scholarly journals Zoonotic Risk of Encephalitozoon Cuniculi in Animal-Assisted Interventions: Laboratory Strategies for the Diagnosis of Infections in Humans and Animals

2021 ◽  
Vol 18 (17) ◽  
pp. 9333
Author(s):  
Antonio Santaniello ◽  
Ilaria Cimmino ◽  
Ludovico Dipineto ◽  
Ayewa Lawoe Agognon ◽  
Francesco Beguinot ◽  
...  
Keyword(s):  
Literature Review ◽  
Human Health ◽  
Respiratory Symptoms ◽  
Diagnostic Techniques ◽  
Comprehensive Analysis ◽  
Fundamental Importance ◽  
Infectious Agents ◽  
Encephalitozoon Cuniculi ◽  
Zoonotic Risk ◽  
Diagnostic Approaches

The involvement of animals for therapeutic purposes has very ancient roots. To date, it is clear that animal-assisted interventions (AAIs), in addition to ensuring the replacement of missing or deficient affects, improves psychophysiological parameters connected to human health. However, AAI could potentially present risks related to the transmission of infectious agents from animals to humans. Among these microorganisms, E. cuniculi is a microspore which induces pathological effects (fever, headache, nausea, vomiting, diarrhea, breathlessness, respiratory symptoms, and weakness) in both humans and animals. Consequently, an accurate and fast diagnosis of E. cuniculi infection, as well as the identification of new diagnostic approaches, is of fundamental importance. This literature review was carried out to provide an extensive and comprehensive analysis of the most recent diagnostic techniques to prevent and care for E. cuniculi-associated risks in the AAI field.

scholarly journals Novel Blood Biomarkers for an Earlier Diagnosis of Alzheimer’s Disease: A Literature Review

2020 ◽  
Author(s):  
Shiavax Rao ◽  
Andrew J. Boileau
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Literature Review ◽  
Clinical Diagnosis ◽  
Sensitivity And Specificity ◽  
Memory Loss ◽  
High Sensitivity ◽  
Diagnostic Techniques ◽  
Pubmed Database ◽  
Diagnostic Approaches

Alzheimer’s disease is a neurodegenerative condition associated with neurofibrillary tangles and cortical deposition of amyloid plaques. Clinical presentation of the disease involves manifestations such as memory loss, cognitive decline and dementia with some of the earliest reported deficits being episodic memory impairment and olfactory dysfunction. Current diagnostic approaches rely on autopsy characterization of gross brain pathology, or brain imaging of biomarkers late in the disease course. The aim of this literature review is to identify and compare newly emerging and novel CSF, serum and mucosal biomarkers, with the potential of making an earlier clinical diagnosis of Alzheimer’s disease. Utilizing such techniques may allow for earlier therapeutic intervention, reduction of disability and enhancement of quality of life. Literature review and analysis was performed by screening the PubMed database for relevant studies within the past 5 years. All studies showed statistically significant (P < 0.05) differences in testing between AD patients and controls. Two categories of serum biomarkers (redox-reactive antiphospholipid antibodies and microRNAs) and an olfactory mucosal marker (microRNA-206) could discriminate between early AD patients and controls with high sensitivity and specificity. In conclusion, certain studies have shown promising results with high sensitivity and specificity, high discriminative potential for Alzheimer’s disease early in its progression, and statistically significant results in larger study samples. Utilization of such diagnostic techniques should increase the efficacy of making an earlier clinical diagnosis of Alzheimer’s disease.

scholarly journals Are Nanobiosensors an Improved Solution for Diagnosis of Leishmania?

Pharmaceutics ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 491
Author(s):  
Sona Jain ◽  
Wanessa Santana ◽  
Silvio S. Dolabella ◽  
André L. S. Santos ◽  
Eliana B. Souto ◽  
...  
Keyword(s):  
Low Income ◽  
Neglected Tropical Diseases ◽  
Diagnostic Techniques ◽  
Cross Reactivity ◽  
Low Income Countries ◽  
Future Research ◽  
Immunological Tests ◽  
Diagnostic Approaches ◽  
Signal Improvement ◽  
Adequate Management

Leishmaniasis is one of the deadliest neglected tropical diseases affecting 12–15 million people worldwide, especially in middle- and low-income countries. Rapid and accurate diagnosis of the disease is important for its adequate management and treatment. Several techniques are available for the diagnosis of leishmaniasis. Among these, parasitological and immunological tests are most widely used. However, in most cases, the utilized diagnostic techniques are not good enough, showing cross-reactivity and reduced accuracy. In recent years, many new methods have been reported with potential for improved diagnosis. This review focuses on the diagnosis of Leishmania exploring the biosensors and nanotechnology-based options for their detection. New developments including the use of nanomaterials as fluorophores, fluorescence quenchers as reducing agents and as dendrimers for signal improvement and amplification, together with the use of aptamers to replace antibodies are described. Future research opportunities to overcome the current limitations on the available diagnostic approaches are also discussed.

scholarly journals Rapamycin: Drug Repurposing in SARS-CoV-2 Infection

2021 ◽  
Vol 14 (3) ◽  
pp. 217
Author(s):  
Jiri Patocka ◽  
Kamil Kuca ◽  
Patrik Oleksak ◽  
Eugenie Nepovimova ◽  
Martin Valis ◽  
...  
Keyword(s):  
Literature Review ◽  
Human Health ◽  
World Economy ◽  
Web Of Science ◽  
Drug Repurposing ◽  
Final Analysis ◽  
High Rate ◽  
Suitable Candidate ◽  
Promising Strategy ◽  
The World

Since December 2019, SARS-CoV-2 (COVID-19) has been a worldwide pandemic with enormous consequences for human health and the world economy. Remdesivir is the only drug in the world that has been approved for the treating of COVID-19. This drug, as well as vaccination, still has uncertain effectiveness. Drug repurposing could be a promising strategy how to find an appropriate molecule: rapamycin could be one of them. The authors performed a systematic literature review of available studies on the research describing rapamycin in association with COVID-19 infection. Only peer-reviewed English-written articles from the world’s acknowledged databases Web of Science, PubMed, Springer and Scopus were involved. Five articles were eventually included in the final analysis. The findings indicate that rapamycin seems to be a suitable candidate for drug repurposing. In addition, it may represent a better candidate for COVID-19 therapy than commonly tested antivirals. It is also likely that its efficiency will not be reduced by the high rate of viral RNA mutation.

Review: Etnotaksonomi dan bioekologi tumbuhan pasak bumi (Eurycoma longifolia Jack.)

2021 ◽  
Vol 11 (2) ◽  
pp. 177-178
Author(s):  
Syafitri Hidayati ◽  
Ervizal A.M. Zuhud ◽  
Ivan Khofian Adiyaksa ◽  
Primadhika Al Manar
Keyword(s):  
Literature Review ◽  
Southeast Asia ◽  
Tropical Forest ◽  
Human Health ◽  
Natural Regeneration ◽  
Literature Study ◽  
High Rainfall ◽  
Eurycoma Longifolia ◽  
Economical Benefit ◽  
Eurycoma Longifolia Jack

Eurycoma longifolia (EL) is a species that have economical benefit as medicinal ingredients for human health. This species grows in tropical forest areas with high rainfall. Research on the ecology of EL has been done a lot, but research related to ethnotaxonomic, bioecology that includes morphology, ecology, and the association of EL with other plants hasn’t been done much. This study aim to analyze the bioecology of EL plant. The method is literature study, which is looking for literature on the results of research that has been carried out related to EL. The results showed that EL has long been known by the communities of Indonesia and other countries in Southeast Asia with several local names. This plant is also associated with other plants around where it grows, one of which is kempas (Koompassia malaccensis). Based on the results of literature review, research on natural regeneration of EL hasn’t been done much. Therefore, there is a need for research related to the natural regeneration of EL. In addition, it is necessary to conduct research related to the characteristics of the place to grow for optimal cultivation of EL. Thus, the preservation of EL in the future can be maintained.

scholarly journals Patent foramen ovale-related stroke: diagnostic approaches and the possibility of endovascular prophylaxis (clinical cases and literature review)

2020 ◽  
Vol 12 (2) ◽  
pp. 72-78 ◽  
Author(s):  
A. A. Kulesh ◽  
D. V. Ognerubov ◽  
S. A. Mekhryakov ◽  
E. V. Merkulov ◽  
L. I. Syromyatnikova ◽  
...  
Keyword(s):  
Literature Review ◽  
Patent Foramen Ovale ◽  
Foramen Ovale ◽  
Diagnostic Approaches ◽  
Clinical Cases

scholarly journals Primary Adrenal Leiomyosarcoma: A Case Report and Literature Review

2008 ◽  
Vol 2 ◽  
pp. CMO.S627 ◽  
Author(s):  
M Mencoboni ◽  
M Bergaglio ◽  
M Truini ◽  
M Varaldo
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Adrenal Mass ◽  
Clinical Course ◽  
Therapeutic Strategies ◽  
Anatomic Site ◽  
Histological Features ◽  
Mesenchymal Neoplasm ◽  
Diagnostic Approaches ◽  
Final Histological Diagnosis

The case presented here illustrates a 75 year old female patient who underwent surgical resection of a right adrenal mass of uncertain nature. The final histological diagnosis was consistent with leiomyosarcoma arising from the adrenal anatomic site. Primary leiomyosarcoma of the adrenal gland is a very rare malignant mesenchymal neoplasm: to our knowledge, this is only the twelfth case reported in literature. We describe the clinical course and a brief review of clinical and histological features, biologic behaviour, diagnostic approaches and therapeutic strategies.

A Comprehensive Summary Review of Internet Advertising and Online Market Places that Provides Detailed Insights and Understanding On What Information Systems Discipline is About

2014 ◽  
Vol 5 (1) ◽  
pp. 56-72 ◽  
Author(s):  
Efosa Idemudia
Keyword(s):  
College Students ◽  
Social Media ◽  
Information System ◽  
Information Systems ◽  
Literature Review ◽  
Comprehensive Analysis ◽  
Internet Advertising ◽  
Monetary Value ◽  
Literature Reviews

To the best of our knowledge there has been no study that has published a literature review of Internet advertising, online market places, and social e-commerce in the Information System discipline journals. Publishing such articles relating to literature reviews of online market places and Internet advertising is extremely important and essential for the following reasons: (1) to provide insights and understanding to social media and online firms on strategies that can be implemented to improve Internet revenues and click-through rates, (2) provide a comprehensive analysis of some of the most influential studies in Internet advertising and social e-commerce, (3) present some of the benefits and limitations of prior studies in Internet advertising and social e-commerce, (4) encourage scholars and researchers in all disciplines to educate and enlighten college students on what Information systems consist of, and (5) present techniques to measure the effectiveness of Internet advertising and the vast monetary value of Internet advertising.

scholarly journals Spontaneous muscle hematoma in older patients with COVID-19: two case reports and literature review

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Sara Rogani ◽  
Valeria Calsolaro ◽  
Riccardo Franchi ◽  
Alessia Maria Calabrese ◽  
Chukwuma Okoye ◽  
...  
Keyword(s):  
Literature Review ◽  
Older Patients ◽  
Respiratory Symptoms ◽  
Distress Syndrome ◽  
Case Reports ◽  
Coagulation System ◽  
Blood Tests ◽  
Hemorrhagic Complications ◽  
History Of ◽  
Caucasian Female

Abstract Background In late December 2019, a cluster of pneumonia cases due to a novel betacoronavirus, SARS-CoV-2 was reported in China. The so-called COVID 19 is responsible not only for respiratory symptoms, from mild up to pneumonia and even acute respiratory distress syndrome, but also for extrapulmonary involvement. Cases presentation Here we present two cases of spontaneous muscle hematoma in patients with SARS-CoV-2 infection, both on therapeutic LMWH for atrial fibrillation: the first one was an 86-year-old Caucasian female with a history of hypertensive cardiomyopathy and the second one was an 81-year-old Caucasian male with a history of hypertension, diabetes and ischemic heart disease. Blood tests revealed a considerable drop of hemoglobin and alterations of coagulation system. In both cases, embolization of femoral artery was performed. A few other cases of bleeding manifestations are reported in literature, while a lot has been published about the hypercoagulability related to COVID-19. Conclusions Our reports and literature review highlight the need of active surveillance for possible hemorrhagic complications in patients with SARS-CoV-2 infection.

scholarly journals Identification and life cycle based allocation of building emissions based on a systematic literature review

2021 ◽  
Vol 2042 (1) ◽  
pp. 012177
Author(s):  
K Theilig ◽  
M Vollmer ◽  
W Lang
Keyword(s):  
Life Cycle ◽  
Literature Review ◽  
Human Health ◽  
Systematic Literature Review ◽  
Implementation Strategies ◽  
Building Sector ◽  
Harmful Emissions ◽  
Use Stage ◽  
Zero Emission ◽  
Negative Impacts

Abstract Even though it is scientifically well known that there are various building emissions with harmful impacts on human health and the environment, existing evaluating approaches only refer to selected emissions and life cycle phases. Especially in today’s building sector harmful emissions are mainly evaluated in the use stage and the target is to minimize rather than avoid them. However, in order to avoid subsequent negative impacts, implementation strategies have to be developed and applied during early planning phases. This research presents an overview of relevant building emissions as well as a life cycle based approach to allocate these emissions and to show possibilities of influence towards zero emission buildings.

Sign in / Sign up

Export Citation Format

Share Document