scholarly journals The Impact and Burden of Neurological Sequelae Following Bacterial Meningitis: A Narrative Review

2021 ◽  
Vol 9 (5) ◽  
pp. 900 ◽  
Author(s):  
Nicoline Schiess ◽  
Nora E. Groce ◽  
Tarun Dua
Keyword(s):  
Bacterial Meningitis ◽  
Vision Loss ◽  
Middle Income ◽  
Neurological Sequelae ◽  
Middle Income Countries ◽  
Resource Limited ◽  
Behaviour Changes ◽  
Outcome Knowledge ◽  
The Impact

The burden, impact, and social and economic costs of neurological sequelae following meningitis can be devastating to patients, families and communities. An acute inflammation of the brain and spinal cord, meningitis results in high mortality rates, with over 2.5 million new cases of bacterial meningitis and over 236,000 deaths worldwide in 2019 alone. Up to 30% of survivors have some type of neurological or neuro-behavioural sequelae. These include seizures, hearing and vision loss, cognitive impairment, neuromotor disability and memory or behaviour changes. Few studies have documented the long-term (greater than five years) consequences or have parsed out whether the age at time of meningitis contributes to poor outcome. Knowledge of the socioeconomic impact and demand for medical follow-up services among these patients and their caregivers is also lacking, especially in low- and middle-income countries (LMICs). Within resource-limited settings, the costs incurred by patients and their families can be very high. This review summarises the available evidence to better understand the impact and burden of the neurological sequelae and disabling consequences of bacterial meningitis, with particular focus on identifying existing gaps in LMICs.

scholarly journals Impact of national interventions to promote responsible antibiotic use: a systematic review

2019 ◽  
Vol 75 (1) ◽  
pp. 14-29 ◽  
Author(s):  
Jane Mingjie Lim ◽  
Shweta Rajkumar Singh ◽  
Minh Cam Duong ◽  
Helena Legido-Quigley ◽  
Li Yang Hsu ◽  
...  
Keyword(s):  
Systematic Review ◽  
National Level ◽  
Public Health Problem ◽  
Antibiotic Use ◽  
Antibiotic Consumption ◽  
Middle Income ◽  
Middle Income Countries ◽  
Policy Interventions ◽  
The Impact

Abstract Background Global recognition of antimicrobial resistance (AMR) as an urgent public health problem has galvanized national and international efforts. Chief among these are interventions to curb the overuse and misuse of antibiotics. However, the impact of these initiatives is not fully understood, making it difficult to assess the expected effectiveness and sustainability of further policy interventions. We conducted a systematic review to summarize existing evidence for the impact of nationally enforced interventions to reduce inappropriate antibiotic use in humans. Methods We searched seven databases and examined reference lists of retrieved articles. To be included, articles had to evaluate the impact of national responsible use initiatives. We excluded studies that only described policy implementations. Results We identified 34 articles detailing interventions in 21 high- and upper-middle-income countries. Interventions addressing inappropriate antibiotic access included antibiotic committees, clinical guidelines and prescribing restrictions. There was consistent evidence that these were effective at reducing antibiotic consumption and prescription. Interventions targeting inappropriate antibiotic demand consisted of education campaigns for healthcare professionals and the general public. Evidence for this was mixed, with several studies showing no impact on overall antibiotic consumption. Conclusions National-level interventions to reduce inappropriate access to antibiotics can be effective. However, evidence is limited to high- and upper-middle-income countries, and more evidence is needed on the long-term sustained impact of interventions. There should also be a simultaneous push towards standardized outcome measures to enable comparisons of interventions in different settings.

Immunological footprint: the development of a child's immune system in environments rich in microorganisms and parasites

Parasitology ◽  
2011 ◽  
Vol 138 (12) ◽  
pp. 1508-1518 ◽  
Author(s):  
YENNY DJUARDI ◽  
LINDA J. WAMMES ◽  
TANIAWATI SUPALI ◽  
ERLIYANI SARTONO ◽  
MARIA YAZDANBAKHSH
Keyword(s):  
Immune System ◽  
Environmental Factors ◽  
Later Life ◽  
Third Party ◽  
Middle Income ◽  
Middle Income Countries ◽  
Geographical Regions ◽  
Micro Organisms ◽  
The Impact

SUMMARYThe shaping of a child's immune system starts in utero, with possible long-term consequences in later life. This review highlights the studies conducted on the development of the immune system in early childhood up to school-age, discussing the impact that environmental factors may have. Emphasis has been put on studies conducted in geographical regions where exposure to micro-organisms and parasites are particularly high, and the effect that maternal exposures to these may have on an infant's immune responses to third-party antigens. In this respect we discuss the effect on responses to vaccines, co-infections and on the development of allergic disorders. In addition, studies of the impact that such environmental factors may have on slightly older (school) children are highlighted emphasizing the need for large studies in low to middle income countries, that are sufficiently powered and have longitudinal follow-up components to understand the immunological footprint of a child and the consequences throughout life.

scholarly journals 407 - Living through the pandemic as an older person: Long-term psychological impacts in low- and middle-income countries

2021 ◽  
Vol 33 (S1) ◽  
pp. 33-33
Author(s):  
Clarissa Giebel ◽  
Bwire Ivan ◽  
Maria Isabel Zuluaga ◽  
Suresh Kumar ◽  
Mark Gabbay ◽  
...  
Keyword(s):  
Mental Health ◽  
Older Adults ◽  
Well Being ◽  
Middle Income ◽  
Middle Income Countries ◽  
Health And Social Care ◽  
The Impact ◽  
Low And Middle Income

Background:The pandemic has put a huge strain on people’s mental health, with varying restrictions affecting people’s lives. Little is known how the pandemic affects older adults’ mental health, particularly those living in low- and middle-income countries (LMICs) where restrictions are affecting people’s access to basic necessities. Thus, the aim of this 3-country study was to understand the long- term impacts of the pandemic on the mental well-being of older adults with and without dementia in LMICs.Methods:We are collecting 30 baseline and 15 follow-up interviews with older adults (aged 60+), people with dementia, and family carers in Colombia, India, and Uganda, as well as a baseline and follow-up focus group with health and social are professionals in each country. Interviews are conducted remotely over the phone due to pandemic restrictions, with data collection taking place between March and July 2021. Transcripts are translated into English before being analysed using thematic analysis.Results:To date, we have completed close to 90 baseline interviews and 3 focus groups with health and social care professionals. Analysis is ongoing, but findings are capturing the detrimental second wave in India and follow-up interviews will capture the longitudinal impacts on mental health.Conclusions:Whilst vaccines are starting to be rolled out in LMICs, albeit at different rates, the virus will likely take much longer to be somewhat managed in LMICs. This leaves more room for people’s physical as well as mental health to be impacted by the restrictions, and with often limited mental health service coverage, it is all the more important o understand the impact of the pandemic on older people’s mental health.

scholarly journals An emergency strategy framework for managing COVID-19 in long-term care facilities in Brazil

2021 ◽  
Vol 15 ◽  
Author(s):  
Peter Lloyd-Sherlock ◽  
João Bastos Freire ◽  
Meirelayne Duarte ◽  
Monica Frank ◽  
Karla Giacomin ◽  
...  
Keyword(s):  
Long Term Care ◽  
Policy Framework ◽  
Intersectoral Collaboration ◽  
Term Care ◽  
Middle Income ◽  
Local Implementation ◽  
Middle Income Countries ◽  
Care Facilities ◽  
The Impact

This paper presents a novel policy framework to support government responses to COVID-19 in long-term care facilities (LTCFs) in low and middle-income countries. It focuses on issues that are of specific relevance to Brazilian policy-settings, including examples of its local implementation. The CIAT Framework combines and summarizes broad elements for an emergency strategy to address the potential effects of COVID-19. The 4 steps of the Framework entail policies to coordinate, identify, assess, and target support. Those policies can be applied immediately to mitigate the impact of the COVID-19 pandemic in LTCFs. It is, however, essential to situate these responses within a more comprehensive and permanent strategy. Intersectoral collaboration must evolve into a fully institutionalized system.

Promoting Universal Social Policy in MICs

2020 ◽  
pp. 158-182
Author(s):  
Juliana Martínez Franzoni ◽  
Diego Sánchez-Ancochea
Keyword(s):  
Policy Design ◽  
Middle Income ◽  
Middle Income Countries ◽  
The Poor ◽  
Long Run ◽  
Poverty And Inequality ◽  
Political Struggles ◽  
The Right ◽  
The Impact

Most middle-income countries have the financial and institutional resources to reduce poverty and inequality and improve social capabilities. But what is the right policy approach to secure these goals? We argue that to be effective and successful, social policies should be universal, providing the whole population with similar, generous transfers and services. To explore how universal policies can be implemented, we distinguish between the desired policy outputs (coverage, generosity, and equity) and the specific ways to secure them. We then introduce the concept of the policy architecture and analyze its influence on long-term trajectories. The chapter considers the impact of different trajectories on universalism in the long run, distinguishing between a bottom-up strategy that starts from the poor or other alternatives that involve the non-poor from the onset. We conclude the chapter with a call for more research on the interactions between policy design and political struggles.

scholarly journals The Impact of the COVID-19 Crisis on Middle-income Countries

2021 ◽  
pp. 001946622110238
Author(s):  
Sukti Dasgupta ◽  
Mauricio Dierckxsens ◽  
Sher Verick
Keyword(s):  
Developing Countries ◽  
Informal Economy ◽  
Labour Force ◽  
Middle Income ◽  
Jel Codes ◽  
Middle Income Countries ◽  
Advanced Economies ◽  
The World ◽  
The Impact

Coming on top of long-term employment challenges, the COVID-19 crisis has severely impacted economies around the world. Due to the nature of their labour markets, middle-income countries (MICs), including India, have experienced greater employment declines than advanced economies. Some sectors have been hit harder than others, while certain groups—including women, youth, migrants and those in the informal economy—have felt the brunt of the crisis even more strongly. The crisis has raised unemployment and, even more, has also pushed many out of the labour force, raising inactivity. Overall, the crisis has exacerbated existing inequalities in countries and across countries. The major challenge for MICs is to finance the continuing efforts to battle the crisis while shifting to a job-rich and inclusive recovery. Key lessons have already emerged, which are relevant for India and other developing countries, including the importance of building a more resilient and inclusive labour market through strong institutions and policies. JEL Codes: E24, E60, G01, J08, J60

scholarly journals The Impact of COVID-19 on the Working Equid Community: Responses from 1530 Individuals Accessing NGO Support in 14 Low- and Middle-Income Countries

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1363
Author(s):  
Isabella Wild ◽  
Amy Gedge ◽  
Jessica Burridge ◽  
John Burford
Keyword(s):  
Household Income ◽  
Cross Sectional Study ◽  
Monthly Income ◽  
Cross Sectional ◽  
Daily Lives ◽  
Middle Income ◽  
Face To Face ◽  
Middle Income Countries ◽  
The Impact

The COVID-19 pandemic was declared on 11 March 2020. The working equid community includes some of the world’s most marginalised people, who rely on animals for their daily lives and livelihoods. A cross-sectional study investigated the effects of COVID-19 on working equid communities, with the intention of developing methods for replication in future unprecedented events. A multi-language survey was developed, involving 38 predominantly closed questions, and carried out face-to-face, over telephone, or online. There were 1530 respondents from a population of individuals who received support from equid welfare projects across 14 low- or middle-income countries projects during November and December 2020. Overall, at the time of survey completion, 57% (875/1522) of respondents reported that their equids were working less, 76% (1130/1478) reported a decreased monthly income from equids, and 78% (1186/1519) reported a reduction in household income compared to pre-pandemic levels. Costs of equid upkeep remained the same for 58% (886/1519) of respondents and 68% (1034/1518) reported no change in the health of their equid. The potential long-term impacts on human and equid welfare due to reported financial insecurities necessitates monitoring. A One Welfare approach, involving collaboration with governments, humanitarian, and animal welfare non-governmental organisations is required to mitigate deep-rooted issues.

Investment and Debt

2016 ◽  
Author(s):  
Layna Mosley
Keyword(s):  
Financial Integration ◽  
Economic Consequences ◽  
Short Term ◽  
Financial Openness ◽  
Middle Income ◽  
Middle Income Countries ◽  
Brics Countries ◽  
Political Determinants ◽  
The Impact

Abstract: This article examines the political determinants and economic consequences of financial openness in low- and middle-income countries, with emphasis on government autonomy rather than on other important outcomes such as economic growth and development. After sketching trends in financial openness in developing countries, the article illustrates how the effects of financial integration are intertwined with the type of capital flow (e.g., short-term versus long-term investment) and with a nation’s domestic interests and institutions. It then considers the possibility that BRICS countries (Brazil, Russia, India, China, and South Africa) will emerge as alternative financial leaders at a regional or global level. It also assesses the impact of capital flows on government-policy decisions and outcomes before reflecting on the politics of investment and debt.

The Impact of Covid 19 on Pregnant Women and Child Health

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1367-1373
Author(s):  
Nikhil Sanjay Mujbaile ◽  
Smita Damke
Keyword(s):  
Social Issues ◽  
Middle Income ◽  
Web Based ◽  
Middle Income Countries ◽  
Low Middle Income Countries ◽  
The Social ◽  
Social Separation ◽  
The Impact ◽  
And Child Health ◽  
General Wellbeing

The Covid illness (COVID-19) pandemic has spread rapidly all through the world and has had a drawn-out impact. The Pandemic has done incredible damage to society and made genuine mental injury to numerous individuals. Mental emergencies frequently cause youngsters to deliver sentiments of relinquishment, despondency, insufficiency, and fatigue and even raise the danger of self-destruction. Youngsters with psychological instabilities are particularly powerless during the isolate and colonial removing period. Convenient and proper assurances are expected to forestall the event of mental and social issues. The rising advanced applications and wellbeing administrations, for example, telehealth, web-based media, versatile wellbeing, and far off intuitive online instruction can connect the social separation and backing mental and conduct wellbeing for youngsters. Because of the mental advancement qualities of youngsters, this investigation additionally outlines intercessions on the mental effect of the COVID-19 Pandemic. Further difficulties in Low Middle-Income Countries incorporate the failure to actualize successful general wellbeing estimates, for example, social separating, hand cleanliness, definitive distinguishing proof of contaminated individuals with self-disconnection and widespread utilization of covers The aberrant impacts of the Pandemic on youngster wellbeing are of extensive concern, including expanding neediness levels, upset tutoring, absence of admittance to the class taking care of plans, decreased admittance to wellbeing offices and breaks in inoculation and other kid wellbeing programs. Kept tutoring is critical for kids in Low Middle-Income Countries. Arrangement of safe situations is mainly testing in packed asset obliged schools. 

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