High versus Moderate Intensity Aerobic Exercise in Older Adults: Psychological and Physiological Effects

1994 ◽  
Vol 2 (4) ◽  
pp. 293-303 ◽  
Author(s):  
Robert A. Swoap ◽  
Nancy Norvell ◽  
James E. Graves ◽  
Michael L. Pollock

This study examined the psychological and physiological effects of a 26-week aerobic exercise program on a sample of sedentary older men (n= 26) and women (n= 23). Subjects were randomly assigned to either a high intensity exercise group (80−85% of maximal heart rate reserve), a moderate intensity exercise group (65−70% of maximal heart rate reserve), or a no-exercise control group. Results indicated that subjects in the high intensity exercise group exhibited significant increases in aerobic capacity compared to the moderate intensity group. Both exercising groups improved aerobic capacity and had significant decreases in body weight compared to the control group. Exercising subjects also reported significantly fewer symptoms of depression at the end of the program, but not fewer than the control group. Overall, increases in VO2max were associated with decreases in depression.

2020 ◽  
Vol 24 (3) ◽  
Author(s):  
Keyvan Hejazi ◽  
Seyyed Reza Attarzadeh Hosseini ◽  
Mehrdad Fathi ◽  
Mohammad Mosaferi Ziaaldini

Background: The lack of physical activity and obesity causes mild chronic inflammation that is associated with increased plasma levels of inflammatory markers. Evidence suggests that physical activity can reduce inflammatory markers. Objectives: The purpose of this study was to determine the effects of eight weeks of aerobic training with two intensities on levels of tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and insulin resistance in obese Wistar rats. Methods: Twenty-four Wistar male rats (fourteen weeks old and weighing 250 - 300 g, body mass index > 30 g/cm2) were used. After two weeks of familiarity with the laboratory environment, the animals were randomly divided into three groups: (1) high-intensity aerobic exercise (n = 8); (2) moderate-intensity aerobic exercise (n = 8), and control (n = 8). The rats in moderate and high-intensity aerobic exercise groups were performed an increasing training for eight weeks and five days a week and one session per day for 60 minutes running at different speeds on a rodent motor-driven treadmill. Data were analyzed by paired sample t-test and repeated measures (ANOVA) for the inter-group and intra-group comparison of the variance changes. Results: Significant differences were found in serum TNF-α levels (P = 0.027 and F = 3.42), IL-6 levels (P = 0.043 and F = 2.99), and insulin resistance index (P = 0.008 and F = 4.69) between the moderate, high-intensity aerobic exercises, and control groups. The levels of TNF-α concentration was significantly different between moderate-intensity and control group (P = 0.01) and between the high-intensity and control groups (P = 0.01). The insulin resistance index in MI (P = 0.01) and HI (P = 0.01) groups significantly decreased compared to the control group. Conclusions: The results of the present study show that both types of moderate-intensity and high-intensity aerobic exercise lead to the reduction of TNF-α, interleukin-6, and insulin resistance index compared to the control group. Further studies are needed to shed light on the effects of different types of exercise on such indices, especially the use of long-term training sessions.


1999 ◽  
Vol 7 (4) ◽  
pp. 374-383 ◽  
Author(s):  
Richard A. Boileau ◽  
Edward McAuley ◽  
Demetra Demetriou ◽  
Naveen K. Devabhaktuni ◽  
Gregory L. Dykstra ◽  
...  

A trial was conducted to examine the effect of moderate aerobic exercise training (AET) on cardiorespiratory (CR) fitness. Previously sedentary participants, age 60-75 years, were randomly assigned to either AET treatment or a control group for 6 months. The AET consisted of walking for 40 min three times/week at an intensity that elevated heart rate to 65% of maximum heart rate reserve. The control group performed a supervised stretching program for 40 min three times/week. CR fitness was assessed before and after the treatments during a grade-incremented treadmill walking test. Both absolute and relative peak V̇O2 significantly increased (p < .01) in the AET group, whereas they decreased modestly in the control group. Maximum treadmill time increased significantly (p < .01) in the AET group relative to the control group. These results indicate that CR fitness as measured by peak V̇O2 modestly improves in the elderly with a moderate-intensity, relatively long-term aerobic exercise program.


2018 ◽  
Vol 1 (5) ◽  
Author(s):  
Yuli Zhang ◽  
Songtao Wang ◽  
Fei Liang ◽  
Xiangyu Shuai ◽  
Weibao Liang ◽  
...  

Objective The aim of this study was to investigate the effect of 8-week moderate-intensity and high-intensity accumulated exercise on insulin resistance in mice, compared with the moderate intensity continuous exercise with equal workload, which will provide an experimental reference for seeking a more reasonable and effective exercise program to break sedentary behavior and improve metabolic diseases such as IR. Methods Eighty 4-week-old C57BL/6J mice were randomly divided into normal diet group (group C) and high-fat diet group (group H), fed with different diet. At the 10th weekend, insulin resistance model was judged by OGTT curve (AUC) and fasting blood glucose. All mice with insulin resistance were randomly divided into four groups: IR control group (IC), IR moderate-intensity continuous exercise group (IE), IR moderate-intensity accumulated exercise group (IM), IR high-intensity accumulated exercise group (IH), retained normal diet control group (C), with 12 mice for each group. All groups were fed with normal feed. The three exercise-related group performed an 8-week’s treadmill exercise program with equal workload (involve preparation and relaxation activities,0°platform slope, 5 days/week). For IE group, mice run 50min continuously with the velocity of 11m/min. For IM group,mice exercised 12.5 min per session, total 4 sessions per day, with 3-hour’s interval and the velocity of 11m/min. The IH group performed an alike exercise program with IM group, except the running speed (19m/min) and exercise time (7.5min). On the 8th weekend of exercise, FBG, OCTT, FINS, HOME- IR, and ISI were tested for each groups. Results 1. Compared with group C, body weight, FBG and OGTT-AUC were significantly increased in group H (P<0.05 or P<0.01). 76% mice were induced to insulin resistance successfully.  2. Before and after exercise intervention of 8 weeks, there were no significant changes in body weight and OGTT-AUC, while the FBG was significantly increased in IC group (P<0.05). Body weight, FBG, and OGTT-AUC significantly decreased in IE group, IM group and IH group (P<0.05 or P<0.01). 3. After 8 weeks of exercise intervention, the FBG in the IE group, IM group, and IH group were significantly lower than that in C group (P<0.05 or P<0.01). Compared with the IC group, the FBG, FINS, OGTT-AUC, and HOME-IR in IM group, IH group and IE group were lower than those in the IC group (P<0.05 or P<0.01). Compared with the IE group, the body weight and HOME-IR index of IH group were significantly lower than those in IE group (P<0.01). Compared with IH group, the HOME-IR in IH group was lower than that in IM group (P<0.05); There was no significant difference between IM group and IE group. Conclusions 1. Chronic moderate-intensity continuous exercise, moderate-intensity accumulated exercise, and high-intensity accumulated exercise all can effectively improve the glucose metabolism and insulin resistance in IR mice. 2.Compared with moderate-intensity accumulated exercise and moderate-intensity continuous exercise, the high-intensity accumulated exercise with equal workload is more effective in reducing the body weight and improving insulin resistance in IR mice.  


Medicina ◽  
2019 ◽  
Vol 55 (4) ◽  
pp. 105 ◽  
Author(s):  
Iman Khakroo Abkenar ◽  
Farhad Rahmani-nia ◽  
Giovanni Lombardi

Background and Objectives: The results of the studies show that the intensity and volume of aerobic exercise activity produce different responses of the immune system. This study aims to show how the signaling pathway of the inflammatory NLRP3 complex is influenced by the acute and chronic effects of moderate and high-intensity aerobic exercises in young men. Materials and Methods: Accordingly, 60 healthy (BMI = 23.56 ± 2.67) young (24.4 ± 0.4) students volunteered to participate in the study that was randomly divided into two experimental (n = 20) groups and one control (n = 20) group. The training protocol started with two intensity levels of 50% for a moderate group and 70% of maximum heart rate for high group for 30 min and then continued until reaching 70% (moderate group) and 90% (high group) of the maximum heart rate, respectively. Using Real Time-PCR method, the expression of NLRP3 gene and ELISA- were measured by IL-1β, IL-18. Results: The results showed that acute aerobic exercise with moderate intensity had no significant effect on the expression of NLRP3 gene and serum levels of IL-1β and IL-18 cytokines (p > 0.05) when acute exercise, with high intensity, begins an initiation of the activity of the inflammatory complex with elevated serum levels of IL-1β, IL-18, and NLRP3 gene expression (p < 0.05). In addition, chronic exercise with moderate intensity significantly reduced the expression of NLRP3 gene and serum levels of IL-1β, IL-18 cytokines (p < 0.05). In the case of chronic exercise with high intensity, a significant increase in expression of gene, NLRP3 and serum levels of IL-1β, IL-18 cytokines were observed (p < 0.05). Conclusions: Generally, it can be concluded that chronic exercise with moderate intensity is effective in decreasing the expression of the inflammasome and inflammation.


1997 ◽  
Vol 83 (1) ◽  
pp. 160-165 ◽  
Author(s):  
Margaret D. Fitzgerald ◽  
Hirofumi Tanaka ◽  
Zung V. Tran ◽  
Douglas R. Seals

Fitzgerald, Margaret D., Hirofumi Tanaka, Zung V. Tran, and Douglas R. Seals. Age-related declines in maximal aerobic capacity in regularly exercising vs. sedentary women: a meta-analysis. J. Appl. Physiol. 83(1): 160–165, 1997.—Our purpose was to determine the relationship between habitual aerobic exercise status and the rate of decline in maximal aerobic capacity across the adult age range in women. A meta-analytic approach was used in which mean maximal oxygen consumption (V˙o 2 max) values from female subject groups (ages 18–89 yr) were obtained from the published literature. A total of 239 subject groups from 109 studies involving 4,884 subjects met the inclusion criteria and were arbitrarily separated into sedentary (groups = 107; subjects = 2,256), active (groups = 69; subjects = 1,717), and endurance-trained (groups = 63; subjects = 911) populations.V˙o 2 max averaged 29.7 ± 7.8, 38.7 ± 9.2, and 52.0 ± 10.5 ml ⋅ kg−1 ⋅ min−1, respectively, and was inversely related to age within each population ( r = −0.82 to −0.87, all P < 0.0001). The rate of decline inV˙o 2 max with increasing subject group age was lowest in sedentary women (−3.5 ml ⋅ kg−1 ⋅ min−1⋅ decade−1), greater in active women (−4.4 ml ⋅ kg−1 ⋅ min−1⋅ decade−1), and greatest in endurance-trained women (−6.2 ml ⋅ kg−1 ⋅ min−1 ⋅ decade−1) (all P < 0.001 vs. each other). When expressed as percent decrease from mean levels at age ∼25 yr, the rates of decline inV˙o 2 max were similar in the three populations (−10.0 to −10.9%/decade). There was no obvious relationship between aerobic exercise status and the rate of decline in maximal heart rate with age. The results of this cross-sectional study support the hypothesis that, in contrast to the prevailing view, the rate of decline in maximal aerobic capacity with age is greater, not smaller, in endurance-trained vs. sedentary women. The greater rate of decline inV˙o 2 max in endurance-trained populations may be related to their higher values as young adults (baseline effect) and/or to greater age-related reductions in exercise volume; however, it does not appear to be related to a greater rate of decline in maximal heart rate with age.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Walid Kamal Abdelbasset ◽  
Shereen H. Elsayed ◽  
Gopal Nambi ◽  
Saud M. Alrawaili ◽  
Tamer E. Elnegamy ◽  
...  

Objective. Limited studies have assessed the effect of moderate-intensity continuous aerobic exercise on hepatic fat content and visceral lipids in hepatic patients with diabesity. This study was designed to evaluate hepatic fat content and visceral lipids following moderate-intensity continuous aerobic exercise in hepatic patients with diabesity. Design. A single-blinded randomised controlled trial. Methods. Thirty-one diabetic obese patients with nonalcoholic fatty liver disease were recruited into this study. The patients were randomly classified into exercise and control groups, fifteen patients in the exercise group and sixteen patients in the control group. The exercise group received an 8-week moderate-intensity continuous aerobic exercise program with standard medical treatment, while the control group received standard medical treatment without any exercise program. Hepatic fat content and visceral lipids were assessed before and after intervention at the end of the study. Results. Baseline and clinical characteristics showed a nonsignificant difference between the two groups (p>0.05). At the end of the intervention, the aerobic exercise showed significant improvements (serum triglycerides and low-density lipoproteins (LDLs), p≤0.002, total cholesterol, p=0.004, visceral fats, p=0.016, glycated hemoglobin (HbA1C), p=0.022, high-density lipoproteins (HDLs), p=0.038, alanine transaminases (AL), p=0.044, intrahepatic triglyceride and HOMA-IR, p=0.046, and body mass index (BMI), p=0.047), while the control group showed a nonsignificant difference (p>0.05). The postintervention analysis showed significant differences in favor of the aerobic exercise group (p<0.05). Conclusions. Moderate-intensity continuous aerobic exercise reduces the hepatic fat content and visceral lipids in hepatic patients with diabesity. Recommendations should be prescribed for encouraging moderate-intensity aerobic exercise training, particularly hepatic patients with diabesity.


2015 ◽  
Vol 21 (1) ◽  
pp. 54-60 ◽  
Author(s):  
Luciano Antonacci Condessa ◽  
Christian Emmanuel Torres Cabido ◽  
André Maia Lima ◽  
Daniel Barbosa Coelho ◽  
Vinicius M. Rodrigues ◽  
...  

This study compared the exercise intensity of four specific soccer training sessions (friendly and training match, tactical and technical workouts). Ten professional soccer players (24.2 ± 3.7 years, 177.9 ± 7.3 cm, 63.2 ± 4.6 mLO2•kg-1•min-l) were recruited. A treadmill progressive interval test was performed to determine the players' VO2max, maximal heart rate (HRmax), HR-VO2 curve, and the heart rate corresponding to blood lactate concentrations of 2 and 4 mmol/L. The heart rate during the training sessions was used to estimate the exercise intensity and to classify them into intensity zones (low-intensity: <2 mmol/L; moderate-intensity: between 2 and 4 mmol/L; high-intensity: >4 mmol/L). Exercise intensities were different among training sessions (friendly match: 86.0 ± 5.1% HRmax; training match: 81.2 ± 4.1% HRmax; tactical workout: 70.4 ± 5.3% HRmax; technical workout: 62.1 ± 3.6% HRmax). The friendly match presented the highest percentage of time performed in the high-intensity zone.


2008 ◽  
Vol 115 (9) ◽  
pp. 283-293 ◽  
Author(s):  
Inga E. Schjerve ◽  
Gjertrud A. Tyldum ◽  
Arnt E. Tjønna ◽  
Tomas Stølen ◽  
Jan P. Loennechen ◽  
...  

Regular exercise training is recognized as a powerful tool to improve work capacity, endothelial function and the cardiovascular risk profile in obesity, but it is unknown which of high-intensity aerobic exercise, moderate-intensity aerobic exercise or strength training is the optimal mode of exercise. In the present study, a total of 40 subjects were randomized to high-intensity interval aerobic training, continuous moderate-intensity aerobic training or maximal strength training programmes for 12 weeks, three times/week. The high-intensity group performed aerobic interval walking/running at 85–95% of maximal heart rate, whereas the moderate-intensity group exercised continuously at 60–70% of maximal heart rate; protocols were isocaloric. The strength training group performed ‘high-intensity’ leg press, abdominal and back strength training. Maximal oxygen uptake and endothelial function improved in all groups; the greatest improvement was observed after high-intensity training, and an equal improvement was observed after moderate-intensity aerobic training and strength training. High-intensity aerobic training and strength training were associated with increased PGC-1α (peroxisome-proliferator-activated receptor γ co-activator 1α) levels and improved Ca2+ transport in the skeletal muscle, whereas only strength training improved antioxidant status. Both strength training and moderate-intensity aerobic training decreased oxidized LDL (low-density lipoprotein) levels. Only aerobic training decreased body weight and diastolic blood pressure. In conclusion, high-intensity aerobic interval training was better than moderate-intensity aerobic training in improving aerobic work capacity and endothelial function. An important contribution towards improved aerobic work capacity, endothelial function and cardiovascular health originates from strength training, which may serve as a substitute when whole-body aerobic exercise is contra-indicated or difficult to perform.


2021 ◽  
Vol 12 ◽  
Author(s):  
Yuning Hou ◽  
Renyan Ma ◽  
Song Gao ◽  
Keneilwe Kenny Kaudimba ◽  
Hongmei Yan ◽  
...  

BackgroundHyperuricemia (HUA) is a metabolic disease by purine metabolism disorders. It is a risk factor for many chronic diseases, including diabetes, hypertension, and heart disease. Studies have shown that exercise can effectively reduce serum uric acid (SUA), but the optimal exercise dose, intensity, and mode of exercise for improving HUA have not been verified in clinical studies. Therefore, this study aims to explore the effect of different exercise intensities in improving SUA of patients with HUA.Methods and AnalysisA randomized, single-blind, parallel controlled trial will be conducted in this study. 186 HUA patients who meet the inclusion criteria will be randomly divided into a 1:1:1 ratio (1): control group (2), low-intensity exercise group (brisk walking, 57-63% maximum heart rate, 150 min/week, 12 months), and (3) moderate-intensity exercise group (jogging, 64-76% maximum heart rate, 150 min/week, 12 months). The three groups of subjects will receive the same health education and prohibition of high-purine diet during the intervention period. The primary outcomes will be SUA concentration, SUA concentration change (mg/dL), SUA change rate (%), and the proportion of HUA patients. Secondary outcomes will include anthropometric parameters (body weight, waist circumference, hip circumference, BMI); physiological indicators (blood pressure, grip, vital capacity, maximum oxygen); biochemical indicators (blood lipid, blood sugar, liver enzyme, creatinine, and blood urea nitrogen). Each group of patients will go through an assessment at baseline, 3rd, 6th, and 12th months.DiscussionThis study will evaluate the effect of 12-month low-intensity exercise and moderate-intensity exercise on HUA patients. We hypothesize that both low-intensity and moderate-intensity exercise would improve HUA as compared with no-exercise control, and that moderate-intensity exercise would be more effective than low-intensity exercise in improving HUA. These results can provide a basis for the current physical activity guidelines for HUA’s healthy lifestyle management.Ethics and DisseminationThis study has been approved by the Ethical Review Committee of the Shanghai University of Sport (approval number: 102772020RT005). Informed consent will be obtained from all participants or their guardians. The authors intend to submit the study findings to peer-reviewed journals or academic conferences to be published.Clinical Trial RegistrationChinese Clinical Trial Registry, identifier ChiCTR2100042643.


2021 ◽  
Author(s):  
Yusaku Amaya ◽  
Tetsuya Abe ◽  
Kenji Kanbara ◽  
Hisaharu Shizuma ◽  
Yasushi Akiyama ◽  
...  

Abstract Background:Long-term aerobic exercise is a key intervention for improving cognitive function as well as enhancing musculoskeletal and cardiorespiratory system functions. Additionally, decision-making, in which cognitive function is involved, can be an important factor for initiating and maintaining exercise. According to Damasio’s somatic marker hypothesis, somatic experience plays a fundamental role in decision-making. Interoception is a sense of physiological information related to emotions and is known to influence cognitive function. Here, we investigated changes in interoception during moderate-intensity aerobic exercise at a level that could improve cognitive function.Methods:Healthy university students were divided into an exercise group (n = 37) and a control group (n = 11). The exercise group performed bench step exercises at an intensity of 50% heart rate reserve for 30 minutes a day, three times a week, for three months. Cognitive function was assessed by measuring auditory information/working memory processing speed with a Paced Auditory Serial Addition Task (PASAT), and interoceptive accuracy (IA) was measured with a heartbeat tracking task.Results:There was a significant positive correlation between IA and PASAT scores at pre-intervention. But exercise did not lead to a significant increase in PASAT scores in comparison with the control group. IA scores were improved at 2- and 3-month post-intervention only in the exercise group.Conclusions:This suggested that interoception may be associated with the improvement in cognitive function produced by long-term aerobic exercise. Further investigation is warranted to clarify the causal relationship between interoception and cognitive function during exercise interventions.Trial registration: UMIN, UMIN000042891. 04/01/2021, retrospectively registered.


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