Ability to Participate in Social Activities of Rheumatoid Arthritis Patients Compared with Other Rheumatic Diseases: A Cross-Sectional Observational Study

Objectives: To compare the ability to participate in social activities among rheumatoid arthritis patients with other rheumatic disease patients and identify potentially implicated factors. Patients and methods: Between June and November 2019, we consecutively selected patients aged ≥18 years with RA (defined according to ACR/EULAR 2010), SpA (ASAS/EULAR 2010), and SLE (ACR 1997). Main outcome measures: Ability to participate in social roles and activities evaluated using the PROMIS score v2.0 short-form 8a (PROMIS-APS). Secondary outcomes: Participation in social activities according to a series of variables (mobility, depression, satisfaction with social relationships, social isolation, company, emotional support, instrumental support, and support via information). We evaluated the association between the ability to participate in social activities and associated variables using multivariable linear regression analysis. Results: The study population comprised 50 patients with RA (33.1%), 51 patients (33.8%) with SpA, and 50 patients (33.1%) with SLE. The mean PROMIS-APS scores were similar in the three groups. The multivariable analysis for the whole sample showed that the ability to participate in social activities was inversely associated with depression and directly with social satisfaction, mobility, company, and age. The stratified analysis revealed an inverse association between inflammatory activity and ability to participate in social activities in patients with RA and SpA, but not in those with SLE. Conclusion: All patients with RA, SpA, and SLE had a similar ability to participate in social activities. This was associated with other psychosocial factors (social satisfaction, mobility, company, depression) and clinical factors (age and inflammatory activity).

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Poor Dietary Quality Is Associated with Increased Inflammation in Swedish Patients with Rheumatoid Arthritis

Nutrients ◽

10.3390/nu10101535 ◽

2018 ◽

Vol 10 (10) ◽

pp. 1535 ◽

Cited By ~ 11

Author(s):

Linnea Bärebring ◽

Anna Winkvist ◽

Inger Gjertsson ◽

Helen Lindqvist

Keyword(s):

Rheumatoid Arthritis ◽

Disease Activity ◽

Linear Regression Analysis ◽

Dietary Quality ◽

Cross Sectional ◽

Reactive Protein ◽

Multivariable Linear Regression Analysis ◽

Hs Crp ◽

And Gender ◽

Sectional Analysis

The aim was to study whether dietary quality was associated with disease activity and inflammation among patients with rheumatoid arthritis (RA). This cross-sectional analysis included 66 Swedish participants, who each completed a food frequency questionnaire (FFQ) at screening. Food intake was scored by a dietary quality index created by the Swedish National Food Agency. Disease activity was measured as Disease Activity Score 28 (DAS28), based on erythrocyte sedimentation rate (ESR), a patient administered visual analogue scale of perceived global health and the number of tender and swollen joints out of 28 examined. Inflammation was measured as ESR and C-reactive protein (hs-CRP). Associations between dietary quality, disease activity and inflammation were evaluated using multivariable linear regression analysis. High dietary quality (high intake of fish, shellfish, whole grain, fruit and vegetables and low intake of sausages and sweets) was not related to DAS28 (B = −0.02, p = 0.787). However, dietary quality was significantly negatively associated with hs-CRP (B = −0.6, p = 0.044) and ESR (B = −2.4, p = 0.002) after adjusting for body mass index, age, education, smoking and gender. Both hs-CRP and ESR decreased with increasing dietary quality. In conclusion, among patients with RA, high dietary quality was associated with reduced inflammation but not with disease activity.

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High Levels of Psychological Resilience Are Associated With Decreased Anxiety in Inflammatory Bowel Disease

Inflammatory Bowel Diseases ◽

10.1093/ibd/izab200 ◽

2021 ◽

Cited By ~ 1

Author(s):

Alicia Philippou ◽

Priya Sehgal ◽

Ryan C Ungaro ◽

Kelly Wang ◽

Emilia Bagiella ◽

...

Keyword(s):

Regression Analysis ◽

Linear Regression ◽

Linear Regression Analysis ◽

Multivariable Analysis ◽

Cross Sectional Study ◽

Anxiety And Depression ◽

Psychological Resilience ◽

Comorbid Disorders ◽

Cross Sectional ◽

Multivariable Linear Regression Analysis

Abstract Background Anxiety and depression are comorbid disorders with IBD and are associated with poor outcomes. Resilience is an innate but modifiable trait that may improve the symptoms of psychological disorders. Increasing resilience may decrease the severity of these comorbid disorders, which may improve IBD outcomes. The aim of this study was to describe the association between resilience, anxiety, and depression in IBD patients. Methods We performed a cross-sectional study of IBD patients. Patients completed a questionnaire consisting of the Connor-Davidson Resilience Scale (CD-RISC), a measure of resilience, the Generalized Anxiety Disorder 7 (GAD-7), and the Patient Health Questionnaire-9. Primary outcome was severity of anxiety and depression in patients with high resilience. Multivariable linear regression analysis evaluated the association between severity of anxiety and depression and level of resilience. Results A sample of 288 patients was analyzed. Bivariable linear regression analysis showed a negative association between resilience and anxiety (Pearson rho = −0.47; P < .0001) and between resilience and depression (Pearson rho = −0.53; P < .0001). Multivariable linear regression indicated that high resilience is independently associated with lower anxiety and that for every 1-unit increase in CD-RISC, the GAD-7 score decreased by 0.04 units (P = .0003). Unlike anxiety, the association between resilience and depression did not remain statistically significant on multivariable analysis. Conclusions High resilience is independently associated with lower anxiety in IBD patients, and we report a quantifiable decrease in anxiety score severity for every point of increase in resilience score. These findings suggest that IBD patients with higher resilience may have better coping mechanisms that buffer against the development of anxiety.

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Clinic Design and Continuity in Internal Medicine Resident Clinics: Findings of the Educational Innovations Project Ambulatory Collaborative

Journal of Graduate Medical Education ◽

10.4300/jgme-d-14-00358.1 ◽

2015 ◽

Vol 7 (1) ◽

pp. 36-41 ◽

Cited By ~ 16

Author(s):

Maureen D. Francis ◽

Mark L. Wieland ◽

Sean Drake ◽

Keri Lyn Gwisdalla ◽

Katherine A. Julian ◽

...

Keyword(s):

Internal Medicine ◽

Linear Regression Analysis ◽

Internal Medicine Resident ◽

Cross Sectional Study ◽

Analysis Of Covariance ◽

Block Model ◽

Cross Sectional ◽

Educational Innovations ◽

Medicine Resident ◽

Multivariable Linear Regression Analysis

Abstract Background Many internal medicine (IM) programs have reorganized their resident continuity clinics to improve trainees' ambulatory experience. Downstream effects on continuity of care and other clinical and educational metrics are unclear. Methods This multi-institutional, cross-sectional study included 713 IM residents from 12 programs. Continuity was measured using the usual provider of care method (UPC) and the continuity for physician method (PHY). Three clinic models (traditional, block, and combination) were compared using analysis of covariance. Multivariable linear regression analysis was used to analyze the effect of practice metrics and clinic model on continuity. Results UPC, reflecting continuity from the patient perspective, was significantly different, and was highest in the block model, midrange in combination model, and lowest in the traditional model programs. PHY, reflecting continuity from the perspective of the resident provider, was significantly lower in the block model than in combination and traditional programs. Panel size, ambulatory workload, utilization, number of clinics attended in the study period, and clinic model together accounted for 62% of the variation found in UPC and 26% of the variation found in PHY. Conclusions Clinic model appeared to have a significant effect on continuity measured from both the patient and resident perspectives. Continuity requires balance between provider availability and demand for services. Optimizing this balance to maximize resident education, and the health of the population served, will require consideration of relevant local factors and priorities in addition to the clinic model.

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IMPACT OF DIFFERENT LEVELS OF DISEASE ACTIVITY IN PAINFUL PROFILE AND QUALITY OF LIFE IN PEOPLE WITH RHEUMATOID ARTHRITIS

Brazilian Journal of Medicine and Human Health ◽

10.17267/2317-3386bjmhh.v2i1.332 ◽

2014 ◽

Vol 2 (1) ◽

Cited By ~ 1

Author(s):

Selena Márcia Dubois Mendes ◽

Bárbara Liliane Lôbo Queiroz ◽

Larissa Vieira Santana ◽

Abrahão Fontes Baptista ◽

Mittermayer Barreto Santiago ◽

...

Keyword(s):

Quality Of Life ◽

Rheumatoid Arthritis ◽

Disease Activity ◽

Pain Perception ◽

Short Form ◽

Care Service ◽

Cross Sectional ◽

Sf 36 ◽

Different Levels

Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease with impact on increasing the morbidity and mortality rates. Different levels of disease activity (LDA) have been established, however, its impact on pain and quality of life have yet to be been evidenced. The aim of this study was to evaluate the relationship of different levels of disease activity on the painful profile and quality of life (QOL) of patients diagnosed with RA. This was a cross-sectional study, conducted in RA patients attending an Educational Outpatient Care Service in Salvador, Bahia, Brazil. The LDA was defined according to values of Erythrocyte Sedimentation Rate (ESR), Visual Analog Scale (VAS), and number of swollen and sore joints, according to the Disease Activity Score in 28 joints (DAS28). Types of pain were assessed using the Douleur Neuropathique en 4 questions (DN4). To evaluate QOL, the Short Form (36) Health Survey (SF-36) and Health Assessment Questionnaire (HAQ) were applied. The association between LDA, QOL and painful profile was verified using One Way-ANOVA and Bonferroni correction post-test. A high LAD was observed in 67.7% of the 96 patients evaluated in this study. Pain sensation was reported by 94.8 % of participants with 40.6 % reporting it as nociceptive and 80.2% as intense. It was also observed that the higher LAD found the higher was the pain intensity reported (p=0.001) and lower QOL scores (p<0.001). Although the LDA did not correlate with the type of pain (p=0.611), it was correlated with the total score obtained in the QOL from the HAQ (p=0.001). The greatest impact on QOL evaluated through the SF-36 were physical (p<0.001) and functional capacity (p<0.001). In conclusion, RA patients who had high LDA reported more severe pain perception and obtained the lowest scores in the assessment of quality of life.

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The association of multimorbidity, loneliness, social exclusion and network size: findings from the population-based German Ageing Survey

BMC Public Health ◽

10.1186/s12889-019-7741-x ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 3

Author(s):

Kaja Kristensen ◽

Hans-Helmut König ◽

André Hajek

Keyword(s):

Social Exclusion ◽

Short Form ◽

Linear Regression Analysis ◽

Multiple Linear Regression Analysis ◽

Population Based ◽

Network Size ◽

Community Dwelling ◽

Complex Nature ◽

Cross Sectional ◽

Regular Contact

Abstract Background The aim of this study was to examine the association between multimorbidity and (i) loneliness, (ii) social exclusion and (iii) network size, respectively. Methods Cross-sectional data from a German representative sample of community-dwelling adults aged 40 and over was used (N = 7604). Multimorbidity was indicated with the presence of two or more diseases. Self-rated loneliness was assessed with a short form of the validated De Jong Gierveld Loneliness Scale and social exclusion was measured with a validated scale developed by Bude and Lantermann. Counts of important people in regular contact represented the network size of respondents. Results Multimorbidity was present in 68% of the sample. While controlling for potential confounders, multiple linear regression analysis yielded that multimorbidity was associated with increased loneliness (b = 0.08; p < 0.001) and increased social exclusion (b = 0.10; p < 0.01). Multimorbidity was also associated with an increased network size (b = 0.27; p < 0.001). Conclusion While there was an association between multimorbidity and increased social exclusion as well as increased loneliness, regressions also revealed an association between multimorbidity and an increased network size. Although the association between multimorbidity and our outcome measures is weak, its complex nature should be investigated further using a longitudinal approach.

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Trait Emotional Intelligence and Its Correlates in Oman Medical Specialty Board Residents

Journal of Graduate Medical Education ◽

10.4300/jgme-d-18-00388 ◽

2019 ◽

Vol 11 (4s) ◽

pp. 134-140 ◽

Cited By ~ 1

Author(s):

Salim Al Huseini ◽

Mohammed Al Alawi ◽

Hamed Al Sinawi ◽

Naser Al-Balushi ◽

Sachin Jose ◽

...

Keyword(s):

Medical Education ◽

Emotional Intelligence ◽

Short Form ◽

Linear Regression Analysis ◽

Well Being ◽

Medical Specialty ◽

High Income ◽

Trait Emotional Intelligence ◽

Cross Sectional ◽

Specialty Board

ABSTRACT Background As part of the globalization of medical education, residency programs in Oman have adopted competency-based standards by the Accreditation Council for Graduate Medical Education International (ACGME-I). Correctly perceiving the emotions of others and managing one's own emotions are essential to high-quality patient care. Objective We tested the reliability and construct validity of the Trait Emotional Intelligence Questionnaire–Short Form (TEIQue-SF), and assessed trait Emotional Intelligence (EI) in Oman Medical Specialty Board (OMSB) residents in multiple specialties. We explored for correlations with trainees' sociodemographic background data. Methods We conducted a cross-sectional, observational study between February and August 2017. Participants were OMSB residents. We administered the TEIQue-SF and collected sociodemographic data from participants. Multiple linear regression analysis was conducted to identify independent predictors of trait EI. Results The present cohort scored high in the trait EI subscale of Well-being, followed by Sociability, Self-control, and Emotionality. Among sociodemographic factors, female gender and high income were significant predictors of TEIQue-SF's Well-being subscale and high income and living in a rented home were significant predictors of the Sociability subscale. Conclusions This is the first study conducted among medical residents in Oman regarding trait EI and its correlates. Our findings of overall high EI and several socioeconomic predictors echo the literature on the assessment of EI in trainees. The findings add to the evidence of cross-cultural applicability of instruments to measure trait EI, and use assessments of EI in resident selection and education.

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Abstract 17965: Bendopnea is a Marker of Elevated VE/VC02 Slope in Patients With Heart Failure

Circulation ◽

10.1161/circ.132.suppl_3.17965 ◽

2015 ◽

Vol 132 (suppl_3) ◽

Author(s):

Jennifer T Thibodeau ◽

Alberto Dominguez-Rodriguez ◽

Pedro Abreu-Gonzalez ◽

Alejandro Jimenez-Sosa ◽

Juan M Aranda Jr ◽

...

Keyword(s):

Heart Failure ◽

Nyha Class ◽

Linear Regression Analysis ◽

Multivariable Analysis ◽

Study Cohort ◽

Functional Evaluation ◽

Evaluation Standard ◽

Peak Vo2 ◽

Multivariable Linear Regression Analysis ◽

A Prospective Study

Introduction: In patients with advanced heart failure, shortness of breath while bending forwards, e.g. when putting on their shoes, is a recently described symptom termed “bendopnea”. Hypothesis: Whether bendopnea is associated with well validated markers of heart failure severity measured by cardiopulmonary exercise (CPX) testing, such as peak VO2 or VE/VCO2 slope, is not known. Methods: Bendopnea was assessed prior to a CPX in a prospective study of 95 subjects with systolic HF who were referred for functional evaluation. Standard CPX techniques were used including measurement of peak VO2 and VE/VCO2 slope. Multivariable linear regression analysis was performed to adjust the associations of bendopnea and CPX parameters for potential confounders. Results: The study cohort was predominantly male (72%), nonischemic cardiomyopathy (54%), NYHA class 3 or 4 (86%), with a mean age of 55 ± 14 years and LVEF 26 ± 4%. Bendopnea was present in 30 of 95 (31.5%) subjects. The association of bendopnea with key CPX parameters (Table) is shown. Peak VO2 was similar in both groups but patients with bendopnea had a higher VE/VCO2 slope (35.28 ± 2.72 vs 30.31 ± 6.41, P< 0.001) and trended towards having a lower oxygen pulse. The association of bendopnea with VE/VCO2 slope persisted in multivariable analysis. Conclusions: Bendopnea was independently associated with elevated VE/VCO2 slope in advanced HF patients. These data suggest that bendopnea is a marker of HF disease severity.

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Onset And Burden of Lower Limb Lymphedema After Radical Prostatectomy: A Cross-Sectional Study

10.21203/rs.3.rs-620768/v1 ◽

2021 ◽

Author(s):

Manuel Neuberger ◽

Laura Schmidt ◽

Frederik Wessels ◽

Miriam Linke ◽

Carina Müller ◽

...

Keyword(s):

Radical Prostatectomy ◽

Lower Limb ◽

Daily Life ◽

Short Form ◽

Linear Regression Analysis ◽

Complete Regression ◽

Regression Analyses ◽

Compression Stockings ◽

Cross Sectional Survey ◽

Cross Sectional

Abstract ObjectivesTo explore men´s onset and burden of lower limb lymphedema (LLL) after radical prostatectomy (RP) with pelvic lymph node dissection.Patients and methodsA cross-sectional survey-based study was conducted nation-wide and web-based in Germany. Part 1 included 15 multidisciplinary compiled questions with three questions from Short Form 12 Health Survey (SF-12) and WHO activity recommendation, part 2 the validated German Lymph-ICF-Questionnaire (Lymph-ICF-LL). Subgroup comparisons and simple regression analyses were used to identify factors associated with therapy and burden of LLL, followed by multiple regression analyses to explain variance in impairment in the patients’ daily life.Results54 patients completed the survey. Median time of LLL-onset was reported with 2.0 (0.5-9.75) months after RP. 19 patients (35.2%) reported bilateral lymphedema, 28 (51.9%) the use of individually fitted compression stockings (CS), 25 (46.3%) of manual lymphatic drainage (LD) and 26 (48.1%) complete regression.The Lymph-ICF-LL revealed a higher total burden for patients with an active LLL compared to complete regression (total score: 25.5 vs. 11.9, p=0.01) specially for “physical function” (28.3 vs. 12.9, p=0.004) and “mental function” (26.2 vs. 6.7, p<0.001). In multiple linear regression analysis, a higher BMI (β=0.28), lower subjective general health (β=-0.48) and active lymphedema (β =0.28) were significant predictors of higher reported impairments in the Lymph-ICF-LL, accounting for 45.4% of variance.ConclusionMen with LLL after RP with PLND report a significant burden in daily life. Bbasic therapy needs to be offered early. Postoperative onset of LLL is variable, which should be considered when assessing complications after RP.

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Do Physical Activity, Social Cohesion, and Loneliness Mediate the Association Between Time Spent Visiting Green Space and Mental Health?

Environment and Behavior ◽

10.1177/0013916517738563 ◽

2017 ◽

Vol 51 (2) ◽

pp. 144-166 ◽

Cited By ~ 18

Author(s):

Magdalena M. van den Berg ◽

Mireille van Poppel ◽

Irene van Kamp ◽

Annemarie Ruijsbroek ◽

Margarita Triguero-Mas ◽

...

Keyword(s):

Mental Health ◽

Physical Activity ◽

Social Cohesion ◽

Leisure Time ◽

Green Space ◽

Short Form ◽

Linear Regression Analysis ◽

Multiple Mediation ◽

Cross Sectional ◽

Mediation Analyses

This cross-sectional study investigated whether physical activity, social cohesion, and loneliness mediate the association between time spent visiting green spaces and perceived mental health and vitality. Questionnaire data were collected from 3,948 residents from 124 neighborhoods across four European cities. Multilevel linear regression analysis revealed positive, but weak, associations between time spent visiting green space and Medical Outcome Study Short Form (SF-36) mental health and vitality score, which suggest small mental health benefits. Single mediation analyses showed that different indicators of physical activity (total, during leisure time, and walking during leisure time), social cohesion, and loneliness were mediators. Multiple mediation analyses showed that physical activity during leisure time and loneliness may explain about 25% of the relationship. The unmediated part of the association suggests that other mediators may explain the association.

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Health-related quality of life predictors during medical residency in a random, stratified sample of residents

Brazilian Journal of Psychiatry ◽

10.1590/s1516-44462009000200007 ◽

2009 ◽

Vol 31 (2) ◽

pp. 119-124 ◽

Cited By ~ 13

Author(s):

Paula Costa Mosca Macedo ◽

Vanessa de Albuquerque Cítero ◽

Simone Schenkman ◽

Maria Cezira Fantini Nogueira-Martins ◽

Mauro Batista Morais ◽

...

Keyword(s):

Quality Of Life ◽

Short Form ◽

Linear Regression Analysis ◽

Multiple Linear Regression Analysis ◽

Cross Sectional Study ◽

First Year ◽

Cross Sectional ◽

Critical Patients ◽

Almost All

OBJECTIVE: To evaluate the quality of life during the first three years of training and identify its association with sociodemographicoccupational characteristics, leisure time and health habits. METHOD: A cross-sectional study with a random sample of 128 residents stratified by year of training was conducted. The Medical Outcome Study -short form 36 was administered. Mann-Whitney tests were carried out to compare percentile distributions of the eight quality of life domains, according to sociodemographic variables, and a multiple linear regression analysis was performed, followed by a validity checking for the resulting models. RESULTS: The physical component presented higher quality of life medians than the mental component. Comparisons between the three years showed that in almost all domains the quality of life scores of the second year residents were higher than the first year residents (p < 0.01). The mental component scores remained high for third year residents (p < 0.01). Predictors of higher quality of life were: second or third year of residency, satisfaction with the training program, sufficient time for leisure, and care of critical patients for less than 30 hours per week. CONCLUSION: The mental component of quality of life was the most impaired component, indicating the importance of caring for residents' mental health, especially during their first year and when they are overloaded with critical patients.

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