scholarly journals The Acute Effects of Aerobic Exercise on Nocturnal and Pre-Sleep Arousal in Patients with Unipolar Depression: Preplanned Secondary Analysis of a Randomized Controlled Trial

2021 ◽  
Vol 10 (17) ◽  
pp. 4028
Author(s):  
Gavin Brupbacher ◽  
Thea Zander-Schellenberg ◽  
Doris Straus ◽  
Hildburg Porschke ◽  
Denis Infanger ◽  
...  

Unipolar depression is associated with insomnia and autonomic arousal. The aim of this study was to quantify the effect of a single bout of aerobic exercise on nocturnal heart rate variability and pre-sleep arousal in patients with depression. This study was designed as a two-arm, parallel-group, randomized, outcome assessor-blinded, controlled, superiority trial. Patients with a primary diagnosis of unipolar depression aged 18–65 years were included. The intervention consisted of a single 30 min moderate-intensity aerobic exercise bout. The control group sat and read for 30 min. The primary outcome of interest was RMSSD during the sleep period assessed with polysomnography. Secondary outcomes were additional heart rate variability outcomes during the sleep and pre-sleep period as well as subjective pre-sleep arousal. A total of 92 patients were randomized to either the exercise (N = 46) or the control (N = 46) group. Intent-to-treat analysis ANCOVA of follow-up sleep period RMSSD, adjusted for baseline levels and minimization factors, did not detect a significant effect of the allocation (β = 0.12, p = 0.94). There was no evidence for significant differences between both groups in any other heart rate variability measure nor in measures of cognitive or somatic pre-sleep arousal. As this is the first trial of its kind in this population, the findings need to be confirmed in further studies. Patients with depression should be encouraged to exercise regularly in order to profit from the known benefits on sleep and depressive symptoms, which are supported by extensive literature.

1999 ◽  
Vol 7 (4) ◽  
pp. 374-383 ◽  
Author(s):  
Richard A. Boileau ◽  
Edward McAuley ◽  
Demetra Demetriou ◽  
Naveen K. Devabhaktuni ◽  
Gregory L. Dykstra ◽  
...  

A trial was conducted to examine the effect of moderate aerobic exercise training (AET) on cardiorespiratory (CR) fitness. Previously sedentary participants, age 60-75 years, were randomly assigned to either AET treatment or a control group for 6 months. The AET consisted of walking for 40 min three times/week at an intensity that elevated heart rate to 65% of maximum heart rate reserve. The control group performed a supervised stretching program for 40 min three times/week. CR fitness was assessed before and after the treatments during a grade-incremented treadmill walking test. Both absolute and relative peak V̇O2 significantly increased (p < .01) in the AET group, whereas they decreased modestly in the control group. Maximum treadmill time increased significantly (p < .01) in the AET group relative to the control group. These results indicate that CR fitness as measured by peak V̇O2 modestly improves in the elderly with a moderate-intensity, relatively long-term aerobic exercise program.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Walid Kamal Abdelbasset ◽  
Shereen H. Elsayed ◽  
Gopal Nambi ◽  
Saud M. Alrawaili ◽  
Tamer E. Elnegamy ◽  
...  

Objective. Limited studies have assessed the effect of moderate-intensity continuous aerobic exercise on hepatic fat content and visceral lipids in hepatic patients with diabesity. This study was designed to evaluate hepatic fat content and visceral lipids following moderate-intensity continuous aerobic exercise in hepatic patients with diabesity. Design. A single-blinded randomised controlled trial. Methods. Thirty-one diabetic obese patients with nonalcoholic fatty liver disease were recruited into this study. The patients were randomly classified into exercise and control groups, fifteen patients in the exercise group and sixteen patients in the control group. The exercise group received an 8-week moderate-intensity continuous aerobic exercise program with standard medical treatment, while the control group received standard medical treatment without any exercise program. Hepatic fat content and visceral lipids were assessed before and after intervention at the end of the study. Results. Baseline and clinical characteristics showed a nonsignificant difference between the two groups (p>0.05). At the end of the intervention, the aerobic exercise showed significant improvements (serum triglycerides and low-density lipoproteins (LDLs), p≤0.002, total cholesterol, p=0.004, visceral fats, p=0.016, glycated hemoglobin (HbA1C), p=0.022, high-density lipoproteins (HDLs), p=0.038, alanine transaminases (AL), p=0.044, intrahepatic triglyceride and HOMA-IR, p=0.046, and body mass index (BMI), p=0.047), while the control group showed a nonsignificant difference (p>0.05). The postintervention analysis showed significant differences in favor of the aerobic exercise group (p<0.05). Conclusions. Moderate-intensity continuous aerobic exercise reduces the hepatic fat content and visceral lipids in hepatic patients with diabesity. Recommendations should be prescribed for encouraging moderate-intensity aerobic exercise training, particularly hepatic patients with diabesity.


Background and Aim: Heart rate variability used as a non-invasive method to investigate the effect of aerobics exercise on the cardiac autonomic system. The aim of this study was the nonlinear analysis of the effect of aerobic exercise in the water on the cardiac autonomic system in academic young's males. Materials and Methods: A total of 28 young men were randomly assigned to two groups of control and aerobic exercise in water. In the pre-test period and after the training intervention, all parameters of heart rate variability were measured by examining heart rate sequences, In the pre-test period and after the training intervention, all parameters of heart rate variability were measured by examining heart rate sequences, and then the standard deviation of the recorded sequences was interpreted by using the Poincare plot method. Independent t-test and paired t-test were used to compare the differences in the research stages. Results: Regular participation in aerobic exercise in water caused a significant (45.1±9.2 vs. 34.1±12.3) and standard deviation of time intervals of heart rate sequences compared to their adjacent sequence compared to the control group (P=0.03). The longitudinal standard deviation of time intervals of heart rate sequences compared to the pre-test (P=0.04) had a significant increase (79.5±12.5 vs. 56.9±15.8 After transferring the absolute results to normal, the normal state of the standard deviation of time intervals of heart rate sequences compared to its adjacent sequence compared to the control group (P=0.03) had a significant increase (44.7±12.05 vs. 36.5±13.52). Also, the normal state of the longitudinal standard deviation of time intervals of heart rate sequences compared to the pre-test (P=0.02) increased significantly (76.4±15.29 vs. 61.3±9.32). Conclusion: Performing aerobic exercise in an aqueous environment can be used as a useful training method to improve the responsiveness of the cardiac autonomic system.


Author(s):  
Laura Zlibinaite ◽  
Albertas Skurvydas ◽  
Sandra Kilikeviciene ◽  
Rima Solianik

Background: The effect of globally recommended levels of physical activity on cognition and motor behavior is not completely understood. Therefore, the main aim of this study was to assess the effect of 300 minutes per week of moderate-intensity aerobic exercise on cognitive and motor performance among overweight and obese working-age women. Methods: Overweight and obese participants aged 38–56 years were randomized to either a control or an experimental group performing aerobic exercise at 50% to 60% of the peak oxygen consumption for a 2-month period. Changes in aerobic fitness, cardiac autonomic function, brain-derived neurotropic factor levels, and cognitive and motor performance were assessed. Results: Although aerobic exercise reduced body weight (P < .05) and improved peak oxygen consumption (P < .05), the brain-derived neurotropic factor levels and cognitive and motor performance remained unchanged. Heart rate and blood pressure decreased (P < .05), whereas heart rate variability indices were not affected. No significant correlations between changes in heart rate variability indices and cognition were observed. Conclusions: Two months of moderate-intensity aerobic exercise decreased sympathetic activity and improved cardiovascular fitness but had no impact on cognition or motor control among these middle-aged, overweight, and obese women.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Chien-Lin Yu ◽  
Shu-Shih Hsieh ◽  
Ting-Yu Chueh ◽  
Chung-Ju Huang ◽  
Charles H. Hillman ◽  
...  

AbstractThe current study examined the effects of acute moderate-intensity aerobic exercise (MAE) on inhibitory control and resting-state heart rate variability (HRV) in children with Attention-Deficit/Hyperactivity Disorder (ADHD). Our data show that acute MAE resulted in higher response accuracy of a modified flanker task regardless of task difficulty for 60 min (p = .001). Aerobic exercise further resulted in more effective conflict detection, as measured by greater amplitude (p = .012) and shorter latency (p = .029) of the N2 component of event-related brain potential, for 60 min regardless of task difficulty. In contrast, acute MAE did not modulate sympathovagal balance signified by HRV at either 30 min or 60 min following exercise cessation. Collectively, our findings suggest that the beneficial effects of acute aerobic exercise on inhibitory control are sustained for 60 min in children with ADHD. However, acute aerobic exercise may not modulate sympathovagal balance during the post-exercise recovery. Overall, we highlight the importance of acute aerobic exercise for children with ADHD as a potential means to facilitate brain health.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Maria Meier ◽  
Eva Unternaehrer ◽  
Stephanie J. Dimitroff ◽  
Annika B. E. Benz ◽  
Ulrike U. Bentele ◽  
...  

Abstract Health and disease are strongly linked to psychophysiological states. While stress research strongly benefits from standardized stressors, no established protocol focuses on the induction of psychophysiological relaxation. To maintain health, functioning regenerative systems are however likely as important as functioning stress systems. Thus, the identification of validated relaxation paradigms is needed. Here, we investigated whether standardized massages are capable of reliably inducing physiological and psychological states of relaxation. Relaxation was indicated by changes in high frequency heart rate variability (HF-HRV), a vagally-mediated heart rate variability component, and repeated ratings of subjective relaxation, and stress levels. Sixty healthy women were randomly assigned to a vagus nerve massage (n = 19), a soft shoulder massage (n = 22), or a resting control group (n = 19). During the intervention, HF-HRV and subjective relaxation increased, while subjective stress decreased significantly in all groups. Both massage interventions elicited significantly higher HF-HRV compared to the control group. Accordingly, both massage protocols increased psychophysiological relaxation, and may serve as useful tools in future research. However, future work will have to determine which of several protocols might be used as a gold standard to induce a psychophysiological state of relaxation in the laboratory.


2002 ◽  
Vol 27 (1) ◽  
pp. 1-18 ◽  
Author(s):  
Paula R. Myslivecek ◽  
C. Ann Brown ◽  
Larry A. Wolfe

The purpose of this study was to determine whether moderate exercise training affects heart rate variability (HRV) and spontaneous baroreflex (SBR) function in healthy middle-aged women. Thirty-two sedentary women aged 40-59 yr were divided into four groups depending on reproductive state (premenopausal, PrM or postmenopausal, PoM, and training group (exercise or sedentary control group). The electrocardiographic R-R interval and systolic blood pressure (finger plethysmograph) were measured at rest during paced breathing at 16 breaths/min in the left lateral decubitus, sitting, and free standing postures, and during upright cycling at 40% maximal heart rate reserve (MHRR). After initial testing, the exercise groups underwent a 12 week walking program. After training, both exercise groups (PrM and PoM) had a longer R-R interval in all conditions, a higher SBR slope in the sitting and standing posture and lower sympathetic modulation in the standing posture, than the control groups and pre-training levels. During exercise, vagal modulation was higher and sympathetic modulation was lower in both exercise groups compared to pretraining values. Vagal modulation is increased following moderate intensity aerobic conditioning in middle-aged women. Key words: heart rate variability, spontaneous baroreflex function, exercise


2003 ◽  
Vol 28 (3) ◽  
pp. 446-461 ◽  
Author(s):  
Anthony S. Leicht ◽  
Graham D. Allen ◽  
Andrew J. Hoey

The purpose of this study was to examine the influence of age and moderate-intensity exercise training on heart rate variability (HRV), and to elucidate further the mechanism of training-induced bradycardia and cardioprotection. Electrocardiograms were recorded from 12 young (18-24 yrs) and 12 mature (29-43 yrs) individuals during supine rest and submaximal moderate exercise. Recordings were obtained prior to, midway, and following 16 weeks of aerobic exercise training designed to improve cardiorespiratory fitness and health. Training resulted in augmented estimated [Formula: see text] and bradycardia during rest and submaximal exercise. Total and low frequency components of HRV during exercise were significantly increased for the mature subjects following training whereas other measures of HRV were not significantly changed for either group. It was concluded that training of moderate intensity was insufficient to induce changes in the autonomic control of heart rate for young to mature subjects. The lack of significant HRV changes may suggest the existence of a vagal critical point, below which training-induced increases in vagal modulation may be forthcoming, and above which changes in vagal modulation may be negligible. Training-induced bradycardia and the cardioprotective effect of regular aerobic exercise may result from factors other than an increased vagal modulation. Key words: physical activity, ageing, autonomic nervous system, bradycardia, spectral analysis


1994 ◽  
Vol 2 (4) ◽  
pp. 293-303 ◽  
Author(s):  
Robert A. Swoap ◽  
Nancy Norvell ◽  
James E. Graves ◽  
Michael L. Pollock

This study examined the psychological and physiological effects of a 26-week aerobic exercise program on a sample of sedentary older men (n= 26) and women (n= 23). Subjects were randomly assigned to either a high intensity exercise group (80−85% of maximal heart rate reserve), a moderate intensity exercise group (65−70% of maximal heart rate reserve), or a no-exercise control group. Results indicated that subjects in the high intensity exercise group exhibited significant increases in aerobic capacity compared to the moderate intensity group. Both exercising groups improved aerobic capacity and had significant decreases in body weight compared to the control group. Exercising subjects also reported significantly fewer symptoms of depression at the end of the program, but not fewer than the control group. Overall, increases in VO2max were associated with decreases in depression.


2021 ◽  
pp. 026921552110007
Author(s):  
Hsin-Yi Huang ◽  
Kuo-Sheng Hung ◽  
Mei-Ling Yeh ◽  
Hsiu-Ling Chou ◽  
Albert Lou Yeh ◽  
...  

Objective: To evaluate the effect of a 12-week breathing-based leg exercises program on quality of life under stabilizing heart rate variability and reducing fatigue in regular hemodialysis patients. Design: Randomized controlled trial. Setting: A 94-bed hemodialysis department at a medical center in northern Taiwan. Participants: Eighty-six patients with end-stage renal disease undergoing hemodialysis were recruited and randomly assigned to the ExBr or control groups. Interventions: The breathing-based leg exercises program comprised abdominal breathing and low-intensity leg exercise, including leg lifts, quadriceps femoris contraction and knee flexion, and lasted for 15 minutes at one time, three times a week for 12 weeks. Main measure: Data was collected by using the World Health Organization quality of life assessment-brief, physiological signal recorder for heart rate variability and hemodialysis-related fatigue scale at baseline and on Week 4, Week 8, and Week 12. Results: Average (standard deviation) age was 53.70 (10.04) years in the ExBr group and 61.19 (10.19) years in the control group. The linear mixed model with adjusted age, creatinine, heart rate variability and fatigue revealed that the ExBr group had significantly higher quality of life than did the control group ( P = 0.01), especially on Week 12 ( P = 0.04). Fatigue was significantly correlated with quality of life ( P < 0.001). Conclusion: This study supported the benefits of the continued breathing-based leg exercises during hemodialysis for at least 12 weeks, which improved the quality of life of patients with end-stage renal disease and did not affect the stability of their vital signs.


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