scholarly journals Dynamics of a Gel-Based Artificial Tear Film with an Emphasis on Dry Disease Treatment Applications

Gels ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. 215
Author(s):  
Hamza Mehdaoui ◽  
Hamid Ait Abderrahmane ◽  
Clement de Loubens ◽  
Faïçal Nait Bouda ◽  
Sofiane Hamani

This paper discusses the spreading of gel-based ophthalmic formulation on the cornea surface assumed to be flat. We show that gel-based formulations exhibit rheological behaviors that the Herschel–Bulkley model can describe. The continuity and momentum equations are solved numerically using the monofluid formulation and the volume-of-fluid (VOF) method. We investigated the influence of the rheological properties, namely the consistency, the yield stress, and the flow behavior index, on the spreading of a gel-based artificial tear over the cornea surface. We propose optimal values of these properties for efficient gel-based artificial tears.

1999 ◽  
Vol 5 (1) ◽  
pp. 59-65 ◽  
Author(s):  
T. Lo ◽  
R.G. Moreira ◽  
E. Castell-Pérez

The rheological properties of cooked corn meal dough were determined by squeezing flow, steady shear, and dynamic shear rheological methods. Under biaxial extension, the material exhibited strain- thinning behavior and the normal stress difference could be modeled as a function of biaxial strain rate, with a flow behavior index, n, of 0.38-0.52 and the biaxial consistency coefficient, Kb, ranging from 4.63 x 107 to 9.75 x 107 Pa.s". Steady and dynamic shear studies suggest that the dough exhibits shear-thinning behavior at a shear rate range of 1-40 s-1 and more viscous-like characteristics under dynamic conditions (0.5-10 s-1 frequency). Particle size distribution of the corn meal may affect some of the rheological properties ( K b, K, n) of the cooked dough. Further research is necessary to establish correlation between material variation and product quality for improvement of processes such as extrusion, baking or frying.


2019 ◽  
Vol 15 (4) ◽  
pp. 437-441 ◽  
Author(s):  
Vasiliki Lagouri ◽  
Georgia Dimitreli ◽  
Aikatarini Kouvatsi

Background: Oxidation reactions are known to shorten the shelf life and cause damage to foods rich in fat, such as dairy products. One way to limit oxidation and increase the shelf life of fermented dairy products is to use natural antioxidants. The aim of this study was to examine the effect of adding pomegranate extracts in the antioxidant properties, rheological characteristics and the storage stability of the fermented product of kefir. Methods: The Pomegranate Juice (PGJ) and Peel Extracts (PGPE) (5%, 10% w/v) were added to kefir and the antioxidant properties were evaluated by using the methods of radical scavenging activity (DPPH) and Ferric Reducing Antioxidant Power Activity (FRAP). Spectrophotometric and instrumental methods were used to determine the Total Phenols (TPs), pH values, viscosity and flow behavioral index values of enriched with pomegranate kefir samples. The same properties were tested when kefir samples stored at 4°C for 7, 14, 21 and 28 days. Results: The addition of PGJ and PGPE results in an increase in the antioxidant activity (DPPH, FRAP) and total phenol content (TPs) of kefir samples. Increasing the concentration of the added PGJ and PGPE, results in an increase in the TP content and the DPPH activity of kefir. As far as the storage time is concerned, the results showed an increase in the amount of TP at 7th day and a reduction in the DPPH activity in the 14th day of storage. In contrary to the DPPH method, the increase in storage time has resulted in a reduction in antioxidant activity by the FRAP method. The addition of PGJ and PGPE in kefir results in a decrease in pH values while the pH of kefir samples increased during storage at 4°C for 28 days. The addition of PGJ and PGPE to kefir samples results to a decrease in viscosity and an increase in the flow behavior index. Increasing storage time results in increased flow behavior index of kefir samples. Conclusion: The addition of PGJ and PGPE increased the antioxidant activity and total phenols of the kefir product and preserved its properties during the total storage time of 28 days at 4°C.


Author(s):  
Cunlu Zhao ◽  
Chun Yang

Electroosmotic flow of power-law fluids in a slit channel is analyzed. The governing equations including the linearized Poisson–Boltzmann equation, the Cauchy momentum equation and the continuity equation are solved to seek analytical expressions for the shear stress, dynamic viscosity and velocity distributions. Specifically, exact solutions of the velocity distributions are explicitly found for several special values of the flow behavior index. Furthermore, with the implementation of an approximate scheme for the hyperbolic cosine function, approximate solutions of the velocity distributions are obtained. In addition, a mathematical expression for the average electroosmotic velocity is derived for large values of the dimensionless electrokinetic parameter, κH, in a fashion similar to the Smoluchowski equation. Hence, a generalized Smoluchowski velocity is introduced by taking into account contributions due to the finite thickness of the electric double layer and the flow behavior index of power-law fluids. Finally, calculations are performed to examine the effects of κH, flow behavior index, double layer thickness, and applied electric field on the shear stress, dynamic viscosity, velocity distribution, and average velocity/flow rate of the electroosmotic flow of power-law fluids.


Author(s):  
Florina A. SILAGHI ◽  
Alessandro GIUNCHI ◽  
Angelo FABBRI ◽  
Luigi RAGNI

The control of ice cream powder mixture production is carried out evaluating the ice cream liquid phase. The present study was conduced on ice cream and unfrozen liquid phase in order to indirectly evaluate the rheological properties by measuring the powder mixture. The calibration set was formed by samples with different percentage of thickeners, maintaining constant the concentration of the other remaining compounds. After the NIR acquisitions the powders were mixed with warm milk, blended and than settled in order to obtain the unfrozen liquid phase needed for the rheological measurements. For each recipe three batches were prepared. The flow curves were evaluated by using the Ostwald de Waele’s equation and the goodness of fit was evaluated by the R2, which was above 0.95. Predictive models of rheological parameters were set up by means of PLS regressions in order to predict the consistency coefficient (K) and the flow behavior index (n) from spectral acquisitions. High correlation of calibration was found for both parameters and NIR spectra obtaining R2 of 0.884 for K and 0.874 for n. The good prediction of the models encourages applying them to reduce significantly the time of the powder mixing control during production.


2008 ◽  
Vol 18 (3) ◽  
pp. 34482-1-34482-11 ◽  
Author(s):  
Vassilios C. Kelessidis ◽  
Roberto Maglione

AbstractA methodology is presented to invert the flow equation of a Herschel-Bulkley fluid in Couette concentric cylinder geometry, thus enabling simultaneous computation of the true shear rates, γ̇HB, and of the three Herschel-Bulkley rheological parameters. The errors made when these rheological parameters are computed using Newtonian shear rates, γ̇N, as it is normal practice by research and industry personnel, can then be estimated. Quantification of these errors has been performed using narrow gap viscometer data from literature, with most of them taken with oil-field rheometers. The results indicate that significant differences exist between the yield stress and the flow behavior index computed using γ̇HB versus the parameters obtained using γ̇N and this is an outcome of the higher γ̇HB values. Predicted true shear rates and rheological parameters are in very good agreement with results reported by other investigators, who have followed different approaches to invert the flow equation, both for yield-pseudoplastic and power-law fluids.


Materials ◽  
2018 ◽  
Vol 11 (6) ◽  
pp. 917 ◽  
Author(s):  
Chao Li ◽  
Shaopeng Wu ◽  
Guanyu Tao ◽  
Yue Xiao

Author(s):  
Suresh Kumar Patel ◽  
Subrata Kumar Majumder

The packed bed columns with non-Newtonian liquid are increasing importance as a simple and inexpensive means of achieving yield of different chemical and biochemical processes though their hydrodynamic behavior is complex and not yet fully understood. In this article non-Newtonian flow behavior on frictional pressure was investigated in packed bed within a range of liquid velocity 0.004-0.04 m/s. The frictional pressure loss in non-Newtonian liquid system has been analyzed by modified Ergun equation. The modification of the Ergun equation is incorporated with the flow behavior index of non-Newtonian liquid. The degree of frictional pressure loss decreases with increase in flow behavior index. A correlation has been developed to interpret the degree of effect on the frictional pressure loss. The correlation may be useful for further understanding and scale-up of the packed bed column for its industrial application.


2012 ◽  
Vol 430-432 ◽  
pp. 301-305
Author(s):  
Li Wen Tan ◽  
Dong Mei Xu ◽  
Quan Ji ◽  
Bing Bing Wang ◽  
Yan Zhi Xia

Rheological properties of blend spinning solution of sodium alginate and TiO2 nanoparticles (SA/nano-TiO2) were investigated. The rheological parameters, structural viscosity index (Δη) and flow activation energy (Eη) of spinning solutions were calculated. The results reported that the blend spinning solutions were non-newtonian fluids. The apparent viscosity, consistency index (k) and Eη increased with increasing nano-TiO2 content in SA spinning solution, but the degradation degree of apparent viscosity decreased, flow behavior index (n) only slightly decreased and the Δη had no significantly change. The apparent viscosity (ηa) of spinning solutions could be regulated by changing temperature under 50oC. Blend spinning solution had good stability and practical applicability.


Author(s):  
Charles Windson Isidoro Haminiuk ◽  
Maria-Rita Sierakowski ◽  
Giselle Maria Maciel ◽  
José Raniere Mazile Bezerra Vidal ◽  
Ivanise Guilherme Branco ◽  
...  

Rheological parameters of Butia pulp were determined at different temperatures using a concentric cylinder Haake Rotovisco rheometer, model RV-20, with measurement system ZA-30. Butia pulp was found to exhibit non-Newtonian, pseudoplastic behavior at all temperatures and the rheological parameters were adequately described by the Herschel-Bulkley model. Yield stress, flow behavior index, and consistency coefficient were significantly affected by temperature. The yield stress decreased exponentially with process temperature and ranged between 36.60 and 21.70 Pa. Apparent viscosity calculated through the Herschel-Bulkley model decreased with an increase in temperature. The Arrhenius model gave a good description of temperature effect on apparent viscosity of the pulp.


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