman-2018-0004 ◽

2018 ◽

Vol 10 (1) ◽

pp. 33-44 ◽

Cited By ~ 2

Author(s):

Katarzyna Szczepańska-Woszczyna

Keyword(s):

Corporate Culture ◽

New Products ◽

Rank Correlation ◽

Chi Square ◽

Spearman’S Rank Correlation ◽

Spearman’S Rank Correlation Coefficient ◽

Two Measures ◽

Operational Processes ◽

The Relationship ◽

Weak Influence

Abstract The paper refers to relationships between the innovativeness of an organization and its selected determinants such as strategy, corporate culture, structure and operational processes. Research was conducted among 200 managers at the top, middle and operational levels of management (200 companies operating in Poland implementing innovations - innovative companies). Conditions leading to innovations are described as the combination of processes, which result from the internal and external dynamics of a given entity. The analysis assumed that the assessment of company innovativeness would be based on an assessment of whether the company is a leader in the industry in terms of new products (the higher the rating, the more innovative the company is considered to be). The relationship between the dimensions of the company's functioning and the degree of its innovativeness was rated on the basis of two measures: the Spearman's rank correlation coefficient and the chi-square coefficient. It was assumed that the most innovative companies have structures similar to organic ones, with a weak influence of the elements of mechanistic structures. This assumption was proven in relation to features of organizations considered important for innovativeness.

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The loyalty on the market of agricultural machines

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis ◽

10.11118/actaun201159020275 ◽

2011 ◽

Vol 59 (2) ◽

pp. 275-278

Author(s):

Zuzana Schwarzová ◽

Šárka Stojarová

Keyword(s):

Correlation Coefficient ◽

Marketing Research ◽

Rank Correlation ◽

Agricultural Machinery ◽

Chi Square ◽

Spearman’S Rank Correlation ◽

Spearman’S Rank Correlation Coefficient ◽

Brand Marks ◽

Chi Square Test ◽

And Behavior

The article is dealing with the market of agricultural machinery with the focus on the loyalty of agricultural subjects. In this market the brand is very important factor that can influence fundamentally the purchaser during buying a machine. Totally there are three types, the subjects that are totally not influenced by the brand mark, the subjects taking in their consideration the brand mark but just as one factor and the rest that is loyalty and buys just one brand. The main objective of this paper is to analyze the customers in this market and their loyalty to each brand. To reach the main goal there were analyzed data of agricultural subject’s facilities, perception of brand marks and their relation. The data were used from own primary marketing research and analyzed by the help of statistics methods for marketing research as a Chi-square test, Pearson product-moment correlation coefficient, Spearman’s rank correlation coefficient and testing the hypotheses. The other part of this paper was focused on the satisfaction of respondents with each brand that they own. According to the article objective there were set hypotheses for following testing that were main mean to solve the goal. The result of this paper is found loyalty for just one brand in the agricultural machinery market. For John Deere brand there was proven the loyalty – subjects perceiving the mark as the best in the market and also buying it. The results can help for our future analyses to understand factors influencing the market and analyses of each brand and how their strategy in the market is conformed to the subject perception and behavior.

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Deregulation of lncRNA HIST1H2AG-6 and AIM1-3 in peripheral blood mononuclear cells is associated with newly diagnosed type 2 diabetes

BMC Medical Genomics ◽

10.1186/s12920-021-00994-z ◽

2021 ◽

Vol 14 (1) ◽

Author(s):

Hui Jiang ◽

Peian Lou ◽

Xiaoluo Chen ◽

Chenguang Wu ◽

Shihe Shao

Keyword(s):

Roc Curve ◽

Multivariate Logistic Regression Analysis ◽

Rank Correlation ◽

Differentially Expressed ◽

Healthy Controls ◽

Biological Functions ◽

Multivariate Logistic Regression ◽

Spearman’S Rank Correlation ◽

Spearman’S Rank Correlation Coefficient

Abstract Background Type 2 diabetes mellitus (T2DM) is mainly affected by genetic and environmental factors; however, the correlation of long noncoding RNAs (lncRNAs) with T2DM remains largely unknown. Methods Microarray analysis was performed to identify the differentially expressed lncRNAs and messenger RNAs (mRNAs) in patients with T2DM and healthy controls, and the expression of two candidate lncRNAs (lnc-HIST1H2AG-6 and lnc-AIM1-3) were further validated using quantitative real-time polymerase chain reaction (qRT-PCR). Spearman’s rank correlation coefficient was used to measure the degree of association between the two candidate lncRNAs and differentially expressed mRNAs. Furthermore, the KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway and GO (Gene Ontology) enrichment analysis were used to reveal the biological functions of the two candidate lncRNAs. Additionally, multivariate logistic regression analysis and receiver operating characteristic (ROC) curve analysis were performed. Results The microarray analysis revealed that there were 55 lncRNAs and 36 mRNAs differentially expressed in patients with T2DM compared with healthy controls. Notably, lnc-HIST1H2AG-6 was significantly upregulated and lnc-AIM1-3 was significantly downregulated in patients with T2DM, which was validated in a large-scale qRT-PCR examination (90 controls and 100 patients with T2DM). Spearman’s rank correlation coefficient revealed that both lncRNAs were correlated with 36 differentially expressed mRNAs. Furthermore, functional enrichment (KEGG and GO) analysis demonstrated that the two lncRNA-related mRNAs might be involved in multiple biological functions, including cell programmed death, negative regulation of insulin receptor signal, and starch and sucrose metabolism. Multivariate logistic regression analysis revealed that lnc-HIST1H2AG-6 and lnc-AIM1-3 were significantly correlated with T2DM (OR = 5.791 and 0.071, respectively, both P = 0.000). Furthermore, the ROC curve showed that the expression of lnc-HIST1H2AG-6 and lnc-AIM1-3 might be used to differentiate patients with T2DM from healthy controls (area under the ROC curve = 0.664 and 0.769, respectively). Conclusion The profiles of lncRNA and mRNA were significantly changed in patients with T2DM. The expression levels of lnc-HIST1H2AG-6 and lnc-AIM1-3 genes were significantly correlated with some features of T2DM, which may be used to distinguish patients with T2DM from healthy controls and may serve as potential novel biomarkers for diagnosis in the future.

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Association between Endoscopic Milk-White Mucosa, Epithelial Intracellular Lipid Droplets, and Histological Grade of Superficial Non-Ampullary Duodenal Epithelial Tumors

Diagnostics ◽

10.3390/diagnostics11050769 ◽

2021 ◽

Vol 11 (5) ◽

pp. 769

Author(s):

Yuko Hara ◽

Kenichi Goda ◽

Shinichi Hirooka ◽

Takehiro Mitsuishi ◽

Masahiro Ikegami ◽

...

Keyword(s):

Lipid Droplets ◽

Histological Grade ◽

Rank Correlation ◽

Intraepithelial Neoplasia ◽

Low Grade ◽

Intracellular Lipid ◽

En Bloc ◽

Spearman’S Rank Correlation ◽

Spearman’S Rank Correlation Coefficient ◽

Positive Rate

We previously reported that superficial non-ampullary duodenal tumors (SNADETs) commonly had a whitish mucosal surface, named milk-white mucosa (MWM). The aim of this study was to evaluate the association of MWM with epithelial intracellular lipid droplets (immunohistochemically stained by adipose differentiation-related protein (ADRP)) and histological tumor grades. We reviewed endoscopic images and the histopathology of SNADETs resected en bloc endoscopically. We analyzed the correlation between the positive rates of endoscopic MWM in preoperative endoscopy and resected specimens, and ADRP-positive rates in the resected specimens. Associations between the MWM-positive rates and tumor grades, high-grade intraepithelial neoplasia (HGIN)/intramucosal carcinoma (IC), and low-grade intraepithelial neoplasia (LGIN) were analyzed. All the 92 SNADETs analyzed were <20 mm and histologically classified into 39 HGIN/IC and 53 LGIN. Spearman’s rank correlation coefficient showed a significant correlation between MWM-positive and ADRP-positive rates (p < 0.001). MWM-positive rates were significantly lower in the HGIN/IC than in the LGIN in preoperative endoscopy (p < 0.001) and resected specimens (p = 0.02). Our results suggest that endoscopic MWM is closely associated with epithelial intracellular lipid droplets and that the MWM-positive rate may be a predictor of histological grade in small SNADETs.

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Correlation between nasopharyngoscopy and cephalometry in the diagnosis of hyperplasia of the pharyngeal tonsils

International Archives of Otorhinolaryngology ◽

10.7162/s1809-97772012000200009 ◽

2012 ◽

Vol 16 (02) ◽

pp. 209-216 ◽

Cited By ~ 1

Author(s):

Luana Berwig ◽

Ana da Silva ◽

Eliane Corrêa ◽

Eliane Serpa ◽

Rodrigo Ritzel

Keyword(s):

Quantitative Study ◽

Fiber Optic ◽

Rank Correlation ◽

Accurate Diagnosis ◽

Cross Sectional ◽

Significance Level ◽

Spearman’S Rank Correlation ◽

Spearman’S Rank Correlation Coefficient ◽

Tonsil Hyperplasia ◽

Pharyngeal Tonsil

Summary Introduction: Hyperplasia of the pharyngeal tonsil is one of the main causes of mouth breathing, and accurate diagnosis of this alteration is important for proper therapeutic planning. Therefore, studies have been conducted in order to provide information regarding the procedures that can be used for the diagnosis of pharyngeal obstruction. Objective: To verify the correlation between nasopharyngoscopy and cephalometric examinations in the diagnosis of pharyngeal tonsil hyperplasia. Method: This was a cross-sectional, clinical, experimental, and quantitative study. Fifty-five children took part in this study, 30 girls and 25 boys, aged between 7 and 11 years. The children underwent nasofibropharyngoscopic and cephalometric evaluation to determine the grade of nasopharyngeal obstruction. The Spearman's rank correlation coefficient at the 5% significance level was used to verify the correlation between these exams. Results: In the nasopharyngoscopy evaluation, most children showed grade 2 and 3 hyperplasia of the pharyngeal tonsil, which was followed by grade 1. In the cephalometry assessment, most children showed grade 1 hyperplasia of the pharyngeal tonsil, which was followed by grade 2. A statistically significant regular positive correlation was observed between the exams. Conclusion: It was concluded that the evaluation of the pharyngeal tonsil hyperplasia could be carried out by fiber optic nasopharyngoscopy and cephalometry, as these examinations were regularly correlated. However, it was found that cephalometry tended to underestimate the size of the pharyngeal tonsil relative to nasopharyngoscopy.

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KNOWLEDGE AND ATTITUDE REGARDING SPACING METHODS OF CONTRACEPTION AMONG PRIMIPARA MOTHERS OF KOLHAPUR

10.36106/ijsr/2533924 ◽

2021 ◽

pp. 70-71

Author(s):

Jyoti Dhanpal Aurwade ◽

Manisha Bijapurkar

Keyword(s):

Rank Correlation ◽

Knowledge Score ◽

Descriptive Study ◽

Attitude Scale ◽

Favorable Attitude ◽

Attitude Score ◽

Chi Square ◽

Poor Knowledge ◽

Spearman’S Rank Correlation ◽

Knowledge And Attitude

Background: Almost half of the pregnancies are usually unintended. Inappropriate spacing between pregnancies can lead to maternal and neonatal complications. Awareness and education plays, a major role in combating this issue. This study was aimed to assess the knowledge and attitude regarding spacing methods of contraception among primipara mothers of Kolhapur. Material and methods: The descriptive study was performed on 110 primipara mothers admitted in hospitals of Kolhapur. A pre-validated study tool consisting of a questionnaire and a Likert attitude scale was used to assess knowledge and attitude of participants. Chi-square and Spearman's rank correlation test was used to nd the association and correlation between variables. Results: Good knowledge score was observed in 5.45% participants whereas, average and poor knowledge score found in 70% and 24.55% of participants respectively. A favorable attitude was noted in 53.6% of mothers and moderately favorable attitudes and unfavorable attitudes were observed in 43.6% and 2.7% mothers respectively. Asignicant positive correlation was observed between the knowledge score and attitude score -05 of primipara mothers (r=0.379, P=4.326e ). A signicant association of knowledge score (P<0.01) and attitude score (P<0.01) with the sociodemography of the participants was observed. Conclusion: Most of the primipara mothers had a favorable attitude regarding spacing methods of contraception but they are lacking in knowledge. The Socio-demography of the participants was signicantly associated with knowledge and attitude scores.

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