scholarly journals Trends in Incidence and Mortality of Primary Liver Cancer in Lithuania 1998–2015

2021 ◽  
Vol 18 (3) ◽  
pp. 1191
Author(s):  
Audrius Dulskas ◽  
Povilas Kavaliauskas ◽  
Kestutis Zagminas ◽  
Ligita Jancoriene ◽  
Giedre Smailyte
Keyword(s):  
Liver Cancer ◽  
Cancer Incidence ◽  
Ductal Carcinoma ◽  
Primary Liver Cancer ◽  
Age Groups ◽  
Developed Countries ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Incidence And Mortality ◽  
Cancer Incidence Rates

Background: Recently, reports have suggested that rates of liver cancer have increased during the last decades in developed countries; increasing hepatocellular carcinoma and cholangiocarcinoma rates were reported. The aim of this study was to examine time trends in incidence and mortality rates of liver cancer for the period of 1998–2015 in Lithuania by sex, age, and histology. Methods: We examined the incidence of liver cancer from 1998 to 2015 using data from the Lithuanian Cancer Registry. Age-standardized incidence rates were calculated by sex, age, and histology. Trends were analyzed using the Joinpoint Regression Program to estimate the annual percent change. Results: A total of 3086 primary liver cancer cases were diagnosed, and 2923 patients died from liver cancer. The total number of liver cancer cases changed from 132 in 1998 to 239 in 2015. Liver cancer incidence rates changed during the study period from 5.02/100,000 in 1998 to 10.54/100,000 in 2015 in men and from 2.43/100,000 in 1998 to 6.25/100,000 in 2015 in women. Annual percentage changes (APCs) in the age-standardized rates over this period were 4.5% for incidence and 3.6% for mortality. Hepatocellular cancer incidence rates were stable from 1998 to 2005 (APC −5.9, p = 0.1) and later increased by 6.7% per year (p < 0.001). Intrahepatic ductal carcinoma incidence increased by 8.9% per year throughout the study period. The rise in incidence was observed in all age groups; however, in age groups < 50 and between 70 and 79 years, observed changes were not statistically significant. For mortality, the significant point of trend change was detected in 2001, where after stable mortality, rates started to increase by 2.4% per year. Conclusions: Primary liver cancer incidence and mortality increased in both sexes in Lithuania. The rise om incidence was observed in both sexes and main histology groups. The increasing incidence trend may be related to the prevalence of main risk factors (alcohol consumption, hepatitis B and C infections. and diabetes).

Cancer in Adolescents

1979 ◽  
Vol 1 (5) ◽  
pp. 147-152
Author(s):  
Jordan W. Finkelstein
Keyword(s):  
Health Care ◽  
Cancer Incidence ◽  
Health Care Professionals ◽  
Survival Rates ◽  
Age Groups ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Age Group ◽  
Clear Cut ◽  
Cancer Incidence Rates

Cancer is the fourth leading cause of death in the adolescent age group, preceded only by accidents, homicide, and suicide. Table 1 lists by age, sex, and race cancer incidence rates (per million) for a three-year period (1969-1971) reported by the National Cancer Institute. Table 2 lists the most commonly involved sites. There are significant differences between the younger and the older age groups. With the advent of improved treatment, survival rates have increased. Table 3 lists the survival rates for the most common forms of cancer and includes all children under 15 years of age. Although survival rates are increasing, the majority of children with cancer still die. Table 4 lists cancer mortality rates for adolescents. The issues involved in diagnosis, treatment, survival, and death present problems for all of those who care for the adolescent with cancer—the patient himself or herself, family and friends, the physician, and other health care professionals. The objectives of this article are: to increase awareness of the types of problems commonly encountered in caring for adolescents with cancer and to describe some of the ways of dealing with these problems. The problems are by no means clear-cut, and the suggested methods of dealing with them must be individualized to meet the needs of all involved.

scholarly journals White–Black Differences in Cancer Incidence, Stage at Diagnosis, and Survival Among Older Adults

2017 ◽  
Vol 30 (6) ◽  
pp. 863-881 ◽  
Author(s):  
Jessica L. Krok-Schoen ◽  
James L. Fisher ◽  
Ryan D. Baltic ◽  
Electra D. Paskett
Keyword(s):  
Older Adults ◽  
Cancer Incidence ◽  
Survival Probability ◽  
Age Groups ◽  
Relative Survival ◽  
Incidence Rates ◽  
Stage At Diagnosis ◽  
Black Adults ◽  
Incidence And Mortality ◽  
Cancer Incidence Rates

Objective: To identify potential White–Black differences in cancer incidence rates, stage at diagnosis, and relative survival probabilities among older adults using Surveillance, Epidemiology, and End Results (SEER) data. Method: Differences in cancer incidence, stage at diagnosis, and 5-year relative survival probability were examined for cases diagnosed within the most recent 5-year period and over time for cases diagnosed from 1973 to 2013 (incidence only) for older White and Black adults. Results: Among adults aged 65 to 74, 75 to 84, and 85 years and older, Black adults had higher cancer incidence rates per 100,000 than White males from 1973 to 2013, respectively. Late stage and unstaged cancers were more common among Black adults in each of the three age groups compared with Whites. Five-year relative survival probability for all invasive cancers combined was higher for Whites than Blacks in each of the three age groups. Discussion: Continued efforts are needed to reduce racial disparities in cancer incidence and mortality among older adults.

scholarly journals CANCER INCIDENCE AND MORTALITY IN CHILDREN AND ADOLESCENTS IN PRIMORSKY KRAI FOR THE 2008–2018 PERIOD

2020 ◽  
Vol 19 (6) ◽  
pp. 19-27
Author(s):  
L. M. Minkina ◽  
M. M. Tsvetkov ◽  
Ya. S. Tikhonova ◽  
M. A. Postoykina
Keyword(s):  
Children And Adolescents ◽  
Incidence Rate ◽  
Cancer Incidence ◽  
Cancer Registries ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Annual Growth Rate ◽  
Primorsky Krai ◽  
Incidence And Mortality ◽  
Cancer Incidence Rates

Background. Cancer is a leading cause of death in children and adolescents worldwide. The cancer incidence rate in children and adolescents has been on the rise for decades. Climatic, geographic and social factors of the region play an important role for cancer incidence.Objective: to analyze the cancer incidence and mortality rates in children and adolescents of Prymorsky krai.Methods. Cancer incidence rates in Russia for 2008–2018 as well as cancer incidence among children treated at the regional pediatric hematology/oncology center (Vladivostok, Russia) for 2014–2019 were analyzed.Results. No statistically significant differences in the cancer incidence rates for the 2008–2018 period between children and adolescents of Primorsky krai and the russian federation in the whole and the far-eastern federal district were found. In in Primorsky krai, there was a variability in the incidence rate during the analyzed period, a negative average annual growth rate in the group of children under 14 years of age (-0.86 %). For the 2008–2018 period, the cancer mortality rate in children and adolescents of Primorsky krai significantly decreased (from 5.65 ‰ in 2008 to 2.6 ‰ in 2018), with the average annual increase rate in children aged 017 years of -9.17 %. In 2014–2019, the quality of cancer detection improved significantly, and the number of children and adolescents with stage iiiiv cancer reduced.Conclusion. Cancer prevention and early detection can potentially reduce the cancer incidence and mortality rates in children and adolescents in Primorsky krai. Population-based cancer registries are needed for quantifying the burden of cancer in children and adolescents and assessing prevention and control programs.

scholarly journals Colorectal Cancer in Young and Older Adults in Uruguay: Changes in Recent Incidence and Mortality Trends

2021 ◽  
Vol 18 (15) ◽  
pp. 8232
Author(s):  
Carina Musetti ◽  
Mariela Garau ◽  
Rafael Alonso ◽  
Marion Piñeros ◽  
Isabelle Soerjomataram ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Older Adults ◽  
Cancer Incidence ◽  
Age Groups ◽  
Incidence Rates ◽  
Mortality Trends ◽  
Screening Programs ◽  
Lifestyle Risk Factors ◽  
Incidence And Mortality ◽  
Colorectal Cancer Incidence

Uruguay has the highest colorectal cancer incidence rates in Latin America. Previous studies reported a stable incidence and a slight increase in mortality among males. We aimed to assess colorectal cancer incidence (2002–2017) and mortality trends (1990–2017) by age groups and sex, using data from the National Cancer Registry. Annual percent changes (APCs) were estimated using joinpoint regression models. We included 27,561 colorectal cancer cases and 25,403 deaths. We found an increasing incidence among both males and females aged 40–49, with annual increases of 3.1% (95%CI: 1.21–5.03) and 2.1% (95%CI: 0.49–3.66), respectively, and an increasein the rate in older males (70+) of 0.60% (95%CI: 0.02–1.20) per year between 2002 and 2017. Mortality remained stable among those younger than 50, whereas it decreased for older females aged 50–69 and 70+ (APC: −0.61% (−1.07–0.14) and −0.68% (−1.02–0.34), respectively), and increased for the oldest males (70+; APC: 0.74 (0.47–1.01)). In conclusion, we found rising colorectal cancer incidence accompanied by stable mortality in young adults. Sex disparities were also found among the older adults, with a more favorable pattern for females. Exposures to dietary and lifestyle risk factors, and inequalities in access to and awareness of screening programs, are probably among the main underlying causes and deserve further investigation.

Diarrhoea morbidity and mortality in older children, adolescents, and adults

2010 ◽  
Vol 138 (9) ◽  
pp. 1215-1226 ◽  
Author(s):  
C. L. FISCHER WALKER ◽  
R. E. BLACK
Keyword(s):  
Eastern Mediterranean ◽  
Age Groups ◽  
Eastern Mediterranean Region ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Morbidity And Mortality ◽  
Mortality Data ◽  
Older Children ◽  
Incidence And Mortality ◽  
Adolescents And Adults

SUMMARYDiarrhoea is a leading cause of morbidity and mortality yet diarrhoea specific incidence and mortality rates for older children, adolescents, and adults have not been systematically calculated for many countries. We conducted a systematic literature review to generate regional incidence rates by age and to summarize diarrhoea specific mortality rates for regions of the world with inadequate vital registration data. Diarrhoea morbidity rates range from 29·9 episodes/100 person-years for adults in the South East Asian region to 88·4 episodes/100 person-years in older children in the Eastern Mediterranean region and have remained unchanged in the last 30 years. Diarrhoea mortality rates decline as the child ages and remain relatively constant during adulthood. These data are critical for improving estimates worldwide and further highlight the need for improved diarrhoea specific morbidity and mortality data in these age groups.

scholarly journals Environment as a Potential Key Determinant of the Continued Increase of Prostate Cancer Incidence in Martinique

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Dominique Belpomme ◽  
Philippe Irigaray
Keyword(s):  
Prostate Cancer ◽  
Life Expectancy ◽  
Cancer Incidence ◽  
Developed Countries ◽  
Incidence Rates ◽  
Prostate Cancer Incidence ◽  
Caribbean Islands ◽  
Cancer Incidence Rates ◽  
Genetic Susceptibility Factor ◽  
Insular Populations

Prostate cancer incidence is steadily increasing in many developed countries. Because insular populations present unique ethnic, geographical, and environmental characteristics, we analyzed the evolution of prostate cancer age-adjusted world standardized incidence rates in Martinique in comparison with that of metropolitan France. We also compared prostate cancer incidence rates, and lifestyle-related and socioeconomic markers such as life expectancy, dietary energy, and fat supply and consumption, with those in other Caribbean islands, France, UK, Sweden, and USA. The incidence rate of prostate cancer in Martinique is one of the highest reported worldwide; it is continuously growing since 1985 in an exponential mode, and despite a similar screening detection process and lifestyle-related behaviour, it is constantly at a higher level than in metropolitan France. However, Caribbean populations that are genetically close to that of Martinique have generally much lower incidence of prostate cancer. We found no correlation between prostate cancer incidence rates, life expectancy, and diet westernization. Since the Caribbean African descent-associated genetic susceptibility factor would have remained constant during the 1980–2005, we suggest that in Martinique some environmental change including the intensive use of carcinogenic organochlorine pesticides might have occurred as key determinant of the persisting highly growing incidence of prostate cancer.

scholarly journals LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA

2021 ◽  
Vol 20 (4) ◽  
pp. 30-38
Author(s):  
A. A. Mordovskii ◽  
A. A. Aksarin ◽  
A. M. Parsadanyan ◽  
M. D. Ter-Ovanesov ◽  
P. P. Troyan
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Mortality Rate ◽  
Cancer Incidence ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Lung Cancer Incidence ◽  
Cross Correlation Analysis ◽  
Incidence And Mortality ◽  
Khanty Mansi Autonomous

The aim of the study was to assess the lung cancer incidence and mortality in the Khanty-mansi autonomous okrug – Yugra during the period 1999–2019.Material and methods. We have studied the lung cancer incidence and mortality rates in Yugra over the last 21 years (1999–2019).Results. In Yugra, the lung cancer (lc) incidence rates increased by 24.7 % from 1999 to 2019, demonstrating higher rates than those in the Russian Federation (RF), where lc incidence rates decreased by 20.3 %. In 2019, the age-standardized incidence rate was 30.5 per 100,000 (22.7 for RF); the age-standardized mortality rate was 16.4 per 100,000 (18.4 for RF). The mortality rate from lc in Yugra was 9.6 times higher in males than in females (35.5 vs. 3.7 per 100,000). The cross-correlation analysis revealed a correlation between the lc incidence/mortality and air pollution in Yugra. The main carcinogens in Yugra were formaldehyde, phenol, nitrogen dioxide, and benzapyrene. The assessment of the relationship between the age-standardized lc incidence/mortality rates and the amount of pollutants emitted into the atmosphere revealed that their synergistic effects with tobacco smoking can double the risk of lung cancer development. The increase in the number of chest computed tomography (ct) scans performed in the context of the pandemic caused by covid-19 infection led to an 18 % increase in the number of incidentally detected pulmonary nodules, of which 9 % of cases were diagnosed as lc.Conclusion. The lc incidence rates in Yugra tended to increase. The high rate of lc incidence is caused by man-made and natural factors, which requires the implementation of a screening program with the use of low-dose computed tomography in order to improve the early detection and prevention of this disease.

A Simulation Model for Small-area Cancer Incidence Rates

2004 ◽  
Vol 43 (05) ◽  
pp. 493-498 ◽  
Author(s):  
A. Daugs ◽  
M. Meyer ◽  
M. Radespiel-Tröger
Keyword(s):  
Cancer Patient ◽  
Cancer Incidence ◽  
Small Area ◽  
Age Distribution ◽  
Incidence Rates ◽  
Cancer Registration ◽  
Mortality Data ◽  
Simulation Tool ◽  
Incidence And Mortality ◽  
Cancer Incidence Rates

Summary Objectives: Cancer epidemiologists are often asked by members of the interested public about possible associations between suspected carcinogens and apparently increased small-area cancer incidence rates. Frequently, no systematic incidence differences can be demonstrated. Nevertheless, it is necessary to address public concerns about suspected cancer clusters. To facilitate explanations about the large random variation of small-area tumor incidence, we implemented a software simulation tool in R. Methods: Under the assumption of no cancer causes other than chance, the tool simulates a small village population with an average number of five inhabitants per house and allows graphical visualisation of ten streets with 100 houses. Published age-specific incidence and mortality data are used for event sampling based on the binomial distribution. Program parameters include sample size, age distribution, cancer incidence, and mortality rates. Results: On average, 22 percent (2.2/10) of all houses per street have been inhabited by at least one cancer patient during the last five years in our simulated small village. A situation where all (10) houses in a street have been inhabited by at least one cancer patient during the last five years appears to be very rare (less than one in a million streets). Conclusions: Our software tool can be used effectively for numerical and graphical visualisation of small-area tumour incidence and prevalence rates due to chance alone. The explanation of basic epidemiological concepts to members of the public can help to increase public motivation and support for population-based cancer registration. Our simulation tool can be used to support this goal.

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