scholarly journals Differences and Similarities in Diabetes Research between China and the USA

2019 ◽  
Vol 16 (16) ◽  
pp. 2989
Author(s):  
Hong Fan ◽  
Sheetal Bhurke ◽  
Guizhen Jia ◽  
Fujian Song
Keyword(s):  
Diabetes Mellitus ◽  
Developed Countries ◽  
Effective Control ◽  
Diabetes Research ◽  
High Quality Research ◽  
Middle Income ◽  
Middle Income Countries ◽  
Management Interventions ◽  
The Usa ◽  
Control And Management

Diabetes mellitus is one of the major non-communicable diseases (NCD) with increasing prevalence in China. There is a lack of high-quality research focusing on prevention and management of diabetes in low and middle income countries (LMICs) compared to developed countries. This comparative study aims to describe the characteristics of diabetes research conducted in China and the USA. The study included 800 studies on diabetes mellitus from both countries. Compared with studies in the USA, studies in China were more likely to be laboratory-based primary research (50.5% versus 30.8%), more likely to use animal subjects (47% versus 27.5%), more likely to focused on risk factors (22.7% versus. 14.7%), more likely to be case-controlled studies (17.7% versus 10.0%), and more likely to evaluate pharmacological treatments (36.5% versus 20.7%). Further, compared with studies in the USA, studies in China were less likely to involve patients (42.7% versus 60.7%), less likely to be clinical trials (6.2% versus 14.5%), less likely to be cohort studies (8.8% versus. 26.0%), and less likely to evaluate disease management interventions (3.3% versus 13.3%). Clinical studies in China should be more patient-based to facilitate more effective control and management of diabetes.

scholarly journals Infectious diseases acquired by international travellers visiting the USA†

2018 ◽  
Vol 25 (1) ◽  
Author(s):  
Rhett J Stoney ◽  
Douglas H Esposito ◽  
Phyllis Kozarsky ◽  
Davidson H Hamer ◽  
Martin P Grobusch ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Descriptive Analysis ◽  
Low Frequency ◽  
Developed Countries ◽  
Middle Income ◽  
Middle Income Countries ◽  
International Tourist ◽  
Clinical Diagnoses ◽  
The Usa ◽  
Systemic Infections

Abstract Background Estimates of travel-related illness have focused predominantly on populations from highly developed countries visiting low- or middle-income countries, yet travel to and within high-income countries is very frequent. Despite being a top international tourist destination, few sources describe the spectrum of infectious diseases acquired among travellers to the USA. Methods We performed a descriptive analysis summarizing demographic and travel characteristics, and clinical diagnoses among non-US-resident international travellers seen during or after travel to the USA at a GeoSentinel clinic from 1 January 1997 through 31 December 2016. Results There were 1222 ill non-US-resident travellers with 1393 diagnoses recorded during the 20-year analysis period. Median age was 40 (range 0–86 years); 52% were female. Patients visited from 63 countries and territories, most commonly Canada (31%), Germany (14%), France (9%) and Japan (7%). Travellers presented with a range of illnesses; skin and soft tissue infections of unspecified aetiology were the most frequently reported during travel (29 diagnoses, 14% of during-travel diagnoses); arthropod bite/sting was the most frequently reported after travel (173 diagnoses, 15% after-travel diagnoses). Lyme disease was the most frequently reported arthropod-borne disease after travel (42, 4%). Nonspecific respiratory, gastrointestinal and systemic infections were also among the most frequently reported diagnoses overall. Low-frequency illnesses (<2% of cases) made up over half of diagnoses during travel and 41% of diagnoses after travel, including 13 cases of coccidioidomycosis and mosquito-borne infections like West Nile, dengue and Zika virus diseases. Conclusions International travellers to the USA acquired a diverse array of mostly cosmopolitan infectious diseases, including nonspecific respiratory, gastrointestinal, dermatologic and systemic infections comparable to what has been reported among travellers to low- and middle-income countries. Clinicians should consider the specific health risks when preparing visitors to the USA and when evaluating and treating those who become ill.

Endocrine and Therapeutic Basis of Diabetes Mellitus Therapy

2019 ◽  
Vol 12 (2) ◽  
pp. 4441-4452
Author(s):  
Mayank Kulshreshtha ◽  
Pragati Srivastava ◽  
Dharamveer Panjwani
Keyword(s):  
Diabetes Mellitus ◽  
Microvascular Complications ◽  
Developed Countries ◽  
Scientific Data ◽  
World Health ◽  
Middle Income ◽  
Middle Income Countries ◽  
Daily Exercise ◽  
Sugar Levels ◽  
Health Organization

This review article describes the role of hormones, microvascular complications, pharmacological and non-pharmacological treatments and precautions of diabetes therapy. Diabetes mellitus (DM) is a chronic, lifelong condition that affects ability to use the energy found in food. According to World Health Organization (WHO), it is estimated 422 million adults are suffered with DM up to latest 2016 data.  It occurs throughout the world but is more common in the more developed countries. Increase in prevalence is occurring in low- and middle-income countries including in Asia and Africa, where most patients will probably be found by 2030. The WHO estimates that diabetes resulted in 1.5 million deaths in 2012, making it the 8th leading cause of death. We summarized the published scientific data and new development in the field of diabetes with a search of PubMed, Google scholar, med know and other online resources.  Various hormones play an important role in which insulin has a more importance in DM. Pharmacological treatment included various side effects while herbal drugs are found to be safe. Diet and exercise are the excellent key points to cure the disease. Avoid high sugar diet and various foods whose sugar levels are high should be avoided at the age 40.  Overall, better knowledge, balanced life style, and daily exercise are the excellent treatment of diabetes and effective glucose control.   

scholarly journals Designing the next generation of implementation research training for learners in low- and middle-income countries

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Michael J. Penkunas ◽  
Shiau Yun Chong ◽  
Emma L. M. Rhule ◽  
Evangelia Berdou ◽  
Pascale Allotey
Keyword(s):  
Implementation Research ◽  
Research Training ◽  
Training Model ◽  
Learning By Doing ◽  
Health Interventions ◽  
System Level ◽  
High Quality Research ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

AbstractEfficacious health interventions tested through controlled trials often fail to show desired impacts when implemented at scale. These challenges can be particularly pervasive in low- and middle-income settings where health systems often lack the capacity and mechanisms required for high-quality research and evidence translation. Implementation research is a powerful tool for identifying and addressing the bottlenecks impeding the success of proven health interventions. Implementation research training initiatives, although growing in number, remain out of reach for many investigators in low- and middle-income settings, who possess the knowledge required to contextualize challenges and potential solutions in light of interacting community- and system-level features. We propose a realigned implementation research training model that centers on team-based learning, tailored didactic opportunities, learning-by-doing, and mentorship.

scholarly journals Characteristics and circumstances of falls leading to severe fractures in elderly people in Rio de Janeiro, Brazil

2009 ◽  
Vol 25 (2) ◽  
pp. 455-459 ◽  
Author(s):  
Evandro Silva Freire Coutinho ◽  
Kátia Vergetti Bloch ◽  
Laura C. Rodrigues
Keyword(s):  
Risk Factors ◽  
Elderly People ◽  
Rio De Janeiro ◽  
Developed Countries ◽  
Case Control ◽  
Demographic Variables ◽  
Case Control Studies ◽  
Middle Income ◽  
Middle Income Countries ◽  
Gender And Age

The circumstances associated with falls among elderly people have been well described in some developed countries, but little is known about such accidents in middle-income countries. The aim of this paper is to report the circumstances and characteristics associated with falls leading to severe fractures among elderly people living in Rio de Janeiro, Brazil. Cases were obtained from two case-control studies on risk factors for severe fractures due to falls among individuals 60 years or older. Fallers were stratified according to clinical and socio-demographic variables and circumstances of the accident. Women comprised three-fourths of the sample. The femur was the most frequently fractured bone, more common among individuals over 70 years of age. Most falls occurred at home, between 6:00 AM and 6:00 PM, but the rooms where they occurred differed according to gender and age. Most individuals did not attribute their falls to tripping or slipping. This sample's data did not differ substantially from studies in developed countries.

scholarly journals Research and Publication from Developing Countries

2020 ◽  
Vol 42 (3) ◽  
Author(s):  
Mohan R Sharma
Keyword(s):  
Developing Countries ◽  
Burden Of Disease ◽  
Disease Burden ◽  
Developed Countries ◽  
Publishing Research ◽  
Economic Factors ◽  
Middle Income ◽  
High Burden ◽  
Middle Income Countries ◽  
The Developed Countries

In 2002, Richard Smith wrote an editorial, “publishing research from developing countries” in the Journal “Statistics in Medicine” highlighting the importance of research and publication from the developing countries (DCs).1 In that article, he mentioned the disparity in research and publication between the developed and developing countries. Almost two decades on, the problem still largely remains the same. It is estimated that more than 80% of the world’s population lives in more than 100 developing countries.2 In terms of disease burden, the prevalence and mortality from diseases in the low and middle-income countries are disproportionately high compared to developed countries.3 Although there is a high burden of disease, we base our treatment inferring results from research and publication from the developed countries which may not be fully generalizable due to geographical cultural, racial, and economic factors. This is where the problem lies.

Migraine and Stress – An Explorative Cross-Country Study of External Stress Factors

2020 ◽  
Author(s):  
Irene van Staveren
Keyword(s):  
Low Income ◽  
Developed Countries ◽  
Ordinary Least Squares ◽  
External Stress ◽  
Stress Factors ◽  
Middle Income ◽  
Middle Income Countries ◽  
Proxy Variables ◽  
Modifiable Factors ◽  
Cross Country

Abstract BackgroundAccording to the Global Burden of Disease 2016 project, migraine ranks first for 15-49 years and second for all ages. The project has reported no significant relation with socio-economic status of a country. To the contrary, migraine ranks first for all ages in low- and middle-income countries suffering from civic unrest and conflict. This raises the question whether external stress factors may be correlated with migraine years lived with disability (YLD).MethodsIn the absence of cross-country studies on migraine and stress, this is a unique exploratory study. The analysis uses two country groups: developed countries (including some middle-income countries) and developing (middle- and low-income) countries. For the first group, proxy variables for stress are included that relate to flexible and highly competitive labour markets (productivity and unemployment), whereas for the second group, proxy variables are used that relate to conflict and migration. The data were analysed with multiple ordinary least squares cross-section regressions.ResultsThe results show a positive relationship between the stress variables on the one hand and migraine YLD on the other hand for both country groups. Almost all results are statistically significant at p<0.01.ConclusionsThe findings from the exploratory cross-country analysis suggest that societal stress factors may be potential candidates for modifiable factors for the prevalence and severity of migraine at the country level.

The Evolution of the Digital Divide across Developing Countries

2013 ◽  
pp. 1554-1570
Author(s):  
Nicoletta Corrocher ◽  
Anna Raineri
Keyword(s):  
Developing Countries ◽  
Digital Divide ◽  
Low Income ◽  
Competition Policy ◽  
Developed Countries ◽  
Policy Implications ◽  
Effective Strategy ◽  
Middle Income ◽  
Middle Income Countries ◽  
Emerging Patterns

This chapter aims at investigating the evolution of the digital divide within a set of developing countries between the years 2000 and 2005. In doing so, it moves away from the traditional analysis of the digital divide, which compares developed countries and developing countries, and examines the existing gap within a relatively homogeneous group of countries. On the basis of the theoretical and empirical contributions from scholars in different disciplines, we select a series of socioeconomic and technological indicators and provide an empirical assessment of the digitalization patterns in a set of 51 low income and lower-middle income countries. By means of cluster analysis techniques, we identify three emerging patterns of the digital divide and derive a series of policy implications, related to the implementation of an effective strategy to reduce digital backwardness. The characteristics of each pattern of digitalization can be also usefully employed to understand whether past interventions, especially in the area of competition policy, have been successful in addressing country-specific issues.

The FINDRISC questionnaire capacity to predict diabetes mellitus II, arterial hypertension and comorbidity in women from low-and-middle-income countries

2019 ◽  
Vol 41 (2) ◽  
pp. 205-226
Author(s):  
María García Rodríguez ◽  
Manuel Romero Saldaña ◽  
José Manuel Alcaide Leyva ◽  
Rafael Moreno Rojas ◽  
Guillermo Molina-Recio
Keyword(s):  
Diabetes Mellitus ◽  
Arterial Hypertension ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

Logistics Cost Dynamics in International Business: A Causal Approach

2020 ◽  
Vol 55 (4) ◽  
pp. 478-495
Author(s):  
Ashutosh Kar ◽  
Pratyay Ranjan Datta
Keyword(s):  
International Business ◽  
Vital Role ◽  
Logistics Cost ◽  
Middle Income ◽  
Jel Codes ◽  
Middle Income Countries ◽  
The Usa ◽  
Causal Approach ◽  
The Cost ◽  
The Impact

The cost of logistics plays a vital role in the pricing of goods in international trade. Besides, the recent imposition of additional tariff by even upper-middle income countries such as the USA, China etc., has led to an increase in the total landed cost of goods. However, a seller has no option but to adapt to changing tariff requirements and can articulate only the logistics cost to a certain extent. This aspect requires an understanding of the logistics cost dynamics in international business. Since a higher volume of goods moves by marine transportation, this study focusses on the same. In this article, authors have attempted to establish a statistically significant relationship between prices and other factors like fuel, number of vessels, freight, and weight value ratio. The paper introduces a logistics-coefficient to indicate the extent of integration of logistics activities to keep the total-landed-cost (TLC) unchanged. Finally, the author proposes the system dynamics model to study the impact of changes in any one or some or all these factors on the price of the product. This model will enable the global firm to decide the entry and exit in the market. JEL Codes: F23

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