Dynamics of a Gel-Based Artificial Tear Film with an Emphasis on Dry Disease Treatment Applications
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This paper discusses the spreading of gel-based ophthalmic formulation on the cornea surface assumed to be flat. We show that gel-based formulations exhibit rheological behaviors that the Herschel–Bulkley model can describe. The continuity and momentum equations are solved numerically using the monofluid formulation and the volume-of-fluid (VOF) method. We investigated the influence of the rheological properties, namely the consistency, the yield stress, and the flow behavior index, on the spreading of a gel-based artificial tear over the cornea surface. We propose optimal values of these properties for efficient gel-based artificial tears.
1999 ◽
Vol 5
(1)
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pp. 59-65
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2019 ◽
Vol 15
(4)
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pp. 437-441
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2012 ◽
Vol 430-432
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pp. 301-305
2006 ◽
Vol 2
(1)
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