scholarly journals Statistical Unfolding Approach to Understand Influencing Factors for Taxol Content Variation in High Altitude Himalayan Region

Forests ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1726
Author(s):  
Ayushi Gupta ◽  
Prashant K. Srivastava ◽  
George P. Petropoulos ◽  
Prachi Singh

Taxol drugs can be extracted from various species of the taxaceae family. It is an alkaloid (metabolic product) used for the treatment of various types of cancer. Since taxol is a metabolic product, multiple aspects such as edaphic, biochemical, topographic factors need to be assessed in determining the variation in Taxol Content (TC). In this study, both sensor-based hyperspectral reflectance data and absorption-based indices were tested together for the development of an advanced statistical unfolding approach to understand the influencing factors for TC in high altitude Himalayan region. Seriation analysis based on permutation matrix was applied with complete linkage and a multi-fragment heuristic scaling rule along with the common techniques such as Principal Component Analysis (PCA) and correlation to understand the relationship of TC with various factors. This study also tested the newly developed taxol indices to rule out the possibility of overlapping of TC determining bands with the foliar pigment’s wavelengths in the visible region. The result implies that T. wallichiana with a high TC is found more in its natural habitat of deep forest, relating it indirectly to elevation in the case of the montane ecosystem. Taxol is the most varying parameter among the measured variables, followed by hyperspectral Taxol content (TC) indices such as TC 2, TC 5, and carotenoids, which suggests that the indices are well versed to capture variations in TC with elevation.

2020 ◽  
Vol 13 (2) ◽  
pp. 112-121
Author(s):  
Sudiyar . ◽  
Okto Supratman ◽  
Indra Ambalika Syari

The destructive fishing feared will give a negative impact on the survival of this organism. This study aims to analyze the density of bivalves, distribution patterns, and to analyze the relationship of bivalves with environmental parameters in Tanjung Pura village. This research was conducted in March 2019. The systematic random system method was used for collecting data of bivalves. The collecting Data retrieval divided into five research stasions. The results obtained 6 types of bivalves from 3 families and the total is 115 individuals. The highest bivalve density is 4.56 ind / m², and the lowest bivalves are located at station 2,1.56 ind / m²,  The pattern of bivalve distribution in the Coastal of Tanjung Pura Village is grouping. The results of principal component analysis (PCA) showed that Anadara granosa species was positively correlated with TSS r = 0.890, Dosinia contusa, Anomalocardia squamosa, Mererix meretrix, Placamen isabellina, and Tellinella spengleri were positively correlated with currents r = 0.933.


Author(s):  
Syahrial Syahrial ◽  
Eryc Pranata ◽  
Hendri Susilo

Mangrove reforestation is often carried out in various regions or regions, but information about the relationship of environmental factors and the distribution of fauna associations is still very minimal. The Principal Component Analysis (PCA) study on the correlation of environmental factors and the spatial distribution of the molusks community in the Seribu Islands mangrove reforestation area was conducted in March 2014 with the aim of analyzing environmental factors for the diversity and presence of the molusks. Environmental factors are measured insecurely, while the moluccan community is collected by making line transects and plots measuring 10 x 10 m2 and in the size of 10 x 10 m2, a small plot of 1 x 1 m2 is made. The results of the study show that environmental factors are not so different between stations and do not exceed the quality standard for the lives of 4 species of mollusks, where the parameters of aquatic pH are the environmental factors that most influence their distribution.Keywords: environmental factors, distribution, mollusks community, mangrove reforestation, Seribu Islands


2018 ◽  
Vol 27 (3) ◽  
pp. 249-255 ◽  
Author(s):  
Kathleen M Schieffer ◽  
Bryan P Kline ◽  
Leonard R Harris ◽  
Sue Deiling ◽  
Walter A Koltun ◽  
...  

Background & Aims: Diverticulitis is the chronic inflammation of diverticula. Whether the pathophysiology of earlier-onset patients differs from later-onset patients is unknown. We profiled the colonic transcriptomes of these two patient populations to gain insight into the molecular underpinnings of diverticulitis. Methods: We conducted deep RNA sequencing (RNA-seq) on colonic segments surgically resected from earlier-onset (<42 years old, n=13) and later-onset (>65 years old, n=13) diverticulitis patients. We used bioinformatic approaches to cluster the patients based on the relationship of differentially expressed genes and to inform on the molecular pathways that segregated the clusters. Results: Principal component analysis identified three patient clusters; diverticulitis later-onset (DVT-LO), diverticulitis mixed-onset (DVT-MO), and diverticulitis earlier-onset (DVT-EO). The patients comprising DVT-EO, which was the majority of earlier-onset patients, displayed increased expression of anti-viral response genes. This finding was confirmed using an independent weighted co-expression network analysis (WGCNA) of differentially expressed genes. Conclusions: We found that the majority of patients with earlier-onset disease contained elevated expression of host genes involved in the anti-viral response. Thus, susceptibility to a viral pathogen may offer one explanation why some individuals develop diverticulitis at an earlier age.


2018 ◽  
Vol 20 (1) ◽  
pp. 75
Author(s):  
Dimas Haryo Pradana ◽  
Ani Mardiastuti ◽  
Y Yasman

Most of the research about the relationship of birds and figs were conducted at natural habitat. We conducted a research about this relationship at urban habitat in Depok and specifically studied utilization of Ficus benjamina by birds as feeding and nesting tree.  The objective of our research was to describe the F. benjamina utilization by urban birds in Depok.  Scans sampling and nest counting were used during this study.  Our research shows that F. benjamina was used as feeding tree by most of birds which lives at urban habitat in Depok.  Our research also shows that some birds used this fig species as nesting tree.    Key Words : birds, Ficus benjamina, urban, Java


2020 ◽  
Vol 103 ◽  
pp. 19-25
Author(s):  
Tetsumasa Sunada ◽  
Hirotomo Ohuchi ◽  
Shichun Zong ◽  
Toshihiro Kimura

This study considered the relationship between the extent of the Environmental cognition by residents in the coastal fishing area and the physical environment, as ascertained from a questionnaire survey of local residents. The Object is 59 coastal fishing villages (Izu and Bousou peninsula in Japan) in which the sea, a town, and a mountain are realized in one, and has a complicated geographical feature. We have been researched the complexity and metamorphosis patterns of common areas in coastal fishing regions using area drawing method. As a result, villages were classified into five typology of villages based on the relationship between physical environment and landscape recognition. Further, this study analysis Explicate Order and Implicate Order formed from the mutual relationship of the cognitive area and visibility/Invisibility and the clarify characteristic between cognitive area and visibility. We analysis visibility with visible region image using the 3-dimensional shade picture which applied the inverse-square damping which is an approximation to man's visual recognition and which is obtained from a spread of light. From the above analysis, correlativity of cognitive area and visibility by landscape cognition of residents was shown and its Composition was revealed.


2021 ◽  
Vol 22 (2) ◽  
Author(s):  
IPANNA ENGGAR SUSETYA ◽  
Mohammad Basyuni ◽  
DESRITA DESRITA ◽  
ARIDA SUSILOWATI ◽  
TADASHI KAJITA

Percut Sei Tuan is a coastal area on the east coast of North Sumatra which has a lot of natural resource potential, one of them which is green mussels (Perna viridis). Green mussels have many benefits, namely for consumption, cultivation and bioindicator. This study aimed to determine the density, habitat location, growth pattern, frequency distribution of green mussels, physical-chemical parameters of water, a substrate of the bottom waters, and the relationship of green clams density to water and substrate parameters. The study was conducted in July-September 2020. Data analysis included density, the relationship of total length and weight of green mussels, the frequency distribution of shell lengths, and Principal Component Analysis (PCA). The results showed that the density of green mussels at stations I, II, and III were 352 ind/m2, 3 ind/m2, and 1 ind/m2, respectively. The relationship between the length and weight of green shells shows that the growth was negative allometric. The water condition, seen from the physical, chemical, and substrate parameters, was still suitable for P. viridis. Water and substrate parameters that were positively related to the density of green mussels were water temperature, nitrate, phosphate, C-organic, percentage of silt and clay. Parameters that were negatively related were salinity, pH, and percentage of sand in the bottom substrate. The present study suggested that Station I was an appropriate area for the growth and reproduction of green mussels.


2019 ◽  
Vol 34 (6) ◽  
pp. 903-903
Author(s):  
M Gukasyan ◽  
J Moses ◽  
K Greenman

Abstract Objective We investigated the factorial relationship of the six categories of memory errors of the BVRT to the four factorial variables of the WAIS to determine the relationship between cognitive and nonverbal memory variables. Methods A sample of 134 diagnostically mixed ambulatory American Veteran patients with a wide variety of mixed neuropsychiatric diagnoses and with or without general medical problems who had completed the WAIS-3, and the BVRT were examined. There were no demographic or diagnostic exclusion criteria. Results The 6 types of BVRT memory errors (omissions, distortions, perseverations, rotations, misplacements, and size errors) were factored using principal component analysis. The four WAIS 3 and six BVRT components were jointly factored to examine for systematic relationships between memory and cognitive domains. The analysis identified specific factorial relationships of BVRT error type to each of the four factorial components of the WAIS. POI was related to rotation errors, VCI was related to size errors, PSI specifically related to omissions and WMI to distortions. Misplacement and perseveration errors were related to each other but not to factorial constructs of the WAIS. Conclusions There are specific and robust relationships among BVRT errors and dimensional cognitive variables.


1988 ◽  
Vol 64 (5) ◽  
pp. 1878-1884 ◽  
Author(s):  
J. L. Beard ◽  
J. D. Haas ◽  
D. Tufts ◽  
H. Spielvogel ◽  
E. Vargas ◽  
...  

Thirty-seven young adult male highland residents at 3,600–4,100 m in La Paz, Bolivia, performed short-duration cycle ergometry at 60, 80, and 100% of maximal voluntary O2 consumption (VO2max). Three groups of subjects representing the high-altitude population mean hemoglobin (Hb), the 10th percentile Hb, and below the 1st percentile were examined to test the hypothesis that the relationship of exercise performance to Hb concentration is similar to those relationships established at low altitude. Anemic individuals (n = 8) had 23% lower voluntary VO2max and 28% lower maximal work loads compared with controls (n = 17) or marginally anemic subjects (n = 12) although the relationship of VO2 to work load was similar. Anemic individuals maintained significantly higher arterial O2 partial pressures and Hb saturations during heavy exercise (90 +/- 0.5 vs. 85 +/- 0.6%) in conjunction with a greater heart rate up to maximal effort. A significantly decreased erythrocyte 2,3-diphosphoglycerate (2,3-DPG)-to-Hb molar ratio (0.70 +/- 0.04 vs. 1.12 +/- 0.06), suggestive of a left-shifted dissociation curve in anemics, is in contrast to the expected right-shifted curve. Moderate anemics were similar to controls. Anemic individuals did not differ in arterial lactate concentration from controls at absolute work loads; anemics had significantly lower arterial lactate concentrations at maximal effort than controls with no differences in the work load-to-lactate relationship. In conclusion, O2 transport during exercise at high altitude seems unaffected by the Hb concentrations as low as the 10th percentile of the population mean.(ABSTRACT TRUNCATED AT 250 WORDS)


2019 ◽  
Vol 6 (2) ◽  
pp. 23
Author(s):  
Hina Munir ◽  
Cai Jianfeng ◽  
Wang Miao ◽  
Sidra Ramzan

Human capital variables (such as practical learning, education and experience) affect cognitive decision making abilities of individuals which permit them to identify entrepreneurial opportunities. Therefore, this study aims to establish an integrated model considering the theory of planned behavior (TPB) and human capital variables considering Pakistan as a sample, especially targeting IT major students. Data for the study were collected from 227 IT major students from seven universities from different provinces of Pakistan. Principal component analysis and hierarchical multiple regression analysis are used for data analysis. The findings of the study confirm the validity of TPB model in predicting entrepreneurial intentions among IT major students. This study further confirms the effect of human capital variables within TPB framework and demonstrates that prior entrepreneurial exposure (PEE) and prior familial exposure (PFE) have an impact on attitude towards entrepreneurship. Furthermore, the relationship of PEE and PFE in predicting entrepreneurial intentions was found insignificant and significant respectively. This is one of the first studies which explore entrepreneurial intentions among IT major students regarding a developing country. Furthermore, this study provides valuable insights to practitioners and educators in Pakistan for consideration of human capital variables’ influence on entrepreneurial behavior and entrepreneurial intentions among IT major students. 


1974 ◽  
Vol 52 (8) ◽  
pp. 1947-1972
Author(s):  
K. A. Kershaw

The relationship of the sedge meadows lying between raised-beach ridges at the Pen Island site in NW Ontario is described using principal-component analysis. Three major trends are detected following moss hummock formation, depth of water table, and pH. The data also show a progressive sequence from the young meadows with few hummocks and high pH to the older meadows where marked hummock formation has occurred and where the overall pH is lower. Six noda have subsequently been extracted as the central plant associations characteristic of the area.


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