scholarly journals Daily Medication Management and Adherence in the Polymedicated Elderly: A Cross-Sectional Study in Portugal

Author(s):  
Daniel Gomes ◽  
Ana Isabel Placido ◽  
Rita Mó ◽  
João Lindo Simões ◽  
Odete Amaral ◽  
...  

The presence of age-related comorbidities prone elderly patients to the phenomenon of polypharmacy and consequently to a higher risk of nonadherence. Thus, this paper aims to characterize the medication consumption profile and explore the relationship of beliefs and daily medication management on medication adherence by home-dwelling polymedicated elderly people. A questionnaire on adherence, managing, and beliefs of medicines was applied to polymedicated patients with ≥65 years old, in primary care centers of the central region of Portugal. Of the 1089 participants, 47.7% were considered nonadherent. Forgetfulness (38.8%), difficulties in managing medication (14.3%), concerns with side effects (10.7%), and the price of medication (9.2%) were pointed as relevant medication nonadherence-related factors. It was observed that patients who had difficulties managing medicines, common forgetfulness, concerns with side effects, doubting the need for the medication, considered prices expensive, and had a lack of trust for some medicines had a higher risk of being nonadherent. This study provides relevant information concerning the daily routine and management of medicines that can be useful to the development of educational strategies to promote health literacy and improve medication adherence in polymedicated home-dwelling elderly.

2020 ◽  
Vol 6 (1) ◽  
pp. 39-45
Author(s):  
Reny Sulistyowati ◽  
Agnes Dewi Astuti

The level of adherence usually decreases in patients with chronic conditions compared to acute conditions; this is related to the long-term nature of chronic disease due to the most rapid decrease in adherence after the first 6 months of therapy. The decline in compliance not only resulted in poor health outcomes but also had a significant impact on health costs. The purpose of this study was to determine family support for medication adherence in type 2 DM patients. This study used descriptive correlational using a cross-sectional study approach of 100 respondents. Patient demographic data and family support were obtained using a questionnaire while the level of compliance used Morisky Medication Adherence Scales. The results show that there is a relationship between family support and medication adherence in patients with type 2 diabetes, which is viewed from 4 dimensions: appreciation support, emotional support, information support, and instrumental support. Support from family can improve medication adherence in type 2 DM patients.


2020 ◽  
pp. 105477382098138
Author(s):  
Fatma Ilknur Cinar ◽  
Şule Mumcu ◽  
Betülay Kiliç ◽  
Ülkü Polat ◽  
Bilge Bal Özkaptan

Low medication adherence is one of the leading causes that affect the achievement of target levels for hypertension. Identifying modifiable factors associated with low adherence is crucial. This study aims to assess medication adherence and the role of beliefs about medicines on medication adherence among hypertensive patients.This cross-sectional study was conducted with 200 hypertension patients.Data were collected using the Morisky-Green-Levine Medication Adherence Scale, and the Beliefs about Medicines Questionnaire [BMQ-Turkish Translation (BMQ-T)]. It was found that the BMQ-T subscales of Specific Concern (β = 0.358, p = .027) and General Overuse (β = 0.552, p = .011) had an independent predictor effect on medication adherence scores. In this study, the patients who thought that drugs were overused and had concerns about this were seen to be less adherent with the medication. With regard to patients who use antihypertensive drugs but have uncontrolled blood pressure, their beliefs about drugs should not be ignored when evaluating adherence with drug therapy.


2016 ◽  
Vol 9 (5) ◽  
pp. 286 ◽  
Author(s):  
Reza Esmaeili ◽  
Mohammad Matlabi ◽  
Abduljavad Khajavi ◽  
Ehsan Aliasghari ◽  
Moosa Sajjadi

<p><strong>INTRODUCTION: </strong>Medication therapy is one of the most important interventions for the control of hypertension and its complications, but patient nonadherence to prescribed antihypertensive medication is a challenge. This study was conducted to measure medication adherence and examine its determinants in patients with hypertension in a rural population of Iran.</p><p><strong>METHODS: </strong>This cross-sectional study was conducted on 422 patients with hypertension covered by the healthcare network of Bajestan, Razavi Khorasan Province, Iran. Medication adherence was measured by using the Persian version of the 8 items Morisky Medication Adherence Scale (MMAS-8). The Chi-square test and Spearman’s correlation coefficient were used to examine the relationship between the determinants of medication adherence in SPSS.</p><p><strong>RESULTS: </strong>The mean age of the patients was 65.02±8.88 years. Of the total of 422 patients, 299 (70.9%) were female. Based on the MMAS-8, medication adherence was high in 39.6% of the patients, moderate in 10.9% and low in 49.5%. The variables that correlated significantly with the level of medication adherence included age (P=0.032), education (P=0.022), income (P=0.001), the satisfaction of patients-physician communication (P=0.006), physician based education (P= 0.003), occupation, time interval of physician’s consultation (P=0.001), medication regime complexity (P=0.001), medications meals frequency (P=0.001), side effects (P=0.081) duration of the disease (P=0.015), comorbidities (P=0.001), smoking (P=0.047), patient’s ability to read medication instruction (P=0.011), the patient’s beliefs about the effectiveness of medications (P=0.001) and the patient’s beliefs about the effectiveness of health system (P=0.001). The variables of gender (P=0.147), marital status (P=0.054), and distance problems to the health center (P=0.181) were not significantly correlated with the level of medication adherence.</p><p><strong>CONCLUSION:</strong> The results of the present study revealed a low medication adherence in half of the patients with hypertension due to various personal and socioeconomic determinants as well as factors associated with the health system, therapy-related factors, disease-related factors and patient-related factors. Purposeful interventions therefore appear essential to improving medication adherence in rural populations with a focus on the effect of each determinant of medication adherence.</p>


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Carina R. Oehrn ◽  
Jana Schönenkorb ◽  
Lars Timmermann ◽  
Igor Nenadić ◽  
Immo Weber ◽  
...  

AbstractPsychosis is the most common neuropsychiatric side-effect of dopaminergic therapy in Parkinson’s disease (PD). It is still unknown which factors determine individual proneness to psychotic symptoms. Schizotypy is a multifaceted personality trait related to psychosis-proneness and dopaminergic neurotransmission in healthy subjects. We investigated whether (1) PD patients exhibit lower schizotypy than controls and (2) dopamine-related neuropsychiatric side-effects can be predicted by higher schizotypy. In this cross-sectional study, we used the Oxford-Liverpool Inventory of Feelings and Experiences in 56 PD patients (12 women, mean ± sd age: 61 ± 11 years) receiving their usual dopaminergic medication and 32 age-matched healthy controls (n = 32; 18 women, mean ± sd age: 57 ± 6 years). We further compared schizotypy scores of patients with (n = 18, 32.1%) and without previously experienced psychosis. We found that patients exhibited lower schizotypy than controls. Further, patients with a history of psychosis exhibited higher schizotypy than patients without these symptoms. Using an information theoretic measure and a machine learning approach, we show that schizotypy yields the greatest predictive value for dopamine-associated hallucinations compared to other patient characteristics and disease related factors. Our results indicate an overlap between neural networks associated with schizotypy and the pathophysiology of PD and a relationship between schizotypy and psychotic side-effects of dopaminergic medication.


Author(s):  
Martin Kampamba ◽  
Farhiyyah Abanur ◽  
Christabel Nang’andu Hikaambo ◽  
Steward Mudenda ◽  
Kennedy Saini ◽  
...  

Background: Medication adherence is the mainstay to good treatment outcomes. Failure to adhere to medication in hypertensive patients may lead to considerable deterioration of the disease resulting in increased costs of healthcare and mortality. Knowledge about the name of the drug, indications and side effects may enhance medication adherence. Therefore, the aim of this study was to assess effects of medication knowledge on medication adherence among hypertensive patients.Methods: This was a cross-sectional study that involved 120 hypertensive patients. A structured questionnaire was used to collect data on demographic characteristics. Adherence was assessed using the 8-item Morisky medication adherence scale while patient’s medication knowledge was assessed using a 7-item scale. Multiple logistic regression was used to assess factors associated with medication adherence.Results: The mean age of participants was 59 years (SD±14.9) and 10 (8.3%), 42 (35%) and 68 (56.7%) had adequate, average and poor medication knowledge respectively. The prevalence of adherence in this study was 37.5%. In multivariable logistic regression analysis, uncontrolled blood pressure (BP) (AOR: 0.38, CI: 0.16-0.90) was associated with lower likelihood of adhering to medication.Conclusions: The adherence level to treatment was low and medication knowledge of hypertensive patients was generally poor. Uncontrolled BP was associated with non-adherence. Patients with uncontrolled hypertension should be given health education and counselling regarding their condition to improve medication adherence. 


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yoshiko Tominaga ◽  
Donald E. Morisky ◽  
Mayumi Mochizuki

Abstract Background Although diabetes is one of the fastest increasing diseases in prevalence worldwide and demands significant medical resources, more than half of all patients with diabetes do not achieve the expected target level of blood glucose. As a potential cause of poor glycemic control, insufficient adherence to medication has long been discussed and variably studied. However, dropout from treatment as another plausible cause has not been fully examined. The aim of this study was to clarify profiles of patients with diabetes who discontinued pharmacotherapy (Discont group) by extracting reasons of their decisions and by comparing with those who continued (Cont group) in terms of the related factors to glycemic control. Methods A cross-sectional, internet-based survey was conducted among Japanese with diabetes registered in a database. A self-administered questionnaire consisting of the 8-item version of the Morisky Medication Adherence Scale (MMAS-8), glycosylated haemoglobin (HbA1c) level, and demographic and disease characteristics was completed by all participants. Reasons for medication discontinuation and resumption were also received retrospectively from participants in the Discont group. To examine the risk of uncontrolled HbA1c, logistic regression analysis was conducted in each group. Results In the Discont group (148 cases), older age at resumption of pharmacotherapy and current smoking habit increased the probability of uncontrolled HbA1c, whereas in the Cont group (146 cases), a familial history of diabetes and better medication adherence in MMAS-8 scores decreased the probability of uncontrolled HbA1c. A relationship between medication adherence and HbA1c level was seen in the Cont but not in the Discont group. About 70 % of those in the Discont group made their decision to terminate diabetes treatment without consulting physicians and half of them perceived their situations inappropriately. Conclusions Those who discontinued pharmacotherapy were less adherent to medication than those who did not discontinue. Risk factors for glycemic control also differed between those who discontinued and those who did not. More than one-third of participants with diabetes who discontinued pharmacotherapy had inappropriate perceptions of their disease, which medical professionals should be aware of for better interventions.


Author(s):  
Carolina Renz Pretto ◽  
Eliane Roseli Winkelmann ◽  
Leila Mariza Hildebrandt ◽  
Dulce Aparecida Barbosa ◽  
Christiane de Fátima Colet ◽  
...  

Objective: to verify the association between the health-related quality of life of chronic renal patients on hemodialysis with sociodemographic, clinical, depression and medication adherence characteristics. Method: a cross-sectional study with 183 chronic renal patients undergoing hemodialysis in the state of Rio Grande do Sul, Brazil. A sociodemographic and clinical questionnaire, Kidney Disease and Quality of Life Short-Form, Beck Depression Inventory and Morisky Medication Adherence Scale - eight items were used. Among the variables, comorbidities, complications of kidney disease and intercurrences during and after hemodialysis were evaluated. The analysis was performed with descriptive and analytical statistics. Results: 55.2% of the patients were 60 years old or older, 35.0% were hypertensive, with regular quality of life, average of 62.61. Scores below average in the dimensions of quality of life were mainly associated with repetitive infections and edema as complications of the disease, pain during hemodialysis and weakness afterwards. Low drug adherence resulted in a worse quality of life, impacting ten of the 20 dimensions evaluated and depression in all, except for patient satisfaction. Conclusion: reduced quality of life in this population is associated with depressive symptoms, complications such as repetitive infections, pain and anemia, weakness after the dialysis session and low medication adherence. Actions aimed at changing these factors can promote well-being.


2018 ◽  
Author(s):  
Jimoh-Mohammed Saka ◽  
Olabis-Mola Olaoye ◽  
Okafoagu Nneka ◽  
Aishat-Oluwatoyin Saka ◽  
Docas-Odunsi Omolola ◽  
...  

Background & Aim: Dysmenorrhea refers to the symptom of painful menstruation, which may be primary (occurring in the absence of pelvic pathology) or secondary (resulting from identifiable organic diseases). It is common gynaecological conditions that affect women of reproductive age group. The effect may be mild or severed on daily routine activities of women for one to three days of each menstrual cycle. It also has a significant effect on quality of life and personal health. This study aims to determine the burden and management of primary dysmenorrhea among the adolescent. Materials and Methods: The study was a descriptive cross-sectional study conducted among 400 randomly selected adolescent girls attending secondary schools. A semi-structured questionnaire was used to obtain data which was analysis using (SPSS) version 16.0. Data presentation was done through the use of tables and charts. Appropriate statistics test such as chi-square was used to analysis the association between the variables. The level of significance was determined at p < 0.05. Results: The mean age of respondents was 15.2 ± 0.14, and the prevalence of dysmenorrhea was found to be 287(71.8%). About 215(53.8%) had poor knowledge while others believed it to be a disease 10(2.5%), a curse from God 69 (17.2%) and 47(11.8%) do not know the meaning. Significant number 174(43.5%) of the participants exhibited negative attitude towards menstrual pain, as 122(42.5%) resorted to self-treatment and medication, only 97(33.8%) ever consulted healthcare worker. Paracetamol 54(32%) was the most used drug for self-treatment while others include Feldene 33 (19.3, Diclofenac 27(15.8) and Gelucee 25(14.6), About 103(61.7%) of subjects do not know the side effects of the drugs they used. Conclusions: The burden of primary dysmenorrhea was high, the knowledge and attitude exhibited was poor and most of the adolescent girls used a different kind of drugs whose side effects are not known. The need for in school awareness creation on the causes and it is management was emphasized. 


2017 ◽  
Vol 6 (04) ◽  
pp. 5340 ◽  
Author(s):  
Pavani Varma M.* ◽  
Prasad S.V.

Malnutrition continues to be a significant public health problem and is associated with many risk factors. To determine the association between prevalence of undernutrition, socio-demographic and maternal characteristics. It is a cross sectional study.400 children were examined for their weights and heights. Information is collected regarding the risk factors which are usually associated with undernutrition. The relevant information was recorded from each village of the mandal according to probability proportion to size. Significant association has been found with birth weight, birth interval and maternal occupation. Health education of parents regarding importance of ante-natal check-ups, proper birth spacing is essential.


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